Clinical trials: Ultraviolet Exposure
Sunburn, Ultraviolet Radiation Exposure
Test of Interventions to Prevent Skin Cancer Among Danes on Vacation in High UV Index Sunny Destinations
The aim of the study is to test a series of developed effective interventions targeting Danes going on vacation to sunny destinations to decrease sunburn by increasing use of shade, hats, protective clothing, and sunscreen to…
- Conditions
- Sunburn, Ultraviolet Radiation Exposure, Skin Cancer, Malignant Melanoma
- Trial name
- NCT03607578
- Testing
- Other: Control Group - Minimal Intervention, Experimental: Protection Routine 1, Experimental: Protection Routine 2
- Where
- Denmark
- Volunteers
- 1,548 people, healthy volunteers welcome
- Sponsor
- Brian Køster
Pigmentation, Redness
Photoprotection Efficacy With Sunscreen Formulas Containing the Cyclic Merocyanine Long-UVA Absorber MCE Under UV Day Light Exposure
To evaluate the photo-protector effect of BC_3 (E212657) formulated in SPF compared to SPF alone on UV Day Light induced pigmentation in healthy volunteers
- Trial name
- NCT04866797
- Testing
- cyclic merocyanine
- Where
- Romania
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- L'Oreal
Altitude, Ultraviolet Rays
Ultraviolet Exposure, Antioxidant Use and Skin Erythema at Extreme High Altitude
With the increasing tourism and adventure travel into extreme environments comes the need to reassess the required protection against ultraviolet (UV) radiation and possible other oxidative stresses.
- Conditions
- Altitude, Ultraviolet Rays, Antioxidants, Oxidative Stress
- Trial name
- NCT00685438
- Where
- Nepal
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Aging
Effect of Topical Sulforaphane on Skin Fragility Seen in Skin Aging and With Ultraviolet Exposure
This study aims to compare the expression of keratins before and after application of sulforaphane (SF) to determine whether this agent alters skin fragility seen in both intrinsic and extrinsic skin aging and UV light exposure.
- Trial name
- NCT03126539
- Testing
- Sulforaphane, Narrow-band Ultraviolet B exposure, 4 mm skin punch biopsy
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Vitamin D Deficiency
The Role of Narrowband Ultraviolet B Exposure in the Maintenance of Vitamin D Levels During Winter
The investigators investigated the ability of narrowband ultraviolet B (nbUVB) treatment in the maintenance of vitamin D levels achieved during the summer in Finland.
- Trial name
- NCT02275650
- Testing
- nbUVB
- Where
- 2 sites in Finland
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Joint Authority for Päijät-Häme Social and Health Care
Skin Inflammation, Skin Melanoma
Effects of Ultraviolet B Exposure Using a Ultraviolet Skin Care Device on Vitamin D Production and Immune Response in Healthy Adults
Vitamin D regulates various physiological functions, including calcium homeostasis, bone health, and potentially reducing cancer risks.
- Trial name
- NCT06625918
- Testing
- Ultraviolet B exposure to produce vitamin D synthesis
- Where
- South Korea
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Wonju Severance Christian Hospital
Healthy
UVB: Skin to Gut Study
This research will explore the potential effects of Narrow-Band Ultra Violet B (NB-UVB) radiation on the intestinal microbiota composition and confirm a regulatory skin-to-gut axis during baseline conditions.
- Trial name
- NCT03962673
- Testing
- NB-UVB light exposure
- Where
- Canada
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Sun Damaged Skin
Singlet Oxygen Quantification After Skin Exposure to Ultraviolet A (UVA) Light
The objective of this study is quantification of singlet oxygen species in the skin after exposure to Ultraviolet A (UVA) light
- Trial name
- NCT05865431
- Testing
- Zinc Oxide and Avobenzone
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Healthy Volunteers
The Effect of Violet Device Dosed Ultra Violet-C Light (UV-C) Exposure on Healthy Hand Skin
The purpose of this trial is to determine the safety of ultraviolet light (UV-C) irradiation as a method to sanitize hands instead of chemical-based sanitizers.
- Trial name
- NCT05313555
- Testing
- Ultraviolet Light (UV-B), Ultraviolet lights (UV-C) - 1 cycle, Ultraviolet lights (UV-C) - 10 cycles
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Epidermis, Ultraviolet Exposure
A Clinical Study to Evaluate the Efficacy and SPF of Two Test Materials According to an Adaptation of the Guidelines of the FDA Sunscreen Drug Products for Over-the-Counter Human Use
Approximately 70 subjects (35 subjects per light and dark group) will be enrolled in this clinical study (to complete with a minimum of 10 subjects per skin type (I-VI) to assess the effects of known UV Radiation dosage on light…
- Trial name
- NCT07789639
- Testing
- Hybrid sunscreen, Chemical sunscreen, No sunscreen
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Good Molecules, LLC
Skin Pigmentation, Photobiology
A Study to Evaluate the Cutaneous Effects of Deep Ultraviolet A +/- High-Energy Visible Blue Light Exposure
The objective of this study is to assess the level of pigmentation following an acute exposure of skin to light regimens representative of portions of the natural sunlight spectrum and that contain Deep UVA wavelengths with or…
- Trial name
- NCT06654102
- Testing
- Deep UVA Irradiation, Deep UVA+HEV Blue Light Irradiation
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Peripheral Neuropathic Pain, Nociceptive Pain
Determine the Effect of AZD3161,Injected Intradermally, on Quantitative Sensory Testing Variables in Normal and Ultraviolet-C (UVC) Exposed Skin in Healthy Volunteers
The purpose of this study is to investigate the effect of AZD3161 on mechanical pain sensitivity and axon reflex flare in normal and ultraviolet C irradiated skin.
- Trial name
- NCT01240148
- Testing
- AZD3161, Lidocaine
- Where
- United Kingdom
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Sunscreen Sensitivity, Ultraviolet-Induced Change in Normal Skin
Photoprotection Efficacy With Sunscreen Formulas Containing the Cyclic Merocyanine Long-UVA Absorber MCE Under Long-UVA Exposure.
To evaluate the photo-protector effect of BC_3 (E212657) formulated in SPF compared to SPF alone on long-UVA induced pigmentation in healthy volunteers.
- Trial name
- NCT04865120
- Testing
- cream cyclic merocyanine
- Where
- Romania
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- L'Oreal
Skin Aging
Effect of Topical Sulforaphane on Skin Aging and With Ultraviolet and Visible Light Exposure
The study is to compare the expression of both keratin 16 and 17 before and after application of sulforaphane on both photoprotected and photoexposed area, and to determine whether these findings alter skin aging as well as skin…
- Trial name
- NCT03730649
- Testing
- Sulforaphane (broccoli sprout extract), UV or visible light
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Skin Cancer
EUREKA: Evaluating Ultraviolet Radiation Exposure in Kids for Adaptive Intervention
This project will pilot a Just In Time Adaptive Intervention (JITAI) approach to providing feedback on child UVR exposure to children and their parents, with the ultimate goal of improving child use of sun protection strategies…
- Trial name
- EUREKA (NCT07204704)
- Testing
- EUREKA Intervention
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of Utah
Ultraviolet B-Induced Skin Erythema
Mangosteen Gel Applied Before NB-UVB Exposure in Healthy Adults
This study examined whether a gel containing mangosteen (*Garcinia mangostana*) pericarp extract could reduce short-term skin redness caused by narrowband ultraviolet B (NB-UVB) exposure when applied before irradiation.
- Trial name
- NCT07849829
- Testing
- Topical Garcinia mangostana Pericarp Extract Gel 5%, Topical Garcinia mangostana Pericarp Extract Gel 10%, Topical Garcinia mangostana Pericarp Extract Gel 20%
- Where
- Indonesia
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Hasanuddin University
Melanoma
Use of Fiber-optic Probe for Non-invasive Diagnosis of Melanoma and Assessment of Impact of Ultraviolet (UV) Exposure on Skin
This study is designed to collect information about melanoma using a research probe, a device placed only on the skin. This study will investigate whether using the probe to examine skin lesions could improve the accuracy of…
- Trial name
- NCT01085396
- Where
- 3 sites in United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Ultraviolet Light Burn
Molecular Responses Caused by UV Exposure of Human Skin
Pilot study to investigate the impact of exposure of human skin to low levels of UV light on blood markers related to stress in healthy women.
- Trial name
- SMR-UV (NCT05383664)
- Testing
- Ultra Violet Light Exposure
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Access Business Group
Skin Cancer, Heat Tolerance
Title: ICARUS - Psycho-physiological Profiling of Low and High Heat-resilient Individuals
The escalating environmental heat-stress associated with global warming is a societal challenge with large and potential harmful consequences for humans.
- Conditions
- Skin Cancer, Heat Tolerance, Heat-related Illness, Hyperthermia
- Trial name
- ICARUS (NCT07510061)
- Testing
- Controlled Heat and Ultraviolet Radiation Exposure Protocol
- Where
- 2 sites in Denmark, Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Melanoma
The Response of Serum 25-Hydroxyvitamin D to Incidental Ultraviolet Light Exposure
1.1 To detect reproducible variations of serum 25-hydroxyvitamin D levels throughout the course of one year in relationship to objectively measured levels of ultraviolet exposure.
- Trial name
- NCT00832533
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- New Mexico Cancer Research Alliance