Clinical trials: Traumatic Injuries
Persistent PostConcussion-Like Symptoms, Post-Traumatic Stress Disorder
Persistent PostConcussion-Like Symptoms and Post Traumatic Stress Disorder in Patients Presenting at the Emergency Room.
Promising results of an early EMDR (Eye Movement Desensitization and Reprocessing) intervention on PCLS (PostConcussion-Like Syndrome) at three months have been shown, suggesting that the availability of psychological care in…
- Trial name
- SOFTERIV (NCT04916678)
- Testing
- R-TEP EMDR intervention
- Where
- 7 sites in France
- Volunteers
- 2,897 people
- Sponsor
- University Hospital, Bordeaux
Traumatic Brain Injury, Subarachnoid Hemorrhage
Comparison of Narcotrend and Cerebral Function Analysing Monitor in Intensive Care to Monitor Seizures and Deep Sedation
A study in the use of the Narcotrend depth of anaesthesia monitor to record a) seizures, and b) monitor a level of sedation referred to as 'burst suppression', in sedated patients in the adult and paediatric intensive care.
- Conditions
- Traumatic Brain Injury, Subarachnoid Hemorrhage, Intracerebral Haemorrhage, Encephalitis
- Trial name
- NCT06067750
- Testing
- Narcotrend compared to Cerebral Function Analysing Monitor (CFAM)
- Where
- United Kingdom
- Volunteers
- 44 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Stress Reaction; Acute
Racial Discrimination and Stress Response
The goal of this study is to learn about whether ethnic minority adolescents' racial discrimination experience is related to dysregulated biological responses to subtle racism, and how the relationship may be attenuated or…
- Trial name
- NCT05820659
- Testing
- peer rejection task, conversation about peer rejection, and impossible puzzle task
- Where
- United States
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Western Kentucky University
Posttraumatic Stress Disorder
Cognitive Remediation in Posttraumatic Stress Disorder (PTSD)
The purpose of this study is to gather feasibility data on cognitive remediation therapy (CRT) as an alternative intervention for PTSD.
- Trial name
- NCT00850447
- Testing
- Cognitive Remediation Therapy, Videogame
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Bronx VA Medical Center
Posttraumatic Stress Disorder (PTSD)
Effects of Paxil CR on Neural Circuits in Posttraumatic Stress Disorder (PTSD)
Posttraumatic stress disorder (PTSD) is a major public health problem in this country. It is estimated that at least one out of every seven women in our society have been the victim of childhood sexual abuse at least once before…
- Trial name
- NCT00672776
- Testing
- paroxetine
- Volunteers
- 40 people
- Sponsor
- Emory University
Traumatic Brain Injury, Coma
The Efficacy of Familiar Voice Stimulation During Coma Recovery
The purpose of the study is to determine whether familiar vocal stimulation, provided during coma recovery, improves outcomes for persons who are unconscious after severe TBI.
- Conditions
- Traumatic Brain Injury, Coma, Vegetative State, Minimally Conscious State
- Trial name
- FAST (NCT00557076)
- Testing
- Familiar Auditory Sensory Training
- Where
- 3 sites in United States
- Volunteers
- 21 people
- Sponsor
- VA Office of Research and Development
Concussion, Brain
Developing an Implementation Strategy for Post-concussion Communication With Low Health Literacy Parents in the Emergency Department
Investigators will conduct a hybrid implementation-effectiveness evaluation of an educational intervention that supports communication with families post-concussion in the emergency department.
- Trial name
- NCT04112914
- Testing
- Post-concussion education for families
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Traumatic Brain Injury
Effect of Recombinant Erythropoietin on Numbers of Circulating Endothelial Progenitor Cells in People With Persistent Symptoms During the Subacute Period After Traumatic Brain Injury
Background: Traumatic brain injury (TBI) injures blood vessels in the brain. Endothelial progenitor cells (EPCs) help the body form new blood vessels.
- Trial name
- NCT02226848
- Testing
- Erythropoeitin
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Post-Traumatic Stress Disorder
Hydrocortisone for Prevention of Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder (PTSD) is an acquired psychiatric condition that occurs after exposure to a dangerous or life-threatening event.
- Trial name
- HP-PTSD (NCT02402114)
- Testing
- Hydrocortisone
- Where
- United States
- Sponsor
- Albert Einstein Healthcare Network
Depressive Symptoms, Anxiety
The Impact of PM+For Moms Intervention on Improving Mother's Mental Health in Zambia (PM+FM)
CMHD are particularly prevalent among women, posing a major threat to their own and their children's wellbeing. Despite the high prevalence of CMHD and the existence of effective treatments, interventions supporting women living…
- Conditions
- Depressive Symptoms, Anxiety, Trauma, Psychological
- Trial name
- PM+FM (NCT05627206)
- Testing
- Problem Management + For Moms
- Where
- Zambia
- Volunteers
- 270 people
- Sponsor
- Swiss Tropical & Public Health Institute
Traumatic Brain Injury
Efficacy of Stellate Ganglion Block in Traumatic Brain Injury Patients
The goal of this or clinical trial is to explore efficacy of stellate ganglion block on dysphagia and activities of daily living in Traumatic Brain Injury Patients.
- Trial name
- NCT06319638
- Testing
- Rehabilitation therapy, Stellate ganglion block, Lidocaine Hydrochloride
- Volunteers
- 100 people
- Sponsor
- Copka Sonpashan
Commotio Cerebri, Mild Traumatic Brain Injury
Get Going After concussioN 2.0
The study tests the promising results of a previous study (GAIN 1.0) in a larger RCT (GAIN 2.0) which takes place in the municipalities of Central Denmark Region where citizens live their daily lives and whose health- and social…
- Trial name
- GAIN2 (NCT04798885)
- Testing
- GAIN 2.0
- Where
- Denmark
- Volunteers
- 310 people
- Sponsor
- University of Aarhus
Awareness, Mechanical Ventilation
The ED-AWARENESS-2 Trial
The investigators will screen all mechanically ventilated ED patients for study eligibility and will enroll all consecutive patients satisfying inclusion and exclusion criteria.
- Conditions
- Awareness, Mechanical Ventilation, Intubation Complication, PTSD
- Trial name
- ED-AWARENES II (NCT05534243)
- Testing
- Standard neuromuscular blocker practices, Education
- Where
- 4 sites in United States
- Volunteers
- 3,212 people
- Sponsor
- Washington University School of Medicine
Multiple Trauma
Relationship Between Erythropoietin Administration and Stress Responses in Trauma Patients
The purpose of this study is to determine whether Erythropoietin decrease stress responses and inflammation in trauma patient.
- Trial name
- EPREX (NCT00622934)
- Testing
- erythropoietin
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Tehran University of Medical Sciences
Schizophrenia, Major Depression
Procedures for Sample Acquisition and Distribution for The Human Brain Collection Core
Background: The Human Brain Collection Core (HBCC) collects brain and other tissues. They get these from deceased people who may or may not have had psychiatric disorders.
- Conditions
- Schizophrenia, Major Depression, Bipolar Disorder, PTSD
- Trial name
- NCT03092687
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- National Institute of Mental Health (NIMH)
PTSD
Comparison of Ericksonian Hypnotherapy and CBT in PTSD: A Clinical Trial
Brief Summary (Plain Language) The goal of this clinical trial is to compare the effects of Ericksonian Hypnotherapy and Cognitive Behavioral Therapy (CBT) on people diagnosed with Post-Traumatic Stress Disorder (PTSD).
- Trial name
- NEPTUNE (NCT06761716)
- Testing
- Ericksonian Hypnotherapy, Cognitive Behavioral Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Uskudar University
Traumatic Spinal Cord Injury, Tetraplegia/Tetraparesis
NIBS Therapy in Subacute Spinal Cord Injury
No accepted clinical therapies exist for repair of motor pathways following spinal cord injury (SCI) in humans, leaving permanent disability and devastating personal and socioeconomic cost.
- Trial name
- NIBS-SCI1 (NCT06247904)
- Testing
- Active rTMS
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Albert Einstein Healthcare Network
PTSD, TBI
Study of PTSD in Military Veterans Who Have Suffered Traumatic Brain Injuries
Treatment for veterans who have had a traumatic brain injury (TBI) and who are suffering from post traumatic stress syndrome (PTSD) is varied with varied outcomes.
- Trial name
- PTSD-TBI (NCT02003352)
- Testing
- Functional Neurological Rehabilitation
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- Carrick Institute for Graduate Studies
Fibrinogen, Albumin
Fibrinogen-to-Albumin Ratio as a Predictor of Acute Respiratory Distress Syndrome in Traumatic Brain Injury
this study aims to assess the ability of fibrinogen-to-albumin ratio to predict the development of Acute respiratory distress syndrome in traumatic brain injury patients.
- Conditions
- Fibrinogen, Albumin, ARDS, TBI (Traumatic Brain Injury)
- Trial name
- FARDS (NCT07664358)
- Testing
- Fibrinogen-to-albumin ratio
- Where
- Egypt
- Volunteers
- 350 people
- Sponsor
- Tanta University
Traumatic Shock, Hemorrhagic Shock
Prehospital Norepinephrine and Early Mortality in Traumatic Shock
The effect of early, prehospital norepinephrine use in patients with traumatic shock on mortality is unknown. Recent existing observational evidence from single system data (US, France, Japan) are conflicting.
- Conditions
- Traumatic Shock, Hemorrhagic Shock, Traumatic Brain Injury, Hypotension and Shock
- Trial name
- NCT04497155
- Testing
- Norepinephrine
- Volunteers
- 2,164 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
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