Clinical trials: Upper Gastrointestinal Disorders
Gastrointestinal Hemorrhage, Anemia
Iron Substitution After Upper Gastro-Intestinal Bleeding
The trial is a double-blind randomized trial designed to examine whether compliant iron therapy (intravenous or oral) for 3 months after discharge increases hemoglobin levels more and faster than no treatment - in patients with…
- Trial name
- NCT00978575
- Testing
- ferricarboxymaltose, Ferrosulfate
- Where
- Denmark
- Volunteers
- 97 people
- Sponsor
- University of Aarhus
Cancer Esophagus, Pancreatic Cancer
Effect of Chewing Gum on Postoperative Bowel Function Following Upper GI Tract Cancer Surgery
Every patient undergoing surgery in the abdomen will experience temporary paralysis of bowel function. This study evaluates whether chewing gum can reduce the bowel paralysis after surgery in patients undergoing either esophageal…
- Trial name
- NCT02260128
- Testing
- Chewing gum
- Where
- Denmark
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Michael Bau Mortensen
Hepatitis C and B VIRUS Screening, Awareness and Behavior Assessment and Evaluation for All Inhabitants Above Twelve Years of Al Othmaneya Village
Effect of Implementation Of Outreach Behavioral Change Program for HCV Elimination
Elimination of hepatitis C virus (HCV) is the process of stopping sustained transmission of viral hepatitis, reducing its incidence to zero and providing access to safe, affordable and effective treatment and care for everyone.
- Trial name
- NCT03415334
- Testing
- behavioral development for change
- Volunteers
- 3,575 people, healthy volunteers welcome
- Sponsor
- National Research Centre, Egypt
Neuroendocrine Carcinoma
P:II Above-Label Octreotide-LAR With Insufficiently Controlled Carcinoid Syndrome
The primary purpose of the study is to investigate the effects of high-dose octreotide on flushing, diarrhea, and quality of life in patients whose disease-related symptoms are inadequately controlled by the maximum approved dose…
- Trial name
- NCT01886287
- Testing
- Octreotide LAR
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Appendicitis Acute
Transumbilical Laparoscopy-assisted Appendectomy
transumbilical laparoscopic-assisted appendectomy (TULAA) was reported that the operation time was shorter and the postoperative frequency of complications was not high compared to conventional laparoscopic appendectomy (CLA)…
- Trial name
- NCT04485247
- Testing
- Transumbilical Laparoscopic-Assisted Appendectomy, 3-port laparoscopic appendectomy
- Where
- South Korea
- Volunteers
- 78 people
- Sponsor
- Myongji Hospital
Gastrointestinal Cancer
Proton Radiotherapy for Upper Gastrointestinal Malignancies
The primary objectives are to determine feasibility and the acute toxicity profile of proton therapy with concurrent continuous infusion 5-FU chemotherapy.
- Trial name
- NCT01449864
- Testing
- Proton therapy
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Upper Gastrointestinal Bleeding, Proton Pump Inhibitors
The Effect of Using Preendoscopic Proton Pump Inhibitors in Upper Gastrointestinal System Bleeding on Patient Prognosis
In this study, we aimed to investigate the effectiveness of ppi use in upper gastrointestinal bleeding in patients over the age of 18 who underwent endoscopy on mortality, length of hospital stay, rebleeding, and cost.
- Trial name
- NCT05467358
- Where
- Turkey (Türkiye)
- Volunteers
- 1,100 people
- Sponsor
- Ankara City Hospital Bilkent
Upper Gastrointestinal Symptoms
Effect of AI Monitoring Blind Spots of EGD on the Inspection Time and Lesion Dection Rate
The goal of this clinic trial is to learn about the effect of AI monitoring blind spots on the inspection time to EGD. Patients are randomly assigned to undergo an EGD with or without the assistance of AI.
- Trial name
- NCT05832411
- Testing
- Endoangle
- Volunteers
- 1,672 people, healthy volunteers welcome
- Sponsor
- Renmin Hospital of Wuhan University
Gastric Cancer, Reflux Esophagitis
Preliminary Efficacy Analysis of 'λ+α' Double-Tract Reconstruction After Laparoscopic Proximal Gastrectomy
The incidence of proximal gastric cancer has increased significantly in recent years. This may be due to weight gain, alcohol consumption, gastroesophageal reflux disease (GERD), and precancerous lesions.
- Trial name
- NCT06475170
- Testing
- proximal gastrectomy combined with 'λ+α' double-tract anastomosis
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Northern Jiangsu People's Hospital
Healthy Individual
CDSS-assisted UGI Endoscopy vs. Routine Screening Endoscopy
This study aimed to find the CDSS-assisted upper GI endoscopy has clinical benefit compared to conventional routine screening upper GI endoscopy. Investigators will conduct a pilot randomized controlled study.
- Trial name
- NCT05452473
- Testing
- CDSS-assisted upper GI endoscopy, no intervention
- Where
- South Korea
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Chuncheon Sacred Heart Hospital
Obesity, Obesity, Morbid
Trans-nasal Endoscopy for Bariatric Patients
This study plans to learn if the EvoEndo Endoscopy system can be used to evaluate, provide and follow up care for upper gastrointestinal tract diseases in the bariatric population.
- Conditions
- Obesity, Obesity, Morbid, Obese, GI Disorders
- Trial name
- TNE (NCT06200961)
- Testing
- Transnasal Endoscopy, Esophagogastroduodenoscopy
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Christopher C. Thompson, MD, MSc
Esophageal Cancer, Gastric Cancer
Diagnostic Performance Indicators in Upper GI Endoscopy:PROSPERO Study
Cancers of the upper gastro-intestinal tract, including esophagus (gullet), stomach and small bowel, are amongst the deadliest malignancies.
- Conditions
- Esophageal Cancer, Gastric Cancer, Barrett Esophagus, Gastric Atrophy
- Trial name
- PROSPERO (NCT04843397)
- Volunteers
- 1,000 people
- Sponsor
- University of Cambridge
Upper Gastrointestinal Hemorrhage
Efficacy of Proton Pump Inhibitors in Cirrhotic Patients With Acute Variceal Bleeding
Acute Variceal Bleeding (AVB) in patients with liver cirrhosis is a common clinical critical disease. There is little evidence for the effect of proton pump inhibitor (PPI) use in patients with AVB, and there is no study on the…
- Trial name
- NCT05624229
- Testing
- Proton Pump Inhibitors, No Proton Pump Inhibitors
- Volunteers
- 672 people
- Sponsor
- West China Hospital
Superior Mesenteric Artery Syndrome, Somatic Symptom Disorder (DSM-5)
Fluoxetine in Refractory Superior Mesenteric Artery Syndrome by Targeting Comorbid Somatic Symptom Disorder
The goal of this interventional study is to evaluate whether fluoxetine, a selective serotonin reuptake inhibitor (SSRI), can alleviate core symptoms and reduce the need for surgical intervention in patients with refractory…
- Trial name
- NCT07115472
- Testing
- Fluoxetine
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Upper GI Bleeding
Analysis the Vocs in Upper GI Bleeding Patients
This project aims to collect the exhaled breath of patients with acute upper gastrointestinal bleeding clinically, divide them into large, small and no bleeding groups according to the results of gastroscopy, analyze the…
- Trial name
- NCT05457062
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences
Cirrhosis, Liver, Acute Upper Gastrointestinal Hemorrhage
Risk Assessment After Acute Upper Gastrointestinal Haemorrhage in Cirrhosis
In previous studies, the investigators used retrospective analysis of cases of acute upper gastrointestinal bleeding in patients with liver cirrhosis from the Fifth Medical Center of the General Hospital of Beijing PLA, China…
- Trial name
- NCT04235166
- Testing
- Current risk scores, New risk scores
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences
Acute Coronary Syndrome
Relationship of Helicobacter Pylori Eradication Therapy and Long-term Outcome in Acute Coronary Syndrome
Objective: To investigate the relationship between Helicobacter pylori (Hp) infection and the prognosis of acute coronary syndrome (ACS) in a Chinese population and to explore the significance of Hp eradication therapy in…
- Trial name
- NCT02317445
- Volunteers
- 472 people
- Sponsor
- Capital Medical University
Hypotension, Hypoxemia
Predictors of Clinically Relevant Hypotension and Hypoxemia During Propofol-Based Diagnostic Gastrointestinal Endoscopy
This prospective observational cohort study will evaluate the incidence and independent predictors of clinically relevant hypotension and hypoxemia during propofol-based diagnostic gastrointestinal endoscopy in adult patients at…
- Trial name
- PRO-GI SAFE (NCT07613073)
- Testing
- Propofol, Diagnostic gastrointestinal endoscopy
- Where
- Vietnam
- Volunteers
- 1,000 people
- Sponsor
- Bach Mai Hospital
Rectal Cancer, Colon Cancer
Contribution of Preserving the Superior Left Colic Artery to the Vascularization of the Descending Colon Prior to Colorectal Anastomosis During Left-Sided or Rectal Resections for Colorectal or Ovarian Cancer. (Revascularisation Colique)
Colorectal cancers and ovarian cancers are respectively the 2nd and 5th cause of cancer mortality in France. Surgical resection is a crucial step in the therapeutic management of colorectal cancers.
- Conditions
- Rectal Cancer, Colon Cancer, Ovarian Cancer
- Trial name
- NCT07098182
- Testing
- Clamping and restauration of arterial blood of the inferior mesenteric artery
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
Upper Gastrointestinal Bleeding
ASP (PPI_H2RA) Study-H2RA Versus PPI for the Prevention of Recurrent UGIB in High-risk Users of Low-dose ASA
Peptic ulcer bleeding associated with ASA or NSAIDs is a major cause of hospitalization in Hong Kong. The investigators previously showed that ASA or NSAIDs accounted for about half of all cases of hospitalizations for peptic…
- Trial name
- NCT01408186
- Testing
- Rabeprazole, Famotidine
- Where
- 8 sites in Hong Kong, Japan
- Volunteers
- 264 people
- Sponsor
- Chinese University of Hong Kong