Clinical trials: Ulcer, Pressure
Intubation Complication, Pressure Injury
Pressure Over Nasotracheal Intubation Related Nasal Alar Injury
Nasotracheal intubation can cause injury and hemorrhage of nasal mucosa and nasal alar. The investigators measure the actual pressure at the angle between nasotracheal tube and nasal alar, analyze the relationship of clinical…
- Trial name
- NCT03735160
- Testing
- pressure sensor
- Where
- Taiwan
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mackay Memorial Hospital
Diabete Mellitus, Peripheral Neuropathy
The Pressure Relieving Capacity of Siliconepads Compared to Felted Foam to Relieve Caput Metatarsal 2 in a Population With Diabetes
To evaluate the clinical effectiveness of siliconepads and if they could be an alternative to felted foam used in offloading high risk pressure areas in the plantar forefoot region using plantar pressure measurements.
- Trial name
- Siliconepads (NCT07172763)
- Testing
- Siliconepad, Felted foam
- Volunteers
- 80 people
- Sponsor
- University Hospital, Ghent
Newborn, Pressure Injury
Pressure Injuries' Prevention in Newborn Infants Admitted to NICU
Nasal Continuous Positive Airway Pressure (NCPAP) is a respiratory support for neonates with Respiratory Distress Syndrome (RDS) and represents the gold standard for RDS treatment in many Neonatal Intensive Care Units (NICU).
- Trial name
- NCT04293601
- Testing
- interventional nursing care, Standard nursing care
- Where
- Italy
- Volunteers
- 280 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Pressure Injury
Prevention of Pressure Ulcers in Patients at Medium to High Risk of Developing Pressure Ulcers and Using the DOMUS 4 / AUTO Motorized Air Mattress
The aim of the study is to determine the clinical value of using a powered alternating pressure air mattress (P-APAM) in the prevention of pressure injury (PI) in patients at medium to high risk.
- Trial name
- NCT05472974
- Testing
- Use of a powered alternating pressure air mattress
- Where
- 5 sites in France
- Volunteers
- 86 people
- Sponsor
- Wellell France
Colonic Adenoma, Colonic Cancer
R vs L Lateral Decubitus Positioning in Colonoscopy
Colonoscopy continues to be the gold standard in detecting precancerous lesions in the colon. It relies on adequate visualization of the bowel wall to see and remove such lesions.
- Trial name
- NCT03355495
- Testing
- Colonoscopy - Position Change
- Where
- Canada
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Memorial University of Newfoundland
Pressure Sore, Orthopedic Disorder
Body Temperature Changes and Early Postoperatıve Pressure Sore
This study aims to determine effect of body temperature changes during total knee arthroplasty surgery on early postoperative pressure sore formation.
- Conditions
- Pressure Sore, Orthopedic Disorder, Hypothermia, Nursing Caries
- Trial name
- NCT05552599
- Testing
- woolen blanket
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Hitit University
Lung Cancer, Lung Lobectomy
Effects of Different I:E Ratio on Intrapulmonary Shunt Fraction and Oxygenation During One Lung Ventilation in the Lateral Decubitus Position
The purpose of this study is to investigate effect of increasing inspiratory time (I:E ratio 1:1) on intrapulmonary shunt fraction and oxygenation during one lung ventilation in the lateral decubitus position.
- Trial name
- NCT01499212
- Testing
- I:E ratio
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Yonsei University
Chronic Wound, Burn Wound
Wound Healing Endpoint and Recurrence
This study is a continuation of a previously approved protocol conducted at Ohio State University and Indiana University. The first two aims of the original protocol have been completed, and this protocol will finish enrollment…
- Conditions
- Chronic Wound, Burn Wound, Diabetic Foot Ulcers, Pressure Ulcers
- Trial name
- NCT02577120
- Testing
- Epiceram Skin Barrier Function, Vaseline Petroleum Jelly
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- Sashwati Roy
Foot Ulcer, Diabetic
Treatment Study of Negative Pressure Wound Therapy for Diabetic Foot Wounds
On behalf of a consortium of 19 health insurance companies the Institute for Research in Operative Medicine as part of the University of Witten / Herdecke gGmbH is planning and conducting a clinical study evaluating the efficacy…
- Trial name
- DiaFu (NCT01480362)
- Testing
- Negative Pressure Wound Therapy, Standard Wound Therapy
- Where
- 42 sites in Germany
- Volunteers
- 360 people
- Sponsor
- University of Witten/Herdecke
Venous Leg Ulcer (VLU), Diabetic Foot Ulcer (DFU)
A Real World Data Collection of Human Amniotic Membrane(s) on Diabetic Foot Ulcers, Venous Leg Ulcers, Pressure Ulcers and Post Operative Wounds
This study is designed to evaluate the effectiveness of Tri-Membrane Wrap™, Membrane Wrap™ and Membrane Wrap-Hydro™ compared to the effectiveness of Standard of Care alone though a retrospective data collection.
- Conditions
- Venous Leg Ulcer (VLU), Diabetic Foot Ulcer (DFU), Pressure Ulcer (PU)
- Trial name
- NCT07078968
- Testing
- Tri-Membrane Wrap™, Membrane Wrap™, Membrane Wrap-Hydro™
- Where
- 4 sites in United States
- Volunteers
- 500 people
- Sponsor
- BioLab Holdings
Diabetic Feet
How Shoes With Rocker Soles Affect Walking
The purpose of this study is to compare how 3 special types of shoes with rocker-shaped soles help people with foot deformities to walk better.
- Trial name
- NCT00006438
- Testing
- Shoes with Rocker Soles
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Pressure Ulcers
Increasing Fluids in Older Adults to Prevent & Treat Pressure Ulcers
The purpose of this study is to determine whether providing extra fluid to nursing home residents will help prevent or heal pressure ulcers.
- Trial name
- NCT00507650
- Testing
- Fluid intervention, Fluid intervention plus 10 ml/kg/day
- Volunteers
- 63 people
- Sponsor
- University of California, San Francisco
Pressure Sores
Prevention of Pressure Sores in the Prone Position in ARDS Patients
A nursing strategy to prevent pressure sores in the prone position in Acute Respiratory Distress Syndrome (ARDS) patients. A multicenter controlled prospective stepped wedge trial.
- Trial name
- PSA (NCT03125421)
- Testing
- standard preventive methods of pressure sores, experimental multifaceted preventive methods of pressure sores
- Where
- France
- Volunteers
- 160 people
- Sponsor
- Hospices Civils de Lyon
Spinal Cord Injury
Developing a Home Telehealth Program to Manage Pressure Ulcers in SCI/D
The Veteran's Health Administration (VHA) is a national leader in using distance technology to monitor patients' self-care via an in-home messaging device with disease management protocols (DMPs).
- Trial name
- NCT00624806
- Testing
- Daily telephone calls, Weekly telephone calls
- Where
- 2 sites in United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Pressure Injury, Venous Ulcer
MicroMatrix® Flex in Tunneling Wounds
To evaluate the safety and performance of MicroMatrix® Flex in subjects with wounds complicated by tunneling and/or undermining features.
- Conditions
- Pressure Injury, Venous Ulcer, Necrotizing Soft Tissue Infection, Diabetic Ulcers
- Trial name
- NCT06629506
- Testing
- MicroMatrix® Flex, MicroMatrix® UBM Particulate, Cytal® Wound Matrix 2-Layer
- Where
- 3 sites in United States
- Volunteers
- 25 people
- Sponsor
- Integra LifeSciences Corporation
Diabetic Foot Ulcers, Venous Stasis Ulcer
Negative Pressure Wound Therapy Registry
The goal of the Negative Pressure Wound Therapy Registry (NPWTR) for Wounds is to provide real world patient data from electronic health records submitted to meet Stage 2 Meaningful Use in order to understand the effectiveness…
- Conditions
- Diabetic Foot Ulcers, Venous Stasis Ulcer, Pressure Ulcer, Surgical Wound Dehiscence
- Trial name
- NPWTR (NCT02467998)
- Testing
- NPWT
- Where
- United States
- Volunteers
- 50,000 people
- Sponsor
- U.S. Wound Registry
Neuralgia, Chronic Pain
Ketamine's Efficiency in the Treatment of Chronic Pain: Kynurenin Pathway
The kynurenine pathway is involved in hyperalgesia. This pathway is activated by inflammation. Ketamine would interact with the kynurenine pathway and inflammation.
- Conditions
- Neuralgia, Chronic Pain, Inflammation
- Trial name
- KEKU1 (NCT03513822)
- Testing
- Ketamine 10 MG/ML, Midazolam 1 MG/ML
- Where
- France
- Volunteers
- 48 people
- Sponsor
- Redar
Urinary Catheter-Related Discomfort, Pressure Injury
Impact of Urinary Catheter Fixation on Meatal Pressure Injury in Male Patients in the Intensive Care Unit
Meatal pressure injury refers to the injury and ulceration of the head and shaft of the penis resulting from the constant pressure of an indwelling catheter.
- Trial name
- NCT06967116
- Testing
- Procedure Steps
- Where
- Turkey (Türkiye)
- Volunteers
- 248 people
- Sponsor
- Merve Zorlu
Foot Ulcer, Diabetic
Reduction of Plantar Pressure in Neuropathic Diabetic Foot Patients Using Insoles With Removable Pegs Design
The purpose of this study was to determine if insoles with removable pegs could effectively reduce the plantar aspect pressure with the aid of in-shoe plantar pressure analysis for guidance of peg removal.
- Trial name
- NCT01699100
- Testing
- device
- Volunteers
- 26 people
- Sponsor
- Taichung Veterans General Hospital
Hard-to-heal Wounds, AI (Artificial Intelligence)
AI-Based Wound Monitoring: Automated Wound Progression Assessment Via Marker-Free Image Sequence
This study aims to develop a low-cost, marker-free intelligent wound assessment system that can analyze wound photos taken with a standard smartphone.
- Conditions
- Hard-to-heal Wounds, AI (Artificial Intelligence), Wound Care, Pressure Injuries
- Trial name
- NCT07619430
- Testing
- Marker-free wound image registration technology
- Where
- Taiwan
- Volunteers
- 1,000 people
- Sponsor
- National Taiwan University Hospital