Clinical trials: Upper Extremity Tremor
Upper Extremity Tremor
123I-ALTROPANE® Reference Image Acquisition in Subjects With Diagnostically Uncertain Tremor
This study is designed to obtain an imaging training set that will be used to evaluate images in future trials. Currently, no radiopharmaceutical diagnostic imaging agent has been approved by the FDA in the U.S.
- Trial name
- AIM (NCT00596908)
- Where
- 7 sites in United States
- Volunteers
- 54 people
- Sponsor
- Alseres Pharmaceuticals, Inc
Essential Tremor
directSTIM™ Deep Brain Stimulation System Post-Market Clinical Follow-up Study on Essential Tremor
This is a prospective, multi-center, single arm post-market clinical follow-up study. The present study investigates a product authorized on the European market that will be used per its intended use, and all procedures involved…
- Trial name
- NCT05795218
- Testing
- Deep Brain Stimulation
- Where
- 5 sites in Germany
- Volunteers
- 21 people
- Sponsor
- Aleva Neurotherapeutics SA
Tremor
Electrophysiological Study of the Effects of Limb Cooling on Essential Tremor
To determine the effects of upper limb forearm cooling on Essential Tremor upper limb tremor using a more practical method of limb cooling through a forearm cold pack.
- Trial name
- NCT01093027
- Testing
- 15 - 30, 30 - 15
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
PARKINSON DISEASE (Disorder), Tremor
Effect of Kinesiotaping on Tremor in People With Parkinson's Disease
The goal of this clinical trial is to learn whether adding kinesiotaping to a strengthening and stretching home-exercise program can reduce hand tremor and improve hand function in people with Parkinson's disease.
- Conditions
- PARKINSON DISEASE (Disorder), Tremor, Tremor Associated With Tremor Dominant Parkinson's Disease
- Trial name
- NCT07555847
- Testing
- Therapeutic Kinesiotaping, Home Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Essential Tremor
Assessment of the Safety and Efficacy of the Felix NeuroAI Wristband in Essential Tremor
The goal of this clinical study is to compare Felix NeuroAI Wristband and sham device in patients with essential tremor. The main question it aims to answer is: Is Felix a safe and efficacious treatment for patients with…
- Trial name
- TRANQUIL (NCT06235190)
- Testing
- Felix NeuroAI Wristband
- Where
- 12 sites in United States, China
- Volunteers
- 125 people
- Sponsor
- Fasikl Inc.
Essential Tremor of the Upper Limb
A Study to Investigate the Efficacy and Safety of NT 201 (Botulinum Toxin) Compared With Placebo for the Treatment of Adult Participants With Essential Tremor in the Arm
The purpose of this study is to determine whether a single treatment with NT 201 (botulinum toxin) is superior to placebo (no medicine) for one-sided treatment of essential tremor in the motor-dominant arm (Unilateral Period).
- Trial name
- NCT04766723
- Testing
- NT 201
- Where
- 14 sites in United States, Canada and 1 more
- Volunteers
- 78 people
- Sponsor
- Merz Pharmaceuticals GmbH
Tremor, Action Tremor
Deep Brain Stimulation (DBS) for the Suppression of Tremor
The purpose of the proposed study is to demonstrate the safety and efficacy of the ANS Totally Implantable Deep Brain Stimulation System in the VIM nucleus of the thalamus implanted for the treatment of tremor due to essential…
- Conditions
- Tremor, Action Tremor, Essential Tremor, Tremor, Limb
- Trial name
- NCT02087046
- Testing
- ANS Totally Implantable Deep Brain Stimulation System
- Where
- 12 sites in United States
- Volunteers
- 127 people
- Sponsor
- Abbott Medical Devices
Essential Tremor
The Relationship of Muscle Strength With Functional Skills in Geriatric Individuals With Essential Tremor
Essential tremor is one of the most common movement disorders in the world and is characterized by postural and/or kinetic tremor.
- Trial name
- NCT05244863
- Testing
- Test
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Tremor, Limb
A Cross Over Pilot Study of Abobotulinum Toxin A (Dysport) as a Treatment for Task-dependent Upper Limb Tremor
Task-dependent upper limb tremor is a disorder that frequently impairs patients' function and quality of life. Few studies exist that quantify the improvements in motor performance and disability with botulinum toxin…
- Trial name
- NCT03136341
- Testing
- Abobotulinum toxin A
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- David M. Simpson
Parkinsonian Syndromes
Two Separate But Identical Studies Evaluating the Safety and Efficacy of ALTROPANE® in the Use of SPECT Imaging for Upper Extremity Tremor
This will be two separate but identical studies: ALSE-A-02a, ALSE-A02b. Each study is designed to evaluate the diagnostic accuracy and safety of a single dose of 123I-ALTROPANE® in subjects with upper extremity tremor for less…
- Trial name
- POET-2 (NCT00724906)
- Testing
- 123 I - ALTROPANE®
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Alseres Pharmaceuticals, Inc
Parkinson's Disease
Kinematic-based BoNT-A Bilateral Upper Limb PD Therapy
The primary objective is to study the efficacy of botulinum toxin type A (BoNT-A) injected via kinematic parameters in the treatment of unilateral/bilateral upper extremity tremor in Parkinson's disease (PD) tremor.
- Trial name
- NCT02668497
- Testing
- Botulinum Toxin Type A
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Western University, Canada
Essential Tremor
Non-Invasive Neuromodulation for Essential Tremor: Long-Term Safety and Effectiveness Study
This is a prospective, single-center, single-arm, open-label clinical study designed to evaluate the long-term efficacy and safety of non-invasive neuromodulation using transcutaneous afferent patterned stimulation (TAPS) in…
- Trial name
- NCT07774598
- Testing
- Transcutaneous Afferent Patterned Stimulation
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Ruijin Hospital
Essential Tremor, Upper Extremity Essential Tremor
Coordinated Reset Deep Brain Stimulation for Essential Tremor
Deep brain stimulation (DBS) is a surgical procedure for the treatment of Essential Tremor (ET). A novel approach to current DBS approaches is called coordinated reset DBS (CR-DBS) which uses different patterns of stimulation at…
- Trial name
- NCT05897775
- Testing
- Deep brain stimulation
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Minnesota
Spasticity, Focal Dystonia
Compare Two Guidance Techniques for Botulinum Toxin Injections for the Treatment of Limb Spasticity and Focal Dystonia
This study seeks to compare the use of ultrasound and electrophysiologic techniques to target muscles for the treatment of spasticity and focal dystonia of the limbs.
- Conditions
- Spasticity, Focal Dystonia, Tremor, Limb
- Trial name
- NCT02334683
- Testing
- Electrical stimulation, Ultrasound
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Essential Tremor
Kinematic-based BoNT-A Injections for Bilateral ET
The primary objective is to study the efficacy of botulinum toxin type A (Xeomin®) injected utilizing kinematically-based injection parameters for the treatment of upper extremity essential tremor (ET).
- Trial name
- NCT02551848
- Testing
- Botulinum toxin type A
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Western University, Canada
Parkinson Disease, Tremor
The Quality of Life in Individuals With Parkinson's Disease
This study aimed to examine the relationship of quality of life with tremor severity and upper limb functionality in individuals with Parkinson's Disease.
- Conditions
- Parkinson Disease, Tremor, Functionality
- Trial name
- NCT05906693
- Testing
- Quality of life, Upper limb functionality, Grip and pinch strength
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Pamukkale University
Upper Limb Tremor Invalidating
Evaluation the Effect of Muscle Functional Electrical Stimulation in the Upper Limb Tremor Invalidating
The main objective of this study is to identify the superficial muscle groups involved in gene-related tremor and assess the reduction in the intensity of the tremor after transient electrical stimulation.
- Trial name
- NCT02883738
- Testing
- tremor
- Where
- France
- Volunteers
- 35 people
- Sponsor
- University Hospital, Montpellier
Parkinson Disease, Upper Extremity Dysfunction
Effectiveness of Noninvasive Vagus Stimulation for Upper Extremity in Parkinson's Disease
Vagus nerve stimulation in the treatment of PD is a non-pharmacological intervention with the potential to improve gait, cognition, fatigue, and autonomic functions, but more evidence is needed for VSS in the treatment of PD.
- Conditions
- Parkinson Disease, Upper Extremity Dysfunction, Tremor
- Trial name
- NCT05456451
- Testing
- noninvasive vagus nerve srimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 5 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Parkinson Disease, Tremor
Action Observation Therapy and Mirror Therapy in Parkinson's Disease
Small muscles of the hand are affected due to involuntary movements and slowing of voluntary movements seen in Parkinson's disease. There is a loss of fine dexterity and coordination in the hand.
- Trial name
- NCT05350709
- Testing
- mirror therapy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
PARKINSON DISEASE (Disorder)
Effect of Botulinum Toxin on Resting Tremor of the Refractory Upper Limb in Parkinsonians
Tremor is one of the most common symptoms in Parkinson Disease (PD), affecting almost 60% of patients. There is currently no specific treatment for tremor in PD, and 30% of patients develop drug-resistant tremor, making its…
- Trial name
- TOX PARK (NCT07822893)
- Where
- 2 sites in France
- Volunteers
- 39 people
- Sponsor
- University Hospital, Toulouse