Clinical trials: Triggering Ovulation
Infertility
Luteal Phase Support With Daily Administration of Gonadotropin-releasing Hormone Agonist Compared to Progesterone/Estradiol in IVF/ICSI Cycles With Ovulation Triggering With GnRH-a
Purpose: To determine the efficacy and safety of daily injections of gonadotropin-releasing hormone agonist in comparison with the standard strategy of supporting the luteal phase in protocols with gonadotropin-releasing hormone…
- Trial name
- NCT05143723
- Testing
- Gonadotropin-releasing hormone agonist
- Where
- Russia
- Volunteers
- 102 people
- Sponsor
- Kuban State Medical University
IVF Cycle, Ovarian Stimulation
Efficacy and Safety of Medication Used to Stimulate Ovulation
Individuals undergoing In Vitro Fertilization must undergo controlled ovarian hyperstimulation (COH) to produce enough quality eggs for fertility treatment.
- Conditions
- IVF Cycle, Ovarian Stimulation, Egg Retrieval, Pregnancy
- Trial name
- NCT02715336
- Testing
- Ovulation induction with hCG and Lupron (GnRH agonist)
- Where
- Canada
- Volunteers
- 666 people, healthy volunteers welcome
- Sponsor
- Create Fertility Center
Low Dose, Progesterone
Role of Low Dose Injectable Progesterone in Triggering Ovulation
The aim of this study is to evaluate the role of low dose injectable progesterone in triggering ovulation.
- Conditions
- Low Dose, Progesterone, Triggering Ovulation
- Trial name
- NCT06928844
- Testing
- Progesterone
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- The General Authority for Teaching Hospitals and Institutes
Infertility
Observation of the Response to Ovulation Triggering on the Day of Intrauterine Insemination and Correlation Between Progesterone Level and Pregnancy Rate (OVUL-IIU)
Intrauterine inseminations (IUI) are a commonly used technique in assisted reproductive technology (ART) to help women conceive, whether within a couple or as single individuals.
- Trial name
- OVUL-IIU (NCT07038616)
- Where
- France
- Volunteers
- 158 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Infertility
Comparison Between Recombinant Versus Urinary hCG for Ovulation Induction in High Responders
The purpose of this study is to compare the clinical outcomes of recombinant human chorionic gonadotrophin (rHCG) and urinary HCG (uHCG) in patients undergoing IVF cycles.
- Trial name
- NCT00415766
- Testing
- rHCG 250ug, uHCG 5000 IU, uHCG 7500 IU
- Where
- Greece
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Eugonia
Poor Response to Ovulation Induction
Ovarian Response in Oocyte Donors Triggered With GnRH Agonists
The use of agonist of GnRH (aGnRH) trigger to avoid ovarian hyperstimulation syndrome is nowadays widely used. The action of the aGnRH in the hypophysis triggers an LH and FSH surge, which mimicks the natural surge that occurs in…
- Trial name
- NCT05109403
- Where
- Spain
- Volunteers
- 224 people
- Sponsor
- Clínica EUGIN
Infertility (IVF Patients)
Triggering Ovulation in Normo-responders Using a Modified Dual Trigger Protocol or HCG Trigger
The aim of this randomized controlled study is to compare the efficacy of a modified dual trigger protocol [a single bolos of HCG combined with two successive doses of a GnRH agonist ] with HCG [a single bolos administered 36…
- Trial name
- NCT07569302
- Testing
- Modified dual trigger, HCG
- Where
- Egypt
- Volunteers
- 196 people
- Sponsor
- Bedaya Hospital
Infertility
HCG Levels After Ovulation Triggering as Predictors of ICSI Outcome
This study aimed to assess the correlation between HCG levels after ovulation triggering and ICSI outcomes, affected by HCG formulation and dose
- Trial name
- NCT05969834
- Testing
- uHCG, rHCG, uHCG and GnRHa
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Embryo Transfer
Triggering Ovulation at Follicle Size Smaller or Larger Than 17mm in a Modified Natural Cycle
The rise in frozen embryo transfer (FET) cycles within assisted reproductive technology (ART) has sparked the need to refine endometrial preparation protocols.
- Trial name
- 17FET (NCT07088952)
- Testing
- Trigger at smaller folicular size
- Where
- Spain
- Volunteers
- 572 people
- Sponsor
- Vida Recoletas Sevilla
Infertility
Ovulation Triggering 2 vs 3 Follicles
Poor responders in in-vitro fertilization (IVF) cycles represent a major challenge for fertility specialists. Although poor responders tend to have sub-optimal fertility treatment outcomes, many of these patients wish to attempt…
- Trial name
- NCT06290921
- Testing
- Ovulation triggering
- Where
- Canada
- Volunteers
- 405 people
- Sponsor
- Clinique Ovo
Fertilization, Fertilization in Vitro
BEst Size for Ovulation Triggering in Poseidon 4 Patients (BEST 4 Study)
This observational clinical study aims to determine the optimal timing of ovulation triggering in women aged 35 and above with poor ovarian reserve.
- Trial name
- BEST (NCT06433518)
- Testing
- Ovulation Trigger Timing Based on Leading Follicle Size in POSEIDON Group 4 IVF Patients
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Centrum Clinic IVF Center
Spontaneous Triggering of Ovulation vs. Administration of Human Chorionic Gonadotropin in Patients Undergoing IUI
HCG Versus Spontaneous LH in Intrauterine Insemination (IUI ) Cycles
We recently reported the superiority of the natural cycle to a natural cycle controlled by the administration of human chorionic gonadotropin (hCG) for planning the frozen-thawed embryo transfer cycles, demonstrating a probable…
- Trial name
- NCT01414673
- Testing
- HCG
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Embryonic Development, Pregnancy
Pregnancy Rates in IVF After Ovulation Triggering With Recombinant or Urinary Human Chorionic Gonadotrophin (HCG)
To access whether the ovulation triggering with rec-HCG instead urinary-HCG has any impact on the blastulation rate and pregnancy rate of patients undergoing IVF treatment
- Conditions
- Embryonic Development, Pregnancy, VEGF
- Trial name
- NCT00954265
- Testing
- 10000 IU urinary HCG, 250 mcg recombinant HCG
- Where
- Belgium
- Volunteers
- 130 people
- Sponsor
- Universitair Ziekenhuis Brussel
Pregnancy, Pregnancy Loss
Luteal Supplementation With Rec-LH After GnRH-agonist Triggering in In Vitro (IVF)
Our aim is to access whether we can achieve equivalent pregnancy rates by the addition of six doses of luteal support with recLH after agonist triggering for IVF cycles in the absence of OHSS.
- Trial name
- NCT00954811
- Testing
- 300IU rec-LH, progesterone 600mg
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Universitair Ziekenhuis Brussel
ICSI, IVF
Dual Trigger VS HCG Trigger for Final Oocyte Maturation in Normal Responders
To compare the embryological and reproductive outcomes of dual trigger versus conventional hCG trigger for final oocyte maturation in normal responder patients undergoing ICSI cycles.
- Conditions
- ICSI, IVF, Normal Responders, Infertility Assisted Reproductive Technology
- Trial name
- DT-HCG-IVF (NCT07861399)
- Testing
- Dual trigger (human chorionic gonadotropin plus GnRH-agonist), hCG trigger
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Al-Azhar University
Infertility
Frozen-thawed Embryo Transfer in a Natural Cycle: hCG Triggering Versus LH Home Test
The primary aim of this study is to find out if ovulation triggered with hCG provides any additional benefit in comparison to spontaneous LH surge measured with the LH surge home test when transferring frozen-thawed embryo in a…
- Trial name
- NCT03115320
- Testing
- Human chorionic gonadotropin, Home ovulation test
- Where
- Finland
- Volunteers
- 62 people
- Sponsor
- Tampere University Hospital
OHSS (Ovarian Hyperstimulation)
Triggering of Final Oocyte Maturation With GnRHa (Buserelin) in GnRH Antagonist Cycles
The purpose of this study is to possibly further improve the clinical outcome and explore the incidence of OHSS in patients, who have final oocyte maturation with GnRHa (Buserelin) in GnRH antagonist IVF/ICSI cycles
- Trial name
- NCT00627406
- Testing
- Buserelin and Pregnyl, Pregnyl
- Where
- Denmark
- Volunteers
- 384 people
- Sponsor
- Regionshospitalet Viborg, Skive