Clinical trials: Type 2 Diabetes Mellitus With Complication
Diabetic Foot Ulcers
Effectiveness of Buerger Allen Exercise Among Type 2 Diabetes Mellitus Patients With Foot Ulcer
This study was conducted to determine the effect of Buerger Allen exercises on lower extremity perfusion and wound healing in patients with foot ulcer type 2 diabetes.
- Trial name
- NCT05747872
- Testing
- Buerger Allen Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Gazi University
Diabetic Nephropathy
The Effects of Bindarit in Diabetic Nephropathy
The purpose of this study is to determine whether bindarit is effective to reduce albuminuria, compared to placebo, in nephropathic patients treated with irbesartan, as a background therapy.
- Trial name
- NCT01109212
- Testing
- Bindarit
- Where
- 6 sites in Italy, Slovenia
- Volunteers
- 100 people
- Sponsor
- Aziende Chimiche Riunite Angelini Francesco S.p.A
Diabetic Nephropathy Type 2
Extracorporeal Low-intensity Shockwave in Diabetic Nephropathy
In the current study, we use extracorporeal low-intensity shockwave therapy (ESWT) to treat on patients with type 2 diabetes in stage 3-4 chronic kidney disease and see whether it can improve the proteinuria, renal function, and…
- Trial name
- NCT03445247
- Testing
- Extracorporeal low-intensity shockwave
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital
Type 2 Diabetes Mellitus
Effects of Short-term Intensive Insulin Therapy on Long-term Complications in Type 2 Diabetes
Short-term intensive insulin therapy (SIIT) is able to reverse β cell dysfunction and induce glycemic remission in patients with newly diagnosed type 2 diabetes.
- Trial name
- NCT03909555
- Testing
- Complications assessment
- Where
- China
- Volunteers
- 777 people
- Sponsor
- Sun Yat-sen University
Diabetic Kidney Disease, Diabetic Nephropathies
Patient-Derived Stem Cell Therapy for Diabetic Kidney Disease
The Researchers will assess the safety, tolerability, dosing effect, and early signals of efficacy of intra-arterially delivered autologous (from self) adipose (fat) tissue-derived mesenchymal stem/stromal cells (MSC) in patients…
- Conditions
- Diabetic Kidney Disease, Diabetic Nephropathies, Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1
- Trial name
- NCT03840343
- Testing
- Autologous adipose-derived mesenchymal stem/stromal cells (MSC) Lower Dose, Autologous adipose-derived mesenchymal stem/stromal cells (MSC) Higher Dose
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Mayo Clinic
Type 2 Diabetes
Renal Effects of DPP-4 Inhibitor Linagliptin in Type 2 Diabetes
The aim of this study is to detail the (mechanisms underlying the) actions of the DPP-4 inhibitor linagliptin on the renal system in patients with type 2 diabetes mellitus.
- Trial name
- RENALIS (NCT02106104)
- Testing
- Linagliptin 5 mg QD (N=24), Glimepiride 1 mg QD (N=24)
- Where
- Netherlands
- Volunteers
- 48 people
- Sponsor
- Amsterdam UMC, location VUmc
Diabetic Nephropathies
Relation Between Plasma Apelin Level and Diabetic Nephropathy in Type 2 Diabetes Patients.
Diabetic nephropathy (DN) is the commonest cause of chronic kidney disease, and proteinuria isn't determent factor for the end stage renal disease in diabetics.
- Trial name
- NCT04380584
- Testing
- plasma Apelin level
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Diabetic Nephropathies
Safety and Efficacy of Different Oral Doses of BAY94-8862 in Subjects With Type 2 Diabetes Mellitus and the Clinical Diagnosis of Diabetic Nephropathy
To assess a new drug, BAY94-8862 given orally at different doses, to evaluate whether it was safe and can help the well being of patients with type 2 diabetes and diabetic nephropathy.
- Trial name
- ARTS-DN (NCT01874431)
- Testing
- Finerenone (BAY94-8862)
- Where
- 147 sites in United States, Australia and 21 more
- Volunteers
- 823 people
- Sponsor
- Bayer
Microalbuminuria, Proteinuria
To Assess the Effects of Valsartan on Albuminuria/Proteinuria in Hypertensive Patients With Type 2 Diabetes Mellitus
This study is designed to assess the efficacy of the different dosage forms of Valsartan[80, 160, and 320 mg] in reducing microalbuminuria/proteinuria in hypertensive patients with type 2 diabetes.
- Trial name
- NCT00550095
- Testing
- valsartan
- Where
- Egypt
- Volunteers
- 509 people
- Sponsor
- Novartis
Diabetic Neuropathy Peripheral
Evaluation and Treatment for Diabetic Peripheral Neuropathy
This study aims: To compare conventional diabetic neuropathy screening techniques with user-friendly technological equipment; To evaluate the effects of the combined application of laser and therapeutic ultrasound in the…
- Trial name
- NCT07317284
- Testing
- Active Comparator
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo
Diabetic Nephropathy Type 2
Effect of Exercise Therapy on Type II Diabetic Neuropathic Patients
The goal of this Randomized control trial (clinical trial) is to learn about the effect of Exercise therapy on Type II Diabetic Neuropathic Patient in Pakistan ,40-70 year's old patient, will be refer by physicians.
- Trial name
- NCT06332378
- Testing
- Experimental group 1 :Ball training, Experimental group 2 :Frenkel Exercises, Control Group
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Dr. Sobia Hasan
Diabetes Mellitus, Type 2, Kidney Failure, Chronic
Study of the Use of Niaspan for Treatment of Dyslipidemia in Diabetic Nephropathy
The primary purpose of this study is to test the effectiveness and tolerability of Niaspan® to improve the levels of blood fats ("good" and "bad" cholesterol and triglyceride levels) in people who have kidney damage due to…
- Conditions
- Diabetes Mellitus, Type 2, Kidney Failure, Chronic, Hyperlipidemia
- Trial name
- NCT00108485
- Testing
- Extended release niacin
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Miami
Type 2 Diabetes, Chronic Kidney Disease 5D
A Multi-centre Trial to Assess the Efficacy and Safety of the Omnipod 5 System in People With Type 2 Diabetes Undergoing Haemodialysis
Diabetes is the leading cause of kidney failure in the UK. Many people with diabetes and advanced kidney failure inject themselves with insulin and do finger-prick blood glucose tests.
- Trial name
- AID-HD (NCT07422532)
- Testing
- Omnipod 5, Insulin injections
- Where
- 4 sites in United Kingdom
- Volunteers
- 84 people
- Sponsor
- Imperial College London
Diabetes Mellitus, Type 2, Gestational Diabetes
Hormonal and Inflammatory Changes During Pregnancy in Women With Glucose Metabolic Disorders.
The first aim of this study is to describe maternal hormonal and inflammatory changes during pregnancy in women that differ metabolically (limited to women with type 2 diabetes, gestational diabetes and/or overweight).
- Conditions
- Diabetes Mellitus, Type 2, Gestational Diabetes, Overweight and Obesity, Pregnancy in Diabetic
- Trial name
- HI-MET (NCT04617405)
- Testing
- No interventions
- Where
- 3 sites in Denmark
- Volunteers
- 300 people
- Sponsor
- University of Aarhus
Diabetic Kidney Disease
Decision Impact Trial of KidneyIntelX
The current trial is designed to evaluate how the results of KidneyIntelX test impacts on the clinical management of type 2 diabetes patients identified as increased risk for rapid kidney function decline within 5-years.
- Trial name
- NCT04791358
- Testing
- KidneyIntelX
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- Renalytix AI, Inc.
Diabetes Mellitus, Type 2, Impaired Renal Function
Dapagliflozin Treatment in Type 2 Diabetes
Open label, mechanistic, single-arm study to evaluate the natriuretic effect of 2 weeks dapagliflozin treatment in T2DM patients with impaired renal function.
- Trial name
- NCT04620590
- Testing
- Dapagliflozin 10 MG [Farxiga]
- Where
- 2 sites in United States, Canada
- Volunteers
- 17 people
- Sponsor
- Emerald Clinical Inc.
Type II Diabetes
Impact of the Rapid Normalization of Chronic Hyperglycemia and the Practice of Moderate Physical Activity on the "Receptor Activator of Nuclear Factor-kappa B Ligand / Osteoprotégérine (RANKL / OPG) System in Patients Living With Type II Diabetes
The rapid normalization of hyperglycemia can cause a neuropathy called Diabetes Treatment-Induced Neuropathy (NITD). This phenomenon induces the presence of hyper vascularization and inflammation in contact with the nerve ends.
- Trial name
- RANKL-GLYC (NCT04893135)
- Testing
- pratice physical activity
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Sud Francilien
Type 2 Diabetes
Improving Risk Factors for Diabetes Complications in Primary Care
The purpose of this study is to test an intervention in primary care clinics to improve three risk factors for diabetes complications: glucose control, blood pressure and cholesterol.
- Trial name
- NCT00482768
- Testing
- Practice Facilitation
- Where
- United States
- Volunteers
- 2,493 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Type 2 Diabetes, Early Nephropathy
Renal and Systemic Effects of NCX4016 in Patients With Type 2 Diabetes and Early Nephropathy
Aspirin is commonly used for treatment of painful and inflammatory diseases and in the prevention of the cardiovascular disease. A major drawback of aspirin treatment is the well recognized gastrointestinal toxicity.
- Trial name
- NCT00157508
- Testing
- nitroaspirin
- Where
- Italy
- Volunteers
- 13 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Diabetes Mellitus, Type 2, Catheterization, Peripheral
Incidence of Complications of Peripheral Venous Access in the Type 2 Diabetic Population
Diabetes Mellitus type 2 (T2DM) is one of the most frequent metabolic diseases worldwide. It is expected that in 2035 around 600 million people will suffer from the disease.
- Conditions
- Diabetes Mellitus, Type 2, Catheterization, Peripheral, Upper Extremity Deep Vein Thrombosis, Catheter-Related Infections
- Trial name
- NCT04499638
- Testing
- Peripheral vascular catheters
- Where
- Spain
- Volunteers
- 350 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute