Clinical trials: Unsedated
Healthy
Feasibility, Safety and Utility of Endomicroscopy to Study the Intestines of Unsedated Infants at UVa
The purpose of this study is to demonstrate the feasibility of using the transnasal endomicroscopy (TNE) platform, using intestinal potential difference (IPD) and microbiome brush to evaluate the intestine of unsedated infants.
- Trial name
- NCT05857488
- Testing
- Transnasal introduction tube
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Unsedated Colonoscopy, Water Exchange Colonoscopy
Prospective RCT Of Water Exchange (WE) vs. WE Plus Cap-Assisted Colonoscopy
This is a study to compare two different, but normally, used methods of colonoscopy in patients undergoing colonoscopy without sedation.
- Conditions
- Unsedated Colonoscopy, Water Exchange Colonoscopy, Cap, Colonoscopy Pain
- Trial name
- NCT03160859
- Testing
- Control, Study method
- Where
- 3 sites in United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Water Exchange Colonoscopy
Minimal Water Exchange Versus Left Water Exchange in Unsedated Colonoscopy
Minimal water exchange colonoscopy is theoretically more convenient and faster than water exchange colonoscopy. But few studies compared the differences between the two methods.
- Trial name
- NCT04952142
- Testing
- minimal water exchange
- Where
- China
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Ningbo No. 1 Hospital
Patient Satisfaction
Consented Unsedated Endoscopy in High Risk Patients That Require Anesthesiologist Observation During the Procedure
This study aim to examine the safety and feasibility of unsedated colonoscopy in patients with high risk for sedation (ASA score≥3).
- Trial name
- NCT05842720
- Testing
- un-sedated colonoscopies
- Where
- Israel
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Colonoscopy
Can Simple and Inexpensive Techniques Enhance Patient Comfort
This research study compares two methods of performing colonoscopy without sedation. The standard method is to insert the colonoscope without adding any water to the colon, and when colonic spasms occur during the examination…
- Trial name
- NCT00747084
- Testing
- Colonoscopy
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Colonoscopy, Unsedated
Factors Associated With Pain During Unsedated Colonoscopy
Colonoscopy is the gold standard in the diagnosis and treatment colorectal disease, but due to the uncomfortable or even painful procedure, a part of people unwilling to undergoing the examination and giving analgesic agents were…
- Conditions
- Colonoscopy, Unsedated, Pain
- Trial name
- NCT03420612
- Where
- China
- Volunteers
- 607 people, healthy volunteers welcome
- Sponsor
- Air Force Military Medical University, China
Colon Disease;, Rectal Disease
Ultrafine Endoscope for Colonoscopy in Diagnosis of Colorectal Diseases
This study is the evaluation of ultrafine endoscope (with small caliber and turning radius )for colonoscopy in decreasing abdominal pain of patients . 60 patients will be accepted in this trial.
- Trial name
- NCT02160210
- Testing
- Ultrafine Endoscope
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Youlin Yang ,MD
Colonoscopy Pain
Pre-procedural Risk Score-Based Endoscopist Assignment for Pain Reduction in Unsedated Colonoscopy
This multicenter randomized controlled trial evaluates whether a pre-procedural risk score-based endoscopist assignment strategy reduces intraprocedural pain in high-risk patients undergoing unsedated colonoscopy.
- Trial name
- NCT07713953
- Testing
- Risk Score-Based Endoscopist Assignment
- Where
- China
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Ningbo No. 1 Hospital
Outpatients
The Optimal Timing of Carbon Dioxide Insufflation During Colonoscopy in Unsedated Patients
Insufflation of carbon dioxide (CO2) instead of air can reduce pain resulting from colon distension after colonoscopy because CO2 is rapidly absorbed from the colon and excreted through the lungs.
- Trial name
- NCT01415076
- Testing
- Insufflation with CO2
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
Cecal Intubation Success Rate
Disposable Sheathed Gastroscopic System for Cecal Intubation
A novel disposable sheathed gastroscope system has been shown to be safe and more efficient in clinical practice during gastroscopy.
- Trial name
- NCT02495480
- Testing
- A novel disposable sheath
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Yuqi He
Gastrointestinal Diseases, Digestive System Diseases
Warm Water and Unsedated Colonoscopy
Unsedated or slightly sedated colonoscopy has fast recovery time, less cost and lower or no incidence of drug-related side effects. May be slightly painful or discomforting for the patient.
- Trial name
- WW (NCT01463319)
- Testing
- air insufflation, warm water irrigation
- Where
- 2 sites in Italy
- Volunteers
- 818 people, healthy volunteers welcome
- Sponsor
- Presidio Ospedaliero Santa Barbara