Clinical trials: Upper Limb Surgery
Gastric Cancer, Microsatellite Instability
TremelImumab aNd Durvalumab For the Non-operatIve Management (NOM) of MSI-high Resectable GC/GEJC.
INFINITY is a Phase II, multicentre, single-arm, multi-cohort trial aimed at evaluating the activity and safety of the combination of tremelimumab and durvalumab as neoadjuvant (Cohort 1) and definitive (Cohort 2) treatment for…
- Trial name
- INFINITY (NCT04817826)
- Testing
- Durvalumab, Tremelimumab
- Where
- Italy
- Volunteers
- 31 people
- Sponsor
- Gruppo Oncologico del Nord-Ovest
Non-small Cell Lung Cancer
Combining Furmonertinib With Local Therapy for Inoperable Early-stage Lung Cancer: A Phase II Trial
The goal of this Single-arm, Phase II clinical trial is to learn whether ablation or stereotactic radiotherapy combined with furmonertinib can treat early-stage non-small cell lung cancer in patients who are inoperable or refuse…
- Trial name
- NCT07517640
- Testing
- furmonertinib, ablation, stereotactic body radiotherapy
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
Surgical Bleeding
Safety and Efficacy of WoundClot Surgical
The goal of this clinical trial is to verify that WoundClot Surgical helps stop bleedings which may occur during surgery. It will also help learn more about the safety of WoundClot Surgical.
- Trial name
- WCS-1 (NCT06696092)
- Testing
- Hemostatic Agent
- Where
- 8 sites in Romania
- Volunteers
- 72 people
- Sponsor
- Core Scientific Creations Ltd.
End Stage Renal Failure on Dialysis, Hyperplasia
Safety Study of the Vascular Wrap Paclitaxel-Eluting Mesh for Hemodialysis Vascular Access
The purpose of this study is to determine whether the long term use of the experimental Vascular Wrap(TM) Paclitaxel-Eluting Mesh is safe in the treatment of subjects needing hemodialysis access (via an expanded…
- Trial name
- NCT01033357
- Testing
- Graft, Vascular Wrap, Lifespan® ePTFE Vascular Graft Only
- Where
- 30 sites in United States
- Volunteers
- 222 people
- Sponsor
- Angiotech Pharmaceuticals
Fracture of Shaft of Humerus, Humerus Fracture
Surgical Interventions for the Treatment of Humeral Shaft Fractures
This study intends to determine the best surgical treatment for humeral shaft fractures. One third of the patients will be treated with open reduction and internal fixation with plate; one third, with bridge plate technique and…
- Trial name
- NCT02418260
- Testing
- Bridge Plate osteosynthesis, Locked intramedullary nail osteosynthesis, Open reduction and plate osteosynthesis
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Federal University of São Paulo
Robotic Gastrectomy, Stomach Neoplasms
Carina™ Surgical Platform for Minimal Radical Gastrectomy
To evaluate the safety and effectiveness of the laparoscopic surgical system（Carina™ Surgical Platform, developed by Ronovo Surgical, Inc) for use in gastrectomy.
- Trial name
- NCT07113340
- Testing
- Carina™ Surgical Platform, developed by Ronovo Surgical, Inc
- Where
- China
- Volunteers
- 20 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Intraocular Pressure, Spinal Anesthesia
Upper Extremity Position and Intraocular Pressure During Spinal Anesthesia: A Randomized Controlled Trial
This prospective randomized controlled trial evaluated the effect of two upper extremity positions on intraocular pressure (IOP) in adult patients undergoing surgery under spinal anesthesia.
- Conditions
- Intraocular Pressure, Spinal Anesthesia, Surgical Positioning
- Trial name
- UEP-IOP (NCT07424417)
- Testing
- Upper Extremity Positioning
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
Sarcopenia, Nerve Block
Regional Nerve Block for Upper Extremity Surgery in Patients With Sarcopenia
The goal of this observational study is to learn about the impact of sarcopenia (muscle loss) on the efficacy of regional nerve blocks and postoperative recovery in patients undergoing upper extremity surgery.
- Trial name
- NCT07757984
- Testing
- sarcopenia, Non-sarcopenia, General Anesthesia
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- Chang Gung Memorial Hospital
Surgery, Upper Extremity
Pain Control With Ketorolac and Nerve Block After Wrist and Hand Surgery
The purpose of this study is to learn about the effectiveness of different pain control options after hand and wrist surgery, specifically Ketorolac, Tylenol, and a regional nerve block.
- Trial name
- NCT07773155
- Testing
- Toradol, Oxycodone
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Chicago
Analgesia, Acute Pain
Pharmacokinetic Analysis of Bupivacaine in the Presence and Absence of Perineural Dexamethasone in Axillary Blockade
The investigators will conduct a prospective, randomized, double-blinded study using an axillary brachial plexus block in patients undergoing elective surgery of the distal forearm and hand to characterize and describe the…
- Conditions
- Analgesia, Acute Pain, Upper Extremity Injury
- Trial name
- NCT05359731
- Testing
- Bupivacaine Hydrochloride, Bupivacaine Hydrochloride with Dexamethasone
- Where
- Chile
- Volunteers
- 20 people
- Sponsor
- University of Chile
Proximal Humeral Fractures, Poor Bone Quality
Influence of Local Bone Status on Complications After Surgical Treatment of Proximal Humerus Fractures
The purpose of this study is to evaluate if poor bone quality increases the risk of specific types of treatment complications in patients with proximal humerus fractures treated with open reduction and angle-stable plates…
- Conditions
- Proximal Humeral Fractures, Poor Bone Quality, Treatment Complications
- Trial name
- NCT01143675
- Where
- 10 sites in Austria, China and 2 more
- Volunteers
- 148 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Anesthesia, Upper Extremity Injury
Clinical Evaluation of the Ultrasound-Guided Retroclavicular Brachial Plexus Block
The primary objective of this prospective, descriptive study is to evaluate the success rate of the retroclavicular brachial plexus block and catheter placement in 60 adult patients undergoing hand, wrist, or forearm surgery.
- Trial name
- NCT01605929
- Testing
- Retroclavicular Brachial Plexus Block and Catheter Insertion
- Where
- United States
- Sponsor
- Brigham and Women's Hospital
Transfemoral Amputees
Thigh Reduction Surgery of Above Knee Amputee Residual Limbs to Improve Prosthesis Fit and Patient Outcomes
The purpose of our study is to improve the fit and function of prosthetic sockets for above the knee amputees through the use of an outpatient thigh reduction surgical procedure.
- Trial name
- NCT02346019
- Testing
- Medial thighplasty with or without thigh liposuction
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Shirley Ryan AbilityLab
Fracture, Radius
Management of Pediatric Distal Radius Fractures : Conservative Treatment Versus Surgical Reduction
To compare functional and radiological assessment between two groups of children with displaced distal radius fractures : those who will receive surgical reduction and those who will not.
- Trial name
- NCT06459557
- Testing
- cast, surgical reduction
- Volunteers
- 52 people
- Sponsor
- Assiut University
Sleep Quality, Pain
Comparing the Efficacy of Earplugs and Eye Masks on Pain and Sleep Quality
Objective: To determine the superiority of earplugs and eye masks to each other and their efficacy in pain and sleep quality. Methods: The study was a three-arm randomised controlled trial.
- Conditions
- Sleep Quality, Pain, Intensive Care Medicine, Cardiac Surgery
- Trial name
- NCT07100002
- Testing
- Control Group, Earplug Group, Eye mask Group
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Giresun University
Breast Neoplasms
Impact of Robotic Versus Endoscopic Surgery on Nipple Nerve Function Following Nipple-Sparing Mastectomy for Breast Cancer
This is a multicenter, prospective, randomized parallel controlled two arm clinical trial, designed to systematically evaluate impact of robotic versus endoscopic surgery on breast nerve function in patients undergoing nipple…
- Trial name
- NCT07850154
- Testing
- Robotic-assisted nipple-sparing mastectomy, Endoscopic-assisted nipple-sparing mastectomy
- Where
- China
- Volunteers
- 374 people
- Sponsor
- Guangzhou Women and Children's Medical Center
Ischemic Stroke, Chronic Stroke
Investigation of Neural Stem Cells in Ischemic Stroke
A study of stereotactic, intracerebral injection of CTX0E03 neural stem cells into patients with moderate to moderately severe disability as a result of an ischemic stroke.
- Conditions
- Ischemic Stroke, Chronic Stroke, Hemiparesis, Arm Paralysis
- Trial name
- PISCES III (NCT03629275)
- Testing
- CTX0E03 Drug Product and delivery device
- Where
- 23 sites in United States
- Volunteers
- 15 people
- Sponsor
- ReNeuron Limited
Upper Extremity Surgery, Regional Anesthesia
Brachial Plexus Block vs General Anesthesia in Upper Extremity Surgery
This study compares two different anesthesia methods for upper arm and hand surgery: regional anesthesia (brachial plexus block) versus general anesthesia.
- Conditions
- Upper Extremity Surgery, Regional Anesthesia, General Anesthetic
- Trial name
- NCT07352839
- Testing
- Brachial Plexus Block, General Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Adana City Training and Research Hospital
Lymphedema, Lymphedema Arm
Lymphovenous Anastomosis for Breast Cancer Lymphedema
This multi-center cohort study focuses on evaluating the efficacy of lymphovenous anastomosis (LVA) for treating pitting lymphedema in female breast cancer survivors.
- Conditions
- Lymphedema, Lymphedema Arm, Breast Cancer Lymphedema, Lymphedema, Secondary
- Trial name
- NCT06302361
- Testing
- Lymphovenous anastomosis (LVA)
- Where
- Denmark
- Volunteers
- 47 people
- Sponsor
- Odense University Hospital
Rotator Cuff Tear
Prospective Study for Safety and Efficacy of InSpace™ in Rotator Cuff Tear Subjects
Title: One-arm, international, multi-center with competitive recruitment, prospective study to assess the safety and efficacy of OrthoSpace's InSpace™ in rotator cuff tear subjects scheduled for surgery of the rotator cuff - A…
- Trial name
- NCT00916994
- Testing
- SpaceGuard Balloon
- Where
- Israel
- Volunteers
- 58 people
- Sponsor
- OrthoSpace Ltd.