Clinical trials: Treatment Outcomes
Metabolic Disease
The Association of Maternal Night-Eating Pattern With Glucose Tolerance During Pregnancy
This study aims to assess the associations of maternal food timing with glucose levels during pregnancy.
- Trial name
- NCT03803345
- Where
- Singapore
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Respiratory Failure, Anxiety
Improving Psychological Outcomes for Acute Respiratory Failure Survivors Using a Self-Management Intervention
A growing number of patients are surviving a stay in the intensive care unit (ICU) but may experience long-lasting psychological problems, but research evaluating such treatment for ICU patients is scant.
- Conditions
- Respiratory Failure, Anxiety, Critical Illness
- Trial name
- SMARA (NCT06341972)
- Testing
- Cognitive behavioral therapy based self-management for anxiety
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Cardiac Rehabilitation
Patient Mobility and Outcomes After Cardiac Surgery
Standards for post-cardiac surgery physical interventions vary between insitutions and there are no published guidelines for national organizations in the U.S.
- Trial name
- NCT03806257
- Testing
- Enhanced Physical Therapy Protocol
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Surgery, Acute Pain
IPACK and Adductor Canal Catheter Patient Outcomes for TKAs?
This study evaluates the addition of the IPACK block to the adductor canal block and catheter in the pain management of total knee arthroplasty.
- Trial name
- NCT03774966
- Testing
- Adductor Canal Block + Catheter & IPACK block, Adductor canal block + catheter
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Maternal Outcomes, Infant Outcomes
Study to Assess Maternal and Infant Outcomes Following Exposure to SPIKEVAX During Pregnancy
The primary objectives of this study are: In infants of women exposed to SPIKEVAX during pregnancy, to assess: If exposure to SPIKEVAX during pregnancy is associated with an increased birth prevalence of major congenital…
- Conditions
- Maternal Outcomes, Infant Outcomes, Pregnancy
- Trial name
- NCT06369272
- Where
- United States
- Volunteers
- 1,192 people, healthy volunteers welcome
- Sponsor
- ModernaTX, Inc.
Total Knee Arthroplasty (TKA)
Total Knee Arthroplasty Biomechanics
In total knee arthroplasty (TKA), the relationship between implant design, soft tissue balance, neuromuscular contributions, and rehabilitation strategies on patient satisfaction and functional outcomes is highly complex and…
- Trial name
- NCT03671954
- Testing
- Home Strengthening Exercises, Standard Physical Therapy, Preoperative Assessments
- Where
- 4 sites in United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Florida
Early Menopause
Singapore Population Research on Integrated exposoMe & Early Menopause
Brief Summary The goal of this observational study is to learn how environmental factors, lifestyle choices, and social conditions affect the timing of menopause in Asian women aged 40-50 years living in Singapore.
- Trial name
- SG-PRIME (NCT07100639)
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Institute for Human Development and Potential (IHDP), Singapore
Preterm Infant, Umbilical Cord Milking
Effect of Intact Umbilical Cord Milking on Neonatal and First Year Neurodevelopmental Outcomes in Very Preterm Infants.
The investigators hypothesise that intact umbilical cord milking (I-UCM) will reduce neonatal morbidity and improve long term neurodevelopmental outcome in very preterm infants.
- Trial name
- Cord-milking (NCT03200301)
- Testing
- Intact Umbilical Cord Milking
- Where
- India
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Jubilee Mission Medical College and Research Institute
Postpartum Depression, Maternal-Fetal Relations
Effect of Listening to Surah Al-Inshirah (The Opening-Up of the Heart) After Cesarean Birth on Postpartum Outcomes
This randomized controlled trial aims to evaluate the effect of listening to the recitation of Surah Al-Inshirah during the early postpartum period after cesarean birth on women's spiritual well-being, depression levels, and…
- Conditions
- Postpartum Depression, Maternal-Fetal Relations, Spirituality
- Trial name
- NCT07354334
- Testing
- Listening to Surah Al-Inshirah
- Where
- Turkey (Türkiye)
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Umbilical Cord Issue, Intrauterine Growth Restriction
Three-dimensional Umbilical Cord Coiling Index
Previous studies have shown that abnormal coiling of the umbilical cord is associated with adverse perinatal outcome. For example, an umbilical cord that is non-coiled increases the chance of fetal morbidity and mortality…
- Conditions
- Umbilical Cord Issue, Intrauterine Growth Restriction, Fetal Distress
- Trial name
- NCT05727241
- Testing
- Ultrasound
- Where
- Israel
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Depression, Anxiety
Efficacy of a Brief Intervention to Improve Sexual and Gender Minorities' Mental Health: Randomized Controlled Trial.
Experiences of violence, from micro to physical aggressions, have a deleterious impact on mental health. According to the Minority Stress Theory, unfavorable social conditions (such as anticipated and experienced discrimination…
- Conditions
- Depression, Anxiety, Psychological Distress, Social Phobia
- Trial name
- ESCREVA-SE (NCT05349877)
- Testing
- Expressive writing, Self-affirmation
- Where
- Brazil
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Anxiety, Pregnancy Related
MoodUP in Improving Psychological Outcomes Among Perinatal Women
Dramatic physiological, psychological, and social changes during the antenatal period may significantly affect a woman's psychosocial and physical conditions, thereby resulting in stress, anxiety, and depressive symptoms.
- Conditions
- Anxiety, Pregnancy Related, Perinatal Depression, Prenatal Stress
- Trial name
- NCT03970057
- Testing
- Internet-based Cognitive Behavioural Therapy, Usual Care
- Where
- Singapore
- Volunteers
- 368 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Health Problems in Pregnancy, Pregnancy Outcomes
Peking University Birth Cohort in Tongzhou
The PKUBC-T is a prospective cohort study carried out in Tongzhou district of Beijing, China. The primary aim of this study is to investigate the short-term and long-term effects of pre-pregnant and prenatal exposure on maternal…
- Conditions
- Health Problems in Pregnancy, Pregnancy Outcomes, Gestational Diabetes, Gestational Hypertension
- Trial name
- PKUBC-T (NCT03814395)
- Testing
- No intervention
- Where
- China
- Volunteers
- 5,426 people, healthy volunteers welcome
- Sponsor
- Peking University
Healthy Subjects
An Exploratory Trial in Hong Kong to Explore the Effect of a New Formula
This is an exploratory study with the aim to gain insight and potentially generate hypotheses on health benefits of feeding with study product.
- Trial name
- NCT06122272
- Testing
- Test Formula, Control Formula
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Danone Nutricia
Geriatric, Aerobic Exercise
Comparing Music-Supported and Traditional Aerobic Training in Geriatric Health Outcomes
The aim of this study is to comparatively evaluate the effects of a music therapy-based aerobic exercise program and traditional aerobic exercise training on cardiopulmonary functions, functional capacity, balance, peripheral…
- Conditions
- Geriatric, Aerobic Exercise, Music Therapy, Physiotherapy and Rehabilitation
- Trial name
- NCT06980311
- Testing
- Aerobic Exercise, Aerobic exercise with music therapy
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Gingival Recession, Mucogingival Surgery
Microsurgical Instruments and Magnification May Enhance Treatment Outcomes Of Laterally Moved, Coronally Advanced Flap in Miller Class III Isolated Recession Defects
The benefits of microsurgical approaches in periodontal therapy have been described. The main focus of this study is to determine if using microsurgical LMCAF technique would improve the outcomes of the therapy for the Miller…
- Trial name
- NCT02281071
- Testing
- laterally moved coronally advanced flap with microsurgical instruments and x2.5 loupe
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Alcohol Use, Unspecified
Study of a Smartphone-Based Alcohol Reduction Program
Prospective, open label, single center clinical study enrolling up to 100 adult participants to evaluate the feasibility, acceptability, and preliminary outcomes of the Pivot Clear smartphone-based alcohol reduction program.
- Trial name
- NCT06401967
- Testing
- Pivot Clear, BACtrack breathalyzer
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pivot Health Technologies Inc.
Anesthesia, Local, Pain
Clinical Trial Comparing Effectiveness of Buffered Versus Unbuffered Local Anesthetic in Children Ages 10-12 Years
Local anesthesia is an integral part of clinical pediatric dental practice, but it has challenges. It can be uncomfortable for children, and the risk of adverse events limits how much is used.
- Trial name
- NCT03562481
- Testing
- 1% Buffered Lidocaine 1:100,000 Epinephrine, 2% Unbuffered Lidocaine 1:100,000 Epinephrine
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Concussion, Brain, Mild Traumatic Brain Injury
The Effects of Environmental Distractions on SCAT6 Outcomes
The purpose of this study is to assess the effects of visual and auditory distractions on SCAT5 scores. The study is designed to identify the effects of about 80 participants completing the SCAT5 in college-aged athletes.
- Trial name
- NCT05886400
- Testing
- SCAT6, Visual/ Auditory Distraction
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Indiana University
Hemophilia A
Phase 3 Study for Efficacy and Safety Outcomes Data in Japanese Patients With Severe Hemophilia A
This Phase III clinical study will evaluate the safety and effectiveness of valoctocogene roxaparvovec in Japanese patients with severe hemophilia A.
- Trial name
- GENEr8-JPN (NCT06224907)
- Testing
- Valoctocogene roxaparvovec
- Where
- 4 sites in Japan
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- BioMarin Pharmaceutical
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