Clinical trials: Treatment Outcome
Streptococcus Pneumoniae Infection
Effect of Two Versus Three Pneumococcal Conjugate Vaccinations
Two( 2) or three (3) instead of four vaccinations before the age of 6 months with pneumococcal conjugate vaccine are presumed to protect children against invasive pneumococcal disease like meningitis, at least on the short term…
- Trial name
- MNOES (NCT00189020)
- Testing
- PCV7
- Volunteers
- 1,005 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Healthy
A Study to Learn If the Study Medicine Called Carbamazepine Changes How the Body Processes the Other Study Medicine Ibuzatrelvir in Healthy Adults
The purpose of this study is to estimate the effect of carbamazepine, a strong CYP3A4 inducer, on the pharmacokinetics (PK) of ibuzatrelvir in healthy participants.
- Trial name
- NCT06646042
- Testing
- ibuzatrelvir, carbamazepine ER
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
Cardiometabolic Risk Factors, Cognitive Function
The Effect of Tart Cherry (Prunus Cerasus) Concentrate on Physiological and Cognitive Function
A randomized, double blind, counterbalanced, placebo controlled independent groups design to determine the effects of 3 month supplementation with tart cherry concentrate on indices of cardiometabolic health, exercise capacity…
- Conditions
- Cardiometabolic Risk Factors, Cognitive Function, Exercise Capacity
- Trial name
- NCT04021342
- Testing
- Montmorency tart cherry concentrate
- Where
- United Kingdom
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Microbiota, Postoperative Recovery
The Effect of Oral Gan Shuangbi During the Perinatal Period on the Recovery of Intestinal Function After Cesarean Section in Pregnant Women- A Multicenter, Double-blind, Randomized Controlled Clinical Trial
This study aims to evaluate the effect of probiotics 7 days before cesarean section (CS) on postoperative recovery and the change of gut microbiota in pregnant women.
- Trial name
- NCT06347770
- Testing
- Probiotic Blend Oral Tablet
- Where
- 2 sites in China
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- Zhe Li
Inguinal Hernia
Effect of Inguinal Hernia Repair on Isokinetic Muscle Strength
The aim of the present prospective controlled study is to compare the trunk muscle strength, quality of life and neuropathic pain component after Lichtenstein and Kugel procedures.
- Trial name
- NCT02871583
- Testing
- lichtenstein, Kugel
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Konya Meram State Hospital
Nasopharyngeal Carcinoma
Screening Effect of Dual-energy CT Combined With Nasopharyngeal Endoscopy for Screening Nasopharyngeal Carcinoma
All participants will be tested for EBV-related biomarkers, including EBNA1-IgA, VCA-IgA, and BNLF2b total antibody (P85-Ab), and participants with high serologic risk will be selected based on serologic test results, and…
- Trial name
- NCT05884983
- Testing
- participants will undergo dual-energy CT and endoscopy
- Where
- China
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Zhongshan People's Hospital, Guangdong, China
Imagination, Creative Thinking
Stretching the Mind: The Effect of Yoga on Children's Imagination and Creative Thinking
Background: This study was conducted to examine the effect of a yoga-based intervention program on children's imagination and creative thinking. Methods: The study was conducted using a randomized controlled experimental design.
- Trial name
- NCT07798817
- Testing
- Yoga-Based Intervention Program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sinop University
HIV
mHealth Physical Activity Trial for Older HIV-infected Adults (mFIT)
This pilot study will examine the effect of a mobile health text messaging platform linked to a digital physical activity tracker on physical activity among persons living with HIV and frailty.
- Trial name
- NCT03708640
- Testing
- Digital Activity Tracker, Smart Text Messaging, Physical Activity Counseling
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Healthy
Relative Bioavailability DS-1971a Suspension and Tablets and Food Effect on DS-1971a Tablets
This is an open label, randomised, 3 treatment, 3 period crossover study. This study is designed to assess the relative bioavailability of DS 1971a from a tablet formulation and a reconstituted oral suspension and the effect of a…
- Trial name
- NCT02266940
- Testing
- DS-1971a suspension, DS-1971a tablet
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Daiichi Sankyo
Safety, Bioavailability
Relative Bioavailability of Linaprazan for the Test Formulation vs. Reference Formulation
This is a single-center, open-label, randomized, single dose, 3-way crossover study in healthy volunteers designed to evaluate the relative bioavailability of a new oral tablet formulation of linaprazan glurate in comparison to a…
- Conditions
- Safety, Bioavailability, Pharmacokinetics
- Trial name
- BA (NCT05627518)
- Testing
- Linaprazan glurate
- Where
- Slovenia
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Cinclus Pharma Holding AB
Dental Caries
The Effect of Stevia Rebaudiana Extracts on Different Variables Related to Caries: an in Vitro and in Vivo Evaluation.
The aim of the present investigation was to evaluate the effect of stevioside and rebaudioside on several variables related to caries development.
- Trial name
- NCT01757990
- Testing
- Effect of Stevioside and Rebaudioside on plaque pH
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Sassari
Pulmonary Rehabilitation
Effect of Combined IMT and CPAP in Pulmonary Rehabilitation for COPD
Inspiratory muscle training(IMT) was one of the widely used pulmonary rehabilitation method in COPD patients.However, when the respiratory muscles are fatigue without sufficient rest, IMT may increase muscle fatigue and aggravate…
- Trial name
- NCT03919513
- Testing
- inspiratory pressure threshold device
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Treatment
Therapeutic Effect of Immunoadsorption for Patients With Lipoprotein Glomerulopathy
The purpose of this study is to assess the efficacy and safety of immunoadsorption in the treatment of lipoprotein glomerulopathy.
- Trial name
- NCT00302510
- Testing
- immunoadsorption
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Nanjing University School of Medicine
Urinary Incontinence, Fecal Incontinence
Perineal Massage and Pelvic Floor Exercise in the Antenatal Period
This study aimed to determine the effect of perineal massage and pelvic floor exercise in the antenatal period on sexuality and urinary and fecal incontinence in the postpartum period.
- Conditions
- Urinary Incontinence, Fecal Incontinence, Sexual Dysfunction, Sexuality
- Trial name
- NCT05624060
- Testing
- Pelvic Floor Dysfunction Prevention Training, Pelvic Floor Dysfunction Prevention Training and Perineal Massage, Pelvic Floor Dysfunction Prevention Training and Perineal Massage and Pelvic Floor Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Bitlis Eren University
White Spot Lesion
The Effect of ICON Treatment on WPL With Patients After Fixed Orthodontic Appliances
The aim of this study is to determine the effect of ICON on White spot lesions compared to CPP-ACPF plus.
- Trial name
- NCT03391180
- Testing
- ICON Remineralization, CPP-ACPF
- Where
- Saudi Arabia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
Iron Deficiency Anemia, Helicobacter Pylori Infection
The Effect of H. Pylori Infection on Iron Metabolism
The purpose of this study is to determine if Helicobacter pylori (H. pylori) gastritis results in abnormal iron metabolism in patients with iron deficiency anemia (IDA), and to determine if this is due to strain variations in the…
- Trial name
- NCT00202488
- Testing
- H. pylori treatment
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
Pediatric Medication
The Effect of the Virtual Escape Room Method on Pediatric Drug Administration Knowledge, Self-Efficacy, Clinical Comfort, and Anxiety in Nursing Students: A Randomized Controlled Study
Children are particularly vulnerable to injuries resulting from medication errors due to the severity of the illness, the need for high-risk drugs with a narrow therapeutic range, and the frequent use of intravenous infusions.
- Trial name
- Pediatric Drug (NCT06981403)
- Testing
- virtual escape room game-based pediatric medication management education
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Cesarean Section
Aloe Vera on Caesarean Section Wound
Conducting clinical research in line with the literature recommendation, with a method that is low-cost, accessible, easy-to-use, and examined in an evidence-based design related to cesarean section wound, which negatively…
- Trial name
- NCT05223127
- Testing
- Aloe vera
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Absent End-Diastolic Flow Of The Fetal Umbilical Artery
Clinical Significance Of Intermittently Absent End-Diastolic Flow Of The Fetal Umbilical Artery On Perinatal And Neonatal Outcomes Dr. Zeynep Kayaoğlu Yıldırım Dr. Alperen İnce Dr Gökhan Bayanmelek Dr Gökhan Bolluk
Objective: This study aimed to estimate the risk of adverse perinatal outcomes among pregnant patients with intermittently absent (iAEDF) and persistently absent end-diastolic umbilical artery flow (pAEDF).
- Trial name
- NCT06346327
- Where
- Turkey (Türkiye)
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Healthy
A Study in Healthy Women to Test Whether BI 1358894 Influences the Amount of a Contraceptive in the Blood
This study aims to investigate the effect of multiple doses of BI 1358894 on pharmacokinetics of ethinylestradiol (EE) and drospirenone (DRSP) (Yasmin®)
- Trial name
- NCT05934942
- Testing
- Yasmin®, BI 1358894
- Where
- Germany
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
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