Clinical trials: Type1 Diabetes
Prediabetes, Diabetes Type 1
An Exploratory Clinical Trial to Generate Whole Blood Samples for Analysing Genetic Polymorphisms
G (guanine nucleotide binding) proteins associating with G protein-coupled receptors (GPCR) are key players in the pathogenesis of obesity and diabetes and are targets of pharmacotherapeutic inter-ventions.
- Conditions
- Prediabetes, Diabetes Type 1, Diabetes Type 2
- Trial name
- NCT02057497
- Volunteers
- healthy volunteers welcome
- Sponsor
- Profil Institut für Stoffwechselforschung GmbH
Type 1 Diabetes Mellitus
Exercise Training Intervention in Children With Type 1 Diabetes
Type 1 diabetes mellitus (T1DM) is associated with multiple co-morbidities, such as hypertension, dyslipidemia, coronary heart disease and osteoporosis. The foundation of these conditions lays in childhood.
- Trial name
- Diabex (NCT01220479)
- Testing
- Exercise training program
- Where
- Switzerland
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Preclinical Imaging Biomarkers of Alzheimer's Disease Neuropathology in Young Adults With Youth-onset Diabetes: a Proof-of-concept Study
The goal of the study is to characterize preclinical Alzheimer's Disease and related dementias (AD/ADRD) neuropathology in a selected group of young adults with youth-onset diabetes, and an age-similar group of young adults…
- Conditions
- Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Diabetes, Youth Onset
- Trial name
- NCT05350514
- Testing
- PI-2620 tracer
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Parkinson Disease, Diabetes Mellitus, Type 1
Biological Sample Collection for Research and Biobanking
The New York Stem Cell Foundation (NYSCF) Research Institute is performing this research to study different conditions and diseases by using cells from the body (such as skin or blood cells).
- Conditions
- Parkinson Disease, Diabetes Mellitus, Type 1, Macular Degeneration, ALS
- Trial name
- NCT04270604
- Testing
- Biological sample collection
- Where
- United States
- Volunteers
- 1,279 people, healthy volunteers welcome
- Sponsor
- New York Stem Cell Foundation Research Institute
Diabetes Mellitus, Type 1
Estrogen and Diabetes
Diabetes has recently been referred to as "the epidemic of the 21st century". The reason why women with type 1 diabetes have a 2-3 fold greater risk of cardiovascular disease (CVD) compared to men with type 1 diabetes is…
- Trial name
- NCT03436992
- Testing
- Antioxidant Cocktail, Resveratrol
- Where
- 2 sites in United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Augusta University
Healthy Subjects Without Type 1 Diabetes
Continuous Glucose Sensor Profiles in Non-Diabetic Subjects
The Juvenile Diabetes Research Foundation (JDRF) Glucose Sensor Study group is carrying out a large, randomized clinical trial to assess the efficacy, safety and cost-effectiveness of use of real-time continuous glucose monitors…
- Trial name
- NCT00717977
- Testing
- Continuous glucose monitor
- Where
- 10 sites in United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Jaeb Center for Health Research
Exercise, Healthy Participants
Inter- and Intraindividual Variability of the Acute Glucose Response to Exercise in Healthy Adults and People Living With Type 1 Diabetes: A Cross-over Replicate Trial
The goal of this clinical trial is to investigate if blood glucose responses are similar between and within individuals in response to standardized exercise in adults with and without Type 1 diabetes.
- Conditions
- Exercise, Healthy Participants, Glucose Variability, Type 1 Diabetes (T1D)
- Trial name
- NCT07209930
- Testing
- Exercise, Rest
- Where
- Ireland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Type 1 Diabetes
Stem Cell Educator Therapy in Type 1 Diabetes
The translational potential to the clinical applications of cord blood stem cells has increased enormously in recent years, mainly because of its unique advantages including no risk to the donor, no ethical issues, low risk of…
- Trial name
- NCT01350219
- Testing
- Stem Cell Educator
- Where
- 4 sites in China, Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Throne Biotechnologies Inc.
Type 1 Diabetes, Celiac Disease
Combined Antibody Screening for Celiac and Diabetes Evaluation
The CASCADE Study (Combined Antibody Screening for Celiac and Diabetes Evaluation) is an observational study whose primary goal is to show that population-based screening for advanced prediction of type 1 diabetes (T1D) and…
- Trial name
- CASCADE (NCT04677699)
- Testing
- Combined Risk Score
- Where
- United States
- Volunteers
- 64,410 people, healthy volunteers welcome
- Sponsor
- Pacific Northwest Research Institute
Diet Habit, Type I Diabetes
How Type I Diabetes Responds to Different Diets (Normoglucidic or Ketogenic) During Physical Activity at Altitude
To date, no study has shown the effects of diets (normoglucidic or ketogenic) on type I diabetes during physical activity (hiking, ski touring) at altitude.
- Conditions
- Diet Habit, Type I Diabetes, Activity, Motor, Control
- Trial name
- DIAREAL (NCT06242548)
- Testing
- physical activity outings in the mountains at a level already practised by the subjects, while maintaining their usual diet (normoglucidic or ketogenic)
- Where
- France
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Metropole Savoie
Diabetes Mellitus, Type 1
Safety and Efficacy of Medtronic Extended Mio 30 Infusion Set
The purpose of this study is to evaluate the Extended Mio 30 infusion set (EM30IS) 7-day functioning compared to the regular Mio 30 infusion set (M30IS) 3-day functioning.
- Trial name
- NCT05544643
- Testing
- Medtronic Extended Mio 30 Infusion Set
- Where
- 2 sites in Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Type 1 Diabetes Mellitus
Establishment of Screening Pathway for High-Risk Population of Type 1 Diabetes
This study aims to establish a system for identifying and screening high-risk individuals for type 1 diabetes (T1D) and a standardized management pathway for high-risk individuals. It is a prospective cohort study.
- Trial name
- NCT07468474
- Testing
- Gene polymorphic detection
- Where
- China
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Type 1 Diabetes, Overweight
Impact of Obesity on Microvascular Insulin Action and Cardiorespiratory Fitness in Type 1 Diabetes
The purpose of this study is: To see if insulin resistance (how sensitive your muscle tissue is to insulin) is associated with lower cardio fitness in people with Type 1 diabetes compared to healthy controls, before and after a…
- Trial name
- ZQL010 (NCT07573228)
- Testing
- Exercise training
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Type 1 Diabetes
The Impact of Continuous Glucose Monitoring Use on Sleep in Parents of Children With Type 1 Diabetes Mellitus
The purpose of this prospective exploratory study is to compare sleep quality and sleep-wake patterns in parents of children with type 1 diabetes (T1D) before and several weeks after initiating using real-time continuous glucose…
- Trial name
- NCT01425255
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Hypoglycemia, Diabetes Mellitus, Type 1
A Pilot Study of Nocturnal Hypoglycemia Prevention in Type 1 Diabetes Using the Vigilant Diabetes Management Companion
A single center pilot study assessing the Vigilant Diabetes Management Companion for the prevention of recurrent nocturnal hypoglycemia in type I diabetes patients.
- Trial name
- NCT02906891
- Testing
- Vigilant Diabetes Management Application
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- InSpark Technologies, Inc.
Diabetes Mellitus, Insulin Hypoglycemia
Information and Communication Technology Based Centralized Clinical Trial Monitoring System for Insulin Dose Adjustment
This is a 24-week, open-label, randomized, multi-center trial conducted in three tertiary hospitals. There are three follow-up measures; at baseline, post-intervention at Week 12, and Week 24.
- Conditions
- Diabetes Mellitus, Insulin Hypoglycemia, Insulin-dependent Diabetes Mellitus
- Trial name
- ICT (NCT03112343)
- Testing
- Algorithm-based feedback messages, Personal Health Record
- Where
- South Korea
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Diabetes Mellitus, Osteoporosis
Type 1 Diabetes Mellitus Effect on Bone Mineral Density
Because the diabetics are fracturing at a younger age than the general population (12), this leads us to believe there are significant factors that lead to fracture in Type 1 diabetes mellitus (DM) other than bone mineral density…
- Trial name
- NCT01633684
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Creighton University
Type 1 Diabetes Mellitus
To Evaluate if Wide Blood Sugar Fluctuations Lead to Injury of Heart Function and Heart Nerves
This proposal will test if, in patients with type 1 diabetes, wide blood glucose fluctuations lead to the injury to heart nerves , called cardiac autonomic neuropathy (CAN), and to impaired heart contractile (pumping) function…
- Trial name
- NCT01170832
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Pregnant Women, Diabetes Type 1
Factors Associated With Cesarean Delivery in Women With Type 1 Diabetes
Introduction : Cesarean rate varies from 45% to 73% in the literature in patient with diabetes type 1. Having a prior C-section is the most important risk factor.
- Conditions
- Pregnant Women, Diabetes Type 1, Cesrean Delivery
- Trial name
- NCT03538106
- Where
- France
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Diabetes Mellitus, Type 1
Healthy Outcomes for Muscle with Exercise in T1D
Over 300,000 people in Canada suffer from Type 1 Diabetes (T1D), a chronic condition whose incidence rate has been increasing in Canada every year by 5.1% (higher than the global average).
- Trial name
- HOME T1D (NCT05740514)
- Testing
- Exercise, De-training
- Where
- Canada
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- McMaster University