Clinical trials: Tuberculous Pleurisy
Pleural Effusion, Pleurisy
Yield of Cryoprobe vs Flexible Forceps Pleural Biopsy
This is a prospective study to assess the yield of pleural biopsy obtained with the routine flexible thoracoscopic biopsy forceps versus that obtained with a flexible cryoprobe during semirigid thoracoscopy
- Conditions
- Pleural Effusion, Pleurisy, Tuberculosis, Metastatic Malignancy
- Trial name
- COFFEE (NCT02500277)
- Testing
- Cryoprobe pleural biopsy first, Flexible forceps biopsy first
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Pleural Effusion, Tuberculosis, Pleural
A Prospective Observational Study on the Role of Transthoracic Ultrasound in Differentiating Tuberculous From Malignant Pleural Effusion
Primary Endpoint To assess the prevalence and diagnostic performance of pre-determined echographic features in predicting the diagnosis of TBE from MPE.
- Conditions
- Pleural Effusion, Tuberculosis, Pleural, Malignant Pleural Effusion
- Trial name
- TUS-TBE (NCT05935696)
- Where
- Malaysia
- Volunteers
- 100 people
- Sponsor
- Sarawak General Hospital
Tuberculosis, Pleural Effusion
Continuous Positive Airway Pressure on Tuberculosis Pleural Effusion
Tuberculosis (TB) remains as an important public health problem worldwide. Pleural tuberculosis is the most prevalent form of extrapulmonary presentation in immunocompetent patients.
- Trial name
- NCT00560521
- Testing
- CPAP
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Tuberculosis, Pleural
MTB cfDNA Levels in TBP
Tuberculous pleuritis (TBP) is the most common manifestation of extrapulmonary TB. Its diagnosis is challenging due to the low sensitivity of mycobacterial culture from the pleural fluid and the need for invasive pleural biopsy.
- Trial name
- MYDNITE (NCT05397730)
- Testing
- Mycobacterium tuberculosis (MTB) cell-free DNA (cf-DNA)
- Where
- Hong Kong
- Volunteers
- 329 people
- Sponsor
- Chinese University of Hong Kong
Tuberculosis, Pleural, Pleural Biopsy
Diagnostic Utility of Mycobacterium Tuberculosis Cell-free DNA in Hong Kong
Tuberculosis (TB) is an endemic infectious disease in Hong Kong and a global health threat. Tuberculous pleuritis (TBP) is the most common form of extrapulmonary tuberculosis in China.
- Trial name
- MYDNITE-3 (NCT06646237)
- Where
- Hong Kong
- Volunteers
- 350 people
- Sponsor
- Chinese University of Hong Kong
Tuberculous Pleurisy
Drainage of Tuberculous Pleural Effusions
Tuberculous (TB) pleurisy can cause clinical symptoms and pleural fibrosis with resultant residual pleural thickening (RPT). Therapeutic thoracentesis or initial complete drainage in addition to anti-TB drugs have been tried to…
- Trial name
- NCT00524147
- Testing
- Pigtail drainage
- Where
- Taiwan
- Volunteers
- 64 people
- Sponsor
- Taipei Medical University Hospital
Tuberculosis, Pleural
Diagnostic Utility of Mycobacterium Tuberculosis Cell-free DNA
Tuberculosis (TB) is one of the major global health threats and is the second leading infectious cause of death after COVID-19 in 2022.
- Trial name
- MYDNITE-2 (NCT06439810)
- Testing
- Mycobacterium tuberculosis (MTB) cell-free DNA (cfDNA)
- Where
- Hong Kong
- Volunteers
- 400 people
- Sponsor
- Chinese University of Hong Kong
Tuberculosis, Tuberculous Pleurisy
Comparison the Level of CTGF Protein and Related Cytokine in Pleural Effusion
Connective tissue growth factor (CTGF) is known to be a fibrogenic cytokine, it could be expressed in various fibrosis diseases. But, recent research showed that CTGF also be considered to be a tumor suppressive gene.
- Conditions
- Tuberculosis, Tuberculous Pleurisy, Malignant Pleural Effusion, Empyema
- Trial name
- NCT00313066
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Taichung Veterans General Hospital
Pleural Effusion, Tuberculosis, Pleural
TBP Survey Among Respiratory Physicians
Tuberculosis is a major infectious disease with a high mortality burden in the Asia-Pacific region and worldwide. Among various types of extrapulmonary tuberculosis, tuberculous pleuritis (TBP) is amongst the most common…
- Trial name
- NCT06390969
- Testing
- Survey
- Where
- Hong Kong
- Volunteers
- 418 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Pleural Effusion, Pleural Diseases
Rigid Thoracoscopy Versus CT-Guided Pleural Needle Biopsy
The aim of this study is to compare the rigid thoracoscopy with CT-guided pleural needle biopsy by the diagnostic efficacy and safety in patients with pleural effusion.
- Trial name
- NCT00720954
- Testing
- Ct-guided pleural needle biopsy, Thoracoscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people
- Sponsor
- Eskisehir Osmangazi University
Tuberculous Pleurisy
Corticosteroids in the Treatment of Tuberculous Pleurisy
Tuberculous pleurisy is associated with inflammation and fibrosis. Adjunctive corticosteroids are used for tuberculous pleurisy because their anti-inflammatory effect is thought to minimise pleural reactivity and thereby reduce…
- Trial name
- NCT00338793
- Testing
- prednisolone
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Guangxi Medical University
Tuberculosis, Pleural Effusion
Reproducibility of Computed Tomography
Thus, the aim of this study was to evaluate the reproducibility of the Computed Tomograph scan three-dimensional reconstruction method for the measurement of the TB pleural effusion volume in clinically stable patients.
- Trial name
- NCT01616264
- Volunteers
- 20 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Tuberculosis, Pleural
E-Nose: Diagnostic Tool for Pleural TB
The purpose of this study is to determine the diagnostic utility of the device 'Electronic Nose' for Pleural TB, which is a Extra pulmonary TB form, compared with pleural biopsy, the current gold standard.
- Trial name
- NCT02765087
- Testing
- Medical History, E-Nose, Chest CT
- Where
- Venezuela
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad Central de Venezuela
Pleural Diseases
Outcome of Patients Undiagnosed Under Medical Thoracoscopy
Medical thoracoscopy (MT) under local anaesthetic and mild sedation, an established method in the diagnosis of pleural diseases.
- Trial name
- NCT01356979
- Testing
- Medical thoracoscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 355 people
- Sponsor
- Eskisehir Osmangazi University
To Investigate Diagnostic Aid of the Inflammation and Apoptosis-associated Markers and Apoptosis Pattern of PE Neutrophil for Tuberculous Pleurisy
Evaluating the Diagnostic Validity of Inflammation-associated Markers for Tuberculous Pleurisy
1. To investigate the difference of PE inflammation/apoptosis-associated markers between TB pleurisy and non-TB pleurisy 2. To investigate the difference of neutrophil apoptosis in exudative PE between TB pleurisy and non-TB…
- Trial name
- NCT01685099
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital