Clinical trials: Type2diabetes
Type2diabetes, Obesity
Effect of a Vegetarian Meal on the Physiology of Insulin Response in Patients With Type 2 Diabetes Mellitus and Obesity
The role of diet in determining glucose intolerance and its progression towards T2DM has been extensively investigated. A 2017 meta-analysis showed that a vegetarian diet is inversely associated with the risk of developing…
- Conditions
- Type2diabetes, Obesity, Diet, Healthy, Nutrition, Healthy
- Trial name
- VEG-EAT (NCT06152536)
- Testing
- Vegetarian Meal
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- IRCCS San Raffaele
Type2diabetes
High Intensity Body-weight Circuit Training Feasibility and Efficacy for in Middle Aged Persons With Type 2 Diabetes
This research study proposes to quantify the efficacy of the novel high intensity body-weight circuit (HIBC) training intervention on metabolic profile, body composition, and health related fitness exercise in middle aged persons…
- Trial name
- NCT05571384
- Testing
- high intensity body-weight circuit
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Kennesaw State University
Type2diabetes, Rheumatoid Arthritis
Understanding Ayurveda Disease Conditions and Treatment Responses
The goal of this observational study is to assess Prakriti \& Vikriti in patients visiting OPD of IIISM department, SRM hospital.
- Conditions
- Type2diabetes, Rheumatoid Arthritis, Osteo Arthritis Knee, Skin Diseases
- Trial name
- NCT06167226
- Testing
- Personalized Ayurveda treatment protocol
- Where
- India
- Volunteers
- 497 people
- Sponsor
- Ayurai Private Limited
Type2Diabetes, Hypertension
Digital Care for Holistic Health in Older Adults With Diabetes and Multimorbidity
The purpose of this study was to explore the effectiveness of the "Digital Care Community Common Good" program in improving disease control indicators, self-management abilities, depression, and quality of life among patients…
- Conditions
- Type2Diabetes, Hypertension, Dyslipidemia, CKD
- Trial name
- NCT07310849
- Testing
- Digital Care Community Common Good Program, Usual Care
- Where
- Taiwan
- Volunteers
- 169 people
- Sponsor
- Chang Gung University of Science and Technology
Type2Diabetes, Severe Mental Disorder
The PsychOsis and Diabetes Service Model (PODS) Population Profile Study.
People with severe mental illness (SMI), defined as psychotic and bipolar disorders, die 17-20 years earlier than the general population, the most common cause of death being cardiovascular diseases (CVD).
- Trial name
- NCT05456984
- Where
- 9 sites in United Kingdom
- Volunteers
- 125 people
- Sponsor
- King's College London
Postprandial Hyperglycemia, Overweight and Obesity
A Study of Biochemical Response to Alternative Proteins
The overall objective of this research is to determine the digestive faith and health impact of protein and fiber rich foods in different food matrices in type 2 diabetes risk population.
- Conditions
- Postprandial Hyperglycemia, Overweight and Obesity, Type2diabetes
- Trial name
- COBRA (NCT06253728)
- Testing
- High fiber and protein meal, Control
- Where
- Finland
- Volunteers
- 24 people
- Sponsor
- University of Eastern Finland
Type2Diabetes
TRE in Type 2 Diabetes (See Food Study 3)
Hyperglycemia in patients with Type 2 Diabetes Mellitus is initially treated with metformin coupled with intentional caloric restriction, which is difficult to sustain due to multiple barriers, including acquiring the necessary…
- Trial name
- SFS3 (NCT05290246)
- Testing
- Time restricted eating, Caloric reduction
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Type2diabetes
Combining Gene Variants to Improve Risk Prediction for Metabolic (Dysfunction)- Associated Fatty Liver Disease and Its Progression to Cirrhosis in Indian Individuals With Type 2 Diabetes
Type 2 diabetes and metabolic (dysfunction)-associated fatty liver disease (MAFLD) often exist together. The prevalence of MAFLD is about 15-30% in healthy people and around 60-70% in people with type 2 diabetes.
- Trial name
- NCT06289387
- Where
- India
- Volunteers
- 1,000 people
- Sponsor
- Medanta, The Medicity, India
Type2diabetes
Correlation of Xanthelasma With Atherosclerosis, Hepatic Fat and Fibrosis
Patients with diabetes with clinical feature of Xanthelasma will show increased Atherosclerosis. Objectives: Primary 1. To correlate xanthelasma and its severity to pulse wave velocity and atherosclerosis as see in carotid…
- Trial name
- NCT05945030
- Testing
- Clinical Examination
- Where
- India
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Diabetes Foundation, India
Stroke, Hypertension
Factors of Control Hypertension or Type 2 Diabetes on the Severity of Stroke and Survival Rates Within 1 Year in Trat
The purpose of this study was to study factors for controlling hypertension or type 2 diabetes before stroke diagnosis on the severity level when a stroke occurs, NIHSS, and survival rate after having a stroke in 1 year in Trat…
- Conditions
- Stroke, Hypertension, Type2diabetes
- Trial name
- NCT06288269
- Testing
- Severity of Stroke and 1 year survival
- Where
- Thailand
- Volunteers
- 291 people
- Sponsor
- Phrapokklao Hospital,Thailand
Type2diabetes
Validation of Existing Diabetes Risk Models in a Swedish Population
The goal of this observational study is to validate existing non-invasive diabetes clinical prediction models in a Swedish population.
- Trial name
- NCT05609266
- Volunteers
- 115,642 people, healthy volunteers welcome
- Sponsor
- Umeå University
Hemodialysis, Type1diabetes
Improved Glycemic Control in Diabetic Patients in Hemodialysis Using Continuous Glucose Monitoring (CGM)
The 16-week trial is an open-label cross-over trial which includes heamodialysis patients with T2D and T1D on insulin therapy. During one period, patients carry a non-blinded CGM.
- Conditions
- Hemodialysis, Type1diabetes, Type2Diabetes
- Trial name
- NCT05678712
- Testing
- Access to CGM data (Dexcom G6)
- Where
- Denmark
- Volunteers
- 23 people
- Sponsor
- Aalborg University Hospital
Type2diabetes
Integration of a Trained Language Model to Improve Glycemic Control With the My Heart Counts Smartphone App
Type 2 diabetes (T2D) is one of the most common and fastest growing diseases, affecting 1 in 8 adults (nearly 800 million) worldwide by 2045. Sedentary behavior and increased adiposity are major risk factors for T2D.
- Trial name
- NCT06596330
- Testing
- Validation of language model prompts in increasing short-term physical activity, Assessment of long-term changes to physical activity and glycemic control
- Sponsor
- Stanford University
Type 2 Diabetes Mellitus (T2DM), Type2Diabetes
Post-market SUrveiLlance RegiStry for the Endogenex System (Endogenex PULSE Registry)
This registry is designed to collect long-term data and support ongoing post-market surveillance of real-world data for the Endogenex System.
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Type2Diabetes, Diabetes Mellitus, Type 2, Type 2 Diabetes
- Trial name
- NCT07197775
- Where
- 4 sites in United States, Australia
- Volunteers
- 500 people
- Sponsor
- Endogenex, Inc.
Type2Diabetes
Study to Evaluate the Pharmacokinetic Characteristics of Pegylated Exenatide Injection (PB-119) in Subjects With Different Degrees of Renal Insufficiency and Matched Subjects With Normal Renal Function
This study is a single-dose, parallel grouping, open-label phase I clinical study to evaluate the PK characteristics and safety of single subcutaneous injection of PB-119 in subjects with different degrees of renal insufficiency…
- Trial name
- NCT05328843
- Testing
- PB119
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- PegBio Co., Ltd.
Type2diabetes, Type 2 Diabetes Treated With Insulin
The CARING Study: Creating and Restoring Health Through Nutrition Guidance
The CARING study assesses the health benefits of nutrition education for Blue Cross Blue Shield subscribers, as well as potential healthcare cost savings to subscribers and the insurance company.
- Trial name
- NCT05795439
- Testing
- Low-fat, vegan diet
- Where
- United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Physicians Committee for Responsible Medicine
Pre-Gestational Diabetes, Type2diabetes
Successfully Achieving and Maintaining Euglycemia During Pregnancy for Type 2 Diabetes Through Technology and Coaching
The ACHIEVE RCT will measure the effect of the intervention (mHealth app with CGM, provider dashboard, and care team coaching) compared to current standard care (prenatal visits, self-monitored blood glucose, and certified…
- Conditions
- Pre-Gestational Diabetes, Type2diabetes, Pregnancy in Diabetic, Pregnancy, High Risk
- Trial name
- NCT05662462
- Testing
- DEXCOM G7 PRO Continuous Glucose Monitor, Patient mHealth app linked to a provider dashboard, Care team coaching for medical and social needs (HUB)
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Ohio State University
Diabetes Mellitus, Type 2, Diabetes
Evaluation of Fuling Yunhua Granules and Dihuang Baoyuan Granules in Drug Naive Type 2 Diabetes Patients
The goal of this investigator-initiated clinical trial is to investigate the efficacy and safety of sequential therapy of Fuling Yunhua Granules (prescription A) and Dihuang Baoyuan Granule (prescription B) in the treatment of…
- Conditions
- Diabetes Mellitus, Type 2, Diabetes, Type2diabetes
- Trial name
- NCT06575478
- Testing
- Fuling Yunhua Granules, Dihuang Baoyuan Granules
- Where
- China
- Volunteers
- 95 people
- Sponsor
- Beijing Supreme Life Pharmaceutical Technology Co., Ltd.
Obesity, Type2diabetes
Metabolic Effects of Bariatric Arterial Embolization vs Bariatric Surgery
Obesity and Type 2 diabetes mellitus (DMT2) are two of the most common chronic diseases of the Western society. Obesity is one critical factor in DMT2 development, with weight loss having profound beneficial effects on DMT2 and…
- Conditions
- Obesity, Type2diabetes, Bariatric Surgery Candidate, Metabolic Disease
- Trial name
- BEOD (NCT05859022)
- Testing
- Roux-en-Y gastric By-pass (RYGB) surgery, Bariatric Arterial Embolization (BAE) procedure
- Where
- Portugal
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Nova de Lisboa
Type 2 Diabetes Mellitus, Type2diabetes
Continued Access to the Endogenex System for Participants in the ReCET Pivotal Study
This study is designed to collect real-world data on the safety and performance of the Endogenex System in the cohort of participants who were originally randomized to the sham control arm of the ReCET Study.
- Conditions
- Type 2 Diabetes Mellitus, Type2diabetes, Diabetes Mellitus, Type 2, Type 2 Diabetes
- Trial name
- NCT07197788
- Testing
- Endogenex System
- Where
- 11 sites in United States, Australia
- Volunteers
- 50 people
- Sponsor
- Endogenex, Inc.