Clinical trials: Trauma Nervous System
Carpal Tunnel Syndrome
Carpal Tunnel Syndrome Treated With 830nm Diode Laser
The purpose of this study is to determine that 830nm diode laser directly above the transverse carpal ligament (between the pisiform and navicular bone) on subjects' wrists, and test this therapeutic effect.
- Trial name
- CTS (NCT00514462)
- Testing
- diode laser
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Spinal Cord Injury
Neural Adaptation After Tendon Transfer and Training in Tetraplegia
The number of people in the United States who have survived SCI is estimated to be approximately 273,000 persons. Around 50% of the injuries are to the cervical spine resulting in tetraplegia.
- Trial name
- NCT02768103
- Testing
- task-based training
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
REM Sleep Behavior Disorder, Concussion, Brain
The COSP-RBD Study: Concussions and Contact Sports in RBD vs Controls
The goal of this observational study is to investigate concussions and contact sports practices in REM sleep behaviour disorder (RBD).
- Trial name
- COSP-RBD (NCT06270290)
- Testing
- Exposure to contact sports or history of concussions
- Where
- United Kingdom
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Occupational Noise Exposure
OCCUPATIONAL NOISE AND CHEMICAL EXPOSURE EFFECTS ON AUDITORY AND VESTIBULAR FUNCTION
This study aims to investigate the effects of occupational noise exposure on hearing and auditory functions among individuals working in noisy environments.
- Trial name
- NCT07806123
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Musculoskeletal Pain, Osteoarthritis
Clinical Outcomes of Autologous Bone Marrow Aspirate Concentrate Injections for Musculoskeletal Conditions
The use of Bone Marrow Autologous Collection (BMAC) in musculoskeletal conditions including osteoarthritis and tendon injuries has been growing. Outcome evidence continues to be sparse.
- Conditions
- Musculoskeletal Pain, Osteoarthritis, Tendinopathy, Sprains Strain
- Trial name
- NCT02981394
- Testing
- Bone Marrow Aspirate Concentrate Injection
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Sport Related Concussion
Pilot Study on the Correlation Between Accelerations Experienced
Concussion, or mild traumatic brain injury, accounts for 85% of brain injuries and is common in both professional and amateur sports.
- Trial name
- BIOIMPACT (NCT07507253)
- Testing
- Analyze correlations between the measurements of the variations in biomarkers with those obtained by an instrumented mouthguard measuring accelerations.
- Where
- France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Sys2Diag
Postoperative Pain
Factors Influencing Postoperative Pain After Gingival Graft Harvesting
This prospective cohort study aims to evaluate patient-related, psychological, and clinical factors influencing postoperative pain following gingival graft harvesting from the palate.
- Trial name
- NCT07377370
- Testing
- Gingival graft harvesting from the palate
- Where
- Spain
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Spinal Cord Injuries, Neuropathic Pain
Capsaicin 8% Patch for Spinal Cord Injury Neuropathic Pain
A prospective case control study to determine the effectiveness and longevity of 8% capsaicin patch(es) in treating neuropathic pain in persons with spinal cord injury.
- Trial name
- Capsaicin (NCT02441660)
- Testing
- Capsaicin 8% Patch, Low Dose Capsaicin 0.025% Well Patch
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Brain Concussion
The Effect of Exercise on Neurorecovery Following Mild Traumatic Brain Injury
The study is a "proof-of-principle" project to examine the safety and feasibility of implementing a 1-week aerobic exercise program in the post-acute phase after mild traumatic brain injury (mTBI).
- Trial name
- NCT02276079
- Testing
- Aerobic Exercise, Non-Aerobic Exercise
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Florida
Traumatic Brain Injury, Post Traumatic Stress Disorder
Executive Dysfunction and Self-Harm Behavior: An Examination of Veterans With TBI, PTSD, or Both
1. To determine whether tasks taken from the field of cognitive neuroscience can detect and distinguish impairments in executive function above and beyond standard neuropsychological measures in individuals with: a.) Mild…
- Conditions
- Traumatic Brain Injury, Post Traumatic Stress Disorder, Suicide, Self-Injurious Behavior
- Trial name
- NCT01334463
- Where
- United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- VA Eastern Colorado Health Care System
Traumatic Brain Injury, Multiple Trauma
Evolution of Oropharyngeal and Rectal Microbiota After Severe Traumatic Brain Injury
Modifications of the human gut microbiota have been associated with different pathological conditions such as obesity, inflammatory bowel diseases and neurodegenerative diseases.
- Trial name
- BBAX (NCT03965611)
- Testing
- Oropharyngeal swab, Rectal swab, Disability rating scale (DRS-F)
- Where
- France
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Injury of Unknown Intent Due to Fall From Height, Traumatic Brain Injury
Addressing Attitudes to Improve Use of Protective Headwear in Older Adults
The goal of this phase of the project is to identify the elements of the Theory of Planned Behavior (TPB) that should be targeted to provide the most influence on older adults' behavior (or other stakeholders) to purchase and…
- Trial name
- AAIU-PHOA (NCT01582464)
- Testing
- Social Marketing for protective headgear
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Complex Regional Pain Syndrome, Carpal Tunnel Syndrome
Examination of the Pathophysiologic Mechanisms of CRPS by Using QST, CPM, RIC, and Heart Rate Variability QST
This study aims for a better understanding of the pathophysiological mechanisms of the complex regional pain syndrome (CRPS). This will be done by testing the quantitative sensory testing, the remote ischemic conditioning, the…
- Conditions
- Complex Regional Pain Syndrome, Carpal Tunnel Syndrome, Neuralgia
- Trial name
- NCT02261012
- Where
- Germany
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Ruhr University of Bochum
Traumatic Brain Injury
Therapeutic Resources for Attention Improvement With Neuroimaging for TBI
One of the most common symptoms suffered by traumatic brain injury (TBI) patients is disruption in attention. Lack of attention impacts daily life including academic or professional tasks, and interpersonal relationships.
- Trial name
- TRAIN-TBI (NCT02082509)
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Healthy, Traumatic Brain Injury
Investigating Event-Related Potentials and Eye-Tracking Measures in Hockey Players
Traumatic brain injury (TBI) is a health issue impacting athletes and no clinical treatment protocol, other than rest, is yet established.
- Trial name
- NCT03975023
- Testing
- NeuroCatch Platform (NCP)
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Frederick Carrick, PhD, FACCN
Traumatic Brain Injury (TBI), Healthy
Translocator Protein and Inflammation After Traumatic Brain Injury
Background: People with traumatic brain injury (TBI) often have inflammation in the brain. A protein called the translocator protein (TSPO) is often present with inflammation.
- Trial name
- NCT01547780
- Testing
- [11C]PBR28 and Positron Emission Tomography (PET)
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Post-traumatic Stress Disorder (PTSD), Cardiovascular Diseases
NightWare and Cardiovascular Health in Veterans With PTSD
The purpose of this study is to learn more about the effectiveness of a prescription wrist-wearable device called NightWare (NW) on improving sleep in Veterans with nightmares related to posttraumatic stress disorder (PTSD).
- Conditions
- Post-traumatic Stress Disorder (PTSD), Cardiovascular Diseases, Autonomic Dysfunction, Vascular Stiffness
- Trial name
- NCT06419959
- Testing
- NightWare
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Anxiety, Carpal Tunnel Syndrome
Effect of High-quality Pre-operative Videos on Patient Anxiety Levels Prior to Ambulatory Hand Surgery
Previous research has shown that YouTube is a poor source of high-quality medical information. This is likely because there is no regulation of the content on YouTube and relatively little of the content is posted by qualified…
- Conditions
- Anxiety, Carpal Tunnel Syndrome, Trigger Finger, Engagement, Patient
- Trial name
- NCT04424810
- Testing
- High-quality, physician created video, Standard of care
- Where
- United States
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Brain Injuries
D-aspartate and Therapeutic Exercise
An important mechanism responsible for clinical recovery after neurological damage of different types is synaptic plasticity. Nervous tissue can enhance or de-energize inter-neuronal transmission at synaptic level in a lasting…
- Trial name
- DAsp&TerapEx (NCT03228524)
- Testing
- D-Aspartate, Therapeutic exercise
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Neuromed IRCCS
Ocular Injury
Study of Retinal Vascular Changes After Ocular Blunt Trauma
This study evaluates the retinal vascular features using optical coherence tomography angiography in patients that received ocular blunt trauma.
- Trial name
- NCT04546997
- Testing
- Optical Coherence Tomography Angiography
- Where
- Italy
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Federico II University
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