Clinical trials: Type 2 Diabetes Patients
Type 2 Diabetes Mellitus With Complication
Canagliflozin on Liver Inflammation Damage in Type 2 Diabetes Patients With Nonalcoholic Fatty Liver Disease
Type 2 diabetes mellitus (T2DM) is always accompanied with nonalcoholic fatty liver disease (NAFLD).This prospective, randomized controlled intervention study was designed to reveal the potential clinical application and…
- Trial name
- NCT05422092
- Testing
- Canagliflozin, Pioglitazone
- Volunteers
- 80 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
T2DM (Type 2 Diabetes Mellitus), Low-level Laser Therapy
Effect of Low-level Laser Therapy on Type II Controlled Diabetic Patients After Dental Implant Insertion
This study aimed therefore to evaluate bone density (BD) and OPG levels in the peri-implant crevicular fluid (PICF) in lased controlled type II Diabetes Mellitus (T2DM) patients versus non-lased T2DM patients.
- Conditions
- T2DM (Type 2 Diabetes Mellitus), Low-level Laser Therapy, Bone Density Increased
- Trial name
- NCT05279911
- Testing
- low-level laser therapy (LLLT)
- Where
- 5 sites in Egypt
- Volunteers
- 40 people
- Sponsor
- Sinai University
Patients
Drug Interaction Study Between Dorzagliatin and Empagliflozin
This is a Phase 1, open-label, sequential, multiple-dose, drug interaction study of glucokinase activator dorzagliatin and empagliflozin in subjects with T2DM.
- Trial name
- NCT03790787
- Testing
- Empagliflozin, Dorzagliatin
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Hua Medicine Limited
Type 2 Diabetes
24 Hour Plasma Glucose Profiles Comparing Lispro Mix 75/25 vs. Glargine
The purpose of this study is to determine if twice-daily Lispro low mixture (75/25) will result in lower post prandial blood glucose readings versus once-daily glargine plus oral diabetic medications.
- Trial name
- NCT00551538
- Testing
- Lispro mix 75/25, Glargine
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Eli Lilly and Company
Diabetes
Comparing the Effect of Structured Care Versus Usual Care in Type 2 Diabetes Patients Across the Asia Pacific Region
In this demonstration project (Asia Pacific JADE and DIAMOND Program, AP-JD in short) supported by the Asia Diabetes Foundation (ADF), patients will be recruited from different sites across Asia, with each site recruiting at…
- Trial name
- AP-JD (NCT01631084)
- Testing
- JADE, DIAMOND
- Where
- Hong Kong
- Volunteers
- 20,834 people
- Sponsor
- Asia Diabetes Foundation
Diabetes, Diabetes Mellitus, Type 2
Effect of Repaglinide and Metformin Combination Tablet or Rosiglitazone and Metformin in Fixed Dose Combination on Blood Glucose Control in Patients With Type 2 Diabetes
This trial is conducted in the United States of America (USA). This trial compares the changes in HbA1c after 26 weeks of repaglinide and metformin fixed dose combination tablet given as twice daily versus three times daily…
- Trial name
- NCT00399711
- Testing
- repaglinide and metformin combination tablet, rosiglitazone and metformin combination tablet
- Where
- 103 sites in United States, Puerto Rico
- Volunteers
- 560 people
- Sponsor
- Novo Nordisk A/S
Diabetes Type 2 on Insulin, Hypoglycemia (Diabetic)
Comparing Glycemic Outcomes of Carbohydrate Counting vs. Fixed Mealtime Insulin Dosing in Hospitalized Patients With Hyperglycemia
The study compares two current practices for calculating insulin dose for admitted patients: flexible fixed mealtime dosing based on percent of meal eaten and carbohydrate counting based on amount of carbohydrates eaten.
- Conditions
- Diabetes Type 2 on Insulin, Hypoglycemia (Diabetic), Hyperglycemia Due to Type 2 Diabetes Mellitus
- Trial name
- MEND (NCT07808398)
- Testing
- Carbohydrate-counting-based prandial rapid-acting insulin dosing, Flexible fixed mealtime rapid-acting insulin dosing based on percentage of meal consumed
- Volunteers
- 500 people
- Sponsor
- Mayo Clinic
Diabetes Mellitus, Type 2
Effects of Exercise Therapy on Ventricular and Endothelial Function in Patients After Coronary Artery Bypass Surgery
The purpose of this study was (1) to compare the peak exercise capacity and left ventricular diastolic function between patients with and without diabetes and (2) to investigate the interrelation among peak oxygen consumption…
- Trial name
- NCT01990638
- Testing
- exercise capacity test
- Where
- Taiwan
- Volunteers
- 51 people
- Sponsor
- National Taiwan University Hospital
Diabetes (Insulin-requiring, Type 1 or Type 2), Pediatric Diabetes
A Novel Miniature Equine-Assisted Diabetes Education Program for Youth: Evaluating the Diabetes Equine Empowerment Program (DEEP).
The Diabetes \& Equine Empowerment Program (DEEP) is a research study evaluating a novel diabetes education program that combines hands-on interactions with miniature horses and evidence-based diabetes self-management education…
- Conditions
- Diabetes (Insulin-requiring, Type 1 or Type 2), Pediatric Diabetes, Diabetes (DM)
- Trial name
- DEEP (NCT07822555)
- Testing
- Diabetes & Equine Empowerment Program (DEEP)
- Volunteers
- 50 people
- Sponsor
- Nemours Children's Clinic
Diabetes
Observational Registry for Basal Insulin Treatment Study (ORBIT)
The scientific use of basal insulin is of great help to individuals and the government. However, there are few studies to investigate the real world use, effect, safety and influence factors of basal insulin in China.
- Trial name
- NCT01859598
- Where
- 2 sites in China
- Volunteers
- 19,894 people
- Sponsor
- The George Institute for Global Health, China
Diabetes Mellitus, Type 2
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Rising Oral Doses of BI 44847 in Female and Male Patients With Type 2 Diabetes
Study to investigate the safety, tolerability, pharmacokinetics, and pharmacodynamics of BI 44847 following administration of multiple rising oral doses over 8 days in patients with type 2 diabetes.
- Trial name
- NCT02211963
- Testing
- BI 44847
- Volunteers
- 48 people
- Sponsor
- Boehringer Ingelheim
Type I Diabetes
Pharmacokinetic and Early Efficacy of OPT101 in Patients With Type 1 Diabetes Mellitus
This study will examine the safety of three times weekly SC injections of OPT101 at each of three dose levels over two weeks as well as one year of treatment with SC OPT101 or placebo to match at a single dose level.
- Trial name
- NCT06964087
- Testing
- OPT101
- Where
- 5 sites in United States
- Volunteers
- 72 people
- Sponsor
- Op-T LLC
Type 2 Diabetes
Efficacy of Acarbose on Intestinal Microbiome and Incretins of Type 2 Diabetes
This study is aimed to investigate the effect of acarbose on intestinal microbiome and incretins, therefore to explore the new pathways or new targets to treat type 2 diabetes.
- Trial name
- NCT01758471
- Testing
- Glipizide, Acarbose
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Diabetes Mellitus, Type 2, NAFLD
Screening of Liver Fibrosis Using Blood Tests in Patients With Type 2 Diabetes Mellitus
Non-Alcoholic Fatty Liver Disease (NAFLD) and Non-Alcoholic SteatoHepatitis (NASH), are a frequent complication of type 2 diabetes and obesity.
- Conditions
- Diabetes Mellitus, Type 2, NAFLD, NASH
- Trial name
- L-FibroT2DM (NCT04232293)
- Testing
- Blood tests
- Where
- 2 sites in France
- Volunteers
- 722 people
- Sponsor
- Nantes University Hospital
Diabetes Mellitus, Type 2
A Study of the Effect of LY2189265 on Blood Pressure and Heart Rate in Type 2 Diabetes
The purpose of this study is to assess the effects of 2 doses of LY2189265 on blood pressure and heart rate using 24-hour ambulatory blood pressure monitoring (ABPM), in participants with type 2 diabetes mellitus treated with…
- Trial name
- NCT01149421
- Testing
- LY2189265
- Where
- 76 sites in United States, Argentina and 6 more
- Volunteers
- 755 people
- Sponsor
- Eli Lilly and Company
Diabetes Mellitus Type 2
Comparative Effectiveness of Cardiovascular Outcomes in New Users of SGLT-2 Inhibitors
CVD-REAL is a multinational, observational cohort study in patients with type 2 diabetes mellitus evaluating the comparative effectiveness of initiating treatment with a sodium-glucose co-transporter-2 (SGLT-2) inhibitor versus…
- Trial name
- CVD-REAL (NCT02993614)
- Where
- 17 sites in United States, Australia and 15 more
- Volunteers
- 99,999 people
- Sponsor
- AstraZeneca
Diabetes, Dyslipidemia
The Effects of Hypolipemic and Antidiabetic Treatment on Cytokines
The study is planned to show whether combined hypolipemic and antidiabetic therapy with various daily dosages influence the fasting plasma glucose, insulin sensitivity and proinflammatory cytokines in diabetic and dyslipidemic…
- Conditions
- Diabetes, Dyslipidemia, Inflammation, Cytokines
- Trial name
- MSF (NCT01101204)
- Testing
- Metformin 1000mg, simvastatin 10mg and fenofibrate 100mg
- Where
- Poland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Medical University of Silesia
Cardiovascular Benefits of Zingiber Officinale Roscoe in Patients With Type 2 Diabetes Mellitus Before and After 6 Weeks of add-on Therapy
The Cardiovascular Effects of Ginger (Zingiber Officinale) in Patients With Type II Diabetes Mellitus
The aim of the study was the evaluation of cardiovascular benefits of Zingiber officinale Roscoe in patients with type 2 diabetes mellitus before and after 6 weeks of add-on therapy.
- Trial name
- GINOFF1 (NCT04222738)
- Testing
- GINOFF1
- Where
- Cameroon
- Volunteers
- 21 people
- Sponsor
- Yaounde Central Hospital
Type 2 Diabetes Mellitus
Effects of Ginger Supplementation on NF-KB in Peripheral Blood Mononuclear Cells in Type 2 Diabetes Mellitus
This study evaluates the effect of ginger on NF-KB level in Peripheral Blood Mononuclear Cells in type 2 diabetic patients. Half of patients will receive ginger, while the other half will receive placebo.
- Trial name
- NCT02666807
- Testing
- Ginger
- Volunteers
- 50 people
- Sponsor
- Tehran University of Medical Sciences
Type 1 Diabetes
Monocyte Function and Inflammation in Type 1 Diabetes and Its Modulation
Type I diabetes (T1DM) is associated with an increased risk of vascular complications. While the precise mechanism(s) by which diabetes accelerates atherosclerosis has not been elucidated, several lines of evidence point to the…
- Trial name
- NCT00441844
- Testing
- Simvastatin
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, Davis
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