Clinical trials: Trauma Abdomen
Hernia, Surgical Wound Dehiscence
Repair of Challenging Abdominal Wall Defects: Strattice(TM) TM in Abdominal Wall Repair (StAR)
The objective of this study is to compare the incidence of post-repair wound related complications, including hernia occurrence/recurrence, between challenging abdominal wall defects repaired with Strattice(TM) Reconstructive…
- Trial name
- StAR (NCT01083472)
- Testing
- Strattice(TM) Reconstructive Tissue Matrix, Suture/suture with absorbable mesh
- Where
- 29 sites in France, Germany and 4 more
- Volunteers
- 37 people
- Sponsor
- LifeCell
Gangrenous Appendicitis
Prophylaxis With Single Versus Five Dose of Antibiotic Therapy as Treatment of Patients With Gangrenous Acute Appendicitis
A prospective, randomized controlled clinical trial was conducted at the Hospital Universitario de Santander to test the effectiveness of providing a single 1-dose therapy of antibiotic prophylaxis versus a 5-day antibiotic…
- Trial name
- NCT01115153
- Testing
- prophylaxis, therapy
- Where
- Colombia
- Volunteers
- 150 people
- Sponsor
- Universidad Industrial de Santander
Laparotomy Closure After Abdominal Surgery
Comparing Delayed vs Primary Wound Closure After Emergency Laparotomy: Impact on Infection, Healing, and Hospital Stay
The purpose of this study is to find out which type of wound closure after emergency abdominal surgery leads to fewer wound infections and better recovery: closing the wound immediately after surgery (called primary closure) or…
- Trial name
- NCT07142395
- Testing
- Immediate skin closure, Delayed primary closure
- Where
- Pakistan
- Volunteers
- 82 people
- Sponsor
- Bkahtawar Amin Medical and Dental College Multan
MINS
PeriOperative Medicine - Metabolic Inflexibility as a Mechanism for Myocardial Injury After Non-Cardiac Surgery
The goal of this observational study is to learn whether metabolic inflexibility, which means reduced ability of the body to switch between using fats and sugars for energy, is associated with myocardial injury after non-cardiac…
- Trial name
- POM-MIMICS (NCT07694453)
- Testing
- Pre-operative Metabolic Inflexibility
- Volunteers
- 300 people
- Sponsor
- University College, London
Intra Abdominal Hypertension, Abdominal Compartment Syndrome
The Effect of Different Types of Temporary Abdominal Closure on Intra Abdominal Hypertension.
This is a prospective comparison trial. Patients that will be included in the trial are those that will have operations in which their abdominal closure is temporary, i.e. patients sustaining trauma or septic abdomen.
- Trial name
- TACACS (NCT02229695)
- Volunteers
- 42 people
- Sponsor
- Soroka University Medical Center
Peritonitis
Lavage With Super-Oxidized Solution for Secondary Peritonitis
Secondary peritonitis is a frequent abdominal emergency that is still associated with a high morbidity and mortality rate due to surgical site infections (SSI) and sepsis.
- Trial name
- SOSPeritonitis (NCT05050253)
- Testing
- Super-oxidized solution (SOS), Ringer's solution
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Hernia, Ventral
A Study to Compare Ventral Incisional Hernia by Laparoscopic vs Open Repair With Mesh
The purpose of this research is to compare open ventral incisional hernia repair to the laparoscopic repair with respect to complications, recurrence, pain, return to normal activities of daily living, and return to work.
- Trial name
- NCT00240188
- Testing
- Open mesh repair of ventral incisional hernia, Laparoscopic mesh repair of ventral incisional hernia
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- US Department of Veterans Affairs
Ascites, Blunt Abdominal Trauma
Telesonography Adaptation and Use to Improve the Standard of Patient Care Within a Dominican Community
The role of teleradiology has far reaching implications for the health of remote and underserved populations. The ability to coordinate radiographic evaluation and diagnosis from a distance has the potential to raise the standard…
- Conditions
- Ascites, Blunt Abdominal Trauma, Cholelithiasis, Cholecystitis
- Trial name
- NCT00591968
- Testing
- SonoSite Titan portable ultrasound coupled with email telediagnosis
- Where
- Dominican Republic
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Edward Via Virginia College of Osteopathic Medicine
Sepsis, Acute Lung Injury
Effect of S-ketamine Anesthetic on Inflammatory Response in Septic Patients Undergoing Abdominal Surgery
This study is a randomized, double-blinded, controlled design. In this study, low doses of S-ketamine were selected for surgury treatment in septic patients under general anesthesia , Meanwhile, activity of HO-1 protein …
- Trial name
- NCT04873479
- Testing
- S-ketamine, saline
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Tianjin Nankai Hospital
Wound Infection, Surgical
Clinical Outcome in View of Surgical Site Infection (SSI) With Antibacterial Skin Sutures
Background: Poor wound healing and the development of surgical site infection (SSI) continue to occur and remain a significant cause of disability among operated patients.
- Trial name
- NCT01540279
- Where
- Switzerland
- Volunteers
- 52 people
- Sponsor
- University Hospital, Basel, Switzerland
Appendicitis
European Society for Trauma and Emergency Surgery (ESTES) Cohort Study Snapshot Audit 2020 - Acute Appendicitis
Background Acute appendicitis is an extremely common surgical emergency. Traditionally, appendicitis has been managed surgically.
- Trial name
- SnapAppy (NCT04365491)
- Where
- Ireland
- Volunteers
- 4,000 people
- Sponsor
- Gary Alan Bass, MD PhD
Drug-induced Ototoxicity in Peritoneal Dialysis Patients
Prevention of Drug Induced Ototoxicity in Peritoneal Dialysis Patients by N-Acetylcysteine
The purpose of this study is to determine whether N-acetylcysteine is effective in the prevention of hearing loss in both ears due to aminoglycoside and/or vancomycine induced ototoxicity in peritoneal dialysis patients.
- Trial name
- NCT01131468
- Testing
- N-acetylcysteine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Traumatic Brain Injury, Blunt Abdominal Trauma
Impact of Traumatic Brain Injury on Hemodynamic Instability in Patients With Blunt Bowel and Mesenteric Injuries
This retrospective cohort study aims to evaluate the impact of traumatic brain injury (TBI) on hemodynamic status in trauma patients with surgically confirmed blunt bowel and mesenteric injuries (BBMI).
- Conditions
- Traumatic Brain Injury, Blunt Abdominal Trauma, Hemodynamic Instability, Shock
- Trial name
- NCT06942091
- Testing
- Traumatic Brain Injury (TBI)
- Volunteers
- 169 people
- Sponsor
- Chang Gung Memorial Hospital
Endometrial Adenocarcinoma
Effects of Wound Infiltration With Ketamine Versus Dexmedetomidine Added to Bupivacaine on Cytokines
This study aims to compare the effects of local wound infiltration with ketamine versus dexmedetomidine when added to bupivacaine on inflammatory cytokine response after total abdominal hysterectomy.
- Trial name
- NCT03164590
- Testing
- Ketamine, dexmedetomidine, bupivacaine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Diastasis of Muscle, Other Site
Abdominal Diastasis Repair by Robotic Surgery
The objective of the study is to evaluate the feasibility of a robot-assisted minimally invasive surgical technique for the management of diastasis of the rectus abdominis.
- Trial name
- PROMA1 (NCT04176874)
- Testing
- Robotic-assisted diastasis of the rectus abdominis muscles repair
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Surgical Wound Infection
Skin Perfusion After Abdominal Surgery
The purpose of this study is to evaluate the consequences of 3 selected surgical procedures on abdominal wall perfusion in order to help to reduce postoperative complication related to inadequate tissue perfusion.
- Trial name
- DIRTSURGERY (NCT03057249)
- Testing
- Dynamic infrared thermography (DIRT)
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- University Hospital of North Norway
Appendicitis Acute, Pediatrics
TAP Block Versus Local Anesthesia Wound Infiltration for Postoperative Pain Relief After Appendicectomy in Children
When performing laparoscopic appendectomy in children, regional anesthetic techniques are rou-tinely used concomitantly with general anesthesia.
- Conditions
- Appendicitis Acute, Pediatrics, Analgesia
- Trial name
- PABLO (NCT04969133)
- Testing
- Levobupivacaine Hydrochloride 2.5 MG/ML
- Where
- France
- Volunteers
- 110 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Dehiscence of Laparotomy Wound, Surgical Wound Infection
Short Stitch Monomax®
A number of studies identifies abdominal hernia as the most frequent postoperative complication following laparotomy with percentages of 9-20% - depending on duration of follow-up.
- Trial name
- Short-Stitch (NCT01938222)
- Testing
- Short Stitch
- Where
- Germany
- Volunteers
- 351 people
- Sponsor
- Diakonie-Klinikum Schwäbisch Hall gGmbH
Shock, Septic, Hyperlactatemia
Fluid REsponsiveness and Arterial ELASTANCE in Patients With Septic Shock or After Aortic Surgery
The MostCare system, thanks to the Pressure Recording Analytical Method (PRAM; Vygon, Padua, Italy), provides new hemodynamic parameters of the cardiovascular system.
- Conditions
- Shock, Septic, Hyperlactatemia, Oliguria, Aortic Aneurysm, Abdominal
- Trial name
- RELASTANCE (NCT04388267)
- Testing
- Fluid challenge
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Central Hospital, Nancy, France
Intensive Care Unit Patients, Pain Management
Effects of Voice Records on Patient Outcomes Surgical Intensive Care Unit
This randomized kontrolled study is aimed to contribute to the literature on recognising, evaluating and reducing stress in the intensive care unit, which is one of the main responsibilities of surgical nurses, and to increase…
- Conditions
- Intensive Care Unit Patients, Pain Management, Stress Response
- Trial name
- NCT07007754
- Testing
- Voice recording playback
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Aydin Adnan Menderes University