Clinical trials: Upper Abdomen Cancers
Erector Spinae Block Analgesia
Aalgesic Efficacy of Erector -Spinae Technique With Levobupvicaine in Patients Undergoing Upper Abdominal Cancer Surgery
To study analgesic efficacy \&safety of bilateral erector spinae block for upper abdominal cancer surgery as apart of multimodal analgesia.
- Trial name
- NCT04315454
- Testing
- Levobupivacaine
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- South Egypt Cancer Institute
Gastrointestinal Neoplasms, Ovarian Neoplasms
Low Dose Upper Abdominal Radiation Therapy (LD-UART) + Gemcitabine in Patients With Advanced, Unresectable Pancreatic Cancer (PC)
The purposes of this study are: 1. To assess the maximum tolerated dose of low-dose UART(Upper Abdominal Radiation Therapy ) or WART(Whole Abdominal Radiation Therapy) given in combination with standard fixed dose-rate…
- Trial name
- GCC0319 (NCT00390182)
- Testing
- Gemcitabine
- Where
- 2 sites in United States, Canada
- Volunteers
- 38 people
- Sponsor
- University of Maryland, Baltimore
Gastrointestinal Cancer
The Laparotomy Study
The depth of neuromuscular blockade (NMB) during surgery may cause a clinical dilemma between optimal surgical conditions and the risk of postoperative residual blockade.
- Trial name
- NCT02140593
- Where
- Denmark
- Volunteers
- 128 people
- Sponsor
- Herlev Hospital
Peritoneal Carcinomatosis, Gastrointestinal Cancer
Cytoreductive Surgery(CRS) Plus Hyperthermic Intraoperative Peritoneal Chemotherapy(HIPC) With Cisplatin to Treat Peritoneal Carcinomatosis From Upper Gastrointestinal Cancer
The majority of patients with upper gastrointestinal cancer, such as gastric, biliary, or pancreatic carcinoma, present with metastatic disease, and have an extremely poor survival, irrespective the type of treatment modality.
- Trial name
- NCT01116791
- Testing
- Cytoreductive Surgery (CRS) plus Hyperthermic Intraoperative Peritoneal Chemotherapy with Cisplatin (HIPC)
- Where
- Belgium
- Volunteers
- 34 people
- Sponsor
- Baki Topal
Upper Abdominal Cancer Surgery
Effect of Adding Magnesium Sulphate as Adjuvant to Bupivacaine in Ultrasound Guided External Oblique Intercostal Plane Block in Upper Abdominal Cancer Surgery.to Assess the Total Postoperative Opioid Consumption in the First 24 h and Evaluate Post Operative VAS Score
double blind randomized controlled trial will be conducted on upper abdominal cancer surgery cases to study the effect of Adding Magnesium Sulphate as Adjuvant to Bupivacaine in Ultrasound Guided External Oblique Intercostal…
- Trial name
- NCT06677827
- Testing
- Bupivacaine, Magnesium Sulfate and Bupivacaine 0.125%
- Volunteers
- 68 people
- Sponsor
- Assiut University
Cancer Pain
Transdiscal vs Paravertebral Neurolytic Splanchnic Nerve Block for Upper Abdominal Cancer Pain
This study aims to compare the efficacy of fluoroscopy-guided paravertebral (PV) and transdiscal (TD) approaches for splanchnic nerve neurolysis in patients with upper abdominal cancer-related pain (e.g., gastric, pancreatic, and…
- Trial name
- NCT07445386
- Testing
- transdiscal splanchnic neurolysis, paravertebral splanchnic neurolysis
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Ankara Etlik City Hospital
Breast Cancer Recurrent
Breast Cancer Recurrence - the Accuracy of Dual-time PET/CT
The purpose of this study is to elucidate the value of dual-time-point PET/CT in the recurrence of breast cancer and to determine whether the method is better than the modalities used in the standard work up.
- Trial name
- BREAC-AUT (NCT01552655)
- Testing
- Dual-time PET/CT (low-dose)
- Where
- Denmark
- Volunteers
- 101 people
- Sponsor
- Odense University Hospital
Pain Relief in Upper Abdominal Cancer Surgeries
Analgesic Efficacy of Erector Spinae Infusion Versus Thoracic Epidural for Patients With Upper Abdominal Cancer Surgeries
Epidural analgesia is considered by many to be the reference standard which has been shown to reduce the intraoperative surgical stress response.
- Trial name
- NCT04776109
- Testing
- erector spinae block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Abdominal Cancer
Inhale and Exhale Breath Holds to Improve the Radiation Therapy Accuracy in People With Upper Abdominal Cancers
This is a prospective quality improvement study. The INEX RT P study will prospectively evaluate INEX RT R that optimizes radiation dose delivery to the target while minimizing dose to critical organs at risk (OAR) by treating…
- Trial name
- INEX-RT P (NCT07594691)
- Testing
- Simulation and treatment imaging
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University Health Network, Toronto
Barrett Esophagus, Gastroesophageal Reflux
Demographics and Findings of Upper Endoscopy Patients
The purpose of this study is to evaluate the demographics, patients symptoms, and findings during endoscopy. Patients presenting for an endoscopy procedure to the KCVA GI endoscopy suite, will be asked to fill out questionnaires…
- Trial name
- NCT00576992
- Where
- United States
- Volunteers
- 1,177 people, healthy volunteers welcome
- Sponsor
- Midwest Biomedical Research
Tumor Motion, "Continuous Positive Airway Pressure"
Evaluation of Continuous Positive Airway Pressure for Tumor Motion Management in Radiotherapy
This is a clinical study on patients to compare the effects of CPAP on lung volume diaphragm motion, heart position and tumor motion compared to free breathing.
- Conditions
- Tumor Motion, "Continuous Positive Airway Pressure", Lung Cancer, Breast Cancer
- Trial name
- NCT02324530
- Testing
- Continuous positive airway pressure (CPAP)
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Sheba Medical Center
Upper Abdominal Cancer Pain, Pancreatic Cancer
Outcomes of Fluoroscopy-Guided Transdiscal Splanchnic Nerve Neurolysis for Upper Abdominal Cancer Pain.
The goal of this prospective study is to learn whether fluoroscopy-guided transdiscal splanchnic nerve neurolysis can safely reduce severe upper abdominal cancer pain in adults with pancreatic, gastric, or hepatobiliary cancer.
- Conditions
- Upper Abdominal Cancer Pain, Pancreatic Cancer, Gastric Cancer, Hepatobiliary Cancer
- Trial name
- NCT07825870
- Testing
- Chemical Neurolysis
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Sahiwal medical college sahiwal
Prostate Cancer, Head and Neck Cancers
A Pilot Study Evaluating the Effect of 2D Antiscatter Grids on CBCT Image Quality
This is Pilot study that investigates the CBCT(Cone beam computed tomography) image quality improvement provided by the 2D antiscatter grid technology.
- Conditions
- Prostate Cancer, Head and Neck Cancers, Upper Abdomen Cancers
- Trial name
- NCT04565457
- Testing
- Research CBCT
- Where
- 2 sites in United States
- Volunteers
- 43 people
- Sponsor
- University of Colorado, Denver
Thoracic Neoplasm, Liver Cancer
Mechanically-assisted Ventilation in the Treatment of Moving Tumours With Photon and Proton Therapies
Mechanical ventilation can be used to impose a completely regular pattern of breathing frequency and inflation volume on the patient for as long as required.
- Conditions
- Thoracic Neoplasm, Liver Cancer, Ventilator Lung, Radiotherapy; Complications
- Trial name
- NCT03226925
- Testing
- Non-invasive mechanically-assisted ventilation, Dynamic MRI acquisition, Planning 4D-CT
- Where
- Belgium
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Cancer Pain
Coeliac Plexus Neurolysis Versus Splanchnic Nerve Neurolysis
Pain is prevalent among patients with gastrointestinal cancers. Standard procedures such as coeliac plexus neurolysis (CPN) is effective in reducing pain, opioid requirement and related side effects for pancreatic cancer cases.
- Trial name
- NCT05541211
- Testing
- Coeliac plexus neurolysis, Splanchnic nerve neurolysis
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- The University of Hong Kong
Tumor of Pancreas, Surgical Blood Loss
Enucleation of Pancreatic Tumor by Blocking Abdominal Trunk and Superior Mesenteric Artery
Pancreatic enucleation could preserve more healthy pancreatic tissues and functions with a low recurrence risk. However, conventional enucleation can cause significant intraoperative bleeding, especially in which tumors in the…
- Trial name
- NCT06164769
- Testing
- blocking both the abdominal trunk and superior mesenteric artery in the pancreatic enucleation
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Zhejiang University
Abdominal Pain
Efficacy Study of Acupuncture to Treat the Upper Abdominal Pain of Cancer Patients
This study is to investigate the effectiveness of acupuncture for alleviating the upper abdominal pain of cancer patients
- Trial name
- NCT01913574
- Testing
- Acupuncture, Neurolytic celiac plexus block (NCPB)
- Where
- South Korea
- Volunteers
- 14 people
- Sponsor
- Daegu Catholic University Medical Center
Upper Abdominal Malignancies, Upper Gastrointestinal Cancer
Comparison of CT-Guided Celiac Plexus Neurolysis and Pharmacotherapy
After enrolment, patients were randomly assigned to two groups by means of a lottery procedure, whereby each patient blindly chose one of two labelled slips, resulting in group assignment to receive.
- Trial name
- NCT07761650
- Testing
- CT-guided celiac plexus neurolysis, Standard pharmacotherapy
- Where
- Pakistan
- Volunteers
- 110 people
- Sponsor
- Mayo Hospital Lahore
Any Solid Malignancies of Any Tissue Origin (Except for Small Cell Lung Cancer) Involving the Upper Abdomen and Thorax
Novel Optical Surface Image Guidance System for Beam-Gated Online Adaptive SBRT Delivery in Mobile Lower Lung and Upper Abdominal Malignancies
Motion during radiation therapy can be categorized as inter-fraction (changes in anatomy that occur between treatment days) and intra-fraction (changes that occur during the "beam on" window of treatment delivery).
- Trial name
- NCT05030454
- Testing
- ETHOS, CT-guided stereotactic adaptive radiotherapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Washington University School of Medicine
Extrahepatic Bile Duct Cancer, Nausea
Aprepitant in Preventing Nausea and Vomiting in Patients Undergoing Chemotherapy and Radiation Therapy for Pancreatic Cancer
This pilot clinical trial is studying how well aprepitant works in preventing nausea and vomiting in patients undergoing chemotherapy and radiation therapy for pancreatic cancer.
- Conditions
- Extrahepatic Bile Duct Cancer, Nausea, Vomiting, Stage II Pancreatic Cancer
- Trial name
- NCT01534637
- Testing
- aprepitant, gemcitabine hydrochloride, capecitabine
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Wake Forest University Health Sciences