Clinical trials: Upper Extremity Function, open to volunteers
Hand Injuries, Forearm Injuries
Perceived Ability and Hand Function
Patient-reported outcome measures, which are subjective by nature, need to be correlated with clinician-administered professional measurements as a further step toward expanding their clinical utility.
- Trial name
- NCT07388303
- Testing
- Questionnaire and Physical Exam
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Pamukkale University
Amputation, Amputation, Traumatic
Effects of Myoelectric Channel Count and Targeting for Upper Limb Prosthetic Control
The goal of this clinical trial is to systematically evaluate whether or not two commonly held fundamental assumptions for pattern recognition control translates to functional performance when tested on individuals aged 18 years…
- Conditions
- Amputation, Amputation, Traumatic, Amputation, Congenital, Prosthesis User
- Trial name
- NCT07011420
- Testing
- Experimental socket with 4 untargeted channels active, Experimental socket with 8 untargeted channels active, Experimental socket with up to 16 untargeted channels active
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- Liberating Technologies, Inc.
Functional Constipation (FC)
The Beneficial Effect on the Bowel Function of a Food Supplement Based on Sea Buckthorn (Hippophae Rhamnoides L.) Extract in Subjects With Primary Functional Constipation
The study will aim to evaluate the efficacy and tolerability of a supplementation with Sea Buckthorn (Hippophae rhamnoides L.) at two different dosages for the management of the balance of intestinal function in subjects with…
- Trial name
- NCT07082673
- Testing
- Sea Buckthorn (Hippophae rhamnoides L.) botanical extract 500 mg., Sea buckthorn (Hippophae rhamnoides L.) 1500 mg.
- Where
- Italy
- Volunteers
- 135 people
- Sponsor
- ISTITUTO FARMOCHIMICO FITOTERAPICO: EPO SRL
Distal Radius Fracture
Satisfaction and Recovery After Distal Radius Fracture
Distal radius fracture is the most common fracture in Sweden, but little is known about the patient's experience of pain and hand function during the first three months after the injury.
- Trial name
- NCT05818241
- Testing
- Treatment of fracture by forearm cast, Surgical treatment of fracture
- Where
- 2 sites in Sweden
- Volunteers
- 300 people
- Sponsor
- Sahlgrenska University Hospital
Epileptic Encephalopathy, SCN2A Encephalopathy
A Clinical Trial of Elsunersen in Pediatric SCN2A-DEE to Assess Efficacy and Safety
A Multi-Center, Single-Arm Clinical Trial to Investigate the Efficacy and Safety of Elsunersen in Pediatric Participants with Early Onset SCN2A Developmental and Epileptic Encephalopathy
- Trial name
- NCT07019922
- Testing
- 1mg elsunersen, 0.5mg elsunersen
- Where
- 10 sites in United States, Brazil and 2 more
- Volunteers
- 40 people
- Sponsor
- Praxis Precision Medicines
Spinal Cord Injury, Quadriplegia/Tetraplegia
Home-Based Digital Rehabilitation Program Optimized With Transcutaneous Spinal Cord Stimulation for Upper Limb Functional Enhancement in Tetraplegia (HOPE): A Safety, Efficacy, and Feasibility Study
Individuals with chronic cervical spinal cord injury (SCI) and tetraplegia commonly experience persistent impairment in upper limb function, leading to reduced independence and quality of life.
- Trial name
- HOPE (NCT07438353)
- Testing
- Home-based digital rehabilitation programme with tSCS
- Where
- Singapore
- Volunteers
- 9 people
- Sponsor
- Singapore General Hospital
Obstructive Sleep Apnea, Sleep Apnea
Validity and Reliability of the 6-Minute Pegboard and Ring Test (6PBRT) in Adults With Obstructive Sleep Apnea Syndrome
Obstructive sleep apnea (OSA) is a common sleep-related breathing disorder characterized by recurrent upper airway obstruction during sleep, leading to intermittent hypoxia and sleep fragmentation.
- Trial name
- NCT07465874
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mardin Artuklu University
Stroke
Proximal Priority Versus Distal Priority Robotic Priming Effects in Patients With Chronic Stroke
This is a single-blind randomized comparative efficacy study involving 54-72 participants with chronic stroke. Participants will be randomized into proximal priority robotic group or distal priority robotic group and receive 18…
- Trial name
- NCT04446273
- Testing
- Bi-Manu-Track
- Where
- 4 sites in Taiwan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Diabetic Peripheral Neuropathy
Efficacy of a Structured Multisensory Re-education Program on Sensory Function and Upper Limb Sensorimotor Performance in Individuals With Diabetic Peripheral Neuropathy.
Diabetic Peripheral Neuropathy (DPN) is a common complication of diabetes that can cause impairments in sensation, dexterity, and upper-limb function.
- Trial name
- SENS-UL (NCT07670598)
- Testing
- Structured Multisensory Re-education Program
- Volunteers
- 59 people
- Sponsor
- Imam Abdulrahman Al Faisal Hospital
Spinal Cord Injuries
Time-effect of FEST+TST in the Upper-extremity Rehabilitation of Individuals with Traumatic SCI
The purpose of this study is to investigate whether the timing of delivery of functional electrical stimulation therapy in combination with task-specific training (FEST+TST) following spinal cord injury (SCI) influences…
- Trial name
- NCT04910204
- Testing
- FES Therapy combined with task-specific training (FEST+TST)
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- University Health Network, Toronto
Female, Age ≥ 18 Years Old, No Previous Systemic Treatment for the Current Disease, Including Surgery, Antitumor Radiochemotherapy/Immunotherapy
Neoadjuvant Chemotherapy Plus Cadonilimab for Locally Advanced Cervical Cancer
Main Purpose of this study is to determine the efficacy and safety of Cadonilimab combined with chemotherapy (cisplatin) for locally advanced cervical cancer.
- Conditions
- Female, Age ≥ 18 Years Old, No Previous Systemic Treatment for the Current Disease, Including Surgery, Antitumor Radiochemotherapy/Immunotherapy, ECOG Score of 0-1, Histologically Confirmed Cervical Cancer, FIGO Stage IB3, IIA2, IIB, IIIC, and Assessed by the Researcher as Resectable Lesion
- Trial name
- NCT07104149
- Testing
- Cadonilimab combined with cisplatin
- Where
- China
- Volunteers
- 29 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Stroke
Investigation of the Effects of Task-Oriented Circuit Training on Upper Extremity Motor Function in Stroke Patients
Stroke is a disease characterized by symptoms such as weakness on one side of the body, speech impairment or inability to understand spoken language, vision problems, and loss of balance, walking, and coordination, resulting from…
- Trial name
- NCT07428161
- Testing
- Exercise-TOCT, Exercise- standard
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Gazi University
Post-stroke Upper Limb Hemiparesis, Repetitive Transcranial Magnetic Stimulation (rTMS)
Repetitive Transcranial Magnetic Stimulation Combined With Bimanual Therapy for Upper Limb Stroke Rehabilitation
The goal of this clinical trial is to evaluate whether combining repetitive transcranial magnetic stimulation (rTMS) with machine-assisted bimanual therapy (BT) can improve upper limb function in stroke patients.
- Conditions
- Post-stroke Upper Limb Hemiparesis, Repetitive Transcranial Magnetic Stimulation (rTMS), Bimanual Therapy, Neuromodulation
- Trial name
- NCT07054424
- Testing
- Conventional occupation therapy, stretching exercise, rTMS
- Where
- Taiwan
- Volunteers
- 54 people
- Sponsor
- Chang Gung Memorial Hospital
Distal Radius Fracture, Colles Fracture
Wrist Injury Strengthening Exercise (WISE) Versus Usual Care Advice for Improving Pain and Function
The goal of this clinical trial is to find out whether a therapist-guided exercise program helps people aged 50 and older recover better, in terms of pain and function, after a wrist fracture, compared to the usual care advice…
- Conditions
- Distal Radius Fracture, Colles Fracture, Wrist Fracture, Wrist Fractures
- Trial name
- WISE-DK (NCT07538323)
- Testing
- Supervised Exercise, Usual Care
- Where
- Denmark
- Volunteers
- 588 people
- Sponsor
- University of Aarhus
Asthma
Depemokimab Asthma Imaging and Bronchoscopy Sub-Study
Asthma is a chronic condition marked by narrowed and swollen airways due to inflammation leading to recurring symptoms that can vary and worsen unpredictably.\xa0The purpose of this study is to assess how depemokimab, a…
- Trial name
- NCT06979323
- Testing
- Depemokimab
- Where
- 50 sites in United States, Belgium and 10 more
- Volunteers
- 150 people
- Sponsor
- GlaxoSmithKline
Stroke, Post Stroke Hand Rehabilitation
Effects of Neuromuscular Electrical Stimulation With Neural Mobilization in Stroke Patients
The goal of this clinical trial is to learn if neuromuscular electrical stimulation combined with upper limb neural mobilization works to improve hand grip and upper limb function in post-stroke patients.
- Trial name
- NCT07629908
- Testing
- Conventional physical therapy, Neuromuscular Electrical Stimulation
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Cerebral Palsy, Hemiplegia
Functional Benefits of Multisite Upper Limb Surgery in Children With Unilateral Cerebral Palsy (RETRO-CHIRc)
This retrospective study evaluates the functional impact of individualized multisite neuro-orthopedic upper limb surgery in children with unilateral cerebral palsy (hemiplegic CP).
- Trial name
- RETRO-CHIRc (NCT07891078)
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Centre Médico-Chirurgical de Réadaptation des Massues Croix Rouge Française
Pancreatic Adenocarcinoma Locally Advanced
Cryoablation Combined With the Dual-Function Antibody PD-1/CTLA-4 for the Treatment of LAPC Following Failure of First-Line AG Therapy
The study explores the efficacy and safety of cryoablation combined with the dual-function antibody PD-1/CTLA-4 (Apalulizumab) for the treatment of locally advanced pancreatic cancer following failure of first-line AG therapy.
- Trial name
- NCT07306286
- Testing
- Cryoablation, Dual-Function Antibody PD-1/CTLA-4
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Ruijin Hospital
Cerebral Palsy (CP)
Effect of a Humanoid Robot With Virtual Reality Games to Train Arm Function in Children With Cerebral Palsy - THRIVE Trial
About 60% of children with cerebral palsy (CP) have impaired arm function. Improving arm function requires hundreds of repetitions per day, which is impossible in a single clinical visit.
- Trial name
- THRIVE (NCT06881407)
- Testing
- Robot, Virtual Reality
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Georgia State University
Stroke, CVA
COgnitive-somatoSensory-MOtor Training to Improve Arm and Hand Function After Stroke (iCOSMO)
The iCOSMO study investigates the feasibility and beneficial effects of an intervention combining sensation, motor and cognition to improve arm and hand function after chronic stroke.
- Conditions
- Stroke, CVA, Cerebrovascular Accident
- Trial name
- iCOSMO (NCT06498011)
- Testing
- Home Graded Repetitive Arm Supplementary Program (GRASP), integrated Somatosensory-MOtor training using a COgnitive approach(iCOSMO)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University Health Network, Toronto