Clinical trials: Upper Extremity Tremor
Action Tremor
A Controlled Comparison of Two DBS Targets for Upper Extremity Action Tremor
Action tremor of the arms can be an invalidizing symptom of diseases such as Essential Tremor, Dystonic Tremor, Parkinson's disease and Multiple Sclerosis.
- Trial name
- Tremorstim (NCT03156517)
- Testing
- Deep Brain Stimulation
- Where
- Norway
- Volunteers
- 45 people
- Sponsor
- Oslo University Hospital
Upper Limb Essential Tremor
Study of AGN-151607-DP to Assess Adverse Events and Change in Disease Activity in Adult Participants With Upper Limb Essential Tremor
Upper limb essential tremor (UL ET) is a movement disorder characterized by postural and/or kinetic tremor. It can cause difficulty with everyday tasks such as writing, pouring, and eating.
- Trial name
- NCT07673107
- Testing
- AGN-151607-DP
- Where
- 21 sites in United States, Canada
- Volunteers
- 94 people
- Sponsor
- AbbVie
Dystonic Tremor Syndrome
Factors Determining the Efficacy of Botulinum Toxin for Arm Tremor in Dystonia
Tremor occurs in up to 55% of dystonia patients, which is known as dystonic tremor syndrome (DTS). Tremor can be present in the body part affected by dystonia (dystonic tremor, DT), or an unaffected body part (tremor associated…
- Trial name
- BAT (NCT06411028)
- Testing
- Polymyography, Muscle ultrasound, (Functional) magnetic resonance imaging
- Where
- 3 sites in Netherlands
- Volunteers
- 60 people
- Sponsor
- Radboud University Medical Center
GLP-1 Concentration
Tolerance of a High Protein Nutrition Shake in Individuals on GLP-1
Determine if consuming a high protein nutrition shake reduces gastrointestinal symptoms associated with semaglutide injections.
- Trial name
- NCT07096739
- Testing
- High protein shake
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kate Farms Inc
Parkinson Disease, Tremor, Limb
Effects of a Dynamic Upper Limb Orthosis in Patients With Parkinson's Disease
This is a randomized controlled clinical trial aimed at Parkinson's disease patients. Its objective is to evaluate the effects of a dynamic upper limb orthosis to achieve maximum hand functionality, reducing tremor and rigidity
- Conditions
- Parkinson Disease, Tremor, Limb, Rigidity, Muscle
- Trial name
- NCT04815382
- Testing
- Dynamic Upper Limb Orthosis
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad de Burgos
Severe Upper Limb Tremor Refractory to Medical Therapy
Radiosurgery for Drug Resistant Invalidating Tremor
Stereotactic lesioning of thalamus and basal ganglia for treatment of tremor is a well-known procedure which, prior to the introduction of deep brain stimulation, or DBS, was usually achieved using stereotactic surgical…
- Trial name
- DB-SRS (NCT02095600)
- Testing
- Radiosurgical thalamotomy
- Where
- Italy
- Volunteers
- 6 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Tremor
Electromagnetic Tracking to Measure Tremor
Deep Brain Stimulation (DBS) is an effective treatment option for individuals with debilitating tremors that do not respond to medical therapy.
- Trial name
- NCT02641366
- Testing
- Electromagnetic tracking, Tremor kinetics after DBS, Tremor kinetics before and after DBS
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Florida
Upper Limb Essential Tremor (UL ET)
Study of BOTOX Injections to Assess Change in Disease Symptoms in Adult Participants With Upper Limb Essential Tremor
Upper limb essential tremor (UL ET) is a movement disorder characterized by postural and/or kinetic tremor. It can cause difficulty with everyday tasks such as writing, pouring, and eating, and patients also experience associated…
- Trial name
- NCT05216250
- Testing
- BOTOX
- Where
- 40 sites in United States, Canada
- Volunteers
- 174 people
- Sponsor
- AbbVie
Essential Tremor of the Upper Limbs
Botulinum Toxin A to Treat Arm Tremor
The objective of this study is to assess the efficacy and safety of a single, kinematic-analysis-based intramuscular injection of NT 201, compared with placebo, in moderate to marked essential tremor of the upper limb.
- Trial name
- NCT02207946
- Testing
- IncobotulinumtoxinA
- Where
- 6 sites in United States, Canada
- Volunteers
- 30 people
- Sponsor
- Merz Pharmaceuticals GmbH
PARKINSON DISEASE (Disorder)
Wearable for Assessing Tremor and Continuous Health in Parkinson's Disease and Essential Tremor
This prospective observational study will examine tremor and upper-limb movement in adults with Parkinson's disease or essential tremor using non-invasive wearable sensors.
- Trial name
- PD-WATCH (NCT07787299)
- Testing
- Device exposure: Wearable inertial sensor monitoring
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Heriot-Watt University
Chronic Pelvic Pain
A Novel Therapeutic Approach to Treat Chronic Pelvic Pain
To collect pilot data and assess the feasibility of a trial employing a single-arm intervention to study the effects of combined self-induced therapeutic tremors plus mindfulness on symptoms of chronic pelvic pain among women…
- Trial name
- NCT05467241
- Testing
- Self-induced therapeutic tremor (SITT) combined with mindfulness
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Tennessee Graduate School of Medicine
Stroke
Effects of Upper Extremity Rehabilitation Robot and Transcranial Direct Current Stimulation Among Patients With Stroke
Effects of upper extremity rehabilitation robot and transcranial direct current stimulation on upper extremity function among subjects with tremor after stroke
- Trial name
- NCT04055597
- Testing
- Robot and tDCS on-line
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- National Rehabilitation Center, Seoul, Korea
Essential Tremor
Upper Limb Tremor Reduction in Essential Tremor Patients
This study is designed to demonstrate the safety, tolerability, and efficacy of the Encora Therapeutics Tremor Mitigation Device in subjects with upper limb tremor caused by Essential Tremor.
- Trial name
- ULTRE (NCT06343285)
- Testing
- Encora Therapeutics Tremor Reduction Device
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- Encora, Inc.