Clinical trials: Traumatic Injuries
Concussion, Traumatic Brain Injury
Concussion Device Audiological Measures
Significant morbidity, mortality, and related costs are caused by traumatic brain injury (TBI). A simple, effective, and lightweight device worn by athletes or war fighters in the field, designed to mitigate TBI resulting from…
- Trial name
- NCT02262507
- Testing
- Device Wearing
- Volunteers
- 410 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Posttraumatic Stress Disorder
Using Wearable Technology to Detect Symptoms of Posttraumatic Stress Disorder
The aim of the project is to advance our understanding of how individuals with Posttraumatic Stress Disorder (PTSD) experience symptoms in their every-day lives when they are in their home environment.
- Trial name
- NCT05534100
- Testing
- Biostrap EVO Wristband
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Posttraumatic Stress Disorder
GAMBIT Task With PTSD and Healthy Control Participants
This is a pilot study of a digital training task called GAMBIT. This study will be the first to examine potential relationships between GAMBIT task completion and brain circuit flexibility, behavior, and symptoms in participants…
- Trial name
- GAMBIT (NCT05313334)
- Testing
- GAMBIT Task
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Focused Stress
Identification and Comprehension of Focused Stress in a Sentence Among Adults Who Suffered Traumatic Brain Injury
Researches that focus on the perception of prosodic elements among adult who suffered traumatic brain injury (TBI), focus on their ability to decipher intonation in order to understand an additional meaning of a sentence.
- Trial name
- NCT02499133
- Testing
- language and cognitive tests
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Injury of Unknown Intent Due to Fall From Height, Traumatic Brain Injury
Addressing Attitudes to Improve Use of Protective Headwear in Older Adults
The goal of this phase of the project is to identify the elements of the Theory of Planned Behavior (TPB) that should be targeted to provide the most influence on older adults' behavior (or other stakeholders) to purchase and…
- Trial name
- AAIU-PHOA (NCT01582464)
- Testing
- Social Marketing for protective headgear
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Posttraumatic Stress Disorder, Major Depressive Disorder
Risk and Resiliency Factors in the RCMP: A Prospective Investigation
The Royal Canadian Mounted Police (RCMP), like all public safety personnel (PSP), are frequently exposed to potentially psychologically traumatic events that contribute to posttraumatic stress injuries (PTSI).
- Conditions
- Posttraumatic Stress Disorder, Major Depressive Disorder, Panic Disorder, Generalized Anxiety Disorder
- Trial name
- NCT05527509
- Testing
- Emotional Resilience Skills Training (ERST), Active Monitoring
- Where
- Canada
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- University of Regina
Pain, Traumatic Brain Injury
The NRC Dataset. Developing a Minimum Dataset for Multidisciplinary Rehabilitation: a Modified E-Delphi Study
Several rehabilitation datasets are presently in use for specific patient groups in England. The 'National Clinical Audit of Specialist Rehabilitation for patients with complex needs following major injury' (NCASRI) evaluated…
- Conditions
- Pain, Traumatic Brain Injury, Major Trauma, Multiple Sclerosis
- Trial name
- NCT06726135
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- ThomasCorbett
TBI
Neural and Behavioral Sequelae of Blast-Related Traumatic Brain Injury
Hypothesis 1: On fMRI scanning, frontoparietal activation during performance of executive function tasks of working memory, inhibitory control processes, and stimulus-response interference will exhibit greater signal intensity, a…
- Trial name
- NCT04012463
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Intrusive Thoughts, Post Traumatic Stress Disorder
Reduction of Trauma-induced Intrusions and Amygdala Hyperreactivity Via Non-invasive Brain Stimulation
The study will focus on the modulation of intrusive memories via functional magnetic resonance imaging (fMRI)-guided repetitive transcranial magnetic stimulation of the dorsolateral prefrontal cortex (dlPFC) directly after…
- Trial name
- COOL (NCT04325087)
- Testing
- iTBS
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bonn
Post Traumatic Stress Disorder
The Effects of Very Brief Exposure on PTSD in U.S. Combat Veterans
The goal of this clinical trial is to develop a new behavioral treatment for U.S. combat veterans with post-traumatic stress disorder (PTSD), very brief exposure to combat-related stimuli.
- Trial name
- PTSD (NCT06218381)
- Testing
- Very Brief Exposure to Combat Images
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Traumatic Lung Injury, Inhalation Injury
Selecting Specific Bio-markers and Researching Mechanisms of Immune Regulation From Inhalation Injury and Traumatic Lung Injury Based on Single Cell Sequencing Technology
The goal of this observational study is to profile the circulating immunological traits of patients with traumatic lung injury (TLI) and inhalation injury (ILI),providing a new direction for the depth research of the…
- Trial name
- NCT05718830
- Where
- China
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Coma, Traumatic
Dopaminergic Disruption Induced by Traumatic Coma: Dopaminergic Pathways Abnormalities and Biomarkers of Recovery Using MRI and 18F-LBT-999 PET
The neural correlates of consciousness have been studied at the macroscopic level. However, the neurochemical basis of these processes remains poorly understood.
- Trial name
- ComaDopa (NCT06930261)
- Testing
- LBT-999
- Where
- France
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Aggression, Post Traumatic Stress Disorders
Strength at Home Couples Program (PTSD-Focused Relationship Enhancement Therapy for Returning Veterans)
The purpose of the project is to develop and test a couples-based relationship enhancement group intervention for married or partnered Operation Enduring Freedom (OEF)/Operation Iraqi Freedom (OIF)/Operation New Dawn (OND)…
- Trial name
- NCT00827879
- Testing
- Strength at Home Couples Group, Supportive Group Therapy
- Where
- 2 sites in United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Boston VA Research Institute, Inc.
PTSD
Clinical Assessment of the Flash - Eye Movement Desensitization and Reprocessing
To assess the Flash version of EMDR in reductions of the disturbance of upsetting memories at post-intervention, and 1-month follow up within a double-blinded, online 2-arm randomized controlled trial (RCT) with self-report…
- Trial name
- Flash-EMDR (NCT05262127)
- Testing
- Flash Version of EMDR
- Where
- 2 sites in Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- York University
Concussion
Cortical Plasticity Assessment in Athletes With a History of Concussion
The purpose of this research is to determine whether athletes with concussion have changes in cortical excitability. Single and paired transcranial magnetic stimulation (TMS) can be used as reliable neurophysiological marker of…
- Trial name
- NCT01112761
- Testing
- Transcranial direct current stimulation
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Post Traumatic Stress Disorder
Perceptions of MDMA-Assisted Therapy Among Veterans With PTSD
The goal of this exploratory, mixed-method design study is to gather qualitative and quantitative data obtained through interviews and questionnaires with veterans who are currently enrolled at the VA for healthcare.
- Trial name
- PMATAVP (NCT05895318)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Albany Research Institute, Inc.
Stress Disorders, Post-Traumatic
Gene Expression Correlates of Post-Traumatic Stress Disorder (PTSD) Symptom Change After EFT (Emotional Freedom Techniques)
The purpose of the study is to measure the change in psychological symptoms and gene expression in war veterans after a series of 10 EFT coaching sessions.
- Trial name
- NCT01250431
- Testing
- EFT (Emotional Freedom Techniques)
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Soul Medicine Institute
Convergence Insufficiency
Home-based Vision Therapy
Post-concussive vision symptoms affect many Veterans who have experienced traumatic brain injury (TBI). One common issue is trouble with near vision, a problem that may persist long after the acute injury.
- Trial name
- NCT06886737
- Testing
- Virtual-reality convergence training game
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Dizziness, Brain Injury
Vestibular Consequences of Blast-related Mild Traumatic Brain Injury (TBI)
The purpose of this project is to determine the effects of mild traumatic brain injury and blast exposure on the inner ear balance and central nervous systems.
- Trial name
- NCT01021137
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Earthquake, Stress Disorders, Post-Traumatic
The Effect of Exercise on Post-traumatic Stress Disorder and Sleep Quality in Individuals Affected by the 2023 Kahramanmaraş Earthquakes
Natural disasters can have adverse impacts on both physical and mental health. Post-traumatic stress disorder (PTSD) and sleep disorders are among the most common problems seen after natural disasters.
- Trial name
- NCT06388876
- Testing
- Exercise, lifestyle advice
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.