Clinical trials: Type-2 Diabetic Retinopathy
Retinal Neuropathy, Neurodegeneration
Retinal Neurodegeneration In Type 2 Diabetes Mellitus Detected by Optical Coherence Tomography
Evaluation of retinal neurodegeneration in patients with type 2 diabetes mellitus (DM2) without diabetic retinopathy or with mild non proliferative diabetic retinopathy
- Trial name
- NCT04808804
- Testing
- Optical Coherence Tomography (OCT)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Artificial Intelegence, Diabetic Retinopathy Associated With Type 2 Diabetes Mellitus
Application of Artificial Intelligence in Early Detection of Eye Complications in Diabetics
The goal of this pragmatic trial is to test the benefit of using artificial intelligence-based eye screening i.e, a fundus camera device in the early detection of eye complications in diabetics.
- Conditions
- Artificial Intelegence, Diabetic Retinopathy Associated With Type 2 Diabetes Mellitus, Macular Edema Due to Type 2 Diabetes Mellitus
- Trial name
- AI (NCT05655117)
- Testing
- AI based eye screening
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- The New Model of Care, Hail Health Cluster
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Retinal Function in Diabetic Patients Without Retinopathy
The primary purpose was to assess, in diabetic patients without diabetic retinopathy and control subjects, color vision, contrast sensitivity, electroretinography, and flicker-induced vasodilatation using the Dynamic Vessel…
- Trial name
- NEURODIAB (NCT00839150)
- Where
- France
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Diabetic Retinopathy
Correlation Between HBA1c Level and Thickness of Both Macula and Choroid in Patients With Type 2 Diabetes Mellitus
Diabetic retinopathy (DR) is a frequent cause of visual impairment, and the leading cause of blindness in those of working age, but it develops silently along years, producing symptoms only in late stages.
- Trial name
- NCT05778370
- Testing
- Swept Source Optical Coherence Tomography(Topcon DRI Triton)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Assiut University
Diabetes Mellitus, Diabetic Retinopathy
Evaluation of Early Retinal Nerve Injury in Type 2 Diabetes Patients Without Diabetic Retinopathy
The object of this study is to investigate the damage to the retinal nerve fiber layer (RNFL) and ganglion cell complex layer (GCL+) in diabetic patients without retinal microangioma as detected by fundus fluorescein angiography…
- Conditions
- Diabetes Mellitus, Diabetic Retinopathy, Nerve Injury
- Trial name
- NCT03970161
- Testing
- routine ophthalmic examination
- Where
- China
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Diabetic Retinopathy, Type 2 Diabetes Mellitus
The Relationship Between Advanced Glycation Endproducts and Diabetes
The overall purpose of this COMIRB application is to perform a cross-sectional pilot study to aid in the design of a prospective epidemiologic study for an NIH grant application.
- Trial name
- NCT02662010
- Where
- United States
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Type 2 Diabetic Retinopathy
The Effect Evaluation of Continuous Nursing Intervention in Patients With Type 2 Diabetic Retinopathy
Objective: To evaluate the application effect of continuous nursing intervention in type 2 diabetic retinopathy (DR), and to explore its clinical application value.
- Trial name
- NCT05716308
- Testing
- A continuous nursing intervention group was established.
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Diabetic Retinopathy, Diabetic Retinopathy Associated with Type 2 Diabetes Mellitus
Early Retinal Neurodegeneration As Risk Factor, Biomarker and Pharmacological Target of Diabetic Retinopathy
Despite the evidence that diabetic retinopathy (DR) remains the first cause of blindness among the working-age population, it lacks a specific preventive treatment.
- Trial name
- 2022-12376008 (NCT06582472)
- Testing
- Ophthalmological examination including imaging assessments, confocal analysis of cornea, Dynamic Vessel Analyzer (DVA)
- Where
- 2 sites in Italy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- IRCCS Ospedale San Raffaele
Diabetes Mellitus, Type 2 Diabetes
The Hong Kong Diabetes Biobank
Asia is in the midst of an epidemic of diabetes. Epidemiological figures suggest that there are more than 110 million people affected by diabetes in China, with a significant proportion of young adults already affected.
- Conditions
- Diabetes Mellitus, Type 2 Diabetes, Type 1 Diabetes, Diabetic Nephropathies
- Trial name
- HKDB (NCT05282680)
- Testing
- prospective observational study
- Where
- Hong Kong
- Volunteers
- 48,000 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Non-proliferative Diabetic Retinopathy, Diabetes Mellitus Type 2
Efficacy of Ubiquinone and Combined Antioxidant Therapy in Non-proliferative Diabetic Retinopathy
The purpose of this study is to evaluate the efficacy of ubiquinone and combined antioxidant therapy on progression, clinical regression, oxidative stress markers and mitochondrial dysfunction in non-proliferative diabetic…
- Trial name
- NCT02062034
- Testing
- Ubiquinone, Combined antioxidant therapy
- Where
- Mexico
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Guadalajara
Type 2 Diabetes Mellitus Diabetic Retinopathy Cognitive Dysfunction
The Potential of Optical Coherence Tomography Angiography (OCTA) to Detect Early Cognitive Dysfunction in Diabetic Patients
Diabetic Retinopathy (DR) is one of the most common complications of diabetes, and its association with cognitive dysfunctions is becoming an increasingly frequent research interest.
- Trial name
- NCT07135440
- Testing
- OCT angiography RTVue XR Avanti; Optovue, Inc, Fremont, California, USA
- Where
- Bosnia and Herzegovina
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Dr. Sefic Eye Polylcinic and Optical Studio
Diabetic Retinopathy, Type 2 Diabetes
Enriched Eggs for Retina Health in Type 2 Diabetes
Diabetes mellitus has been declared a major public health issue. Among the complications of the disease, retinopathy can have a significant impact on mobility and quality of life for individuals living with diabetes.
- Trial name
- NCT04496817
- Testing
- Docosahexaenoic Acid and Lutein Enriched Eggs, Regular Eggs
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Diabetes Mellitus
Study on Tear Proteins in Diabetic Retinopathy of Type 2 Diabetics
Diabetes mellitus is becoming a global epidemic. There is a need to devise a non invasive method for detection of diabetes and its related complication.
- Trial name
- NCT00698698
- Where
- Pakistan
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Diabetic Retinopathy, Neurodegeneration
Glycemic Control and Retinal Microvascular Changes
The goal of this prospective, observational study is to compare in the association of glycemic control and retinal microvascular changes in patients with type 2 diabetes mellitus (T2DM) without diabetic retinopathy (DR).
- Conditions
- Diabetic Retinopathy, Neurodegeneration, Blood Sugar; High
- Trial name
- NCT06150495
- Where
- South Korea
- Volunteers
- 259 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital