Clinical trials: Upper Extremity Trauma, open to volunteers
Traumatic Brain Injury, Upper Extremity
Transcutaneous Auricular Vagus Nerve Stimulation to Improve Upper Extremity Recovery After Traumatic Brain Injury
Upper extremity weakness, impaired coordination, reduced dexterity, and limited arm and hand use may continue after TBI. Repetitive, task-specific rehabilitation may improve function, but recovery can remain incomplete.
- Trial name
- taVNS (NCT07867015)
- Testing
- taVNS, FTP
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Craig Hospital
Spinal Cord Injury Cervical
Noninvasive Spinal Stimulation to Restore Hand Function in Children With Spinal Cord Injury
The main goal of this pilot study is to find the best ways to use transcutaneous spinal cord stimulation (scTS) to improve hand function in children with spinal cord injuries (SCI).
- Trial name
- NCT06489106
- Testing
- Activity based upper extremity training with and without stimulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Louisville
User of an Upper Limb Assistance Device, User Experience
Impact Study on Users of Upper Limb Assistive Devices
This impact study of upper limb (UL) assistance devices is part of the Exploratory PEPR O2R "Robotic assistance for human movements." The integrated project PI3 "ASSISTMOV," composed of a multidisciplinary team in engineering and…
- Conditions
- User of an Upper Limb Assistance Device, User Experience, Post-stroke, Spinal Cord Injury
- Trial name
- AMUSE (NCT07429188)
- Testing
- interviews and questionnaires
- Where
- 2 sites in France
- Volunteers
- 150 people
- Sponsor
- Association APPROCHE
Pain, Procedural, Analgesia
Procedural Sedation and Analgesia for Treatment of Adults With Fractures and Dislocations in the Emergency Department
The goal of this observational study is to evaluate the effectiveness and safety of different procedural sedation and analgesia methods used for adults with painful fractures requiring reduction treatment in the emergency…
- Conditions
- Pain, Procedural, Analgesia, Extremity Injury, Patient Satisfaction
- Trial name
- PAINEX (NCT07314450)
- Testing
- Usual Care
- Where
- 3 sites in Denmark
- Volunteers
- 200 people
- Sponsor
- Region Zealand
Traumatic Brain Injury
Multi-Arm Multi-Stage Adaptive Platform Trial (APT) for the Acute Treatment of Traumatic Brain Injury
The purpose of this study is to determine if experimental drug treatment improves recovery after TBI as compared to a control (placebo) group. Changes in recovery will be measured throughout the study.
- Trial name
- APT-TBI-01 (NCT05826912)
- Testing
- Atorvastatin Calcium, Minocycline Hydrochloride, Candesartan Cilexetil
- Where
- 18 sites in United States
- Volunteers
- 672 people
- Sponsor
- University of California, San Francisco
Brain Injuries, Focal
VR Versus Task-Oriented Circuit Training on UL Sensorimotor in Children With Immature Brain Injury
To investigate and compare the effect of virtual reality and task-oriented circuit training on pinch grip and quality of life in children with with immature brain injury.
- Trial name
- NCT07827365
- Testing
- Virtual reality, Task-oriented circuit training
- Volunteers
- 44 people
- Sponsor
- October 6 University
Hemorrhagic Stroke, Aneurysm, Intracranial
The Use of p48/64 MW HPC Flow Modulation Device in the Treatment of Wide-necked Intracranial Aneurysms
To determine safety and effectiveness of the p48 MW HPC and p64 MW HPC Flow Modulation Device in the treatment of wide-necked intracranial aneurysms.
- Conditions
- Hemorrhagic Stroke, Aneurysm, Intracranial, Saccular Aneurysm, Fusiform Aneurysm
- Trial name
- PIANO (NCT07143019)
- Testing
- Flow diversion
- Where
- 25 sites in United States
- Volunteers
- 214 people
- Sponsor
- phenox Inc.
Nasopharyngeal Carcinoma (NPC), Radiation Injuries
Pseudomembrane Removal for Post-RT Nasopharyngeal Necrosis
This study aims to evaluate the effectiveness and safety of endoscopic nasopharyngeal pseudomembrane removal in reducing radiation-induced nasopharyngeal necrosis in patients with recurrent nasopharyngeal carcinoma who have…
- Conditions
- Nasopharyngeal Carcinoma (NPC), Radiation Injuries, Necrosis
- Trial name
- EPoRN (NCT07552883)
- Testing
- Endoscopic Nasopharyngeal Pseudomembrane Removal
- Volunteers
- 40 people
- Sponsor
- Jiangxi Provincial Cancer Hospital
Distal Radius Fracture
Functional Outcome After EPL-rupture After Distal Radius Fracture
Rupture of the extensor pollicis longus, (EPL) is a common complication after distal radius fractures. A rupture prevents the thumb extension, which in turn has a negative impact on hand function.
- Trial name
- NCT05264675
- Testing
- primary suture, EIP-transfer
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Vastra Gotaland Region
Wrist Fractures, Distal Radius Fractures
Unilateral Training of the Uninjured Limb on Clinical Outcomes in Patients with Surgically Treated Radius Fracture
The objective will be to determine the effectiveness of adding unilateral upper limb postoperative training to standard rehabilitation compared to standard rehabilitation on maximum grip strength and manual dexterity in patients…
- Trial name
- NCT06698367
- Testing
- Standard rehabilitation, Unilateral high-intensity strength exercise, Unilateral mobility exercises
- Where
- Chile
- Volunteers
- 52 people
- Sponsor
- Universidad Catolica de Temuco
Shoulder Injuries and Disorders, Elbow Injuries and Disorders
Cross-Cultural Adaptation, Validity, and Reliability of the Functional Arm Scale for Throwers (FAST) in Throwing Athletes
The Functional Arm Scale for Throwers (FAST) is a patient-reported outcome measure that assesses upper extremity function in overhead throwing athletes.
- Conditions
- Shoulder Injuries and Disorders, Elbow Injuries and Disorders, Athletic Injuries
- Trial name
- NCT07893899
- Where
- Turkey (Türkiye)
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Elif Turgut
Stroke, Spinal Cord Injuries and Disorders
Spinal Cord Stimulation Combined With Physical Therapy in Post-Stroke Upper-Limb Motor Hemiparesis
This study plans to use systems that have been developed by Medtronic to investigate the use of cervical spinal cord stimulation to treat adults with upper limb hemiparesis resulting from a stroke.
- Conditions
- Stroke, Spinal Cord Injuries and Disorders, Hemiparesis After Stroke
- Trial name
- NCT07153536
- Testing
- Spinal Cord Stimulator (Medtronic Inceptiv™ System), Physical Therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Marco Capogrosso
Hand Injuries, Forearm Injuries
Perceived Ability and Hand Function
Patient-reported outcome measures, which are subjective by nature, need to be correlated with clinician-administered professional measurements as a further step toward expanding their clinical utility.
- Trial name
- NCT07388303
- Testing
- Questionnaire and Physical Exam
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Pamukkale University
Spinal Cord Injury Cervical, Spinal Cord Injury, Acute
Upper Limb Rehabilitation Using Non-invasive Spinal Cord Stimulation
The goal of this RCT study is to evaluate if combining activity-based therapy (ABT) with transcutaneous spinal cord stimulation (tSCS) can improve recovery of arm and hand movement in people with cervical spinal cord injury…
- Conditions
- Spinal Cord Injury Cervical, Spinal Cord Injury, Acute, Spinal Cord Injury (Quadraplegia)
- Trial name
- CIME_upperlimb (NCT07361627)
- Testing
- Protocol 2: Combination of activity-based therapy and facilitatory transcutaneous spinal cord stimulation
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal
Tennis Elbow, Health Adult Subjects
Assessment of Pressure Pain Threshold (PPT) and Conditioned Pain Modulation (CPM) After Effect in Patients With and Without Tennis Elbow (TE)
This study at Hashemite University looks at how people with and without tennis elbow (AKA lateral elbow tendinopathy) feel pressure pain and how their bodies briefly "turn down" pain after a cold stimulus.
- Conditions
- Tennis Elbow, Health Adult Subjects, Lateral Elbow Tendinopathy (Tennis Elbow), Pressure Pain Threshold (PPT)
- Trial name
- NCT07178288
- Testing
- Physiological/measurement-validation study
- Where
- Jordan
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- The Hashemite University
Fracture Forearm, Radius Distal Fracture
Distal Radial Fractures in Adult Patients: 4 Weeks Versus 6 Weeks of Cast Immobilization
Post-intervention outcomes comparing casting in distal radius fractures of four weeks versus six weeks.
- Trial name
- NCT07234370
- Testing
- Short Arm Cast for Distal Radius Fracture for four weeks, Short Arm Cast for Distal Radius Fracture for six weeks
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Liaquat National Hospital & Medical College
Spinal Cord Injury Cervical
Non-Invasive Neuromodulation for Upper Extremity Function in Spinal Cord Injury: A Crossover Trial
This study explores two promising therapies for restoring arm and hand function in people with chronic cervical spinal cord injury (SCI), a condition that affects independence and quality of life.
- Trial name
- NCT06903416
- Testing
- Transcutaneous Cervical Spinal Cord Stimulation, Paired Corticospinal Motoneuronal Stimulation, Functional Task Practice
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of Alberta
Pressure Ulcers (Hospital-acquired Pressure Injuries)
Sacrum Pressure Injury Prevention Study Using ALLEVYN◊ Complete Care in Adults at Risk of Developing Hospital-acquired Pressure Injuries in Critical Care Units
The purpose of this study is to investigate the use of ALLEVYN◊ COMPLETE CARE Sacrum dressing for the prevention of hospital-acquired pressure injuries in adults.
- Trial name
- PACCT (NCT07849387)
- Testing
- ALLEVYN◊ COMPLETE CARE Sacrum
- Where
- 3 sites in United States
- Volunteers
- 330 people
- Sponsor
- Smith & Nephew, Inc.
Peripheral Nerve Injury Upper Limb
Ultrasound Guided Placental Growth Factor Vs Platelet Rich Plasma Injection in Peripheral Nerve Injury: an Interventional Study
The goal of this clinical trial is to learn if placental growth factor injection and platelet rich plasma injection works to treat peripheral nerve injury in adults.
- Trial name
- NCT06638008
- Testing
- perineural injection
- Volunteers
- 75 people
- Sponsor
- Assiut University
Complex Regional Pain Syndrome Type I (CRPS-I), Distal Radius Fracture
ESWT for CRPS-I After Distal Radius Fracture
Complex regional pain syndrome type I (CRPS-I) can develop after a distal radius fracture and may cause persistent pain, swelling, limited wrist and hand movement, and difficulty using the affected upper limb.
- Trial name
- CRPS-ESWT (NCT07807852)
- Testing
- Active ESWT will be applied once weekly for a total of five sessions to the affected distal forearm, wrist, and painful soft-tissue areas.Associated Arm: Standard Rehabilitation + Active ESWT, Standard Rehabilitation Program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Dilek ün oguzhanasilturk