Clinical trials: Urinary Tract Infection, Recurrent
Recurrent Urinary Tract Infection
The Effect of ASTARTE™ on Recurrent Urinary Tract Infection
Investigate the effect of dietary supplements/probiotic ASTARTE™ ( L. crispatus, L. rhamnosus, L. jensenii, L. gasseri) on the microbiome composition in the intestine and vagina and thereby a reduction of risk factors for the…
- Trial name
- rUTI (NCT05553652)
- Testing
- ASTARTE™ oral capsules
- Where
- Denmark
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Recurrent Uti
Intravesical Gentamicin to Prevent Recurrent UTI
Feasibility assessment of intravesical gentamicin instillation (putting antibiotics directly into the bladder) versus the current standard of care of oral nitrofurantoin prophylaxis (taking a low dose of antibiotics by mouth…
- Trial name
- NCT06332781
- Testing
- Gentamicin, Nitrofurantoin
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Urinary Tract Infections
A Study of Vaginal MicroFlora and Immune Profiles of Patients With Recurrent Urinary Tract Infection
The purpose of this study is to determine the extent to which vaginal microflora and immune profiles of patients with urinary tract infection (UTI) differ from healthy controls.
- Trial name
- NCT00216853
- Where
- Canada
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Recurrent Uti
A Novel Probiotic-antibiotic Combination to Prevent Recurrent Urinary Tract Infections
Patients with recurrent UTI were randomized to receive either the probiotic Sacchromyces Boulardii at enrollment, and the intracellularly active Ciprofloxacin with their first UTI episode after enrollment, or they received…
- Trial name
- NCT06149676
- Testing
- Saccharomyces Boulardii 250 MG [Florastor]
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Recurrent Urinary Tract Infections
Association Between Deficiency of MBL (Mannose-Binding Lectin) and Polymorphisms in MBL2 Gene to Urinary Tract Infection
Due to genetic polymorphism about 15%-30% of the world population have low levels of MBL (Mannose Binding Lectin) in serum (below 500ng/mL).
- Trial name
- NCT00678028
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Recurrent Urinary Tract Infection in Adult Women
Evaluating the Effect of the Probiotic on Recurrent Urinary Tract Infection in Adult Women
Urinary tract infections (UTIs) are the most common bacterial infections in women, with about 50% of women experiencing at least one UTI in their lifetime.
- Trial name
- NCT03366077
- Testing
- Probiotic
- Where
- Sweden
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- BioGaia AB
Recurrent Urinary Tract Infection
Recurrent Urinary Tract Infections and the Microbiome
The primary objective is to determine if polymerase chain reaction (PCR) (UTIP™) is more sensitive in identifying urinary tract infections (UTI's) than standard urine cultures.
- Trial name
- NCT04831840
- Where
- 2 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Miami
Recurrent Urinary Tract Infections in Women
Vaccine for Recurrent Urinary Tract Infections in Women
The purpose of this study is determine whether a vaginal mucosal vaccine given to women with a history of recurrent urinary tract infections can reduce the number of infections occurring in a six-month study period, as compared…
- Trial name
- NCT00261248
- Testing
- Immunization with inactivated bacteria
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Urinary Tract Infection
Effects of Cranberry-Containing Products in Women With Recurrent Urinary Tract Infections (UTIs)
The purpose of this study is to determine the role of cranberry-containing products in preventing urinary tract infections (UTIs).
- Trial name
- NCT00100061
- Testing
- Cranberry juice
- Where
- Canada
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Urinary Tract Infections
Identification of Predictive Blood Biomarkers of Recurrent Urinary Tract Infections
Urinary tract infections affect more than 130 million people worldwide each year. Almost 50% of women will have at least one urinary tract infection during their lifetime, usually cystitis.
- Trial name
- Predict-UTI (NCT03819712)
- Testing
- Collection of blood samples, Collection of fecal samples, Collection of urine samples
- Where
- France
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Recurrent Urinary Tract Infection, Hypoestrogenism
Adherence to Vaginal Estrogen Therapy in Hypoestrogenic Women With Recurrent Urinary Tract Infections
The goal of this clinical trial is to learn about medication adherence to difference types of vaginal estrogen in women with low levels of estrogen (for example, post-menopausal women) who have recurrent urinary tract infections.
- Trial name
- NCT06353269
- Testing
- Estring Vaginal Product, Vagifem, Estrace 0.01% Vaginal Cream
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Recurrent Urinary Tract Infection, Vaginal Atrophy
Prevention of Recurrent UTI Using Vaginal Testosterone Versus Placebo Placebo
Women over the age of 60 years have an estimated 10 to 15 % risk of recurrent urinary tract infections (UTI). This is believed to be due to hormonally induced changes in the vaginal flora associated with menopause.
- Conditions
- Recurrent Urinary Tract Infection, Vaginal Atrophy, Postmenopausal Disorder
- Trial name
- PIVoT (NCT04807894)
- Testing
- Vaginal Cream with Applicator
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Jefferson Drapkin
E.Coli Infections
Vaccine Against Escherichia Coli Infection
This Phase I multi-center placebo controlled study is conducted in healthy women with a history of recurrent urinary tract infections (UTI) aged between 18 and 70 years.
- Trial name
- NCT02289794
- Testing
- E.coli bioconjugate vaccine
- Where
- Switzerland
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- GlycoVaxyn AG
Urinary Tract Infections, Recurrent UTI
Probiotics and Multi-Drug Resistant Urinary Tract Infection
This pilot study is a single-site randomized, double blinded placebo-controlled in females with recurrent multi-drug resistant (MDR) urinary tract infections(UTI).
- Conditions
- Urinary Tract Infections, Recurrent UTI, Antibiotic Resistant Infection
- Trial name
- NCT03644966
- Testing
- Bifidobacterium infantis, Antibiotics
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Ochsner Health System
Atrophic Vaginitis, Menopause
Vaginal and Urinary Microbiome Trial
A randomized controlled trial looking at the effects of vaginal estrogen and a nonhormonal alternative on the vaginal and urinary microbiome in women with genitourinary syndrome of menopause.
- Conditions
- Atrophic Vaginitis, Menopause, Recurrent Urinary Tract Infections
- Trial name
- NCT02869165
- Testing
- Conjugated equine estrogen topical cream, Apricot kernel oil
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Urinary Tract Infections
Effect of Probiotics on Recurrent Urinary Tract Infections
Randomized clinical trial to evaluate the effect of a probiotic mixture of Lactobacillus plantarum on recurrent urinary tract infections in women.
- Trial name
- CYSCARE (NCT06192966)
- Testing
- Food supplement
- Where
- 4 sites in Spain
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- AB Biotics, SA
Recurrent Urinary Tract Infection
Faecal Microbiota Transplantation as Means of Preventing Recurrent Urinary Tract Infections
This study investigates Faecal microbiota transplantation (FMT) in prevention of recurrent urinary tract infections (UTIs) caused either by sensitive E. coli or ESBL-E. coli.
- Trial name
- FMT-UTI (NCT06050148)
- Testing
- Feacal microbial transplantation (FMT)
- Where
- Finland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Urinary Tract Infection
Cranberry for the Prevention of Urinary Tract Infections
This study aims to determine whether a cranberry concentrate reduces recurrent urinary tract infections (UTIs) in women. Approximately 150 adult women will be recruited to participate in this study.
- Trial name
- NCT02454309
- Testing
- Cranberry concentrate
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Urinary Tract Infection
Cranberry on Urinary Tract Infections
This study aims to determine whether a cranberry concentrate reduces recurrent urinary tract infections (UTIs) in women who consume it. About 150 adult women will participate in this study.
- Trial name
- NCT01881165
- Testing
- Cranberry
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of British Columbia
Urinary Tract Infection, Recurrent Urinary Tract Infection
Effects of Antibiotic Prophylaxis on Recurrent UTI in Children
Approximately, 3% of males and 8% of females will develop a urinary tract infection (UTI) during childhood, and most of these will be effectively treated by short-term antibiotic therapy.
- Trial name
- NCT02357758
- Testing
- Antibiotic Prophylaxis
- Where
- Canada
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's