Clinical trials: Urinary Frequency/Urgency
Flank Pain, Urinary Bladder, Overactive
Therapeutic Merit of Solifenacin in the Mitigation of Ureteral Stent-induced Pain and Lower Urinary Tract Symptoms
Most ureteral stent insertions follow ureteroscopy procedures for stone management. Stents are essentially designed to prevent the blockage of the ureter.
- Trial name
- NCT01381120
- Testing
- Solifenacin succinate treatment, Oxycodone and acetaminophen combination treatment
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- Barrie Urology Associates
Urinary Urgency Incontinence
Post-Approval Study of the Neuspera Sacral Neuromodulation System
Prospective, multi-center, single-arm, post-approval study is designed to assess the long-term safety and efficacy data of the Neuspera Sacral Neuromodulation (SNM) System following commercial approval of the Neuspera SNM System.
- Trial name
- NSM-005 (NCT07144813)
- Testing
- Neuspera Implantable Sacral Neuromodulation System
- Where
- 20 sites in United States
- Volunteers
- 116 people
- Sponsor
- Neuspera Medical, Inc.
Lower Urinary Tract Symptoms, Healthy
Electronic Urinary Flowmeter to Improve Accuracy of Bladder Diaries .
The goal of this clinical trial is to give an answer to the question of whether an automated calculation of voided volumes would produce a more accurate set of bladder diary data when compared to the traditional ''eye-balling''…
- Conditions
- Lower Urinary Tract Symptoms, Healthy, Overactive Bladder (OAB)
- Trial name
- e-BLaDR (NCT05702294)
- Testing
- Diary pod ( measuring vessel that automatically calculates voided volume)
- Where
- United Kingdom
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Birmingham Women's and Children's NHS Foundation Trust
Overactive Bladder
Procedural Discomfort Related to Number of Intradetrusor Botox Injections
Injection of intradetrusor OnabotulinumtoxinA (BTX-A) is a highly efficacious therapy with a reliable safety profile and demonstrable improvements in subjective and objective measures for overactive bladder (OAB) symptom control.
- Trial name
- BIND (NCT05652036)
- Testing
- Intradetrusor Botox Injections
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- The Methodist Hospital Research Institute
Urinary Bladder, Overactive
Study to Assess the Efficacy and Safety of the Beta-3 Agonist Mirabegron (YM178) in Patients With Symptoms of Overactive Bladder
The study is intended to test efficacy, safety and tolerability of two doses of Mirabegron against placebo and compare the efficacy and safety with active comparator in patients with symptoms of overactive bladder.
- Trial name
- SCORPIO (NCT00689104)
- Testing
- Mirabegron, Tolterodine
- Where
- 218 sites in Australia, Austria and 28 more
- Volunteers
- 2,336 people
- Sponsor
- Astellas Pharma Inc
Overactive Bladder, Urge Urinary Incontinence
Pelvic Floor Muscle Training With Leva System for Urge Incontinence
This is a pilot non-comparative study to assess the effectiveness of pelvic floor muscle training guided by the leva® system for improving change in subject-reported incontinence-related quality of life and urgency urinary…
- Conditions
- Overactive Bladder, Urge Urinary Incontinence, Mixed Urinary Incontinence
- Trial name
- NCT03923348
- Testing
- Leva device
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- The Christ Hospital
Urinary Bladder, Overactive
Evaluating the Change of Overactive Bladder Symptoms in Women Post Pubovaginal Sling Procedure for Stress Incontinence
Pubovaginal sling (PVS) procedures are designed to curtail bladder leakage brought about by strenuous events such as child birth.
- Trial name
- NCT01194999
- Testing
- Pubovaginal sling procedure
- Where
- Canada
- Volunteers
- 132 people
- Sponsor
- Barrie Urology Associates
Urinary Frequency/Urgency
Development of Novel Cystometrics for Overactive Bladder
Urinary urgency is the key symptom of overactive bladder (OAB). A critical barrier in understanding OAB is the lack of a method to separate urgency that derives directly from bladder filling or what we term "tension sensor…
- Trial name
- NCT02060214
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Urologic Diseases, Urinary Bladder Diseases
A Study to Evaluate the Efficacy, Safety and Tolerability of Mirabegron and Solifenacin Succinate Alone and in Combination for the Treatment of Overactive Bladder
The purpose of this study is to examine how well two medicines in combination (solifenacin succinate and mirabegron) work in the treatment of bladder problems over a 12-week period.
- Conditions
- Urologic Diseases, Urinary Bladder Diseases, Urological Manifestations, Signs and Symptoms
- Trial name
- Symphony (NCT01340027)
- Testing
- Mirabegron, Solifenacin succinate
- Where
- 133 sites in Belarus, Belgium and 18 more
- Volunteers
- 1,307 people
- Sponsor
- Astellas Pharma Europe B.V.
Overactive Bladder
A Study Of Efficacy And Safety Of Fesoterodine In Vulnerable Elderly Subjects With Overactive Bladder
This study is designed to assess the efficacy and safety of a flexible dose regimen of fesoterodine on urgency urinary incontinence (UUI) episodes in vulnerable elderly subjects with overactive bladder (OAB).
- Trial name
- NCT00928070
- Testing
- Fesoterodine
- Where
- 125 sites in United States
- Volunteers
- 566 people
- Sponsor
- Pfizer
Lower Urinary Tract Symptoms, Overactive Bladder Syndrome
Testing MitoQ on Lower Urinary Tract Symptoms in Older Women With Metabolic Syndrome
The goal of this clinical trial is to test the effect of a supplement called MitoQ (mitoquinol mesylate) on bladder symptoms such as urgency and frequency in women 50 years and older who have the metabolic syndrome.
- Trial name
- Mito-LUTS (NCT06351683)
- Testing
- MitoQ (mitoquinol mesylate)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Iman Al-Naggar, PhD
Urgency Urinary Incontinence
Sacral Neuromodulation and the Microbiome
Sacral neuromodulation (SNM) which is approved as a treatment for men and women with urgency urinary incontinence (UUI), urgency frequency syndrome, urinary retention and anal incontinence, is a procedure designed to deliver…
- Trial name
- NCT02833402
- Testing
- InterStim Therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Northwestern University
Overactive Bladder Syndrome, Overactive Bladder
BTL Emsella Chair Versus Sham for the Treatment of Overactive Bladder
The purpose of this clinical trial is to compare the Emsella Chair therapy to Sham and to determine whether electromagnetic technology is effective in the treatment of overactive bladder (OAB).
- Conditions
- Overactive Bladder Syndrome, Overactive Bladder, Urinary Frequency, Urinary Urgency
- Trial name
- EmsellaOAB (NCT04873037)
- Testing
- BTL Emsella Chair
- Where
- United States
- Volunteers
- 166 people
- Sponsor
- Corewell Health East
Overactive Bladder, Urge Incontinence
Repetitive Transcranial Magnetic Stimulation in Women With Overactive Bladder With Urgency Incontinence
Overactive bladder (OAB) affects an estimated 16-30% of women in the US and urgency urinary incontinence (UUI) affects 7-11% of women with OAB.
- Trial name
- NCT05099419
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Southern California
Overactive Bladder
Clinical Study to Evaluate the Treatment Effect and Safety of BAY1817080 in Patients With Overactive Bladder (OAB)
The aim of the study is to determine how well the drug BAY1817080 works in OAB patients with urgency urinary incontinence (UUI), defined as involuntary leakage of urine, accompanied or immediately preceded by a sudden compelling…
- Trial name
- OVADER (NCT04545580)
- Testing
- BAY1817080
- Where
- 28 sites in Australia, Austria and 7 more
- Volunteers
- 99 people
- Sponsor
- Bayer
Urge Incontinence, Urgency-frequency Syndrome
The Effect of Solifenacin Used for Lower Urinary Tract Symptoms on Sexual Function
This study aims to determine whether Solifenacine used for lower urinary tract symptoms improves sexual function and if so does this improvement differs between premenopausal and postmenopausal women.
- Trial name
- NCT05391425
- Testing
- no intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Istanbul University
Overactive Bladder
Efficacy and Safety Study of Botulinum Toxin Type-A (Dysport®) in Continent Female Subjects Suffering From Idiopathic Overactive Bladder
The purpose of this study is to determine the optimal dose of botulinum toxin type A injected in the detrusor muscle to improve urinary symptoms, urodynamic parameters and quality of life of continent women suffering from…
- Trial name
- NCT00578097
- Testing
- Botulinum toxin type A
- Where
- 34 sites in Belgium, Czechia and 6 more
- Volunteers
- 81 people
- Sponsor
- Ipsen
Urinary Incontinence
Effect and Safety Of Detrol LA In Men With Overactive Bladder Symptoms With Or Without Bladder Outlet Obstruction
The primary objective of the trial is to evaluate the effect of tolterodine ER plus tamsulosin versus placebo on patient perception of overall treatment benefit in men who have frequency and urgency, with or without urinary urge…
- Trial name
- NCT00147654
- Testing
- Tolterodine ER 4 mg QD, Tamsulosin 0.4 mg QD
- Where
- 95 sites in United States
- Volunteers
- 830 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Urinary Bladder, Overactive, Overactive Bladder
Solifenacin Flexible Dosing Study in Frequent Micturition Patients With and Without Urgency
The purpose of the study is to compare the effect of solifenacin succinate between frequent micturition patients with urgency and those without urgency.
- Trial name
- NCT00979472
- Testing
- Solifenacin
- Where
- 9 sites in South Korea
- Volunteers
- 291 people
- Sponsor
- Asan Medical Center
Constipation
Randomized, Double-Blinded, Placebo-Controlled Trial of Laxatives for Children With Urge Syndrome
HYPOTHESIS: Is MiraLAX an effective treatment of pediatric urinary urge syndrome? OBJECTIVE: Polyethylene glycol (PEG) is common first-line therapy for urinary symptoms despite minimal evidence-based support.
- Trial name
- NCT00765557
- Testing
- MiraLAX
- Volunteers
- 138 people
- Sponsor
- University of Texas Southwestern Medical Center