Clinical trials: Type1 Diabetes Mellitus
Type 1 Diabetes
STEP: Social Support To Empower Parents
This RCT intervention provides parental social support (informational, affirmational, and emotional) using parent mentors (experienced in the management of the chronic illness) for mothers and fathers of young children newly…
- Trial name
- STEP (NCT00480493)
- Testing
- STEP
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Massachusetts, Worcester
Diabetes Mellitus, Type 1, Diabetes Mellitus
Investigating Genetic Risk for Type 1 Diabetes
The objective of this study is to determine the percentage of children with genetic markers putting them at increased risk of developing type 1 diabetes, and to offer the opportunity for these children to be enrolled into a phase…
- Conditions
- Diabetes Mellitus, Type 1, Diabetes Mellitus, Glucose Metabolism Disorders, Metabolic Disease
- Trial name
- INGR1D (NCT03503747)
- Where
- United Kingdom
- Volunteers
- 15,640 people
- Sponsor
- University of Oxford
Diabetes, Diabetes Mellitus, Type 1
Efficacy and Safety of Insulin Aspart in Subjects With Type 1 or Type 2 Diabetes
This trial is conducted in Asia. The aim of this trial is to compare the efficacy of postprandial plasma glucose of two treatment regimens in Chinese subjects.
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- NCT00593255
- Testing
- soluble human insulin, insulin aspart, insulin NPH
- Where
- 5 sites in China
- Volunteers
- 220 people
- Sponsor
- Novo Nordisk A/S
Type 1 Diabetes
Efficacy and Safety of an Artificial Intelligence Tool for Carbohydrate Counting (Tiabete) in Children and Adults With Type 1 Diabetes Mellitus
IntroductionType 1 Diabetes Mellitus (T1DM) requires lifelong exogenous insulin therapy, along with self-management strategies, such as carbohydrate counting, to appropriately adjust insulin doses in response to meals.
- Trial name
- Tiabete (NCT07150052)
- Testing
- Artifical intelligence in whatsapp
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- University of Sao Paulo
Diabetes, Diabetes Mellitus, Type 1
Special Survey for Type 1 or Type 2 Diabetic Patients
This study is conducted in Japan. The aim of this study is to evaluate the incidence of severe hypoglycaemia episodes under normal clinical practice for patients with type 1 or type 2 diabetes.
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- NCT01487408
- Testing
- insulin aspart
- Where
- Japan
- Volunteers
- 1,463 people
- Sponsor
- Novo Nordisk A/S
Diabetes Mellitus, Type 1
PK/PD Study of Gan & Lee's Insulin Glargine Injection in Comparison to Lantus in Type 1 Diabetes
This is a Phase 1, exploratory, single dose, randomized, double-blind, two-way cross over, pilot, glucose clamp study to assess pharmacokinetic and pharmacodynamic effects of Gan \& Lee's insulin glargine injection in comparison…
- Trial name
- NCT02506647
- Testing
- Gan & Lee insulin glargine followed by Lantus, Lantus followed by Gan & Lee insulin glargine
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Gan and Lee Pharmaceuticals, USA
Type1diabetes
Two Narrative Medicine Interventions in Type 1 Diabetes
a randomized prospective study aims at comparing the impact of a "living theater" session with a simple "writing workshop " on emotional distress (Problem Areas in Diabetes Questionnaire PAID) and illness perception ( Illness…
- Trial name
- NCT03365349
- Testing
- participating in a session of "living theatre", writing workshop
- Volunteers
- 87 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Insulin Dependent Diabetes, Non Insulin Dependent Diabetes
Evaluation and Comparison of Noninvasive Blood Glucose Concentrations
Comparison of noninvasive glucose measurement performance versus standard invasive reference measurements.
- Conditions
- Insulin Dependent Diabetes, Non Insulin Dependent Diabetes, Gestational Diabetes
- Trial name
- NCT01745900
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- VeraLight, Inc.
Type 1 Diabetes, Hypoglycemia
Glycemic Effects of Morning Only, Evening Only or Twice Daily Insulin Glargine in Patients With Type 1 Diabetes
This research is a prospective, randomized, cross-over study that is being done to compare the effect of morning only, evening only and twice daily insulin glargine (Lantus®) on hypoglycemia (blood glucose level <70 mg/dL) as…
- Trial name
- NCT00869414
- Testing
- Evening only administration of insulin glargine, Morning only administration of insulin glargine, split dose insulin glargine
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Johns Hopkins University
Type 1 Diabetes
Glycaemic Load and Pre-meal Insulin Doses in Type 1 Diabetes Patients
The aim of this study is to compare the feasibility and the efficacy on short-term glucose control of pre-meal insulin doses adjustment made on the bases of the glycemic load or of the carbohydrates content of the meal in…
- Trial name
- GLUT (NCT01978704)
- Testing
- Adjustment of pre-prandial insulin doses on the bases of glycaemic load of the meal, Adjustment of pre-prandial insulin doses on the bases of carbohydrates content of the meal
- Volunteers
- 9 people
- Sponsor
- Federico II University
Autoimmune Diabetes
Autoimmune Diabetes: Markers of the Disease and Treatment of Latent Autoimmune Diabetes in Adults (LADA)
Autoimmunity is the main cause of diabetes type 1 and an important factor as cause of Latent Autoimmune Diabetes in Adults (LADA).
- Trial name
- NCT01148238
- Volunteers
- healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Type 1 Diabetes
Closed-loop Control of Glucose Levels (Artificial Pancreas) for 60 Hours in Adults With Type 1 Diabetes
Closed-loop strategy is composed of three components: glucose sensor to read glucose levels, insulin pump to infuse insulin and a dosing mathematical algorithm to decide on the required insulin dosages based on the sensor's…
- Trial name
- NCT01966393
- Testing
- 60-hours intervention
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- Institut de Recherches Cliniques de Montreal
Type 1 Diabetes
Combination Therapy With Sitagliptin and Lansoprazole to Restore Pancreatic Beta Cell Function in Recent-Onset Type 1 Diabetes
Sanford Research/USD proposes to study the combination therapy of oral administration of sitagliptin and lansoprazole versus placebo for the preservation of pancreatic beta cells still present in patients with recent-onset…
- Trial name
- REPAIR-T1D (NCT01155284)
- Testing
- Sitagliptin and Lansoprazole
- Where
- 3 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Sanford Health
Type 1 Diabetes Mellitus
Screening of Subjects With Type I Diabetes to Determine Eligibility for Islet Transplantation
Protocol to screen potential subjects for islet transplantation
- Trial name
- NCT02004964
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Rodolfo Alejandro
Diabetes Mellitus, Type 1
The Effect of Nutrition Education on Glycemic Control in Patients With Type 1 Diabetes
The study aims to elucidate whether patients with T1D initiating sensor monitoring experience greater improvement in glycemic control (HbA1c) when provided with structured nutrition education compared to those initiating sensor…
- Trial name
- NCT06264271
- Testing
- structured nutrition intervention
- Where
- Czechia
- Volunteers
- 329 people
- Sponsor
- Charles University, Czech Republic
Type 1 Diabetes Mellitus
Comparison Between Dexcom G5 Mobile Continuous Glucose Monitoring (CGM) System and the FreeStyle Libre Flash Glucose Monitoring System
1. The accuracy of the sensors (Dexcom G5 vs FreeStyle Libre Flash glucose monitoring) will be evaluated by simultaneous wearing of the 2 sensors during 2 weeks.
- Trial name
- NCT03602963
- Testing
- Dexcom G5 Mobile CGM system
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Jessa Hospital
Type1 Diabetes Mellitus
PET-CT Scan Method to Monitor Pancreatic B-Cell Loss in Diabetes Mellitus
The pancreas is an organ that plays major roles in the digestion of food. A part of the pancreas called islet beta-cells produces insulin, which regulates the amount of glucose (a sugar) present in the blood at all times.
- Trial name
- NCT00633763
- Testing
- 18F-fallypride
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Type 1 Diabetes Mellitus
Efficacy and Safety Study of DiaPep277 in Newly Diagnosed Type 1 Diabetes Adults
This study will look at the treatment effect of DiaPep277 on preservation of beta-cell function, as defined by meal-stimulated secretion of insulin.
- Trial name
- DIA-AID2 (NCT01103284)
- Testing
- DiaPep277
- Where
- 75 sites in United States, Austria and 12 more
- Volunteers
- 475 people
- Sponsor
- Andromeda Biotech Ltd.
Diabetes Mellitus, Type 1
Trajectories in Insulin Sensitivity Across MEnstrual cycleS in Women With Type 1 Diabetes
Standardized longitudinal data collection of diabetes management relevant factors in women with T1D (insulin requirements, glucose variability, nutritional information, and menstrual cycle information) to identify categories of…
- Trial name
- TIMES (NCT06282055)
- Testing
- No intervention
- Where
- Switzerland
- Volunteers
- 350 people
- Sponsor
- DCB Research AG
Diabetes Mellitus, Type 1, Monogenic Diabetes
Monogenic Diabetes Misdiagnosed as Type 1
The study has two aims: 1. To (1a) determine the frequency of monogenic diabetes misdiagnosed as type 1 diabetes (T1D) and (2) to define an algorithm for case selection. 2.
- Conditions
- Diabetes Mellitus, Type 1, Monogenic Diabetes, Neonatal Diabetes, Maturity-onset Diabetes in the Young (MODY)
- Trial name
- ADDAM (NCT03988764)
- Testing
- None AHT
- Where
- Canada
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre