Clinical trials: Treatment Levothyroxine
Chronic Prostatitis
Non Interventional Study of Levofloxacin in Chronic Prostatitis
Chronic prostatitis is a common disease in men with the following typical symptoms decreasing the ability to work and quality of life: pain, urination disorders, copulatory dysfunction.
- Trial name
- Levolet-R (NCT02711943)
- Testing
- Levofloxacin 500
- Volunteers
- 500 people
- Sponsor
- Dr. Reddy's Laboratories Limited
Hypothyroidism
Interaction Between Levothyroxine and Probiotics in Hypothyroid Patients
A prospective, randomized, single-blind, controlled, investigator-started clinical trial was carried out. Patients with primary hypothyroidism were randomly assigned to the study (VSL#3®+ LT4) and the control group (LT4).
- Trial name
- NCT03095963
- Testing
- a mixture of highly charged Lactobacilli and Bifidobacteria (VSL#3®), levothyroxin
- Volunteers
- 80 people
- Sponsor
- Azienda USL Modena
PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries, Subclinical Hypothyroidism
Best Treatment for Women With Both (Polycystic Ovary Syndrome) PCOS and Subclinical Hypothyroidism
The goal of this randomized controlled trial is to compare letrozole alone versus letrozole plus levothyroxine for ovulation induction in infertile women with both PCOS and subclinical hypothyroidism.
- Conditions
- PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries, Subclinical Hypothyroidism, Female Infertility
- Trial name
- NCT06041204
- Testing
- Letrozole 2.5mg, Levothyroxine 25 Mcg (0.025 Mg) Oral Tablet
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Muhamed Ahmed Abdelmoaty Muhamed Alhagrasy
Secondary Hypothyroidism, Hypopituitarism
Phase 4 Study in Secondary Hypothyroidism: Body Weight Adapted Thyroxin Treatment and Triiodothyronine Supplementation
The purpose of this study is to determine whether a body weight adjusted dose of thyroxin is superior to treatment guided by laboratory results of thyroxin hormones in patients with central hypothyroidism.
- Conditions
- Secondary Hypothyroidism, Hypopituitarism, Hyperlipidemias
- Trial name
- NCT00360074
- Testing
- Thyroxin, Triiodothyronine
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- University Hospital Freiburg
Subclinical Hypothyroidism
Discontinuation of Levothyroxine Therapy for Patients With Subclinical Hypothyroidism
The investigators propose the following hypothesis: discontinuation of levothyroxine (LT4) for veterans with subclinical hypothyroidism (SCH) will be feasible, acceptable, and safe and will not negatively affect their Quality of…
- Trial name
- NCT04288115
- Testing
- Levothyroxine
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- VA Office of Research and Development
Hypothyroidism, Hyperthyroidism
Pharmacist Role in Thyroid Disorders
Hypothyroidism (HoT) treatment involves lifelong thyroxine replacement therapy and regular monitoring. The objective of this study was to assess the impact of clinical pharmacist (CP) intervention in managing drug-related…
- Conditions
- Hypothyroidism, Hyperthyroidism, Thyroid Diseases
- Trial name
- NCT06408909
- Testing
- Clinical Pharmacist Intervention Group
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Istanbul University - Cerrahpasa
Recurrent Early Pregnancy Loss, Thyroid Diseases
Thyroxine Therapy for Recurrent Pregnancy Loss in Hypothyroid Women
The goal of this clinical trial is to investigate the influence of thyroxine supplementation on pregnancy outcomes in women with varying levels of Thyroid-Stimulating Hormone (TSH), who have experienced recurrent pregnancy loss…
- Trial name
- NCT06036576
- Testing
- Levothyroxine Pill
- Where
- Iraq
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Al-Kindy College of Medicine
Thyroid Nodule
Levothyroxine Treatment in Thyroid Benign Nodular Goiter
We will study the effect of taking eltroxin at different time, i.e. fasting or postprandial periods. We will also study the effect of levothyroxin treatment in Chinese people
- Trial name
- NCT00552253
- Testing
- Levothyroxin treatment
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- National Taiwan University Hospital
Subclinical Hypothyroidism
Mechanistic Study of Subclinical Hypothyroidism In the Elderly
Subclinical hypothyroidism, defined as an elevated TSH in the setting of normal thyroid hormone levels, is a common diagnosis in the elderly.
- Trial name
- NCT02399475
- Testing
- Levothyroxine, Liothyronine, Thyrotropin-Releasing Hormone
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Pennsylvania
Thyroid Neoplasms, Hypothyroidism
Individual Dosing of Levothyroxine After Thyroidectomy
Recently, Zaborek et al. raised a Poisson regression model for levothyroxine(LT4) dosing scheme to predict individual dose of LT4 after thyroidectomy: daily LT4 dose=e[2.02+0.01(W)-0.0037(A…
- Conditions
- Thyroid Neoplasms, Hypothyroidism, Surgery
- Trial name
- NCT05240911
- Testing
- Levothyroxine Sodium Tablets
- Where
- China
- Volunteers
- 202 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Intraventricular Hemorrhage of Prematurity
Thyroxine Treatment in Premature Infants With Intraventricular Hemorrhage
Brain bleed in premature infants damages the brain and survivors suffer from cerebral palsy (weakness in the extremities), cognitive deficits, and neurobehavioral disorders.
- Trial name
- IVHT4 (NCT03390530)
- Testing
- Thyroxine
- Where
- United States
- Sponsor
- Albert Einstein College of Medicine
Hypothyroidism
Mean Percentage of Levothyroxine Dosage Increase in Patients With Hypothyroidism Started on Enteral Feeding
The study aims to describe the changes in Levothyroxine dosage requirements in patients with hypothyroidism started on enteral feeding, and assess whether giving levothyroxine on empty stomach affects the mean percentage increase…
- Trial name
- NCT02577367
- Testing
- Levothyroxine
- Where
- United States
- Sponsor
- Jocelyne Karam
Subclinical hypothyroïdism
Can Levothyroxine Treatment Reduce the Development of Cardio-metabolic Disorder in Subclinical Hypothyroidism?
2. Aim/ Objectives The aim of this study is to evaluate the clinical, laboratory and echocardiographic findings in children with SCH.
- Trial name
- NCT04178928
- Testing
- Levothyroxine
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Hypothyroidism Primary
Comparison of Two Timings of Levothyroxine Intake in Hypothyroid Patients: A Cross-over Randomized Control Trial
Primary hypothyroidism is a common condition, affecting nearly 10% of the general population. Its treatment is levothyroxine, a synthetic thyroid hormone with a half-life of nearly eight days.
- Trial name
- NCT07900737
- Testing
- Levothyroxine Pill
- Where
- Tunisia
- Volunteers
- 102 people
- Sponsor
- Elyes Kamoun
Hypothyroidism
Combined Therapy With L-Thyroxine and L-Triiodothyronine Compared to L-Thyroxine Alone
The objective of this study was to analyze the features of monotherapy with L-T4 in comparison with combined therapy with L-T4 and L-T3 in patients with primary hypothyroidism.
- Trial name
- NCT00715572
- Testing
- thyroxine, thyroxine and triiodothyronine
- Volunteers
- 36 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Hypothyroidism
Thyroxine Titration Study
The aim of the study is to examine the effects of fine titration of thyroxine dosage on symptoms of hypothyroidism, wellbeing and quality of life.
- Trial name
- NCT00111735
- Testing
- Thyroxine
- Where
- Australia
- Volunteers
- 55 people
- Sponsor
- Sir Charles Gairdner Hospital
Different Regimens in Treatment of Hypothyroidism During Fasting in Ramadan
Comparison Between Variable Time Regimen of Dosing L-Thyroxine for Treatment Hypothyroid Fasting Ramadan
This is a study aiming to report the effect of a variable time regimen of L T4 during Ramadan, as an easier alternative, on adherence and thyroid status after Ramadan compared to standard daily dosing.
- Trial name
- NCT05918497
- Where
- Egypt
- Volunteers
- 89 people
- Sponsor
- Sohag University
Aging, Primary Hypothyroidism
Evaluation of Evening Versus Morning Levothyroxine Intake in Elderly
A study designed to compare evening versus morning levothyroxine intake in the elderly.
- Conditions
- Aging, Primary Hypothyroidism, Interaction Drug Food
- Trial name
- MONIALE (NCT03614988)
- Testing
- Evening Levothyroxine Administration, Morning Levothyroxine Administration
- Where
- Brazil
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Bipolar Disorder
Supraphysiological Doses of Levothyroxine as Adjunctive Therapy in Bipolar Depression
There is growing evidence that thyroid axis dysfunction may contribute to the pathophysiology of bipolar illness. Open-label studies have consistently demonstrated that the behavioral expression of bipolar disorder can be…
- Trial name
- NCT01528839
- Testing
- L-Thyroxine
- Where
- 5 sites in United States, Germany
- Volunteers
- 74 people
- Sponsor
- Charite University, Berlin, Germany
Primary Hypothyroidism.
Desiccated Thyroid Extract and Levothyroxine for Hypothyroidism Treatment
Our hypothesis is that hypothyroid patients on DTE may have a decrease in symptoms, an improvement of cognitive function, and an increase in sense of well-being/ quality of life equivalently compared with L-T4.
- Trial name
- DTE (NCT01739972)
- Testing
- Levothyroxine, Desiccated thyroid extract
- Where
- 2 sites in United States
- Volunteers
- 180 people
- Sponsor
- Walter Reed National Military Medical Center