Clinical trials: Tremor Essential
Essential Tremor
Alternating Current Stimulation for Essential Tremor
Movement disorders are common neurological disorders, characterized by either excess or paucity of movements. Essential tremor (ET) is one of the most common of these disorders, defined as chronic, rhythmic involuntary movements…
- Trial name
- NCT04509349
- Testing
- transcranial Altering Current Stimulation
- Volunteers
- 30 people
- Sponsor
- University of Calgary
Parkinsons Disease, Essential Tremor
Battery-preserving Stimulation Patterns for Deep Brain Stimulation
The purpose of this research study is to test effectiveness of different deep brain stimulation (DBS) stimulation patterns on symptoms that may also improve the life of the battery.
- Trial name
- NCT02569021
- Testing
- Biphasic DBS stimulation, Unified Parkinson's Disease Rating Scale, Tremor Rating Scale
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Florida
Essential Tremor, Parkinson's Disease
Evaluation of the Infinity Deep Brain Stimulation Electrode Screening Mode Tool
The objective of this clinical investigation is to characterize the clinical performance of Abbott's Clinician Programmer Electrode Screening Mode tool (InformityTM tool) in programming InfinityTM deep brain stimulation (DBS)…
- Trial name
- EVIDENT (NCT03794661)
- Testing
- Clinician programmer electrode screening mode tool
- Where
- 3 sites in United States
- Volunteers
- 8 people
- Sponsor
- Abbott Medical Devices
Essential Tremor
Adaptive Portable Essential Tremor Monitor
The purpose of this study is to evaluate the utility of a portable motion sensor-based system designed to monitor essential tremor (ET) to better prescribe therapy to minimize symptoms and expand care for ET patients.
- Trial name
- NCT01602042
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Great Lakes NeuroTechnologies Inc.
Essential Tremor
Experimental Therapeutics in Essential Tremor Using Cerebellar Transcranial Direct Current Stimulation
The purpose of this study is to determine whether transcranial cathodal direct current stimulation (tDCS) delivered over the cerebellum can improve essential tremor.
- Trial name
- ELECTRE2 (NCT02052271)
- Testing
- Cathodal cerebellar transcranial direct current active stimulation
- Where
- France
- Volunteers
- 16 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Essential Tremor
Open Label Study for the Use of Low Intensity Focused Ultrasound for Essential Tremor
This open-label pilot study will evaluate the safety, tolerability, feasibility, and preliminary efficacy of repeated low-intensity focused ultrasound pulsation (LIFUP) targeting the ventral intermediate nucleus (Vim) of the…
- Trial name
- NCT07599592
- Testing
- Low Intensity Focused Ultrasound (LIFU)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, Los Angeles
Movement Disorders, Essential Tremor
ExAblate Transcranial MRgFUS for the Management of Treatment-Refractory Movement Disorders
The proposed study is to evaluate the effectiveness of ExAblate Transcranial MRgFUS as a tool for creating a unilateral lesion in the Vim thalamus or the globus pallidus (GPi) in patients with treatment-refractory symptoms of…
- Conditions
- Movement Disorders, Essential Tremor, Holmes Tremor, Parkinson's Disease
- Trial name
- NCT02252380
- Testing
- Transcranial ExAblate System
- Where
- 2 sites in Canada
- Volunteers
- 10 people
- Sponsor
- InSightec
Essential Tremor
Efficacy of Levetiracetam in Essential Tremor
Essential tremor poses one of the greatest therapeutic challenges to neurologists. This study will examine the effectiveness of the drug, levetiracetam or keppra, for the treatment of essential tremor.
- Trial name
- NCT00620165
- Testing
- levetiracetam
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Southern California Institute for Research and Education
Parkinsonian Syndrome, Parkinson Disease(PD)
A Study to Evaluate the Diagnostic Efficacy of DaTSCAN™ Ioflupane (123I) Injection in Single Photon Emission Computed Tomography (SPECT) for the Diagnosis of Parkinsonian Syndrome (PS) in Chinese Patients
This is a multicenter, open-label, non-controlled, non-randomized, phase 3 clinical study to compare the SPECT findings after a single IV administration of DaTSCAN™ ioflupane (123I) injection for patients with a clinical…
- Conditions
- Parkinsonian Syndrome, Parkinson Disease(PD), Multiple System Atrophy (MSA), Progressive Supranuclear Palsy (PSP)
- Trial name
- NCT04193527
- Testing
- DaTSCAN™ Ioflupane (123I) Injection
- Where
- 10 sites in China
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
Parkinson Disease (PD), Essential Tremor
Modulate Tremor Severity With Low-intensity Focused Ultrasound Stimulation Targeting the Deep Nucleus of Patients With Refractory Hand Tremor.
The study plans to recruit 12 patients with Parkinsonian tremor, essential tremor, or dystonic tremor. After receiving NaviFUS-ctbTUS stimulation, the improvement in their tremor will be recorded.
- Conditions
- Parkinson Disease (PD), Essential Tremor, Dystonic Tremor, Continuous Theta Burst Stimulation Transcranial Focused Ultrasound
- Trial name
- NCT07172295
- Testing
- Accelerated NaviFUS-ctbFUS stimulation
- Where
- Taiwan
- Volunteers
- 12 people
- Sponsor
- National Taiwan University Hospital
Essential Tremor, Healthy Individuals
Impact of Sensory Electrical Stimulation on Sensation and Tremor
The purpose of this study is to understand the acute, short-term and long-term impact of transcutaneous and/or percutaneous electrical stimulation with afferent-specific electrical stimulation (asES) on proprioception and fine…
- Trial name
- NCT06428526
- Testing
- Continuous stimulation strategy, Closed-loop stimulation strategy
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Upper Limb Essential Tremor (UL ET)
Study of BOTOX Injections to Assess Change in Disease Symptoms in Adult Participants With Upper Limb Essential Tremor
Upper limb essential tremor (UL ET) is a movement disorder characterized by postural and/or kinetic tremor. It can cause difficulty with everyday tasks such as writing, pouring, and eating, and patients also experience associated…
- Trial name
- NCT05216250
- Testing
- BOTOX
- Where
- 40 sites in United States, Canada
- Volunteers
- 174 people
- Sponsor
- AbbVie
Essential Tremor
Nonlinear Absorber in Essential Tremor Treatment
The goal of this study is to develop a non linear absorber for patients with essential tremor (ET). It 's an extern passive medical device which should improve patients tremor.
- Trial name
- TREM-AB (NCT06397391)
- Testing
- TREM-AB
- Where
- France
- Volunteers
- 5 people
- Sponsor
- Hospices Civils de Lyon
Tremor
Electrophysiological Study of the Effects of Limb Cooling on Essential Tremor
To determine the effects of upper limb forearm cooling on Essential Tremor upper limb tremor using a more practical method of limb cooling through a forearm cold pack.
- Trial name
- NCT01093027
- Testing
- 15 - 30, 30 - 15
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Essential Tremor, Dystonic Tremor
VIM DBS Respiratory Modulation: N-of-1 Trial
Research from our group has demonstrated modulation of PEFR in patients with STN and PAG stimulation. However, the effect of VIM (motor thalamus) stimulation remains to be investigated.
- Trial name
- NCT05381688
- Testing
- VIM DBS
- Sponsor
- University of Oxford
Essential Tremor, Transcranial Direct Current Stimulation
Transcranial Direct Current Stimulation of the Motor Cortex in Essential Tremor
The current research is aimed at using Transcranial Direct Current Stimulation (tDCS) as complementary therapeutic tool in the treatment of essential tremor. Patients will be randomized into two groups (tDCS-cathode vs.
- Trial name
- NCT03952117
- Testing
- transcranial direct current stimulation
- Where
- Lebanon
- Volunteers
- 40 people
- Sponsor
- Lebanese American University
Essential Tremor
Clinical Trial Characterizing the Bioavailability of 1-Octanol in Adults With Ethanol-responsive Essential Tremor
OVERVIEW Essential tremor (ET) is a common movement disorder affecting 0.4% of the general population and up to 14% of people 65 years and older.
- Trial name
- NCT00102596
- Testing
- 1-Octanol
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Essential Tremor, Continuous Theta Burst Stimulation
Tolerability and Efficacy of Continuous Theta-burst Stimulation for Essential Tremor: A Randomized Study.
Essential tremor (ET) is one of the most common movement disorders in adults. The prevalence rate among the elderly over 65 years old is about 4.6%.
- Trial name
- NCT06314139
- Testing
- continuous theta-burst stimulation (cTBS)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- West China Hospital
Essential Tremor
Transcranial Ultrasound Therapy of Essential Tremor
Context. Essential tremor (ET) is a common disease, disabling in severe forms and resistant to drug treatment. In patients with severe ET, invasive neurosurgical technique such as deep brain stimulation of the Ventral…
- Trial name
- ULTRABRAINTher (NCT04074031)
- Testing
- Transcranial Ultrasound Therapy (Exablate® 4000 Type 1.1)
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Essential Tremor
Repetitive Transcranial Magnetic Stimulation in Essential Tremors Patients
The aim of the study is to investigate the Effect of Repetitive Transcranial Magnetic Stimulation on Essential Tremors.
- Trial name
- NCT05157321
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Al-Azhar University