Clinical trials: Trauma Prevention
Hypotension, Spinal Cord Injury
Prevention of Low Blood Pressure in Persons With Tetraplegia
The aim of this investigation is to determine the blood pressure response to NOS inhibition, with L-NAME, in persons with tetraplegia compared to non-SCI control subjects and to establish if blood pressure can be increased while…
- Trial name
- NCT00237770
- Testing
- N-Nitro L-arginine-methylester (L-NAME), Head-up Tilt maneuver
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Fall, Fall Injury
A Clinical Decision Support System and Patient Portal for Preventing Medication-related Falls in Older Patients
Falls in older adults represents a growing public health challenge. The use of certain medication is recognized as an important modifiable risk factor for falls.
- Conditions
- Fall, Fall Injury, Fall Patients, Accidental Fall
- Trial name
- ADFICE_IT (NCT05449470)
- Testing
- CDSS, Patient Portal
- Where
- 10 sites in Netherlands
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Stress, Trauma
STEP: Building Trauma Resilience Among Nurses and Personal Support Workers During and Beyond COVID-19
The COVID-19 pandemic has amplified the need for skills training and mental health support for healthcare workers who are exposed to the numerous stressors and potential trauma of a high-risk environment.
- Conditions
- Stress, Trauma, Mental Health Issue, Healthcare Workers
- Trial name
- NCT04682561
- Testing
- Supportive Trauma Exposure Preparation Program
- Where
- Canada
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Intrusive Thought, Psychological Trauma
Towards a Post-exposition Pharmacological Prophylaxis for Post-traumatic Stress Disorder
In this study, we investigate the role that deep sleep plays in the prevention of posttraumatic stress disorder after someone has been exposed to a trauma by boosting deep sleep with two drug conditions compared to placebo…
- Conditions
- Intrusive Thought, Psychological Trauma, Inflammatory Response, Physiological Stress
- Trial name
- TRAUMA-PRO (NCT04508166)
- Testing
- Dexmedetomidine, Gamma-Hydroxybutyrate, Experimental Model Trauma Film
- Where
- Switzerland
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Psychiatric University Hospital, Zurich
Osteoporosis, Accidental Falls
Geriatric Health Exam Osteoporosis Screening
BACKGROUND: The World Health Organization Fracture Risk Assessment Tool (WHO FRAX®) Taiwanese calculator is freely available on line to help osteoporosis management.
- Conditions
- Osteoporosis, Accidental Falls, Fracture
- Trial name
- NCT01934387
- Where
- Taiwan
- Volunteers
- 1,319 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Concussion
Interactive Training in Sports Concussion Prevention and Management
This study evaluated Brain 101: The Concussion Play book, an intervention that provides education and resources on concussion management for high schools.
- Trial name
- NCT01978795
- Testing
- Brain 101 website, Control
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Oregon Center for Applied Science, Inc.
Nonsuicidal Self-injury, Suicidal Ideation
Addressing Nonsuicidal Self-injury in Schools
The aim of this study is to study the effectiveness of a whole-school approach that addresses non-suicidal self-injury and targets adolescents, parents and teachers.
- Conditions
- Nonsuicidal Self-injury, Suicidal Ideation, Stigmatization, Help-Seeking Behavior
- Trial name
- NCT05935345
- Testing
- Addressing NSSI in schools, Control condition
- Where
- Sweden
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- Region Östergötland
Covid19, Burn Out
Burnout and Distress preventiOn With caNnabidiol in Front-line Health Care workerS deAling wIth COVID-19
The objective of this work is to monitor the level of stress and overload of a group of front-line health workers (physicians, nurses and physiotherapists) who will participate in the care of patients with COVID-19 at Hospital…
- Conditions
- Covid19, Burn Out, Post Traumatic Stress Disorder
- Trial name
- BONSAI (NCT04504877)
- Testing
- Cannabidiol
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Injuries
Tailoring a Home Supervision Intervention for Low-Income Families
The investigators will pilot test (N=100 caregivers of children ages 3-4 years) the effects of a caregiver supervision intervention on caregivers' supervision and children's injury frequency using a Randomized Controlled Trial…
- Trial name
- NCT03517475
- Testing
- SHS Low-Income
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Western Michigan University
Nephrotoxicity, Acute Kidney Injuries
Rutin and Ascorbic Acid for Prevention of Vancomycin-Induced Nephrotoxicity in Adult Patients" - a Clinical Trial Protocol Evaluating Whether Combined Rutin/Vitamin C Supplementation Reduces Kidney Toxicity From Vancomycin, Compared to Vitamin C Alone and Control.
Background: Vancomycin, a key antibiotic for MRSA infections, frequently causes nephrotoxicity (kidney damage) via oxidative stress, especially at the higher doses and longer durations now recommended.
- Trial name
- NCT07873372
- Testing
- Rutin + Ascorbic Acid (RUTA C60®), Ascorbic Acid (C-Retard®)
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Neuromuscular Control, Healthy
RIIP REPS Neuromuscular Training
The purpose of this study is to assess both the feasibility and efficacy of a 6-week mobile-application-based neuromuscular training program in high school athletes by measuring adherence rates and examining changes in agility…
- Conditions
- Neuromuscular Control, Healthy, Athletic Performance and Injury Risk
- Trial name
- NCT07221305
- Testing
- Neuromuscular Control Training
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Road Traffic Injury Prevention, Helmet Use
The Impact Of Text Message (SMS) Reminders On Helmet Use Among Motorcycle Drivers In Dar Es Salaam, Tanzania
This study seeks to evaluate the impact of a text-message (SMS) program delivered to motorcycle drivers in Dar es Salaam, Tanzania.
- Conditions
- Road Traffic Injury Prevention, Helmet Use, mHealth Intervention
- Trial name
- NCT02120742
- Testing
- SMS message reminder
- Where
- Tanzania
- Volunteers
- 391 people, healthy volunteers welcome
- Sponsor
- Amend
Athletic Performance, Plyometric Exercise
A Randomized Crossover Study on Diverse Training Methods to Enhance University Athletes' Performance and Health
The goal of this randomized crossover study is to investigate the effects of plyometric training, functional training, and whole-body electrical muscle stimulation (WB-EMS) on athletic performance and health in university…
- Conditions
- Athletic Performance, Plyometric Exercise, Healthy
- Trial name
- NCT06546605
- Testing
- Whole-Body Electrical Muscle Stimulation (WB-EMS) Training, Plyometric Training, Functional Training
- Where
- 2 sites in Macau
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Macau
Knee Valgus
Integrated Training Program On Jump Performance And Knee Valgus In Youth Football Players
This study aimed to investigate the effects of stretching, strength, and plyometric exercise training programs, applied in addition to regular training, on jumping performance and knee valgus values in football players.
- Trial name
- NCT07009041
- Testing
- Strength training program, Stretching exercises program, Plyometric exercises program
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Medical Device Site Erosion
Nursing Interventions on Prevention Medical Device Related Pressure Injury (MDRPI)
This study aims to assess the effect of implementing nursing interventions on preventing medical device related pressure injury in critically ill patients.
- Trial name
- MDRPI (NCT06513936)
- Testing
- The skin care Bundle, Routine care
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Damanhour University
Heat Illness, Quality of Life
Structural Heat Adaptation and Education in Rural Setting
This study aims to understand whether simple, low-cost interventions, such as improved home cooling, practical advice, and minor home modifications, can help protect people's health and quality of life during periods of extreme…
- Trial name
- SHAPES (NCT06983483)
- Testing
- Community education and awareness, Participatory local structural and environmental heat mitigation solutions
- Where
- Pakistan
- Volunteers
- 7,128 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Breast Cancer, Radiation Dermatitis
Efficacy Study With StrataXRT for the Prophylaxis of Radiation Dermatitis in Adjuvant Breast Radiation Treatment in Large Breasted Women Using a Prone Technique
For breast cancer patients undergoing adjuvant radiotherapy, radiation dermatitis (RD) is a common occurrence that can negatively impact patients' quality of life (QOL).
- Trial name
- NCT06865131
- Testing
- StrataXRT
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Falls Prevention, Prevention of Fall-related Injuries
Vitamin D and Exercise in Falls Prevention
The aim of the study is to investigate the effects of exercise and vitamin D supplementation on reducing falls and injuries in community-dwelling, independent-living women aged 70-79 years of age.
- Trial name
- DEX (NCT00986466)
- Testing
- exercise and vitamin D supplementation
- Where
- 2 sites in Finland
- Volunteers
- 409 people, healthy volunteers welcome
- Sponsor
- UKK Institute
Mouthguard Use, Orofacial Injuries Prevention
Impact of 3D-Printed and Custom Mouthguards on Speech and Oral Functions in Children Practicing Contact Sports
This study aims to compare the effects of traditional and 3D-printed custom-made mouthguards on speech and oral functions in pediatric cases who practice contact sports by evaluating the comfort, fit, and performance of both…
- Conditions
- Mouthguard Use, Orofacial Injuries Prevention, 3D Printed Mouthguard, Traditional Custom-made Mouthguard
- Trial name
- Mouthguards (NCT06972823)
- Testing
- 3D printed custom-made mouthguards, Traditional custom-made mouthguards
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Self-harm, Personality Disorder, Borderline
Self-harm Behaviour Among the Most At-risk Adolescents
In the proposed study, three objectives will be pursued: 1. To develop a method to identify more effectively the acute and long-term risk of adolescents with the most threatening self-harm behaviours. 2.
- Conditions
- Self-harm, Personality Disorder, Borderline, Epigenetic Disorder, Non-Suicidal Self Injury
- Trial name
- SH-MARA (NCT05765864)
- Testing
- Enrollment questionnaire, General questionnaire1, General questionnaire2, General questionnaire3, Columbia Suicide Severity Rating Scale (CSSRS), The Brief Non-Suicidal Self-Injury Assessment Tool (B-NSSI-AT)
- Where
- 2 sites in Slovenia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Ljubljana, Faculty of Medicine