Clinical trials: Type One Diabetes Mellitus
Diabetes Mellitus Type 2
Bridging the Gap by Transitional Care
The purpose of the study is to evaluate patient adherence with discharge diabetes medications up to 120 days following pharmacist counseling during hospital stay about diabetes self management
- Trial name
- NCT01330121
- Testing
- Pharmacist Counseling
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Cook County Health
Diabetes, Diabetes Mellitus, Type 1
Efficacy and Safety of Insulin Aspart in Subjects With Type 1 or Type 2 Diabetes
This trial is conducted in Asia. The aim of this trial is to compare the efficacy of postprandial plasma glucose of two treatment regimens in Chinese subjects.
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- NCT00593255
- Testing
- soluble human insulin, insulin aspart, insulin NPH
- Where
- 5 sites in China
- Volunteers
- 220 people
- Sponsor
- Novo Nordisk A/S
Diabetes Mellitus, Type 2
Safety and Tolerability of Pioglitazone-Azilsartan in Subjects With Type 2 Diabetes
The purpose of this study is to determine the safety and tolerability of pioglitazone-azilsartan, once daily (QD), in patients with type 2 diabetes mellitus.
- Trial name
- NCT01124656
- Testing
- Pioglitazone-Azilsartan
- Volunteers
- 26 people
- Sponsor
- Takeda
Obesity, Type 2 Diabetes
Hyperbaric Oxygen Therapy and Insulin Resistance (HOTAIR2) - Effect of One HBO Session.
Obesity is an epidemic in Western society and is the biggest risk factor for insulin resistance and type 2 diabetes. The investigators have recently shown that exposure to hyperbaric oxygen (HBO) leads to an increase insulin…
- Trial name
- HOTAIR2 (NCT02009813)
- Testing
- Hyperbaric Oxygen Therapy
- Where
- Australia
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Adelaide
Type One Diabetes Mellitus
Evaluation of a Mobile Application Designed to Support Type 1 Diabetic Patients in Adjusting Their Insulin Doses.
Title: Evaluating a Mobile Application for Insulin Management in Iraqi Type 1 Diabetes Patients. The goal of this clinical trial is to determine whether a mobile health application can improve insulin management and blood sugar…
- Trial name
- NCT07234500
- Testing
- mHealth Mobile Application, Standard Care (in control arm)
- Where
- Iraq
- Volunteers
- 50 people
- Sponsor
- University of Baghdad
Weight Loss
Oral VK2735 for Weight Management Phase 3 (SUNRISE 1)
This study is one of two planned Phase 3 studies to support the weight management indication for VK2735 Oral in obese (BMI ≥ 30 kg/m2) or overweight (BMI ≥ 27kg/m2) adults with at least one weight-related comorbidity without type…
- Trial name
- NCT07868835
- Testing
- VK2735
- Volunteers
- 560 people
- Sponsor
- Viking Therapeutics, Inc.
Obesity, Morbid, Type 2 Diabetes Mellitus (T2DM)
Comparative Outcomes of One-Anastomosis Gastric Bypass and Roux-en-Y Gastric Bypass As Revisional Procedures Following Failed Restrictive Bariatric Surgery
Study Description This prospective, multicenter study aims to compare the outcomes of One-Anastomosis Gastric Bypass (OAGB) and Roux-en-Y Gastric Bypass (RYGB) as revisional procedures for patients experiencing insufficient…
- Conditions
- Obesity, Morbid, Type 2 Diabetes Mellitus (T2DM), Hypertension, Dyslipidemia
- Trial name
- COBRA stady (NCT06794892)
- Where
- Italy
- Volunteers
- 328 people
- Sponsor
- Azienda Sanitaria Locale Napoli 2 Nord
Arterial Hypertension, Diabetes Mellitus
Azilsartan Medoxomil in Hypertensive pAtients With Stable Ischemic Heart Disease and DiabEtes MEllitus.
One-center, observational, non-interventional, prospective study of the efficacy of azilsartan medoxomil in patients with arterial hypertension associated with stable ischemic heart disease and type 2 diabetes mellitus.
- Conditions
- Arterial Hypertension, Diabetes Mellitus, Stable Chronic Angina
- Trial name
- AcADEME (NCT03539627)
- Testing
- Azilsartan Medoxomil 40 MG Oral Tablet [Edarbi]
- Where
- Russia
- Volunteers
- 184 people
- Sponsor
- Research Institute for Complex Problems of Cardiovascular Diseases, Russia
Chronic Kidney Disease, Diabetic Kidney Disease
A Trial to Learn More About How BAY2327949 Works and How Safe it is in Patients Whose Kidneys Are Damaged Due to High Blood Sugar Levels or High Blood Pressures, and With a Further Disease of the Heart or the Blood Vessels.
In people with type 2 diabetes (T2D), the body makes insulin, but cannot use it well. This results in high blood sugar levels causing damage to the blood vessels inside the kidneys.
- Trial name
- ASSESS-CKD (NCT04661917)
- Testing
- BAY2327949
- Where
- 36 sites in Austria, Denmark and 5 more
- Sponsor
- Bayer
Diabetes, Diabetes Mellitus, Type 1
Evaluation of Biomarker Expression in Diabetic and Healthy Subjects Over a One Year Period
This study is conducted in the United States of America (USA). The aim of this study is to assess longitudinal variation of immune biomarkers in subjects with type 1 diabetes (T1D), type 2 diabetes (T2D) and healthy, non-diabetic…
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Healthy
- Trial name
- NCT01900834
- Testing
- No treatment given
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Diabetes Type 2
Time Course of the Antiproteinuric and Blood Pressure Lowering Effects After Initiation of Renin Inhibition With Aliskiren in Type 2 Diabetes
This study will evaluate the time-course of the antiproteinuric effect of renin inhibition with Aliskiren in patients with Type 2 diabetes suffering from incipient and/or established nephropathy.
- Trial name
- NCT00461136
- Testing
- Aliskiren
- Where
- Denmark
- Volunteers
- 18 people
- Sponsor
- Novartis
Type 1 Diabetes
The Effect of Omega-3 Supplementation on Nerve Structure and Function in Type 1 Diabetes
Nerves are made of different fats including omega-3s and omega-6s; however, dietary intakes of omega-6s are very high and omega-3 intakes are very low.
- Trial name
- NCT02034266
- Testing
- Omega-3 supplementation
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Eduardo Ng
Diabetes Mellitus, Type 2
Comparison of a Basal Plus One Insulin Regimen With a Biphasic Insulin Regimen in Type 2 Diabetes Patients
The primary objective is to demonstrate the non-inferiority at six months of a basal plus one insulin regimen (Lantus plus one injection of Apidra) compared with a biphasic insulin regimen (NovoMix 30) at controlling glycosylated…
- Trial name
- LanScape (NCT00965549)
- Testing
- INSULIN GLARGINE (HOE901), Insulin aspart, Insulin Glulisine
- Where
- 74 sites in Australia, United Kingdom
- Volunteers
- 463 people
- Sponsor
- Sanofi
Incretin Hormones Plasma Levels, Gastric Bypass Surgery
A Comparative Study Between Effect Of Mini-gastric Bypass and Single Anastmosis Sleeve Jujenal Bypass On Levels Of GLP-1, GIP, PYY, Insulin Resistance and Type II DM Resolution
The aim of this work is to compare the outcome of Single Anastomosis Sleeve Jejunal Bypass (SASJ) with One Anastomosis Gastric Bypass (OAGB) as regards effect on levels of GLP-1 mainly, PYY and GIP and subsequent effect on…
- Trial name
- NCT07475143
- Testing
- Single anastomosis sleeve jejunal bypass, One anastomosis gastric bypass
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Diabetes Mellitus, Type 1, Diabetes type1
Repeat BCG Vaccinations For The Treatment Of Pediatric Type 1 Diabetes
The purpose of this study is to investigate if repeat bacillus Calmette-Guérin (BCG) vaccinations can confer a beneficial immune and metabolic effect on pediatric Type 1 diabetes.
- Conditions
- Diabetes Mellitus, Type 1, Diabetes type1, Autoimmune Diabetes
- Trial name
- NCT05180591
- Testing
- Bacillus Calmette-Guérin, Saline Injection
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Massachusetts General Hospital
Diabetes Mellitus, Type 1, Pediatric ALL
Intensive Versus Standard One Year Monitoring on Glycaemic Control After Initiating CSII in Children With DT1. DEEP Study
More than half of type 1 diabetes (DT1) children are under CSII (Continuous Subcutaneous Insulin Infusion). Several studies showed that despite a patients' follow-up mostly by hospital-based paediatricians, there are still some…
- Trial name
- DEEP (NCT04100070)
- Testing
- Monitoring of the patients
- Where
- France
- Volunteers
- 320 people
- Sponsor
- ISIS Diabete Service
Diabetes Mellitus, Type 1 Diabetes
Repeat BCG Vaccinations for the Treatment of New Onset Type 1 Diabetes in Children Age 8-<18 Years
The purpose of this study is to investigate if repeat bacillus Calmette-Guérin (BCG) vaccinations can confer a beneficial immune and metabolic effect in new onset pediatric Type 1 diabetes.
- Conditions
- Diabetes Mellitus, Type 1 Diabetes, Diabetes type1, Autoimmune Diabetes
- Trial name
- NCT05866536
- Testing
- Bacillus Calmette-Guérin, Saline Injection
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Obesity and Type 2 Diabetes, NAFLD - Non-Alcoholic Fatty Liver Disease
OneSTOP (One-Stop Telehealth Obesity Program) for Multidisciplinary Weight Management and Related Comorbidities
The goal of this clinical trial is to learn if the use of a care model including teleconsults and the EMPOWER app can induce clinically significant weight loss and metabolic improvements in obese adults with diabetes and…
- Conditions
- Obesity and Type 2 Diabetes, NAFLD - Non-Alcoholic Fatty Liver Disease, Hypertension, Dyslipidaemia
- Trial name
- OneSTOP (NCT06890169)
- Testing
- OneSTOP program, Standard of care weight management program
- Where
- Singapore
- Volunteers
- 120 people
- Sponsor
- Changi General Hospital
Large-for-gestational-age Neonates, Glycemic Variability
Diabetes Type One in Pregnancy and Continuos Glucose Monitoring
Type I diabetes mellitus (T1DM) affects about 0.1-0.2% of all pregnancies. T1DM in pregnancy increases the risk of maternal and neonatal complications.
- Conditions
- Large-for-gestational-age Neonates, Glycemic Variability, Hypoglycemia, Pregnancy Outcomes
- Trial name
- DIP1/CRO (NCT04997460)
- Where
- Croatia
- Volunteers
- 200 people
- Sponsor
- Clinical Hospital Centre Zagreb
Diabetes, Diabetes Mellitus, Type 2
Influence of Semaglutide on Pharmacokinetics and Pharmacodynamics of Warfarin and Pharmacokinetics of Metformin in Healthy Subjects
This trial is conducted in Europe and Asia. The aim of the trial is to investigate the influence of semaglutide on pharmacokinetics (the exposure of the trial drug in the body) and pharmacodynamics (the effect of the investigated…
- Conditions
- Diabetes, Diabetes Mellitus, Type 2, Healthy
- Trial name
- NCT02022254
- Testing
- semaglutide, metformin, warfarin
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S