Clinical trials: Unruptured Intracranial Aneurysms
Unruptured Intracranial Aneurysms, Pituitary Neuroendocrine Tumor
China Treatment Trial for Tumor in Sellar Region With Unruptured Intracranial Aneurysm
The goal of this observational study is to learn about the treatment strategies for tumor in sellar region with unruptured intracranial aneurysms in the Chinese population.
- Conditions
- Unruptured Intracranial Aneurysms, Pituitary Neuroendocrine Tumor, Craniopharyngioma, Meningioma
- Trial name
- ChTTSRUIA (NCT07809178)
- Testing
- Tumor resection followed by aneurysm treatment, Aneurysm treatment followed by tumor resection, Observation
- Where
- China
- Volunteers
- 608 people
- Sponsor
- Cheng sen
Aneurysm Cerebral (Unruptured)
Multimodal Approach Feasability Study for Untreated and Unruptured Intracranial Aneurysms
This feasibility study aims to evaluate the SYLVER system's ability to visualize intracranial aneurysms in accordance with 3D rotational angiography (3DRA) as the reference technique.
- Trial name
- miniCAN (NCT07864389)
- Testing
- 3D CEUS
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Resolve Stroke
Unruptured Intracranial Aneurysm
Unruptured Cerebral Aneurysm: Prediction of Evolution
The protocol has many assets. A prospective nationwide recruitment allows for the inclusion of a large cohort of patients with UIA. It will combine accurate clinical phenotyping and comprehensive imaging with CAWE screening.
- Trial name
- U-CAN (NCT04578808)
- Testing
- Unruptured intracranial aneurysms
- Where
- 29 sites in France, Netherlands and 1 more
- Volunteers
- 1,000 people
- Sponsor
- Nantes University Hospital
Unruptured Intracranial Aneurysm, Intracranial Aneurysm
Surveillance Versus Treatment of Unruptured Intracranial Aneurysms of Fortuitous Discovery
The goal of this clinical trial is to determine whether a watchful waiting strategy with imaging surveillance is superior to immediate aneurysm treatment in adults with incidentally discovered unruptured intracranial aneurysms…
- Trial name
- STAF (NCT07817511)
- Testing
- Clinical and imaging surveillance, Endovascular or neurosurgical aneurysm treatment
- Where
- France
- Volunteers
- 600 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cerebrovascular Disease, Ischemic Stroke
Florida Cerebrovascular Disease Biorepository and Genomics Center
The purpose of this study is to create a state-wide biorepository and resource center for cerebrovascular diseases in Florida, which will include collecting medical history information and blood from subjects affected by…
- Conditions
- Cerebrovascular Disease, Ischemic Stroke, Transient Ischemic Attack, Intracerebral Hemorrhage
- Trial name
- NCT05491980
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Mayo Clinic
Unruptured Intracranial Aneurysm, Intracranial Bifurcation Aneurysm
Early Complications After Flow Diverter Versus Stent-Assisted Coiling for Unruptured Wide-Neck Intracranial Bifurcation Aneurysms
This prospective real-world cohort study aims to compare early postoperative complications between flow diverter treatment and stent-assisted coiling in patients with unruptured wide-neck intracranial bifurcation aneurysms.
- Conditions
- Unruptured Intracranial Aneurysm, Intracranial Bifurcation Aneurysm, Wide-Neck Aneurysm
- Trial name
- FD-SAC BAS (NCT07754188)
- Testing
- Flow Diverter, Stent-Assisted Coiling
- Where
- 3 sites in China
- Volunteers
- 274 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Unruptured Intracranial Aneurysm
MRI Analysis in the Growth of Cerebral Aneurysms
An intracranial aneurysm is defined as a localized dilatation of the cerebral arteries, which can potentially lead to rupture and subsequent hemorrhagic stroke. The mechanisms by which aneurysms develop and grow remain unknown.
- Trial name
- EPICAVC (NCT06705452)
- Testing
- Additional 4D Flow MRI or additional 4D Flow sequence
- Where
- France
- Volunteers
- 281 people
- Sponsor
- CHU de Reims
Unruptured Intracranial Wide-neck Bifurcation Aneurysms
Flow Diverter Versus Conventional Endovascular Treatment for Unruptured Wide-Neck Bifurcation Aneurysms (FD-BWA Trial)
Brief Summary： The goal of this clinical trial is to compare whether the traditional approach (stent-assisted coiling) is associated with a lower complication rate than flow diverter (Pipeline™) treatment for unruptured…
- Trial name
- FD-BWA (NCT07707076)
- Testing
- Flow Diverter Group, Stent Assisted Coiling Group
- Where
- China
- Volunteers
- 266 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Cerebral Aneurysm, Cerebral Aneurysm Unruptured
Parent Artery Reconstruction for Cerebral Aneurysms Using a Novel Flow Diverter With Surface Modification
The primary objective of this trial is to evaluate the safety and efficacy of the cerebral flow diverter in the endovascular treatment of wide-necked cerebral aneurysms
- Trial name
- NCT05774782
- Testing
- Cerebral flow diverter
- Where
- China
- Volunteers
- 143 people
- Sponsor
- Sinomed Neurovita Technology Inc.
Unruptured Intracranial Aneurysm, Hypertension
China Antihypertensive Trial for Intracranial Aneurysm
The goal of this randomized controlled trial is to evaluate the benefits and safety of controlled hypotension in Chinese patients with unruptured intracranial aneurysms(UIA).
- Trial name
- ChATIA-1 (NCT05941377)
- Testing
- blood pressure lowering
- Where
- China
- Volunteers
- 577 people
- Sponsor
- Beijing Tiantan Hospital
Cerebral Aneurysm Unruptured, Intracranial Pressure
Remifentanil vs Esmolol During Intubation for Cerebral Aneurysm Coil Embolization
Endotracheal intubation may cause significant increases in blood pressure, heart rate, and intracranial pressure, particularly in patients undergoing cerebral aneurysm coil embolization.
- Trial name
- NCT07660861
- Testing
- Remifentanil, Esmolol
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Unruptured Intracranial Aneurysm
Assessment of the Clinical and Economic Impact of Sim&Size, a Simulation Software for Implantable Devices Used in the Treatment of Intracranial Aneurysms: A Prospective Multicenter Study.
In recent years, endovascular treatment of intracranial aneurysms has seen remarkable growth, now surpassing traditional surgical approaches in terms of frequency of use.
- Trial name
- ESSNAI (NCT07433075)
- Testing
- 3D simulation of placement of neurovascular implantable medical device, Manual planning of endovascular procedure
- Where
- 6 sites in France
- Volunteers
- 576 people
- Sponsor
- Sim&Cure
Unruptured Intracranial Aneurysm, Cerebral Aneurysm Unruptured
Comparison of Propofol and Propofol-Ketamine Anesthesia on Optic Nerve Sheath Diameter in Endovascular Cerebral Aneurysm Procedures
This study aimed to compare the effects of propofol-based anesthesia and propofol-ketamine anesthesia on optic nerve sheath diameter (ONSD) in patients undergoing elective endovascular treatment of unruptured intracranial…
- Conditions
- Unruptured Intracranial Aneurysm, Cerebral Aneurysm Unruptured, Cerebral Aneurysms
- Trial name
- ONSD-KP (NCT07542015)
- Testing
- Propofol (Astra-Zeneca), Propofol and Ketamine Mixture (Ketofol)
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Ankara City Hospital Bilkent
Unruptured Intracranial Aneurysm
Treatment Strategies for Unruptured Intracranial Aneurysms in the Chinese Population China Treatment Trial for Unruptured Intracranial Aneurysm (ChTUIA)
The goal of this prospective observational cohort study is to learn about treatment strategies for unruptured intracranial aneurysms in the Chinese population.
- Trial name
- ChTUIA (NCT05844163)
- Testing
- observation
- Where
- China
- Volunteers
- 31,595 people
- Sponsor
- Beijing Tiantan Hospital
Unruptured Intracranial Aneurysm, Headache
Efficacy and Safety of Transcutaneous Auricular Vagus Nerve Stimulation for Postoperative Headache Following Stent-Assisted Coiling of Unruptured Intracranial Aneurysms
The goal of this clinical trial is to evaluate the efficacy and safety of transcutaneous auricular vagus nerve stimulation (taVNS) in reducing postoperative headache among adults undergoing stent-assisted coiling for unruptured…
- Conditions
- Unruptured Intracranial Aneurysm, Headache, Vagus Nerve Stimulations
- Trial name
- IMPACT-HT (NCT07479082)
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation
- Where
- China
- Volunteers
- 440 people
- Sponsor
- Beijing Tiantan Hospital
Unruptured Intracranial Aneurysm, Indobufen
INdobufen Versus asPirin in Endovascular Unruptured Intracranial Aneurysms Treatment (INPUT)
This project aims to evaluate the safety and efficacy of the antiplatelet regimen combining indobufen and clopidogrel in preventing ischemic events after stent-assisted coiling embolization and flow diverter implantation for…
- Trial name
- NCT07089862
- Testing
- Indobufen treatment, Aspirin treatment
- Where
- China
- Volunteers
- 2,500 people
- Sponsor
- Beijing Tiantan Hospital
Subarachnoid Aneurysm Hemorrhage, Unruptured Intracranial Aneurysm
Investigation of Protein Heterogeneity in Extracellular Vesicles Derived From Different Human Blood Circulatory Regions
The goal of this observational study is to learn about the protein heterogeneity in extracellular vesicles (EVs) derived from different human blood circulatory regions of patients with ruptured or unruptured intracranial…
- Trial name
- DBCR-EV-p (NCT07439965)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- The First Hospital of Jilin University
Unruptured Intracranial Aneurysms, Cerebrovascular Event
Efficacy and Safety of Methylprednisolone After Flow-Diverter Stent Implantation in Unruptured Intracranial Aneurysms
Study Title: Testing Methylprednisolone to Prevent Strokes After a Stent Procedure for Brain Aneurysms What is the purpose of this study? This study aims to find out if a short course of a steroid medicine called…
- Conditions
- Unruptured Intracranial Aneurysms, Cerebrovascular Event, Hemorrhagic Stroke, Methylprednisolone
- Trial name
- NCT07353749
- Testing
- Methylprednisolone (Injectable Form)
- Where
- China
- Volunteers
- 864 people
- Sponsor
- Duan Chuanzhi
Unruptured Intracranial Aneurysm, Flow Diverter
Tirofiban for Reduction of Thromboembolic Events in Endovascular Unruptured Aneurysm Repair
To explore whether administering tirofiban in stent-assisted coiling/flow diverting treatments for participants with unruptured intracranial aneurysms can reduce new ischemic lesions on postoperative DWI sequences compared to…
- Conditions
- Unruptured Intracranial Aneurysm, Flow Diverter, Stent-assisted Coiling, Thromboembolic Events
- Trial name
- TEAR (NCT06238115)
- Testing
- Tirofiban, aspirin, clopidogrel
- Where
- China
- Volunteers
- 192 people
- Sponsor
- Beijing Tiantan Hospital
Aneurysm Cerebral, Bifurcation
LUMENS-1 Canada Early Feasibility Study Clinical Investigation Plan
The primary objective of this clinical investigation is to evaluate the early safety and feasibility of the LuSeed Aneurysm Embolization System for treating unruptured intracranial aneurysms (IA).
- Conditions
- Aneurysm Cerebral, Bifurcation, Unruptured Intracranial Aneurysm, Saccular Aneurysm
- Trial name
- NCT07259018
- Testing
- LuSeed Aneurysm Embolization System
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- LuSeed Vascular LTD.