Clinical trials: Trauma Prevention
Acute Kidney Injury
Spironolactone on Acute Kidney Injury in Critically Ill Patients
This study was designed to evaluate the effect of spironolactone administration in the incidence and severity of AKI in patients critically ill with invasive mechanical ventilation (IMV) in the critical care unit.
- Trial name
- NCT03206658
- Testing
- Spironolactone 25 mg
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Corneal Injuries
Peri-operative Application of Eyeprotx General Anesthesia Goggles As Prevention Against Corneal Injury Post Intubation.
This is a randomized controlled trial that seeks to examine the effectiveness of Eyeprotx™ protective goggles in comparison to traditional methods against ocular injury that can occur perioperatively under general anesthesia.
- Trial name
- NCT03762889
- Testing
- Eyeprotx™ General Anesthesia Protective Goggles, Eyelid Tape, Eye Ointment
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
Head and Neck Cancer, Radiotherapy Side Effect
The Characterisation of RT Caries.
Overcoming limitations of previous studies, the following research project will assess the most significant acute and long-term complications of RT that affect HNC patients: oral mucositis, dry mouth feeling, taste alteration and…
- Trial name
- NCT03397823
- Where
- United Kingdom
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- King's College London
Enhanced Child-safety Packaging
Efficacy of Flow Restrictors in Limiting Access of Liquid Medicines by Young Children
This study aimed to assess whether adding flow restrictors, adapters added to the neck of a bottle to limit the release of liquid, affects the proportion of preschool-aged children who can access liquid bottle contents, the…
- Trial name
- NCT06938620
- Testing
- Bottle with a flow restrictor, Control bottle
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Basketball Performance, Sports Injury Risk
Position-Specific Lower Limb Performance and AI-Based Injury Risk Analysis in Young Male Basketball Players
This observational study aims to evaluate lower extremity performance characteristics in young male basketball players according to their playing positions and to explore injury risk patterns using artificial intelligence…
- Conditions
- Basketball Performance, Sports Injury Risk, Lower Extremity Performance, Athletic Performance
- Trial name
- NCT07677371
- Testing
- Lower Extremity Performance Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Istanbul Gelisim University
Wounds and Injuries, Adolescent
Implementing a School Prevention Program to Reduce Injuries Through Neuromuscular Training
The purpose of this study is to evaluate the effectiveness of a neuromuscular training program in decreasing sport and recreational injuries and improving healthy outcomes in junior high school students (grades 7 to 9).
- Conditions
- Wounds and Injuries, Adolescent, Athletic Injuries, Sport Injury
- Trial name
- iSPRINT (NCT03312504)
- Testing
- Neuromuscular training program, Standard-of-practice Warm-up (Control)
- Volunteers
- 1,067 people, healthy volunteers welcome
- Sponsor
- Sport Injury Prevention Research Centre
Open Fractures
Antibiotic Prophylaxis in Open Fractures
Prospective look at antibiotic prophylaxis with Ceftaroline in patients with type II and III open fractures
- Trial name
- NCT02937181
- Testing
- Ceftaroline
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Olayemi Osiyemi MD
Healthy Subjects
Y-Balance Test Training for Ankle Function and Lower Limb Functional Performance
This randomized controlled study investigated whether a 6-week home-based training program based on the Y-Balance Test could improve ankle function and lower limb functional performance in university students.
- Trial name
- NCT07826312
- Testing
- Y-Balance Test-Based Training Program
- Where
- Portugal
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Aveiro University
ACL Injury Prevention
Effect of Specific ACL Injury Prevention Training in Female Handball Players
The anterior Cruciate Ligament (ACL) injuries rates in female handball are high, particularly among adolescents. Therefore, the primary purpose of this randomized control trial is to explore the effects of an 8-week ACL injury…
- Trial name
- NCT05955599
- Testing
- ACL Injury Prevention Training, Control - Shoulder Injury Prevention Training
- Where
- 3 sites in Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Hvidovre
Drowning
Improving Lifejacket Wear Among Boaters on Lake Albert, Uganda
A cluster randomized trial will be conducted for six months. To avoid covariate imbalance at baseline, stratified permuted block randomization with a 1:1 allocation ratio will be done.
- Trial name
- NCT05337761
- Testing
- Peer-led training on lifejacket wear
- Where
- Uganda
- Volunteers
- 387 people, healthy volunteers welcome
- Sponsor
- Makerere University
Traumatic Injury
Prevention of Injury in Military Settings Through the Use of Body Awareness.
The POSITION project aims to investigate the cognitive mechanism of postural body awareness as a risk factor for injury and as a target for a primary prevention strategy based on the Resource Optimization of Armed Forces (ROAF)…
- Trial name
- POSITION (NCT05451394)
- Testing
- ROAF, Active Comparator
- Where
- France
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Athletic Injuries
Analysis of Injury Risk Factors in Elite Athletes
Background information. The different disciplines of athletics place high physical demands on athletes. These different categories of running vary in terms of physical effort and duration, generating different levels of risk of…
- Trial name
- NCT06906666
- Testing
- Athletes sample
- Where
- Spain
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University of Oviedo
Sleep, Sleep Disturbance
Tech4Rest Trial With Team Truck Drivers
The current project is a safety and health intervention focused on sleep and fatigue among truck driver teams (pairs), where one driver sleeps in a moving vehicle while the other partner drives.
- Conditions
- Sleep, Sleep Disturbance, Sleep Disorder, Shift Work, Health Knowledge, Attitudes, Practice
- Trial name
- Tech4Rest (NCT03108599)
- Testing
- Enhanced Cab, Fit4Sleep
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Pressure Ulcer, Pressure Injury
What is the Incidence of Pressure Ulcer Category II-IV (Including Deep-tissue Injury and Unstageable) on a Static Air Foam Hybrid Mattress?
Pressure ulcers are a serious and common problem for residents admitted to long-term care facilities and community care patients.
- Conditions
- Pressure Ulcer, Pressure Injury, Pressure Sore, Bed Sore
- Trial name
- NCT05142878
- Testing
- Ultracore Repose® mattress
- Where
- 5 sites in Belgium
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University Ghent
Osteoarthritis, Hip, Femur Head Necrosis
Prophylaxis of Deep Vein Thrombosis Following Total Hip Arthroplasty
This prospective study compares an oral direct factor Xa inhibitor with LMWH for thromboprophylaxis in the patients undergoing THA.
- Conditions
- Osteoarthritis, Hip, Femur Head Necrosis, Femoral Neck Fractures
- Trial name
- NCT02379663
- Testing
- Rivaroxaban, Enoxaparin, Normal saline
- Volunteers
- 639 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Retained Surgical Items
Prevention of Retained Items iN Childbirth Environment and Surgical Sites
To evaluate the user confidence in the confirmation of correct counts using a novel device and to assess clinical usability of the device during surgery.
- Trial name
- PRINCESS (NCT06570304)
- Testing
- iCount Device
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Royal Wolverhampton Hospitals NHS Trust
HIV
Observational Study of Male Circumcision Using PrePex Device
The study will measure the incidence of moderate and severe adverse events (AEs) associated with PrePex procedures, including both procedural and post-procedure events, and all device-related incidents such as dislodgment.
- Trial name
- NCT01711411
- Testing
- PrePex device for male circumcision
- Where
- Kenya
- Volunteers
- 427 people, healthy volunteers welcome
- Sponsor
- FHI 360
Skin Stiffness, Skin Thickness
Evaluation Skin Stiffness Gradient on Skin After LLLT
This study evaluates the effects of Low-Level Laser Therapy (LLLT) on skin elasticity by measuring a 3x3 stiffness gradient across 9 points spaced 1 cm apart.
- Conditions
- Skin Stiffness, Skin Thickness, DFU, Wound and Injuries
- Trial name
- NCT07680309
- Testing
- LLLT intervention on skin biomechanical properties in different duration and wavelength, LLLT intervention on skin biomechanical properties in different duty cycle and applied frequency
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Asia University
Hip Fractures
Fragility Fracture Integrated Rehabilitation Management (FIRM)
A number of studies for clinical pathway (CP) after hip fracture have been suggested to improve post-fracture outcome. However, CP is not carried out properly in most countries due to inadequate system and awareness, and lack of…
- Trial name
- FIRM (NCT03430193)
- Testing
- FIRM, Conventional rehabilitation
- Where
- South Korea
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Osteoporosis, Bone Diseases, Metabolic
Patient Activation After DXA Result Notification
There is growing evidence that patients undergoing bone mineral density testing (BMD) often do not take important steps to improve their bone health.
- Trial name
- PAADRN (NCT01507662)
- Testing
- Bone Mineral Density Result Letter and Bone Health Brochure
- Where
- 4 sites in United States, Canada
- Volunteers
- 7,749 people, healthy volunteers welcome
- Sponsor
- Fredric D Wolinsky