Clinical trials: Unfavorable Cervix
Medical Induction of Labor Affecting Newborn
Premature Rupture of Membranes With a Bishop Score<6: Comparison of Medical Induction/Expectant Management
The study is intended to compare expectant management and on presentation labor induction in women with premature rupture of membranes. The means of labor induction and cervical ripening are either oxytocin or dinoprostone.
- Trial name
- NCT02825641
- Testing
- Oxytocin, Dinoprostone
- Where
- Israel
- Volunteers
- 458 people
- Sponsor
- Rambam Health Care Campus
Induction of Labor
Single Balloon Catheter Compared With Double Balloon Catheter for Ripening of the Unfavorable Cervix
The purpose of this study is to compare between single balloon catheter and double balloon catheter for ripening the cervix among pregnant with unfavorable cervix.
- Trial name
- NCT00690040
- Testing
- Foley catheter, Atad catheter
- Where
- Israel
- Volunteers
- 293 people
- Sponsor
- HaEmek Medical Center, Israel
Nulliparous Women Who Scheduled for Labor Induction
Concurrent Membrane Sweeping With Dinoprostone Versus Dinoprostone in Labor Induction of Nulliparas at Term With an Unfavorable Cervix
To compare concurrent membrane sweeping with dinoprostone versus dinoprostone in labor induction for nulliparas at term with an unfavorable cervix
- Trial name
- NCT01792375
- Testing
- Concurrent membrane sweeping with Dinoprostone, 10mg Dinoprostone vaginal insert
- Where
- South Korea
- Volunteers
- 192 people
- Sponsor
- Seoul National University Hospital
Scarred Uterus
A Comparison of Balloon Catheter Versus Ocytocin for Cervical Ripening on Scarred Uterus With Unfavorable Cervix
Increasing cesarean rate in France is worrying. Different methods are described for ripening labor : the use of prostaglandins is described but maybe dangerous for patients with scarred uterus and is not recommended.
- Trial name
- NCT01711060
- Testing
- oxytocin, balloon catheter
- Where
- 7 sites in France
- Volunteers
- 204 people
- Sponsor
- Poitiers University Hospital
Delivery
Comparing the Efficiency of Cervical Ripening BALLoon (Cook) to the DINOprostone (Propess) for the Cervical Maturation in Case of Unfavorable Cervix (Bishop <6) in the Population of Obese Pregnant Women (BMI >= 30 kg/m²)
At the moment in France, one delivery on four is induced for a medical indication. In this context, the practitioners are exposed to an additional difficulty when the clinical examination of the patient reveals a unfavorable…
- Trial name
- BALLODINO (NCT02649920)
- Testing
- Cervical ripening balloon, Dinoprostone
- Where
- 2 sites in France
- Volunteers
- 2 people
- Sponsor
- Centre Hospitalier Departemental Vendee
Unfavorable Cervix for Induction of Labor
Induction of Labor in Patients With Unfavorable Cervical Conditions
Artificial ripening of the cervix and induction of labor remain as one of the therapeutic challenges in Obstetrics. The method widely used, the intravenous administration of Oxytocin, is associated with prolonged induction…
- Trial name
- NCT00604487
- Testing
- ARD (Atad Ripener Device), AID (Atad double balloon Instillation Device), folly catheter
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Induction of Labor
Induction of Labor - Comparison Propess With Prostaglandin E2 Vaginal Gel and Balloon Catheter
One of every four births in the Western world is induced, usually due to the risk of maternal and fetal morbidity. There are several methods of labor induction, pharmacological and mechanical.
- Trial name
- NCT06803992
- Testing
- Dinoprostone vaginal insert, Dinoprostone gel and Foley catheter balloon
- Where
- Israel
- Volunteers
- 140 people
- Sponsor
- HaEmek Medical Center, Israel
Early Amniotomy, Unfavorable Cervix
Early Amniotomy After Vaginal Prostaglandin E2 for Induction of Labor at Term: a Randomized Clinical Trial
This study evaluates the effectiveness and safety of early amniotomy after vaginal prostaglandin E2 for induction of labor at term.
- Trial name
- PGE2 (NCT02856724)
- Testing
- PGE2
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Cervical Ripening, Induction of Labor
Heated Saline in Cervical Balloon for Labor Induction, a RCT
This study is a single-center, randomized, two-arm, controlled trial, including women requiring cervical ripening during the process Induction of Labor using Balloon catheter (BC).
- Conditions
- Cervical Ripening, Induction of Labor, Unfavorable Cervix, Mechanical Method
- Trial name
- NCT05864326
- Testing
- Warm group, Room temperature group
- Where
- Switzerland
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Begona Martinez de Tejada
Induction of Labor, Unfavorable Cervix
Cervical Ripening With the Double Balloon Device for 6 Hours Compared With 12 Hours
This study will evaluate the insertion of double balloon device (DBD) for cervical ripening for 12 h vs 6 hours.
- Trial name
- DoubleCRIB (NCT03045939)
- Testing
- cervical ripening device
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bnai Zion Medical Center
Premature Rupture of Fetal Membranes, Labor, Induced
PGE2 Followed by Oxytocin vs Oxytocin in Term PROM (POXY-PROM)
This study is being done to learn more about the best way to start labor for pregnant women whose water breaks at term before labor begins, a condition called term prelabor rupture of membranes (term PROM).
- Conditions
- Premature Rupture of Fetal Membranes, Labor, Induced, Cervical Ripening
- Trial name
- POXY-PROM (NCT07366359)
- Testing
- Sequential Induction: Dinoprostone Followed by Oxytocin, Immediate Oxytocin Induction
- Where
- Vietnam
- Volunteers
- 450 people
- Sponsor
- National Hospital of Obstetrics and Gynecology
Induction of Labour
Double Foley Catheter For Cervical Ripening
To compare the efficacy of three mechanical devices for pre-induction of labour cervical ripening: the Single Foley Catheter, Double Foley Catheter (a new handmade device) and Cook cervical ripening balloon.
- Trial name
- NCT04454346
- Testing
- Double Foley Catheter For Ripening The Unfavorable Cervix
- Where
- Turkey (Türkiye)
- Volunteers
- 222 people
- Sponsor
- Etlik Zubeyde Hanım Women's Health Care, Training and Research Hospital
Cervical Ripening, Unfavorable Cervix
Oxytocin vs Prostaglandins for Labor Induction of Women With an Unfavorable Cervix After 24h of Cervical Ripening
Twenty-two percent of deliveries in France are induced. In cases where labor is induced and cervix is unfavorable, cervical ripening prior oxytocin administration is advised in order to reduce the risk of cesarean delivery.
- Trial name
- OPIC (NCT04949633)
- Testing
- Prostaglandins, Oxytocin
- Where
- 14 sites in France
- Volunteers
- 1,494 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Pre-induction Dilation of Cervix
Induction of Labor in Women With Unfavorable Cervix: Dilapan Versus Foley Bulb
Women undergoing mechanical cervical ripening for labor induction will be randomized to Dilapan-S® versus Foley bulb. The investigators hypothesized that osmotic cervical dilators (Dilapan-S®) are as effective as Foley bulb…
- Trial name
- NCT02899689
- Testing
- Dilapan, Foley Catheter
- Where
- 2 sites in United States
- Volunteers
- 419 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Pregnancy Related
Labor Induction With Double Balloon Device, Oral Misoprostol and Concomitant Use of Both
The aim of this study is to compare the rate of cesarean delivery between 3 methods of labor induction: double balloon device, oral misoprostol and combination of the two.
- Trial name
- IDOM (NCT03866772)
- Testing
- Misoprostol Oral Tablet, double balloon device for cervical ripening
- Where
- Israel
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Bnai Zion Medical Center
Trial of Labor After Cesarean, Vaginal Birth After Cesarean
Balloon Catheter Combined With Oxytocin Induction Among the Pregnant Women With Previous Cesarean Section
This study is a multi-center, prospective, observational clinical trial study. 924 full-term pregnant women will be enrolled as subjects, and the ratio of eligible subjects in the two groups is 1:1.
- Conditions
- Trial of Labor After Cesarean, Vaginal Birth After Cesarean, Bishop Score, Failed Mechanical Induction
- Trial name
- NCT05246761
- Testing
- Balloon catheter
- Where
- China
- Volunteers
- 924 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Labor Induction, Induced Delivery
Foley Catheter Versus PGE2 for Labor Induction at Term: a Pilot Study
Induction of labor is one of the most common interventions in obstetrics. In the past decade, the rates of labor induction at term have doubled from approximately 9% to 23% in the United States and from 10% to 20.4% in China.
- Trial name
- NCT04780269
- Testing
- Induction of labor with Foley catheter, Induction of labor with PGE2
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Premature Rupture of Membrane, Unfavorable Cervix
Randomized Control Trial of Intracervical Balloon Placement vs Oxytocin in Women With Term PROM and Unripe Cervices
This study is designed to determine if an intracervical balloon catheter (IBC) is better than oxytocin for induction of labor in the setting of premature rupture of membranes (PROM) or breaking the bag of water prior to onset of…
- Trial name
- NCT03172858
- Testing
- Intracervical balloon catheter, Oxytocin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwestern University
Unfavorable Cervix, Cervical Ripening
Combined Foley Catheter Balloon and PGE2 Vaginal Ovule for Induction of Labor at Term: A Randomized Study
This study evaluates the addition of transcervical Foley catheter balloon and vaginal prostaglandin E2 in induction of labor at term.
- Trial name
- NCT02861079
- Testing
- Foley catheter, PGE2
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Labor, Induced, Cervix Uteri-Diseases
Comparing Outpatient to Inpatient Cervical Ripening Using Dilapan-S®
The target population for our study is women who present for induction of labor. If there is a decision by the obstetrical team to place a mechanical dilator for cervical ripening, the obstetrical team will notify the research…
- Trial name
- HOMECARE (NCT03665688)
- Testing
- Outpatient Dilapan-S, Inpatient Dilapan-S
- Where
- 2 sites in United States
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston