Clinical trials: Urinary Tract Infection(UTI)
Urinary Tract Infections
Symptomatic Therapy of Uncomplicated Lower Urinary Tract Infections in the Ambulatory Setting.
We propose to perform a randomized controlled patient and assessor blind trial in women between the ages of 18 to 70 years with acute uncomplicated UTI to evaluate initial symptomatic treatment for 3 days with the non-steroidal…
- Trial name
- NCT01039545
- Testing
- Diclofenac, Norfloxacin
- Where
- Switzerland
- Volunteers
- 253 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Urinary Tract Infections
Nutraceutical Efficacy for rUTI
This is a study designed to evaluate the efficacy of a nutraceutical as a non-antibiotic treatment to prevent recurrent urinary tract infections in women that have completed menopause and are on vaginal estrogen therapy.
- Trial name
- NCT03395288
- Testing
- D-Mannose
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Washington University School of Medicine
Urinary Tract Infections
Evaluation of Urine Samples and Their Relation to Urinary Tract Infection
The aim is to explore the human urine composition and its relation to urine tract infections
- Trial name
- NCT03522766
- Testing
- urine sample
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Coloplast A/S
Urinary Tract Infection During Pregnancy
Developing Self-care Behaviors for Urinary Tract Infections
The research was designed in a randomized controlled quasi-experimental type in order to reveal the effect of "Self-Care Behaviors Development Program for Urinary Tract Infections" prepared according to Orem's Self Care Model on…
- Trial name
- NCT04832581
- Testing
- The Self-Care Behavior Development Program
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Urinary Tract Infections
An Open-label Trial to Evaluate the Safety of an Essential Oil Infused Perineal Towel
The purpose of this study is to assess the safety (absence of skin irritation) of a feminine hygiene product for perineal hygiene prior to undertaking a clinical effectiveness trial.
- Trial name
- WIPEAWAY (NCT02509403)
- Testing
- Essential oils infused Perineal Hygiene wipe
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alberta
Pneumonia, Bacterial, Pneumonia Childhood
Discharge Stewardship in Children's Hospitals
The goal of this interventional study is to test if a discharge stewardship bundle is effective at reducing inappropriate antibiotic prescriptions at hospital discharge for children with the three common infections…
- Conditions
- Pneumonia, Bacterial, Pneumonia Childhood, Urinary Tract Infections, Soft Tissue Infections
- Trial name
- DISCO (NCT05826873)
- Testing
- Discharge antibiotic stewardship intervention
- Where
- 5 sites in United States
- Volunteers
- 1,131 people
- Sponsor
- Children's Hospital of Philadelphia
Urinary Tract Infections
General Practitioner Reassessment of Urinary Infection Antibiotherapy Prescribed by Emergency Departments
Urinary infections are at the origin of many emergency department consultations and antibiotic prescriptions. Increase of bacteria resistance to antibiotics is promoted by an inappropriate use of those antibiotics but initial…
- Trial name
- ATB-IU (NCT03928951)
- Testing
- General practitioner reassessment of urinary infection antibiotherapy prescribed by emergency departments
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Urinary Tract Infections
Impact of Sterilization Technique on Incidence of Urinary Tract Infection After Cystoscopy
The purpose of this study is to verify that the incidence rate of urinary tract infections after a routine outpatient cystoscopy is the same for non-sterile (clean) and sterile procedural techniques.
- Trial name
- NCT00177112
- Testing
- clean patient preparation for cystoscopy, sterile patient preparation for cystoscopy
- Where
- United States
- Volunteers
- 275 people
- Sponsor
- University of Minnesota
Urinary Tract Infection
Nettle and Cranberry Capsules for Prevention of Urinary Tract Infection
This study investigates whether the oral intake of a nettle and cranberry complex capsule may prevent recurrent urinary tract infection (rUTI).
- Trial name
- NCT05880602
- Testing
- Nettle and Cranberry complex capsules
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chung Shan Medical University
COVID-19 Infection, Genitourinary Cancer
Impact of COVID-19 on GU Disease
The purpose of this research study is to identify patients with GU disease with active or past COVID-19 infection. Participants will be asked to: Complete an Online COVID-19 Questionnaire.
- Conditions
- COVID-19 Infection, Genitourinary Cancer, Benign Urologic Conditions
- Trial name
- NCT04761107
- Where
- United States
- Volunteers
- 15,240 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Surgical Complication, Colonic Disease
Immediate Versus Early (24-hours) Urinary Catheter Removal After Elective Minimally Invasive Colonic Resection
The primary aim of this study is to compare the rate of acute urinary retention (AUR) after immediate compared to early (24-hours) removal of urinary catheter (UC) in patients undergoing minimally invasive colorectal resection.
- Conditions
- Surgical Complication, Colonic Disease, Postoperative Complications, Urinary Retention Postoperative
- Trial name
- NCT05249192
- Testing
- Immediate urinary catheter removal, Early urinary catheter removal
- Where
- Italy
- Volunteers
- 216 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Urinary Tract Infection (Diagnosis)
Extending Urine Analysis By Direct Mass Spectrometry
The aim of this study is to evaluate the effect of an extension of conventional urine diagnostics with mass spectrometry in patients with a suspected UTI.
- Trial name
- NCT02966977
- Testing
- Conventional microbiological identification by culture plate, Direct mass spectrometry identification from urine sample
- Where
- Switzerland
- Volunteers
- 192 people
- Sponsor
- University Hospital, Basel, Switzerland
Healthcare-associated Pneumonia (HCAP), Bloodstream Infections (BSI)
Study of Cefiderocol (S-649266) or Best Available Therapy for the Treatment of Severe Infections Caused by Carbapenem-resistant Gram-negative Pathogens
This study is designed to provide evidence of efficacy of cefiderocol in the treatment of serious infections in adult patients caused by carbapenem-resistant Gram-negative pathogens.
- Conditions
- Healthcare-associated Pneumonia (HCAP), Bloodstream Infections (BSI), Hospital Acquired Pneumonia (HAP), Complicated Urinary Tract Infection (cUTI)
- Trial name
- CREDIBLE - CR (NCT02714595)
- Testing
- Cefiderocol, Best Available Therapy
- Where
- 85 sites in United States, Brazil and 14 more
- Volunteers
- 152 people
- Sponsor
- Shionogi
Urinary Tract Infections, Cystitis
Oral Sulopenem Versus Amoxicillin/Clavulanate for Uncomplicated Urinary Tract Infection in Adult Women
Study 310 is a clinical study which compares the effectiveness of oral sulopenem versus oral amoxicillin/clavulanate for the treatment of adult women with uncomplicated urinary tract infection.
- Trial name
- REASSURE (NCT05584657)
- Testing
- Sulopenem etzadroxil/probenecid, Amoxicillin/clavulanate
- Where
- 167 sites in United States
- Volunteers
- 2,229 people
- Sponsor
- Iterum Therapeutics, International Limited
E.Coli Infections
Vaccine Against Escherichia Coli Infection
This Phase I multi-center placebo controlled study is conducted in healthy women with a history of recurrent urinary tract infections (UTI) aged between 18 and 70 years.
- Trial name
- NCT02289794
- Testing
- E.coli bioconjugate vaccine
- Where
- Switzerland
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- GlycoVaxyn AG
Urinary Tract Infection
Efficacy and Safety of Nitrofurantoin in the Treatment of Uncomplicated Urinary Tract Infections in Adults
The study aims to investigate bacteriological efficacy of a nitrofurantoin formulation given twice daily for seven days in the treatment of adult patients with microbiologically confirmed uncomplicated urinary tract infection.
- Trial name
- NCT01092351
- Testing
- Nitrofurantoin
- Where
- Mexico
- Volunteers
- 37 people
- Sponsor
- Mepha Ltd.
Infectious Disease
Temocillin in ESBL-Enterobacteriaceae Infections
Because of the increasing incidence of infections with multi-drug resistant enterobacteriaceae, we need alternative treatments to spare carbapenems.
- Trial name
- TMO2016 (NCT05413772)
- Testing
- Temocillin
- Where
- 2 sites in France
- Volunteers
- 29 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Recurrent Urinary Tract Infection
Periurethral vs Intravaginal Estrogen for Prevention of Recurrent Urinary Tract Infections
Due to rising antibiotic resistance, there has been a focus on non-antibiotic prophylactic measures for postmenopausal patients with recurrent urinary tract infections (rUTI), one of which is the safe and efficacious option of…
- Trial name
- TAPER (NCT05472779)
- Testing
- Periurethral application of estradiol cream, Intravaginal application of estradiol cream
- Where
- 4 sites in United States
- Volunteers
- 114 people
- Sponsor
- Stephanie Wang Zuo
Postoperative Urinary Tract Infection, Laparoscopic Hysterectomy
Effect of Vulvar Re-Antisepsis Before CO₂ Cystoscopy Performed After Laparoscopic Hysterectomy on Postoperative Urinary Infections
This prospective observational study aims to evaluate whether additional vulvar re-antisepsis before intraoperative cystoscopy reduces the incidence of postoperative urinary tract infections (UTIs) in patients undergoing total…
- Conditions
- Postoperative Urinary Tract Infection, Laparoscopic Hysterectomy, Cystoscopy, Antisepsis
- Trial name
- NCT07232446
- Testing
- Additional Vulvar Re-Antisepsis Before Cystoscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people
- Sponsor
- Alaattin Karabulut
Urinary Tract Infections
EXtended Use of FOsfomycin for the Treatment of CYstitis in Primary Care
Cystitis is the most frequent reason for women to visit their general practitioner. More than 600.000 women suffer from urinary tract infections in The Netherlands each year.
- Trial name
- EXFOCY (NCT05254808)
- Testing
- Fosfomycin, Nitrofurantoin
- Where
- 4 sites in Netherlands
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- MJM Bonten