Clinical trials: Unilateral Transfemoral Amputation
Unilateral Transfemoral Amputation in Prosthetic Users
Impact of Anterior Load Carriage on Gait in Individuals With Transfemoral Amputation
This monocentric prospective crossover study aims to evaluate the impact of anterior load carriage on gait performance in individuals with unilateral transfemoral amputation using a prosthesis.
- Trial name
- LOAD TF (NCT07875634)
- Testing
- Anterior Load Carriage During Walking
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Institut Robert Merle d'aubigné
Lower Limb Amputation
A Pilot RCT to Investigate the Use of a Home-based Nintendo Wii Program for Rehabilitation in Older Adults With Lower Limb Amputation
This is a pilot randomized controlled trial to assess the feasibility of a home-based Nintendo Wii Fit program (Wii.n.Walk) to improve walking capacity in older adults with a lower limb amputation.
- Trial name
- NCT01715662
- Testing
- Wii.n.Walk, Wii Big Brain
- Where
- 3 sites in Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Transfemoral Amputation
Use of Passive, Adaptive, and Active Prosthetic Knees in Persons With Unilateral, Transfemoral Amputation
The goals of this study are to assess measured, observed, and self-reported outcomes achieved through the use of passive (mechanical), active(motorized) and adaptive (magnetorheological) prosthetic knee control systems in…
- Trial name
- OPK (NCT02219230)
- Testing
- Active knee (Ossur Power Knee II), Adaptive knee (Ossur Rheo), Passive knee (Various manufacturers)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Washington
Prosthesis User, Amputation
An Investigation of Functional Improvements in the RHEO KNEE Compared to Hydraulic Microprocessor Controlled Knees (MPKs)
The aim of this study was to evaluate the mobility, perceived safety and functioning of unilateral transfemoral (TF) amputees using the Rheo Knee XC compared to their existing prosthetic knee (RHEO KNEE II, III or Genium, X2 or…
- Trial name
- NCT04023578
- Testing
- RHEO KNEE XC
- Where
- 4 sites in United States
- Volunteers
- 15 people
- Sponsor
- Össur Iceland ehf
Analgesia Assessment, Above Knee Amputation
The Analgesic Efficacy of Dexmedetomidine Versus Fentanyl as an Adjuvant to Bupivacaine in Ultrasound Guided Peripheral Nerve Blocks as a Solo Anesthetic Technique in High Risk Patients Undergoing Unilateral Above Knee Amputation .
The aim of this study is to compare the analgesic efficacy and safety of dexmedetomidine versus fentanyl as adjuvants to bupivacaine in ultrasound-guided combined supra-inguinal fascia iliaca and proximal sciatic nerve blocks…
- Conditions
- Analgesia Assessment, Above Knee Amputation, Fentanyl vs Dexmedetomidine
- Trial name
- NCT07640516
- Testing
- Dexmedetomidine, Fentanyl (as Citrate)
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Kasr El Aini Hospital
Transfemoral Amputation, Unilateral Traumatic Amputation of Leg at or Above Knee
Functional Outcomes in Dysvascular Transfemoral Amputees
In older adults, poor circulation in the lower extremities leads to serious health complications including limb loss. In addition, individuals with dysvascular disease also suffer from other co-morbidities like diabetes, coronary…
- Trial name
- CLEG (NCT01537211)
- Testing
- C leg compared to subject's mechanical leg (Otto Bock)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Shirley Ryan AbilityLab
Amputation, Traumatic
The Relationship of Stump Length With Muscle Strength in Patients With Traumatic Unilateral Transfemoral Amputation
Amputation is the loss or removal of a body part such as an arm or leg. It is the last option in trauma treatment and irreversible procedure. Amputation rehabilitation begins in the pre-amputation period.
- Trial name
- NCT05435326
- Volunteers
- 16 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Unilateral Transfemoral Amputation, Unilateral Knee Disarticulation
Real-time Motion Capture and Visual Feedback for Amputation Gait Training
People with transfemoral amputation face challenges such as gait asymmetry, instability, and increased energy consumption due to loss of the knee joint.
- Trial name
- NCT07049198
- Testing
- Real-time 2D motion capture and visual feedback system gait training, Conventional physical therapy group
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Yang Ming Chiao Tung University
Lower Limb Amputation
KinetiGait- Analysis of Depth Camera to Assist Gait Analysis for Unilateral Transtibial/Transfemoral Amputees
This is a feasibility study about implementing and using the KinetiGait gait analysis system in clinical practice to enhance the rehabilitation of service members with lower limb disfunction.
- Trial name
- NCT04431817
- Testing
- KinetiGait
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Lower Limb Amputation Above Knee (Injury)
The CYBERnetic LowEr Imb coGnitive Ortho-prostheis Plus Plus, 2nd Clinical Study (CLs++)
The aim of the project is to evaluate the efficacy of the Cyberlegs X-leg in people with a unilateral transfemoral (above the knee joint) and transtibial (under the knee joint) amputation.
- Trial name
- NCT04129853
- Testing
- Cyberlegs Xleg
- Where
- Belgium
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Unilateral Transfemoral Amputation
Study of Medial-Lateral Center of Pressure Displacement in Unilateral Transfemoral Amputees
The purpose of this study is to examine the path and velocity of the center of mass (CoM) and center of pressure (CoP) during double support of persons walking with a unilateral above-the-knee prosthesis and determine the effects…
- Trial name
- NCT02299674
- Testing
- Level overground ambulation
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Southern California Institute for Research and Education
Unilateral Transfemoral Amputation
A Comparison Between Ischial-Containment and Sub-Ischial Prosthetic Sockets to Determine Their Effects on Secondary Health Conditions
Long-term above-knee prosthesis users are at an increased risk of developing secondary musculoskeletal conditions compared to the general able-bodied population.
- Trial name
- NCT07768072
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Lower Limb Amputation Above Knee (Injury)
The CYBERnetic Lower Limb Cocognitive Ortho-prosthesis Plus Plus, 1st Clinical Study (CLs++)
The aim of the study is to assess the efficacy and the usability of the cyberlegs ++ ortho prosthesis to improve the mobility and the quality of life in transfemoral amputees .
- Trial name
- NCT03376919
- Testing
- CLs++ gait training
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Lower Limb Amputation, Older Adults
Study of WiiFit to Enhance Walking in Older Adult Amputees
WiiNWALK is a 4 week physical activity, with the intervention of a WiiFit, targeted to improve walking capacity in individuals with either a unilateral below-knee or above-knee amputation.
- Trial name
- WiiNWalk (NCT01942798)
- Testing
- Nintendo Wii, Wii Big Brain Academy Degree program
- Where
- 5 sites in Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Limb Injury
Improved Training Program for Fall Prevention of War Fighters
This study will train War Fighters with lower extremity trauma to decrease fall risk.
- Trial name
- RapidRehab (NCT03446131)
- Where
- 4 sites in United States
- Volunteers
- 45 people
- Sponsor
- Mayo Clinic
Amputation, Traumatic
The Relationship Between Thicknesses and Isokinetic Strength of Hip Flexor and Extensor Muscles
The aim of this study is to investigate the relationship of hip muscle thicknesses measured by ultrasonography with hip flexion and extension strength and clinical parameters in prosthesis users with unilateral traumatic…
- Trial name
- NCT05827744
- Testing
- Isokinetic evaluations, Ultrasonographic evaluations
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Amputation
The Effect of Different Microprocessor Knee Prostheses on Mobility and Gait Parameters in Transfemoral Amputees
Microprocessor knee joints are prosthetic knee joints with an integrated processor or a computer that can analyze data. During walking, parameters such as step speed, joint angles, and weight transferred through sensors are…
- Trial name
- NCT04966936
- Testing
- questionnaires for clinical assessments, 2 minute walking test, The gait analysis at the motion analysis laboratory.
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital