Clinical trials: Type1 Diabetes Mellitus
Wolfram Syndrome 1, Optic Atrophies, Hereditary
Does Recessive Optic Atrophy Due to WFS1 Exist?
All patients with Wolfram syndrome and recessive optic atrophy due to a mutation of the WFS1 from a single Center were included in a retrospective study.
- Trial name
- NCT07336966
- Testing
- analyse study
- Volunteers
- 45 people
- Sponsor
- Hôpital Necker-Enfants Malades
TYPE 1 DIABETES
β-cell Function in Type 1 Diabetes May Not Be As Low As Presumed
Enhancing endogenous insulin production in type 1 diabetic patients (T1DP) can improve glycemic control and decrease complications and rates of mortality.
- Trial name
- NCT02199470
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people
- Sponsor
- Gonca Incemehmet Tamer
Diabetes Mellitus, Type 1
Avoidance of Hyperglycaemia in People With Type 1 Diabetes
This study aims to learn more about avoidance of hyperglycaemia in adults with type 1 diabetes. People who attend a type 1 diabetes clinic will be invited to complete a number of self-report questionnaires and a survey.
- Trial name
- HYPE (NCT04732780)
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 253 people
- Sponsor
- Imperial College London
Type 1 Diabetes
Insulin Analogues and Severe Hypoglycaemia
Severe hypoglycaemia is hampering the lives of many diabetic patients. The effect on the occurrence of severe hypoglycaemia during two different insulin regimens are to be investigated.
- Trial name
- NCT00346996
- Testing
- insulin levemir / aspart, human insulin /insulin isophane
- Where
- Denmark
- Volunteers
- 179 people
- Sponsor
- Lise Tarnow
Type 1 Diabetes
ACT Stress Management in Type 1 Diabetes
For many people living with type 1 diabetes it is a challenge to achieve good glucose control. Barely 20% reaches the goal level and many people experience self-care as complex, demanding and stressful.
- Trial name
- NCT02914496
- Testing
- Acceptance and Commitment Therapy (ACT)
- Where
- Sweden
- Volunteers
- 81 people
- Sponsor
- Karolinska Institutet
Type 1 Diabetes Mellitus
A Study of Infusion Site Pain After Infusion of Excipients in Participants With Type 1 Diabetes Mellitus
The main purpose of this study is to evaluate the effect of excipients sodium citrate and treprostinil without insulin on local infusion site pain in participants with type 1 diabetes mellitus (T1DM) on continuous subcutaneous…
- Trial name
- NCT05067270
- Testing
- Sodium Citrate, Treprostinil, Humalog diluent
- Where
- 2 sites in Germany
- Volunteers
- 40 people
- Sponsor
- Eli Lilly and Company
Diabetes Mellitus, Type 1, Diabetes Distress
Use of an Online Intervention for the Treatment of Diabetes Distress in Patients With Type 1-Diabetes
This study will investigate whether an online intervention can be helpful in reducing diabetes distress in people with type 1 diabetes and elevated diabetes distress, compared to individual counselling sessions (online…
- Trial name
- NCT06436456
- Testing
- Online psychological intervention, Individual psychological intervention
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Odense University Hospital
Type 1 Diabetes
Closed-loop Control of Overnight Glucose Levels in Adults and Adolescents With Type 1 Diabetes
Closed-loop strategy is composed of three components: glucose sensor to read glucose levels, insulin pump to infuse insulin and a dosing mathematical algorithm to decide on the required insulin dosages based on the sensor's…
- Trial name
- NCT01905020
- Testing
- Carbohydrate-rich meal, Exercise
- Where
- 3 sites in Canada
- Volunteers
- 28 people
- Sponsor
- Institut de Recherches Cliniques de Montreal
Type 1 Diabetes
Evaluation of The Postprandial Impact of Automated Priming Bolus for Full Closed Loop Insulin Delivery
The purpose of this study is to understand the impact of the automated priming boluses on the safety and feasibility of a new fully automated AP controller.
- Trial name
- Rocket-BPS (NCT05528770)
- Testing
- FCL+BPS, FCL
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Marc Breton
Type 1 Diabetes Mellitus
Pizza-Salami Study in Children and Adolescents With Type 1 Diabetes
The Pizza-Salami-Study aims to investigate the efficacy of carbohydrate plus fat/protein (CFP) counting compared with carbohydrate (CARB) counting using normal and dual-wave bolus in sensor-augmented pump therapy in children and…
- Trial name
- NCT01400659
- Testing
- CFP counting, CARB counting
- Volunteers
- 42 people
- Sponsor
- Kinderkrankenhaus auf der Bult
Diabetes Mellitus, Type 1
Trial Comparing Metabolic Efficiency of Islet Graft to Intensive Insulin Therapy for Type 1 Diabetes's Treatment
Efficacy of pancreatic islet transplantation at 6 months compared to an intensive insulin therapy for 2 categories of patients: patients with unstable diabetes and patients who underwent kidney transplantation.
- Trial name
- TRIMECO (NCT01148680)
- Testing
- Islet Graft
- Where
- 9 sites in France, Switzerland
- Volunteers
- 50 people
- Sponsor
- University Hospital, Grenoble
Type 1 Diabetes Mellitus
LEA29Y (Belatacept) Emory Edmonton Protocol
Type 1 diabetes is an autoimmune disease in which the insulin-producing pancreatic beta cells are destroyed, resulting in poor blood sugar control.
- Trial name
- LEEP (NCT00468403)
- Testing
- Allogeneic Pancreatic Islet Cells, Belatacept, Basiliximab
- Where
- 2 sites in United States, Canada
- Volunteers
- 10 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Type 1 Diabetes
Exercise in Adolescents With Type 1 Diabetes
Regular physical activity is an important part of diabetes management in adolescents with type 1 diabetes (T1D). Increased physical activity has several beneficial effects such as improved lipid profile, insulin sensitivity and…
- Trial name
- NCT04418869
- Testing
- Exercise bouts
- Volunteers
- 8 people
- Sponsor
- Region Örebro County
Diabetes, Diabetes Mellitus, Type 1
A Survey to Evaluate Diabetes Management, Control, Chronic Complications, Psychosocial Aspects of Diabetic Subjects in Korea
This study is conducted in Asia. The aim of this observational study is to evaluate current status of diabetes management, control, and complications in diabetic subjects in Asia.
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- DiabCare Asia (NCT00918151)
- Testing
- No treatment given
- Where
- South Korea
- Volunteers
- 1,932 people
- Sponsor
- Novo Nordisk A/S
Type-1 Diabetes
Canadian Bone Strength Development Study
The goal of this project is to learn about differences in bone development between children with and without type-1 diabetes (T1D). The main questions this study aims to answer are: 1.
- Trial name
- CanBSDS (NCT06287840)
- Where
- Canada
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Diabetes Mellitus, Type 1, Ischemia
Non-enhanced Magnetic Resonance Angiography of Diabetic Ischemic Lower Limbs
Diabetic foot ulcers often progresses after many years of diabetes where the patients system is so damaged that normal heeling of ulcers cannot happen.
- Conditions
- Diabetes Mellitus, Type 1, Ischemia, Foot Ulcer
- Trial name
- NCT01614379
- Where
- 2 sites in Denmark
- Volunteers
- healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Diabetes Mellitus, Type 1
A Study in Participants With Type 1 Diabetes Mellitus
The purpose of this study is: To compare the blood sugar control of LY2605541 with insulin glargine after 78 weeks of treatment.
- Trial name
- IMAGINE 1 (NCT01481779)
- Testing
- Glargine, LY2605541, Insulin Lispro
- Where
- 51 sites in United States, Austria and 7 more
- Volunteers
- 455 people
- Sponsor
- Eli Lilly and Company
Diabetes Mellitus, Type 1
Effect of Basal-Bolus Closed-Loop Co-Administration of Insulin and Pramlintide on Improving the Glycemic Control in Type 1 Diabetes
The closed-loop delivery system is composed of an insulin pump, a continuous glucose sensor and a dosing algorithm that calculates the insulin dose to infuse based on sensor readings.
- Trial name
- NCT02814123
- Testing
- 24-hour inpatient intervention
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- McGill University
Diabetes, Diabetes Mellitus, Type 1
Efficacy, Safety and Preference Study of a Insulin Pen PDS290 vs. a Novo Nordisk Marketed Insulin Pen in Diabetics
This trial is conducted in the United States of America (USA). The aim of this clinical trial is to assess and compare the effect on blood sugar control of insulin detemir and insulin aspart or insulin detemir alone administered…
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Delivery Systems
- Trial name
- NCT00773279
- Testing
- FlexTouch®, FlexPen®
- Where
- 65 sites in United States
- Volunteers
- 242 people
- Sponsor
- Novo Nordisk A/S
Type 1 Diabetes
Feasibility Study of 2000 IU Per Day of Vitamin D for the Primary Prevention of Type 1 Diabetes
Type 1 diabetes is a common chronic disease of childhood. It is not yet preventable. Multiple daily injections of insulin, tests of blood sugar, and careful dietary planning are required lifelong to prevent long-term…
- Trial name
- NCT00141986
- Testing
- vitamin D3
- Where
- Canada
- Volunteers
- 9 people
- Sponsor
- Canadian Diabetes Association