Clinical trials: Treatment Refusal
Vaccine Refusal
Exploring Changes in COVID-19 Vaccination Intentions by Prompting Altruistic Motives Using a Video Intervention
As Canada records over 1,400,000 COVID-19 infections and 26,000 deaths, the need to stop the spread of the virus has become increasingly critical.
- Trial name
- NCT04960228
- Testing
- Altruism Video, COVID-19 Informational Text
- Where
- Canada
- Volunteers
- 2,097 people, healthy volunteers welcome
- Sponsor
- Zeev Rosberger
Health Behavior, Colorectal Cancer
Building Engagement Using Financial Incentives Trial - Colorectal Cancer Screening
The goal of this pilot clinical trial is to determine feasibility and explore whether financial incentives paid to primary care patients for completing colorectal cancer screening increase completion of colorectal cancer…
- Conditions
- Health Behavior, Colorectal Cancer, Influenza, COVID-19
- Trial name
- BENEFIT-C (NCT06124131)
- Testing
- Financial incentive for colorectal cancer screening, Financial incentive for flu shot, Financial incentive for COVID-19 shot
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tulane University
HPV Vaccination, Vaccine; Uptake
PREVENT HPV-Related Cancers - BootCamp Translation
This study will serve as one of the first to develop and test the effectiveness of strategies to promote HPV vaccination among diverse rural parents and caregivers of children ages 9-17 years in the Mountain West.
- Conditions
- HPV Vaccination, Vaccine; Uptake, Vaccination; Series Completion
- Trial name
- PREVENT (NCT06290206)
- Testing
- PREVENT - BCT
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Utah
HIV Infections, Adolescent Development
Tailored Motivational Interviewing Implementation-Effectiveness Trial in Multidisciplinary Adolescent HIV Care Settings
The goal of this study is to test a multi-faceted Tailored Motivational Interviewing Implementation intervention (TMI), based on the Dynamic Adaptation Process (DAP) to scale up an Evidence-based Practice (EBP) in…
- Conditions
- HIV Infections, Adolescent Development, Care Eliciting Behavior, Patient Non-Compliance
- Trial name
- TMI (NCT03681912)
- Testing
- Competency: 12-Item Motivational Interviewing (MI) Coach Rating Scale (CRS), Randomized Guided Development of COPs with an internal facilitator after one year of implementation., CoP development without internal facilitation.
- Where
- United States
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Florida State University
Covid19, Vaccine Refusal
Use of Construal Level Theory to Inform Messaging to Increase Vaccination Against COVID-19
This study aims to increase uptake of the COVID booster vaccine through messaging informed by Construal Level Theory. Patients in the Mass General Brigham (MGB) health system aged 18 and older who are eligible for the COVID…
- Trial name
- NCT04871776
- Testing
- Messaging informed by construal level theory, Usual Care
- Where
- United States
- Volunteers
- 3,671 people
- Sponsor
- Brigham and Women's Hospital
Primary Focal Segmental Glomerulosclerosis
Obinutuzumab in Primary FSGS
The purpose of this study is to evaluate the safety and efficacy of Obinutuzumab in inducing complete or partial remission of proteinuria.
- Trial name
- NCT04983888
- Testing
- Obinutuzumab
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Vaccination Refusal, COVID-19
COVID-19 Vaccine Uptake Trial
The goal of this study is to assess the best COVID-19 vaccine uptake strategy among students, staff and household members that have not been vaccinated.
- Trial name
- NCT05419232
- Testing
- Short Message Service (SMS) + Website Link Strategy, Phone Call with Peer Strategy
- Where
- 8 sites in United States
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Vaccination Refusal, Communication
Emails Promoting COVID-19 Vaccination Among Healthcare Workers
In this evaluation, two versions of emails will be sent to Geisinger employees who have not been vaccinated against COVID-19. A delayed-contact control group will be emailed after a delay of at least two days.
- Trial name
- NCT04728594
- Testing
- Social Proof, Reframing, Scarcity Message
- Where
- United States
- Volunteers
- 9,566 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
End-Stage Heart Failure, Bridge-to-Transplant LVAD Placement (BTT)
Development & Testing of a Decision Aid for LVAD Placement
The goal of this project is to develop a patient-centered decision aid for decision-making about end-stage heart failure treatment.
- Conditions
- End-Stage Heart Failure, Bridge-to-Transplant LVAD Placement (BTT), Destination Therapy LVAD Placement (DT), Refusal of LVAD Placement (Decliners)
- Trial name
- VADDA (NCT02248974)
- Testing
- LVAD Decision Aid
- Where
- 7 sites in United States
- Volunteers
- 98 people
- Sponsor
- Baylor College of Medicine
Vaccine Refusal
Promoting Altruism to Enhance Vaccine Acceptance
Subjects enrolled in this study are eligible for the seasonal influenza vaccine. The purpose of this research study is to figure out if increasing individuals' awareness of the benefits of herd immunity, specifically to the local…
- Trial name
- NCT04568590
- Testing
- educational intervention
- Where
- United States
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Bipolar Disorder
Customized Medication Adherence Enhancement for Treating Adults With Bipolar Disorder
In this study, patients with bipolar disorder who do not take their medications as prescribed will receive specialized education and therapy treatment to determine whether the specialized treatment is effective in helping…
- Trial name
- NCT00763919
- Testing
- Psychoeducation module, Substance abuse module, Improved communication/rapport with provider module
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Case Western Reserve University
Vaccine Hesitancy
Increasing Vaccine Uptake Among Adolescents in the Rural South
The benefits of adolescent vaccines are well known for preventing meningococcal infection and human papillomavirus (HPV)-related pre-cancerous lesions.
- Trial name
- INVEST (NCT04999267)
- Testing
- INVEST
- Where
- 2 sites in United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Duke University
Influenza, Vaccine Hesitancy
Precision Vaccine Promotion in Underserved Populations
Previous studies have shown that low-cost, behavioral nudges through texting can increase influenza vaccination uptake compared to usual care.
- Trial name
- NCT05537441
- Testing
- Text messaging
- Where
- United States
- Volunteers
- 228,831 people
- Sponsor
- University of Southern California
Vaccination Refusal, COVID-19 Pandemic
COVID-19 Messaging for Vaccination
This study will distribute videos of health professionals encouraging Covid-19 vaccination to a large sample of Facebook users, and will test the most effective ways to maximize diffusion of this vaccine-related content to…
- Trial name
- NCT05182554
- Testing
- Doctor Videos, Sharing Videos, Sharing Videos (Influencers)
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Massachusetts Institute of Technology
COVID-19, Vaccine Uptake
Addressing Vaccine Hesitancy and Increasing COVID-19 Vaccine Uptake Among African American Young Adults in the South
The study staff will conduct a hybrid type 1 effectiveness implementation 2-arm trail with 360 Black young adults from Alabama, Georgia, and North Carolina.
- Trial name
- NCT05490329
- Testing
- Tough Talks COVID
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Florida State University
COVID-19
COVID-19 Vaccine Hesitancy Counseling Intervention for Pharmacists
The goal of this clinical trial is to test if virtual facilitation (e.g., video coaching) increases rural pharmacists' ability to implement COVID-19 vaccine hesitancy counseling when compared to a "standard" implementation…
- Trial name
- NCT05926544
- Testing
- Standard implementation webinar and online training, Virtual facilitation
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of North Carolina, Chapel Hill
COVID-19
COVID-19 Vaccine Hesitancy Counseling Intervention for Pharmacists: A Stepped-Wedge Trial
The goal of this clinical trial is to test if virtual facilitation (e.g., video coaching) increases rural pharmacists' ability to implement COVID-19 vaccine hesitancy counseling when compared to a "standard" implementation…
- Trial name
- NCT06547814
- Testing
- Standard implementation webinar and online training, Virtual facilitation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of North Carolina, Chapel Hill