Clinical trials: Urinary System Disorder
Healthy, Chronic Kidney Diseases
A Study of Renal Microvessel Imaging for Chronic Kidney Disease
The purpose of this research is to study the efficacy of ultrasound microvessel imaging for evaluation of Chronic Kidney Disease.
- Trial name
- NCT05764642
- Testing
- Definity, Super-resolution ultrasound imaging
- Where
- 2 sites in United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Nonfunctioning Kidney, Renal Cell Carcinoma (RCC)
Laparoscopic Versus Open Nephrectomy : Clinical Effectivness and Cost Analysis
To evaluate and compare clinical effectiveness (operative time, blood loss, hospital stay, complications and etc) and cost analysis' between laparoscopic nephrectomy and open nephrectomy .
- Trial name
- NCT07461090
- Testing
- open or laparoscopic nephrectomy
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Urinary Retention
Normal and Pathological Values of Postvoiding Residual Volume in Early Postpartum Period and Their Predisposing Factors
Aim of this study is to asses post voiding residual volume by ultrasound scan 3th day after delivery with consecutive scan after 6 weeks, and determination of data dispersion among the population of primiparas.
- Trial name
- PAREZ (NCT03958279)
- Testing
- Ultrasound measurement of residual volume in the urinary bladder, Questionnaire
- Where
- Slovakia
- Volunteers
- 930 people, healthy volunteers welcome
- Sponsor
- Comenius University
Sexual Dysfunction, Stress Incontinence
A Study to Measure the Degree and Effectiveness of the Various vSculpt Operating Modes
A pilot study to determine the degree and effectiveness of the various modes of vSculpt, an over-the-counter "OTC" medical device, on enhanced genital blood flow and improvement in quality of life in menopausal women who suffer…
- Trial name
- NCT02856490
- Testing
- vSculpt, InTone
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Joylux, Inc.
Type 2 Diabetes Mellitus, Diabetes Mellitus, Type 2
A Comparison Of Study Drug Blood Levels After One Dose Of GSK189075 In Subjects With Normal And Reduced Kidney Function
This is an open-label study that will measure blood levels of different parts of a drug called GKS189075. People participating in this study will receive a single dose of 250mg GSK189075 by mouth.
- Conditions
- Type 2 Diabetes Mellitus, Diabetes Mellitus, Type 2, Renal Insufficiency
- Trial name
- NCT00501462
- Testing
- GSK189075
- Where
- 4 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Cardiovascular Diseases, Hypertension
Uppsala Self-Screening of Cardiovascular Health
U-SCREEN is a randomized controlled trial evaluating whether systematic home-based multimodal screening for cardiovascular risk conditions, offered to residents in Region Uppsala turning 50, 55, 60, 65, 70 or 75 years of age, can…
- Conditions
- Cardiovascular Diseases, Hypertension, Dyslipidemias, Diabetes Mellitus
- Trial name
- U-SCREEN (NCT07614659)
- Testing
- Home-based multimodal cardiovascular screening
- Where
- Sweden
- Volunteers
- 45,000 people, healthy volunteers welcome
- Sponsor
- Johan Sundström
Urinary Incontinence
Assessment of Two Postoperative Techniques Used to Predict Voiding Efficiency After Gynecologic Surgery
After gynecologic surgery, it may be difficult to void (urinate). This problem is usually short-term with normal function returning within a few days to a few weeks.
- Trial name
- NCT00392210
- Testing
- Voiding Trial
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Haemodialysis Complication, Major Adverse Cardiac Events
Novel Cardiovascular Biomarkers in Patients With Kidney Disease
Chronic kidney disease (CKD) is a long-term condition where the kidneys do not work as well as they should. End-stage kidney failure (ESKD) is the final, irreparable stage of chronic kidney disease (CKD), where kidney function…
- Trial name
- CBKD (NCT06037759)
- Testing
- Cardiac Biomarkers, Lipidomics, Proteomics
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Urinary Incontinence
Comparison of Surgical Procedures to Reduce Urinary Stress Incontinence
The primary aim of this clinical trial is to compare the treatment success for two surgical procedures that are frequently used and have similar cure rates, yet have not been compared directly to each other in a large, rigorously…
- Trial name
- SISTEr (NCT00064662)
- Testing
- Burch Modified Tanagho, Autologous Fascia Sling
- Where
- 9 sites in United States
- Volunteers
- 655 people, healthy volunteers welcome
- Sponsor
- Carelon Research
Placebo Analgesia
Oxytocin and Arginine Vasopressin in Pain Relief
Background: Oxytocin, a substance produced mostly in the brain, plays a role in influencing social interactions and reactions to stress, and may be related to pain.
- Trial name
- NCT01328561
- Where
- United States
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Overactive Bladder
Evaluation of the Effect of Dried Cranberry Powder in Women With Dry OAB
A randomized, double-blind, placebo controlled study to evaluate the efficacy of dried cranberry at 500 mg daily in women with overactive bladder for 6-months.
- Trial name
- NCT03017170
- Testing
- Dried Cranberry
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Mild Moderate, or Severe Renal Impairment
An Open-label, Parallel-group Study to Determine the Pharmacokinetics of a Single Dose of AFQ056 in Subjects With Renal Impairment Compared to Healthy Subjects
The aim of this study was to characterize the pharmacokinetics and safety of AFQ056 in subjects with a different degree of renal impairment.
- Trial name
- NCT01442259
- Testing
- AFQ056
- Where
- Germany
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals
Other Acute Illnesses Presenting to the Hospital, Heart Failure
Evaluation of Implementation of a National Point-of-Care Ultrasound Training Program
This VA QUERI Partnered Evaluation Initiative will evaluate the impact of an immersive Point-of-care Ultrasound (POCUS) Training Course on provider skill acquisition and retention; the frequency of POCUS use by trained providers…
- Conditions
- Other Acute Illnesses Presenting to the Hospital, Heart Failure, Pneumonia, Deep Venous Thrombosis
- Trial name
- NCT03296280
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
AVP Deficiency, Diabetes Insipidus
Plasma Oxytocin Response to Oral Estrogens in Healthy Controls and AVP-Deficiency
The PHOENIX study aims to investigate whether oral estradiol valerate (EV) and ethinylestradiol (EE) can stimulate oxytocin (OXT) and neurophysin-1 (NP-1) release in humans.
- Trial name
- PHOENIX (NCT07361263)
- Testing
- estradiol valerate, esthinylestradiol
- Where
- Switzerland
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Urinary Retention, Pelvic Organ Prolapse
Urinary Catheter Self-Discontinuation After Urogynecology Surgery
The goal of this randomized clinical trial is to determine if removal of transurethral urinary catheters by patients at home is as safe as catheter removal in the office following urogynecologic surgery.
- Conditions
- Urinary Retention, Pelvic Organ Prolapse, Stress Urinary Incontinence, Catheter Related Complication
- Trial name
- CATH (NCT05860634)
- Testing
- Catheter self-discontinuation
- Where
- 4 sites in United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Chronic Kidney Disease
Study to Collect Samples for MIST Analysis of Zibotentan and Bioavailability of Zibotentan and Dapagliflozin in Heatlhy Participants
The study will have 2 independent parts: Part 1 of the study is intended to collect samples for Metabolites in Safety Testing (MIST) analysis after administration of multiple doses of zibotentan.
- Trial name
- NCT04991571
- Testing
- Zibotentan (Treatment A), Dapagliflozin (Treatment A), Zibotentan/Dapagliflozin - Formulation 1 (Treatment B)
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Chronic Renal Failure
Clinical Study to Compare the Pharmacokinetics and Safety of D113 With CKD-349 in Healthy Volunteers
This study is a randomized, open-label, single dosing, 3-treatment, 6-sequence, 3-period, crossover-design study to compare the pharmacokinetics and safety of D113 with CKD-349 in healthy volunteers.
- Trial name
- NCT04952506
- Testing
- CKD-349 F1 Tab., CKD-349 F2 Tab., D113 Tab.
- Where
- South Korea
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Acute Kidney Injury, Acute Heart Failure
Predictors of Acute Kidney Injury in Patients With Acute Decompensated Heart Failure in Emergency
Acute Decompensated Heart Failure ADHF is one of the leading causes of hospitalization. ADHF is a growing global health problem affecting more than 26 million individuals worldwide Acute Kidney Injury AKI is a common event in the…
- Trial name
- NCT06463964
- Testing
- Serum Creatinine
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Urinary Incontinence
Evaluation Trial of Handheld Urinal for Adult Use
Usability and efficacy evaluation of a prototype handheld urinal for adult use
- Trial name
- NCT04897932
- Testing
- RS - WP06
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Binding Sciences Limited
Insulin Pump Therapy in Treating Diabetic Nephropathy
Effect Insulin Pump Therapy to Patients With Diabetic Nephropathy
The recent study suggested that oxidative stress resulting from increased production of reactive oxygen species (ROS) plays a crucial role in the development of diabetic complications.
- Trial name
- NCT03174821
- Testing
- Insulin pump
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
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