Clinical trials: Treatment Refusal
Vaccination Hesitancy, Pediatric ALL
Effectiveness of an Intervention on Vaccine Hesitancy Among Pediatric Nurses and Pediatricians
The objective of this cluster randomized controlled trial is to assess the effectiveness of a multicomponent intervention designed to improve pediatric nurses' and pediatricians' knowledge, self-efficacy, communication skills…
- Conditions
- Vaccination Hesitancy, Pediatric ALL, Presumptive Communication, Motivational Interviewing
- Trial name
- NCT06489236
- Testing
- Vaccine Confidence: Skills to Promote Vaccination in the Pediatric Consultations
- Where
- Spain
- Volunteers
- 142 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
COVID-19, COVID-19 Pandemic
Community-engaged Optimization of COVID-19 Rapid Evaluation And TEsting Experiences
Throughout the Coronavirus disease (COVID-19) pandemic, rates of COVID-19 have been persistently high in San Diego County's central and southern communities near the United States/Mexico border.
- Trial name
- CO-CREATE-Ex (NCT05894655)
- Testing
- COVID-19 walk-up, on-site testing strategy, Community Health Worker (CHW) leading testing navigation and general preventive care reminders, No-cost self-testing kit vending machines
- Where
- United States
- Volunteers
- 6,527 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Influenza
Effectiveness of SMS Nudging to Increase Coverage of Influenza Vaccination Among the Elderly
The trial will investigate to what extent SMS reminders for influenza vaccination increases coverage of influenza vaccination among elderly from the majority population, and among elderly from immigrant groups with low…
- Trial name
- InfluSMS (NCT06486766)
- Testing
- Norwegian SMS, Polish/Ukrainian SMS
- Volunteers
- 1,000,000 people
- Sponsor
- Norwegian Institute of Public Health
COVID-19, Vaccine Hesitancy
Online Games to Help Canadian and U.S. Adults Identify COVID-19 and Vaccine Misinformation: Three Sequential Randomized Studies
COVID-19 misinformation contributed to vaccine hesitancy and preventable illness. This record covers three sequential randomized studies (conducted in Canada and the United States, November-December 2020) testing whether a brief…
- Conditions
- COVID-19, Vaccine Hesitancy, Health Misinformation, Communication
- Trial name
- NCT07758309
- Testing
- Gamified misinformation refutation quiz, Refutational text (active control)
- Where
- United States
- Volunteers
- 3,637 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Refusal of Treatment
Effects of Italian Law 219/2017 in Pediatric Intensive Care Units
This study aims to investigate pediatric intensive care providers' knowledge, perceptions, and experiences with Law 219/2017 by means of a national multicentric non-interventional cross-sectional study.
- Trial name
- NCT07093047
- Testing
- Questionnaire administration
- Where
- 3 sites in Italy
- Volunteers
- 172 people
- Sponsor
- University of Padova
Measles, Polio
A Tool Kit to Improve Vaccine Confidence in the Philippines
This cluster randomized controlled trial (RCT) aims to evaluate the feasibility and efficacy of an educational toolkit in enhancing measles, mumps, rubella (MMR) and polio vaccine confidence in the Philippines.
- Conditions
- Measles, Polio, Vaccination Hesitancy
- Trial name
- NCT06218368
- Testing
- Educational toolkit on MMR and polio vaccination
- Where
- Philippines
- Volunteers
- 5,400 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Evaluating Impact of PACV on Vaccine Hesitancy Among Parents of Newborns
Impact of PACV Administration on Vaccine Hesitancy
Our objective is to assess the impact of administering the PACV to parents of newborns. We also sought to assess the prevalence of vaccine hesitancy among parents of newborns in Houston, TX and to characterize the demographics of…
- Trial name
- NCT04450940
- Testing
- PACV survey
- Volunteers
- 1,705 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Vaccine Hesitancy, Vaccine Refusal
Improving Vaccine Acceptance Through EHR Integrated Patient- and Provider-Facing Decision Support
The goal of this project is to establish the technical feasibility of a scalable, integrated platform to improve patient informed decision-making and increase vaccine uptake and to evaluate the effectiveness of the integrated…
- Trial name
- NCT06482450
- Testing
- LetsTalkShots (patient-facing CDS), LetsTalkShots (provider-facing CDS), Appointment Reminder Message
- Where
- United States
- Volunteers
- 3,600 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Covid19, Vaccine Refusal
Use of Construal Level Theory to Inform Messaging to Increase Vaccination Against COVID-19
This study aims to increase uptake of the COVID booster vaccine through messaging informed by Construal Level Theory. Patients in the Mass General Brigham (MGB) health system aged 18 and older who are eligible for the COVID…
- Trial name
- NCT04871776
- Testing
- Messaging informed by construal level theory, Usual Care
- Where
- United States
- Volunteers
- 3,671 people
- Sponsor
- Brigham and Women's Hospital
Simulation-based Education, Vaccination Training
High-Fidelity Simulation in Vaccination Training
This study compared the impact of high-fidelity simulation (HFS) versus standart laboratory practice (SLP) on nursing students' knowledge, psychomotor skills, learning satisfaction, and self-confidence within a childhood…
- Conditions
- Simulation-based Education, Vaccination Training, Education Nursing
- Trial name
- NCT07678190
- Testing
- High-Fidelity Simulation, Standard Laboratory Practice
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Vaccination Refusal
A RCT Evaluating an Online Intervention in Increasing Pneumococcal Vaccination Among Older Adults
To evaluate the relative efficacy of an online intervention based on the Trans-theoretical Model delivered by a fully-automated Chatbot with natural language processing functions versus a control in promoting pneumococcal…
- Trial name
- NCT05772117
- Testing
- Chatbot-delivered interventions tailored to stage of changes, Chatbot-delivered standard interventions
- Where
- Hong Kong
- Volunteers
- 374 people
- Sponsor
- Chinese University of Hong Kong
Vaccine Refusal, Covid19
Project 2VIDA! COVID-19 Vaccine Intervention Delivery for Adults in Southern California
The United States (U.S.) is the country with the largest number of infections and deaths due to COVID- 19 and racial/ethnic minorities are disproportionately affected.
- Trial name
- 2VIDA! (NCT05022472)
- Testing
- COVID-19 Individual Awareness and Education., COVID-19 Community Outreach & Health Promotion., COVID-19 Individual Health Education & Linkages to Medical and Supportive Services.
- Where
- 6 sites in United States
- Volunteers
- 1,051 people, healthy volunteers welcome
- Sponsor
- Britt Skaathun
Dengue
Dengue Vaccine Hesitancy and Acceptance in Endemic Regions of Argentina: Impact of Communication Strategies
Among all arboviruses, Dengue (DEN) is the vector borne disease with the highest burden worldwide. Around 390 million infections per year are estimated, of which around 96 million are clinically apparent.
- Trial name
- NCT05213364
- Volunteers
- 1,500 people
- Sponsor
- Fundacion GESICA
Vaccine Hesitancy, Vaccine Refusal
A Survey of Acceptance and Factors Associated With Hesitancy Vaccination in Northeast Brazil
The objective of this study is to investigate vaccination acceptance and identify the reasons why people are not vaccinated. People over 18 years of age who live in neighborhoods with socioeconomic vulnerability and with many…
- Trial name
- NCT06675721
- Testing
- Study Questionnaire
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Centro De Estudos E Pesquisas Em Molestias Infecciosas
Lung Cancer (NSCLC)
Percutaneous Pulsed Electric Field Ablation for Early-Stage NSCLC and Lung Oligometastases: A Safety and Efficacy Study
The goal of this observational study is to evaluate the performances of a percutaneous Pulsed Electrical Field (PEF) ablation to treat patients with primary early-stage lung cancer (NSCLC) or lung oligometastatic Tumors who are…
- Trial name
- NCT07799194
- Testing
- Pulsed Electric Field Ablation
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Energenx Medical LTD.
Endodontic Treatment of Primary Teeth
Endodontic Treatment of Necrotic Primary Teeth With Guedes Pinto Paste: A Randomized Clinical Trial
The maintenance of primary teeth until their exfoliation has been one of the main purposes of Pediatric Dentistry, are they representing the fundamental basis for proper occlusion of the permanent dentition.
- Trial name
- NCT02216942
- Testing
- Endodontic treatment using Vitapex, Endodontic treatment using Guedes Pinto
- Where
- Brazil
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Fausto Medeiros Mendes
Bipolar Disorder
Personal Adherence Evaluation of Medication Use for Adult Bipolar Disorder Patients
This study will attempt to increase understanding of why bipolar disorder patients do or do not take their medications by conducting in-depth interviews with them.
- Trial name
- NCT00763581
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Case Western Reserve University
Vaccine Refusal, COVID-19
Exploring the Effect of Video Interventions on Intentions for Continued COVID-19 Vaccination
While COVID-19 vaccine uptake has generally been high in Canada, with 83.4% of the total population having received the first two doses (i.e., primary series), additional "booster" uptake has been slower, especially among young…
- Trial name
- NCT05808413
- Testing
- Informational Video, Altruistic Video, Individualistic Video
- Where
- Canada
- Volunteers
- 3,567 people, healthy volunteers welcome
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
COVID-19 Vaccines
Improving COVID-19 Vaccine Uptake in Nursing Homes
SARS-CoV-2 vaccine, now being administered to skilled nursing facility (SNF) residents and staff, has highly variable acceptance between facilities.
- Trial name
- NCT04732819
- Testing
- High touch multi-pronged behavioral intervention
- Where
- 4 sites in United States
- Volunteers
- 23,768 people
- Sponsor
- Brown University
HPV Vaccination, Vaccine; Uptake
PREVENT HPV-Related Cancers - BootCamp Translation
This study will serve as one of the first to develop and test the effectiveness of strategies to promote HPV vaccination among diverse rural parents and caregivers of children ages 9-17 years in the Mountain West.
- Conditions
- HPV Vaccination, Vaccine; Uptake, Vaccination; Series Completion
- Trial name
- PREVENT (NCT06290206)
- Testing
- PREVENT - BCT
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Utah