Clinical trials: Type 2 Diabetes, completed
Type2 Diabetes Mellitus
Multicenter Study to Evaluate the Effect of BTI320 on Glycemic Control in Type 2 Diabetes
The objective of the current study is to investigate the efficacy and safety of BTI320 compared to placebo in addition to metformin and/or sulfonylureas on glycemic control over 12 weeks in subjects with type 2 diabetes mellitus.
- Trial name
- NCT03655535
- Testing
- BTI320
- Where
- 4 sites in United States
- Volunteers
- 66 people
- Sponsor
- Boston Therapeutics
Obesity
A Study of Safety and Efficacy of Topiramate in Male Patients With Abdominal Obesity
The purposes of this study are to compare the effects of Topiramate and placebo on abdominal visceral fat accumulation at 6 months and to evaluate the safety of Topiramate for up to 12 months of continued treatment in male…
- Trial name
- NCT00231608
- Testing
- topiramate
- Volunteers
- 68 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Diabetic Polyneuropathy, Diabetic Foot
The Effect of Mini Trampoline Exercise Program on Diabetic Foot Care Behavior and Polyneuropathy
This study was planned to examine the effect of home-based mini trampoline exercise program on diabetic foot care behavior and diabetic polyneuropathy in Type 2 diabetes patients.
- Conditions
- Diabetic Polyneuropathy, Diabetic Foot, Type 2 Diabetes
- Trial name
- NCT05668325
- Testing
- Mini trampoline exercise group, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Type 2 Diabetes Mellitus, Bone Fractures
Microarchitecture, Bone Strength and Fracture Risk in Type 2 Diabetes
This multicenter, prospective, observational cohort study will assess bone differences in women and men with type 2 diabetes mellitus (T2DM) with and without fragility fractures.
- Trial name
- DiabOS (NCT02551315)
- Where
- 5 sites in Switzerland
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Type 2 Diabetes Mellitus
Study Examining Exenatide Long-Acting Release in Subjects With Type 2 Diabetes
Exenatide LAR is a long-acting release formulation of exenatide, which is a twice-daily dosage form currently under investigation as a potential treatment for people with type 2 diabetes mellitus.
- Trial name
- NCT00103935
- Testing
- Exenatide LAR
- Where
- 7 sites in United States
- Volunteers
- 45 people
- Sponsor
- AstraZeneca
Diabetes Mellitus Type 2 in Obese
VLCD & Adjuvant Exercise Effect in Overweight Diabetic Men
Sarcopenia is defined as the incremental age-related loss of skeletal muscle in humans which generally begins from forty years old.
- Trial name
- VLCDeXDM (NCT04957589)
- Testing
- Very Low Calorie Diet, High Intensity Interval Training
- Where
- United Kingdom
- Volunteers
- 21 people
- Sponsor
- University of Nottingham
Type 2 Diabetes Mellitus
Optimal Dietary Fat Pattern to Prevent Cardiovascular Disease Among Type 2 Diabetes
Cardiovascular complications are the leading cause of death among type 2 diabetic patients. Postprandial triglyceride-rich lipoproteins (ppTRLs) are atherogenic.
- Trial name
- NCT00467168
- Testing
- Diet
- Where
- 2 sites in China
- Volunteers
- 30 people
- Sponsor
- Sun Yat-sen University
Type 2 Diabetes
Time Course of the Blood Pressure Lowering Effect of Liraglutide Therapy in Type 2 Diabetes
Background: Preclinical blood pressure (BP) data from studies of hypoglycemic effects of liraglutide treatment (the LEAD program), revealed a significant antihypertensive potential.
- Trial name
- Liratime (NCT01499108)
- Testing
- liraglutide
- Where
- Denmark
- Volunteers
- 32 people
- Sponsor
- Peter Rossing
Type 2 Diabetes, Overweight
Weight Loss Study for People With Type 2 Diabetes
The purpose of this study is to determine whether the Weight Watchers program modified for use by people with Type 2 diabetes results in more improvements in blood glucose control relative to a control group receiving standard…
- Conditions
- Type 2 Diabetes, Overweight, Obesity
- Trial name
- T2D (NCT01601574)
- Testing
- Weight Watchers modified program, Standard Care group
- Where
- 15 sites in United States
- Volunteers
- 563 people
- Sponsor
- Medical University of South Carolina
Healthy Participants, Type 2 Diabetes
A Study to Investigate Multiple Ascending Doses of AZD5004 in Healthy Japanese Participants and Participants With Type 2 Diabetes Mellitus
This Phase I study will gather important information on the safety, tolerability, pharmacokinetics and pharmacodynamics of AZD5004 in both healthy Japanese participants and Japanese participants with T2DM.
- Trial name
- NCT06703658
- Testing
- AZD5004(Part A), AZD5004(Part B)
- Where
- Japan
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Type 2 Diabetes
The INDORSE Study: Inhibition of Dipeptidyl Peptidase IV: Outcomes on Renal Sodium Excretion
Background: Dedicated renal hemodynamic and renal function studies are lacking for DPP-4 inhibitors in patients with Type 2 diabetes; accordingly little is known regarding the mechanisms mediating the renal effects of DPP-4…
- Trial name
- INDORSE (NCT02406443)
- Testing
- Sitaglitpin
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- University Health Network, Toronto
Diabetes Mellitus, Type 2, Sleep
Diabetes Education and A1c Study
Sleep problems are associated with poor blood glucose control, but current diabetes self-management programs do not include sleep education.
- Trial name
- DEA1c (NCT04806685)
- Testing
- Sleep education, Diet only
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Michigan State University
Diabetes Mellitus, Type 2, Hypertension
Inspiratory Muscle Strength Training in Adults With Type 2 Diabetes
This clinical research study will investigate the effects of 6 weeks of inspiratory muscle strength training on metabolic and cardiovascular outcomes in adults with recent-onset type 2 diabetes.
- Trial name
- DIT (NCT05643768)
- Testing
- Inspiratory muscle strength training (IMST)
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Arizona
LVM, Type 2 Diabetic Patients With IHD
Pioglitazone Regress Left Ventricular Mass in Type 2 Diabetes With Ischeamia Heart Disease
Cardiovascular complications account for the highest mortality in type 2 diabetic patients, mainly due to ischeamia heart disease (IHD).
- Conditions
- LVM, Type 2 Diabetic Patients With IHD, Endothelial Function
- Trial name
- NCT01947790
- Testing
- pioglitazone group, Metformin group
- Where
- 2 sites in China
- Volunteers
- 120 people
- Sponsor
- Xiang Guang-da
Diabetes Type 2, Metabolic Syndrome
Regulating Efficacy and Wellness in Diabetes
The propose of the study is to test the hypothesis that an eight week program consisting of walking exercise and social cognitive theory based group workshops will increase physical activity adherence six months later in older…
- Trial name
- REWinD (NCT01790724)
- Testing
- Walking exercise
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Pediatric Obesity
Family-based Lifestyle Intervention Program and Carotenoid Supplementation for Children With Obesity
This is a pilot study of children between the ages of 8 to 11 years of age who are obese and participating in an intense family based intervention with a family-focused multi-component lifestyle intervention.
- Trial name
- NCT02060279
- Testing
- Lifestyle intervention and carotenoid supplements
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Nemours Children's Clinic
Diabetes Mellitus, Type 2, Implant Complication
Posterior Narrow Diameter Implants in Hyperglycemic and Normo-glycemic Patients
The aim of the present study was to compare the initial healing and long term performance of narrow diameter implants in patients with uncontrolled Diabetes mellitus type 2 (T2DM) and healthy individuals.
- Trial name
- NCT04630691
- Testing
- Implantation
- Volunteers
- 35 people
- Sponsor
- University of Witten/Herdecke
Diabetes Mellitus Type 2 in Obese, Type 2 Diabetes Mellitus With Features of Insulin Resistance
Percutaneous Electric Neurostimulation of Dermatome T7 Improves Glycemic Profile in Obese and Typo 2 Diabetic Patients
Percutaneous neurostimulation of dermatome T7 increases Insulin segregation by the apancreas and improves glycemic profile in diabetic patients
- Trial name
- NCT02122874
- Testing
- Percutaneous Neurostimulation (PENS) of dermatome T7, 1200 Kcal diet
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Hospital General Universitario Elche
Smoking
Brief Intervention to Promote Smoking Cessation in DM Smokers
The study is a randomized controlled trial (RCT) on a tailored smoking cessation intervention targeted type 2 diabetic patients who smoke (DM intervention). The objectives are: 1.
- Trial name
- NCT02875782
- Testing
- Smoking cessation and DM specific component intervention, Control group
- Volunteers
- 557 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Hypertension, Diabetes Mellitus, Type 2
INV-144 Versus Losartan in Hypertension and Type 2 Diabetes Mellitus Patients With Macroalbuminuria
A randomized, double-blind, active control trial to determine the safety, efficacy and pharmacokinetics of INV-144 versus losartan potassium plus placebo in subjects with hypertension and Type 2 diabetes mellitus with nephropathy…
- Trial name
- NCT01398423
- Testing
- Active Control, INV-144
- Where
- 19 sites in United States
- Volunteers
- 88 people
- Sponsor
- InVasc Therapeutics, Inc.
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