Clinical trials: Upper Limb Disability
Cerebrovascular Disorders
Treatment for Movement Problems in Elderly Stroke Patients
After a stroke, many patients are left with an impaired arm. Restricting the use of the good arm may improve the use of the bad arm.
- Trial name
- NCT00059696
- Testing
- Constraint-Induced Movement Therapy
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Lateral Epicondylitis
Grip Strength or Pinch Strength in Lateral Epicondylitis
Grip strength can be decreased in lateral epicondylitis. Pinch strength is also affected in people suffering from lateral epicondylitis.
- Trial name
- NCT04206423
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Acute Stroke
Efficacy Study of an Interactive Robot for the Rehabilitation of the Upper Limb in Acute Stroke Patients
Stroke is the principal cause of permanent disability within the investigators population. This incapacity justifies an intensive and prolonged multidisciplinary rehabilitation, which can be optimized by robotics.
- Trial name
- NCT02079779
- Testing
- Robotic-assisted therapy, Classical therapy
- Where
- 3 sites in Belgium
- Volunteers
- 45 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Cancer Awareness and Prevention Education, Breast Cancer Awareness
A Single-Arm Interventional Trial of Pepper- Robot Delivered Cancer Education for Adults With Intellectual Disability
Individuals with Intellectual disability face numerous barriers to cancer education, awareness and screening, including communication challenges, anxiety, and a lack of accessible educational resources.
- Conditions
- Cancer Awareness and Prevention Education, Breast Cancer Awareness, Intellectual Disabilities (F70-F79)
- Trial name
- Pep-SMARTID (NCT07477938)
- Testing
- Robot delivered Education
- Where
- Ireland
- Volunteers
- 25 people
- Sponsor
- National University of Ireland, Galway, Ireland
Autism Spectrum Disorder, Autism
Pepea Pamoja: Cluster-Randomized Trial for Caregivers of Children With Autism in Kenya
Pepea Pamoja is a ten-session, group-based caregiver intervention designed to improve caregiver well-being and strengthen caregivers' ability to support communication and positive behavior in children with autism.
- Conditions
- Autism Spectrum Disorder, Autism, ASD
- Trial name
- NCT07259044
- Testing
- Professionally-facilitated groups, Peer-facilitated groups
- Where
- Kenya
- Volunteers
- 240 people
- Sponsor
- Indiana University
CIED Postoperative Upper Limb Stiffness and Disability
CIED Post-OR Rehabilitation
The purpose of this study is to develop a systematic rehabilitation exercise program (rehabilitation exercise routine), focusing on the rehabilitation training of the upper limb on the implantation side after transvenous cardiac…
- Trial name
- NCT07494825
- Testing
- a systematic rehabilitation exercise program (rehabilitation exercise routine), regular guidance
- Volunteers
- 600 people
- Sponsor
- Shanghai Zhongshan Hospital
Multiple Sclerosis, Primary Progressive
Hydroxychloroquine in Primary Progressive Multiple Sclerosis
The purpose of this clinical trial is to determine if HCQ in a dose of 400mg daily can prevent worsening of walking ability in people PPMS. The number of participants in this study will be 35.
- Trial name
- NCT02913157
- Testing
- Hydroxychloroquine
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- University of Calgary
Multiple Sclerosis, Secondary Progressive
Hydroxychloroquine and Indapamide in SPMS
The purpose of this clinical trial is to determine if HCQ in a dose of 400mg daily and indapamide in a dose of 2.5mg daily can help in reducing the progression of disability in people with secondary progressive multiple…
- Trial name
- NCT05013463
- Testing
- Hydroxychloroquine Pill, Indapamide Pill
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- University of Calgary
Rett Syndrome
A Novel, Regulated Gene Therapy (NGN-401) Study for Females With Rett Syndrome
This study will evaluate the efficacy and safety profiles of the investigational gene therapy, NGN-401, in females with typical Rett syndrome.
- Trial name
- NCT05898620
- Testing
- NGN-401
- Where
- 16 sites in United States, Australia and 1 more
- Volunteers
- 33 people
- Sponsor
- Neurogene Inc.
Myofascial Neck Pain, Hand Grip Strength
Core Stability vs Scapular Stabilization on Hand Grip Strength in Chronic Myofascial Neck Pain
Chronic myofascial neck pain (CMNP) is a painful non-articular musculoskeletal neck syndrome that is a persistent and prevalent with a high incidence of recurrence rate range 30-93%.Management of myofascial trigger points were…
- Conditions
- Myofascial Neck Pain, Hand Grip Strength, Pressure Pain Threshold, Trigger Point in Trapezius Muscle
- Trial name
- NCT07692126
- Testing
- Core Stability Exercise Protocol, Scapular stabilization Exercise Protocol, Traditional Physical Therapy Protocol
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Stroke, Cerebro-vascular Accident
Upper Arm Reahabilitation After Stroke and Video Game
The purpose of this study is to assess the efficiency of occupational therapy enhanced by "dedicated adaptative video games" in rehabilitation of the upper arm of stroke patients in the acute phase after their cerebro-vascular…
- Conditions
- Stroke, Cerebro-vascular Accident, Upper Arm Disability, Reaching
- Trial name
- MARGAUT (NCT01554449)
- Testing
- serious game reeducation, functional MRI
- Where
- France
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Stroke
SaeboGlove Therapy for Severe Upper Limb Disability and Severe Hand Impairment After Stroke
The study will aim to determine whether 6-weeks of using a SaeboGlove independently (with or without help from a carer) improves upper limb function (measured using the Action Research Arm Test score) in comparison to usual care…
- Trial name
- SUSHI (NCT04007315)
- Testing
- SaeboGlove therapy, Usual care
- Where
- 3 sites in United Kingdom
- Volunteers
- 110 people
- Sponsor
- NHS Greater Glasgow and Clyde
Ischemic Stroke, Chronic Stroke
Investigation of Neural Stem Cells in Ischemic Stroke
A study of stereotactic, intracerebral injection of CTX0E03 neural stem cells into patients with moderate to moderately severe disability as a result of an ischemic stroke.
- Conditions
- Ischemic Stroke, Chronic Stroke, Hemiparesis, Arm Paralysis
- Trial name
- PISCES III (NCT03629275)
- Testing
- CTX0E03 Drug Product and delivery device
- Where
- 23 sites in United States
- Volunteers
- 15 people
- Sponsor
- ReNeuron Limited
Adhesive Capsulitis
Comparative Effects of Myofascial Arm Pull and Post Isometric Relaxation Techniques in Adhesive Capsulitis
Adhesive capsulitis is defined as a condition characterized by pain and stiffness in shoulder which results in both active and passive movement loss.
- Trial name
- NCT05915689
- Testing
- Myofascial arm pull technique, post isometric relaxation technique
- Where
- Pakistan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Stroke
New Tool to Enhance Post-stroke Upper Extremity Disability
Individuals with low socioeconomic status (SES) are more likely to have a stroke, more disabled at 3 months, and less likely to be independently ambulatory.
- Trial name
- NCT05277389
- Testing
- START - Startle Adjuvant Rehabilitation Therapy
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Arizona State University
Tennis Elbow, Lateral Epicondylitis
Comparative Effects of Sustained Stretch and Mobilization With Movement in Patient With Tennis Elbow
Tennis elbow, clinically known as lateral epicondylitis, is a prevalent musculoskeletal issue marked by pain and tenderness on the outer part of the elbow.
- Trial name
- NCT06674434
- Testing
- Mobilization with Movement, Sustained Stretch
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Rheumatoid Arthritis
Relationship Between Grip Endurance, Disability of Upper Extremity and Quality of Life in Patients With RA
The aim of this study is to investigate the relationship between grip endurance, disability of upper extremity and quality of life in patients with rheumatoid arthritis.
- Trial name
- NCT04563455
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people
- Sponsor
- Izmir Katip Celebi University
Neuromuscular Disease, Neuromuscular Disability
The Effects of a Dynamic Arm Support in Daily Life
The goal of this mixed method study is to learn about how a dynamic arm support device (DAS) helps people with everyday activities. The study focuses on people with neuro(-muscular) conditions, age 16 and older.
- Conditions
- Neuromuscular Disease, Neuromuscular Disability, Assistive Technology, Activities of Daily Living
- Trial name
- NCT07121075
- Testing
- Dynamic arm support
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Hasselt University
Spinal Cord Injury, Cerebral Palsy
Experimental Evaluation of Wheelchair-Mounted Robotic Arms
Researchers from the University of South Florida's Rehabilitation Engineering program are looking for volunteers to participate in a research study for experimental evaluation of wheelchair-mounted robotic arms (WMRAs).
- Conditions
- Spinal Cord Injury, Cerebral Palsy, Multiple Sclerosis
- Trial name
- HRI (NCT01652352)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Hunter Syndrome
Study of Intrathecal Idursulfase-IT Administered in Conjunction With Elaprase® in Pediatric Patients With Hunter Syndrome and Early Cognitive Impairment
Study HGT-HIT-094 is a multicenter study designed to determine the effect on clinical parameters of neurodevelopmental status of monthly IT administration of idursulfase-IT 10 mg for 12 months in pediatric patients with Hunter…
- Trial name
- AIM-IT (NCT02055118)
- Testing
- idursulfase-IT, No IT treatment
- Where
- 9 sites in United States, Australia and 5 more
- Volunteers
- 58 people
- Sponsor
- Shire