Clinical trials: Urinary Tract Stones
Nephrolithiasis
Hydrochlorothiazide for Kidney Stone Recurrence Prevention
The investigators plan to assess the efficacy of standard and low dose HCTZ treatment in the recurrence prevention of calcium-containing kidney stones.
- Trial name
- NOSTONE (NCT03057431)
- Testing
- 12.5 mg hydrochlorothiazide, 25.0 mg hydrochlorothiazide, 50.0 mg hydrochlorothiazide
- Where
- 12 sites in Switzerland
- Volunteers
- 416 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Kidney Calculi
Ambulatory Versus Inpatient Percutaneous Nephrolithotomy
The goal of the study is to determine if ambulatory tubeless PCNL is safe and effective compared to inpatient PCNL with a nephrostomy tube.
- Trial name
- NCT04690010
- Testing
- Ambulatory tubeless PCNL, Inpatient PCNL with nephrostomy tube
- Where
- United States
- Sponsor
- University of California, San Francisco
Kidney Calculi
Are There Protective Effects of Antioxidants, Calcium Channel Blocker and Angiotensin Receptor Blocker Against Extracorporeal Shockwaves Lithotripsy Induced Renal Injury?
This study will be conducted to evaluate the protective effects and mechanisms of antioxidants (vitamins A, C, E and Selenium), calcium channel blocker (Verapamil) and angiotensin receptor blocker (Lozartan) against shock wave…
- Trial name
- SWL (NCT01675362)
- Testing
- Antioxidant group, Calcium Channel Blockers, Angiotensin receptor blocker group
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Mansoura University
Kidney Stones
Visceral Pain From the Upper Urinary Tract - a Trial on the Effect of Morphine and Oxycodone in Patients Undergoing PCNL
The purpose of this study is to investigate the effect of oxynorm versus morphine after operation for kidney stone (PCNL). In addition the relationship between pain symptoms and referred sensory and trophic changes will be…
- Trial name
- NCT00784472
- Testing
- oxycodone, morphine
- Where
- Denmark
- Volunteers
- 55 people
- Sponsor
- Katja venborg Pedersen
Kidney Stone
Trial of Efficacy of the RetroPerc Device
The purpose of this study is to determine the efficacy of RetroPerc® in obtaining renal access for percutaneous nephrolithotomy
- Trial name
- NCT05022537
- Testing
- retrograde nephrostomy, antegrade nephrostomy
- Where
- United States
- Sponsor
- The University of Texas Health Science Center, Houston
Kidney Calculi, Nephrolithiasis
Nebulized Glubran 2-Assisted Tubeless PCNL Versus Conventional PCNL
This prospective randomized controlled study will compare two techniques used after percutaneous nephrolithotomy, a procedure for removing kidney stones.
- Trial name
- NCT07749807
- Testing
- Nebulized Glubran 2-Assisted Tubeless PCNL, Conventional PCNL With Nephrostomy Tube
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Benha University
Renal Calculi
Comparison of Extracorporeal Shock Wave Lithotripsy (ESWL) and Ultra-mini Percutaneous Nephrolithotomy (PCNI), in Renal Stones <20 mm.
There is a dearth of information comparing ultra-mini PNCL with ESWI in Pakistan for kidney stones smaller than 20 mm. Hence the current study was planned with the objective of comparing the outcome of ESWL and ultra-mini PCNL in…
- Trial name
- NCT07610252
- Testing
- Ultra-mini PCNL, Extracorporeal shock wave lithotripsy
- Where
- Pakistan
- Volunteers
- 138 people
- Sponsor
- Muhammad Aamir Latif
Kidney Stone, Retrograde Intrarenal Surgery
Ureteral Stenting After Retrograde Intrarenal Surgery for Renal Stones
Several studies evaluated the benefit of a short-term external ureteral catheter (UC) compared to double-J (DJ) ureteral stent after flexible ureteroscopy (URS); the results were controversial.
- Conditions
- Kidney Stone, Retrograde Intrarenal Surgery, Ureteral Stent
- Trial name
- NCT05738304
- Testing
- Retrograde intrarenal surgery with external ureteral catheter, Retrograde intrarenal surgery with double J internal ureteral stent
- Where
- Egypt
- Volunteers
- 250 people
- Sponsor
- Al-Azhar University
Renal Calculi
External Physical Vibration Lithecbole(EPVL) Versus Traditional Row of Stone After Retrograde Intrarenal Surgery(RIRS)
The treatment of renal calculus by retrograde intrarenal surgery(RIRS) isn't able to eliminate stone completely, hastening fragments clearance just only rely on traditional expulsive methods such as high fluid intake ,increasing…
- Trial name
- NCT02645708
- Testing
- Retrograde Intrarenal Surgery, EPVL after RIRS
- Where
- China
- Volunteers
- 180 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Kidney Stone
Comparison of Efficacy of Intercostal Nerve Block vs Peritract Infiltration With 0.25% Bupivacaine in PCNL
Percutaneous nephrolithotomy (PCNL) is the preferred treatment for renal stones >2 cm or resistant to ESWL. Postoperative pain following this invasive surgery adds to the morbidity of patient which requires additional analgesia…
- Trial name
- NCT04835922
- Testing
- Intercostal Nerve Block, Peritract Infiltration
- Where
- Nepal
- Volunteers
- 60 people
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Large Renal Stone
A Comparative Study Between Anterior and Posterior Pyelotomy in Transperitoneal Laparoscopic Pyelolithotomy
Large renal pelvic stones are frequently managed with percutaneous nephrolithotomy (PCNL) but laparoscopic pyelolithotomy (LPL) can be an alternative procedure when performed by skilled surgeons to achieve excellent outcomes in…
- Trial name
- NCT06394219
- Testing
- traditional transperitoneal laparoscopic pyelolithotomy, modified transperitoneal laparoscopic pyelolithotomy
- Where
- Syria
- Volunteers
- 36 people
- Sponsor
- Damascus University
Kidney Stones, Nephrolithiasis
Retrograde Intrarenal Surgery (RIRS) With High-Power Laser and Flexible, Navigable Suction Access Sheath (FANS) vs Mini-Percutaneous Nephrolithotomy (miniPCNL) for 2-3 cm Renal Stones
This prospective cohort study aims to compare the safety and efficacy of retrograde intrarenal surgery combined with a high-power Holmium:YAG laser and flexible navigable suction access sheath versus mini-percutaneous…
- Trial name
- NCT07349992
- Testing
- Retrograde Intrarenal Surgery, Mini Percutaneous Nephrolithotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Necmettin Erbakan University
Ureteral Calculi
URSL Angle for Predicting Intraoperative Conversion
This international multicenter retrospective cohort study aims to externally validate the URSL Predictive Angle, a novel CT-derived morphometric parameter, as an imaging biomarker for predicting intraoperative conversion risk…
- Trial name
- URSL-PREDICT (NCT07561684)
- Volunteers
- 2,200 people
- Sponsor
- The First Hospital of Jilin University
Urolithiasis, Kidney Stone
Comparing Efficacy and Complication Between Prone Versus Prone-Flexed Position for Percutaneous Nephrolithotomy (PCNL)
Comparing Efficacy and Complication Between Prone Versus Prone-Flexed Position For Percutaneous Nephrolithotomy (PCNL)
- Conditions
- Urolithiasis, Kidney Stone, Complication
- Trial name
- NCT06624306
- Testing
- Prone PNL, Prone-flexed PNL
- Where
- Egypt
- Volunteers
- 85 people
- Sponsor
- Fayoum University Hospital
Urinary Stone, Renal Colic
Radiomics and Image Segmentation of Urinary Stones by Artificial Intelligence
Kidney stone disease causes significant morbidity, and stones obstructing the ureter can have serious consequences. Imaging diagnostics with computed tomography (CT) are crucial for diagnosis, treatment selection, and follow-up.
- Conditions
- Urinary Stone, Renal Colic, Obstruction Ureter, Urosepsis
- Trial name
- RISUS_AI (NCT06412900)
- Where
- Norway
- Volunteers
- 522 people
- Sponsor
- Oslo University Hospital
Cystinuria
TCUPS- Tolvaptan Use in Cystinuria and Urolithiasis: A Pilot Study
The goal of this research project is to establish that in short-term use, tolvaptan is a safe and potentially effective new therapy for cystinuria, by conducting a short-term pilot study of the safety and tolerability of this…
- Trial name
- TCUPS (NCT02538016)
- Testing
- Tolvaptan
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Caleb Nelson
Urolithiasis, Nephrolithiasis
Effect of Furosemide on ESWL Outcomes for Renal and Ureteral Calculi
The minimally-invasive extracorporeal shockwave lithotripsy (ESWL) procedure is generally considered the best first-line treatment option for most adults and children with nephrolithiasis, especially when the calculi are smaller…
- Conditions
- Urolithiasis, Nephrolithiasis, Urinary Calculi, Ureterolithiasis
- Trial name
- NCT05270421
- Testing
- Furosemide 40 mg, Conventional Treatment
- Where
- Iran
- Volunteers
- 500 people
- Sponsor
- Shiraz University of Medical Sciences
Renal Stone
Comparison of Surgical Outcomes Between MPCNL and RIRS
The objective of this research is to investigate the surgical outcomes of minimally invasive percutaneous nephrolithotomy(MPCNL) and retrograde intrarenal surgery (RIRS)for patients with renal stone larger than 1cm.
- Trial name
- NCT02067221
- Testing
- RIRS, MPCNL
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- Seoul National University Hospital
Flank Pain, Urinary Bladder, Overactive
Therapeutic Merit of Solifenacin in the Mitigation of Ureteral Stent-induced Pain and Lower Urinary Tract Symptoms
Most ureteral stent insertions follow ureteroscopy procedures for stone management. Stents are essentially designed to prevent the blockage of the ureter.
- Trial name
- NCT01381120
- Testing
- Solifenacin succinate treatment, Oxycodone and acetaminophen combination treatment
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- Barrie Urology Associates
Kidney Stone
Clinical Outcomes and Healthcare Economics of SOLTIVE Compared to Ho:YAG Laser in Urolithiasis
To compare intraoperative as well as postoperative outcomes of SOLTIVE Thulium laser compared to Ho:YAG laser for the treatment of urolithiasis.
- Trial name
- NCT04997668
- Testing
- SOLTIVE Thulium Fiber Laser, Ho:YAG Laser
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Kansas Medical Center