Clinical trials: Trauma Prevention
Contrast-induced Acute Kidney Injury, Cardiovascular Diseases
The Role of Statins in the Prevention of Contrast-induced Acute Kidney Injury in Patients With Cardiovascular Diseases
The aim of the study is to assess the role of statins and different dosage regimens in the prevention of contrast-induced acute kidney injury in patients with cardiovascular diseases requiring intravenous contrast media…
- Trial name
- NCT04666389
- Testing
- Atorvastatin
- Where
- Russia
- Volunteers
- 150 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Radiodermatitis; Acute
Use of Topical Olive Oil Cream for Prophylaxis Against Acute Radiodermatitis in Breast Cancer Patients
This study aims to compare the prophylactic effect of topical betamethasone valerate cream and topical olive oil cream in the prevention of acute radiation dermatitis (ARD) in breast cancer patients treated with radiation.
- Trial name
- NCT05285943
- Testing
- Olive oil cream, Betamethasone Valerate Cream, Base Cream
- Where
- Egypt
- Volunteers
- 132 people
- Sponsor
- Cairo University
Accidental Falls, Fractures
Clinical Evaluation of a Wireless Monitoring Device to Reduce Falls in the Elderly and Others at High Risk of Falling
Falls are a public health problem of significant social and economic significance. No primary intervention devices have been shown to be effective in reducing falls and associated injuries.
- Conditions
- Accidental Falls, Fractures, Injuries
- Trial name
- NCT00249743
- Testing
- FallSaver (formerly called NOCwatch)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- NOCwatch International
Surgical Site Infection, Brain Tumor
Infection Prevention Bundle in Brain Tumor Surgery
This study aimed to evaluate the effectiveness of an infection prevention bundle on surgical site infections in patients undergone brain tumor surgery.
- Trial name
- NCT04285697
- Testing
- infection prevention bundle
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Compartment Syndrome
Study of New Catheter & Pressure Monitor System to Help Prevent Compartment Syndrome From Developing in the Injured Leg
An investigation of a new catheter and pressure monitor system that may help to prevent a complication called compartment syndrome from developing in an injured leg.
- Trial name
- TS2 (NCT00681616)
- Testing
- Compartment Monitoring System (CMS), Compartment Monitoring System with Active Fluid Removal, Compartment Monitoring System without fluid removal
- Where
- 13 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Twin Star Medical, Inc.
Wound, Donor Site Complication
Clinical Efficacy and Safety of Sericin Hydrogel Sheet Impregnated With Bird's Nest Extract
Split-thickness skin graft (STSG) is one of the most common procedures performed in plastic surgery and dermatology. The donor site of skin grafting is expected to heal without scarring.
- Conditions
- Wound, Donor Site Complication, Skin Graft Scar, Scar Conditions and Fibrosis of Skin
- Trial name
- NCT04997863
- Testing
- Sericin hydrogel sheet impregnated with EBN extract
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Chulalongkorn University
Pain, Postoperative, Rebound Pain
Intravenous Dexamethasone With Single-Shot Versus Continuous Brachial Plexus Block for Rebound Pain After Shoulder Surgery
Shoulder surgery often causes severe pain after the operation. To control this pain, doctors commonly perform a nerve block (interscalene brachial plexus block), which numbs the shoulder area.
- Conditions
- Pain, Postoperative, Rebound Pain, Shoulder Injuries, Rotator Cuff Injuries
- Trial name
- NCT07699744
- Testing
- Dexamethasone (IV), Single-shot interscalene brachial plexus block, Continuous interscalene brachial plexus block
- Where
- South Korea
- Volunteers
- 92 people
- Sponsor
- Seoul National University Hospital
Cervical and Mandibular Pain and Disorders in Wind Players
Prevention of Musculoskeletal Injuries in Musicians
Musicians are a group with a high prevalence of musculoskeletal injuries. In particular, wind musicians, due to their playing requirements, are prone to suffer from cervical and mandibular alterations.
- Trial name
- NCT05277649
- Testing
- Exercise programme
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Margarita Pino Juste
Acute Stress Disorder
Efficacy of Prazosin in Preventing Post-traumatic Stress Disorder
After a traumatic event such as an accident or an assault, victims may experience intense stress symptoms that may evolve into "post-traumatic stress disorder" (PTSD).
- Trial name
- PRAZOSTRESS (NCT03045016)
- Testing
- Prazosin, ALPRESS® LP 2,5 et 5 mg
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Hospices Civils de Lyon
Colon Cancer, Rectal Cancer
Pilot Study Evaluating the Efficacy of AlloMEM After Loop Ileostomy
The objective of this study is to investigate whether the use of Human Peritoneal Membrane (HPM) in a temporary loop ileostomy is beneficial to patients.
- Trial name
- AlloMem (NCT01113736)
- Testing
- AlloMEM™
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Road Traffic Injury Prevention, Motorcycle Safety, Personal Protective Equipment Use, Visibility Materials, Injury Prevention Education, Health Behavior Change
The Effectiveness of Health Education Intervention in Enhancing Personal Protective Equipment Use
This study is testing whether a health education program can help commercial motorcycle riders and passengers in the Limbe and Tiko Health Districts of Cameroon improve their use of safety equipment.
- Trial name
- NCT07087444
- Testing
- Health education intervention to improve knowledge and uptake of personal protective equipment and visibility materials among commercial motorcycle riders and passengers
- Where
- Cameroon
- Volunteers
- 967 people, healthy volunteers welcome
- Sponsor
- University of Buea
Sharps Injuries
A Study of VAX-ID® 2200, a New Device for Intradermal Injections
The researchers are doing this study to find out whether the VAX-ID® 2200 device is safe and easy to use for healthcare professionals who give intradermal injections.
- Trial name
- NCT07898111
- Testing
- VAX-ID® 2200
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer, Radiation Dermatitis
Randomized Phase III Trial With Mepitel Film for the Prophylaxis of Radiation Dermatitis in Breast Cancer Patients
Breast cancer patients undergoing adjuvant radiotherapy commonly experience radiation-induced skin reactions which adversely impact quality of life.
- Trial name
- NCT04166799
- Testing
- Mepitel Film
- Where
- Canada
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Osteoporosis
Osteoporosis Prevention: Changes to Exercise and Diet in Children
The purpose of this study is to determine whether educating parents about health and behavior management techniques will increase physical activity, calcium intake, fitness, and bone density in their children.
- Trial name
- NCT00063050
- Testing
- Physical activity and nutrition intervention
- Where
- United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Blood Flow Restriction Training, Eccentric Training
BFR Training on Muscle Morphology
This randomized clinical trial study compares high-load eccentric training (HL-Et), sham LL-BFRt, and low-load blood flow restriction (LL-BFRt) in sportsmen.
- Conditions
- Blood Flow Restriction Training, Eccentric Training, Muscle Morphology, Patellofemoral Pain Syndrome
- Trial name
- NCT06566950
- Testing
- Low load-BFRt, High load-Eccentric training
- Where
- Indonesia
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Udayana University
Surgical Site Infection, Surgical Wound Infection
Floraseal Versus Iodine Impregnated Adhesive Drapes
Infection after total joint arthroplasty can have devastating consequences. Adhesive drapes have been traditionally used at our institution to help reduce the risk of wound contamination and infection by superficial skin flora.
- Trial name
- NCT03466489
- Testing
- Floraseal
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma), Elderly
Cardiovascular Prevention Strategies in Elderly Patients With Cancer (CARTIER Clinical Trial)
The CARTIER study is a randomized, multicenter, open-label clinical trial comparing, in elderly patients with cancer under anti-tumoral treatment, two different cardiotoxicity prevention strategies: primary (intensive…
- Conditions
- Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma), Elderly, Antineoplastic Agents, Cardiotoxicity
- Trial name
- CARTIER (NCT03711110)
- Testing
- Intensive cardiovascular monitoring, No intervention
- Where
- 14 sites in Spain
- Volunteers
- 514 people
- Sponsor
- Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León
Motor Vehicle Occupant Injury, Teenaged Driver
Parent-based Intervention to Increase Safe Teen Driving
We hypothesize that this intervention will increase the quality and quantity of parental interaction on safety driving with newly-licensed teen drivers.
- Trial name
- NCT01014923
- Testing
- Teen driving intervention
- Where
- 2 sites in United States
- Volunteers
- 163 people
- Sponsor
- University of Iowa
Atrial Fibrillation
Esophageal Cooling for AF Ablation
The purpose of this study is to determine if esophageal cooling using the Attune Medical Esophageal Heat Transfer Device (EnsoETM) limits the number or seriousness of injury to the esophagus during atrial fibrillation ablation…
- Trial name
- eCoolAF (NCT03691571)
- Testing
- Esophageal Cooling, Control
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of Pennsylvania
Open Fracture
Placement of Antibiotic Powder in Wounds During the Emergency Room
This is the first prospective controlled study to determine whether the topical application of vancomycin powder reduces infection-related complications when applied to open fracture injuries in the acute emergency department…
- Trial name
- POWDER (NCT03765567)
- Testing
- Vancomycin
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
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