Clinical trials: Urogynecologic Surgery
Surgical Wound, Tissue Adhesion
Skin Closure With Tissue Adhesives vs. Subcuticular Suture After Robotic Urogynecologic Procedures
To compare skin closure via subcuticular suture versus tissue adhesive (Dermabond) in urogynecological robotic surgeries. The primary outcome is incision cosmesis at the 12 week follow up visit.
- Trial name
- NCT03891004
- Testing
- Subcuticular Skin Closure, Tissue Adhesives
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- St. John Hospital & Medical Center
Pain, Post-operative, Pneumoperitoneum
Does Trendelenburg Positioning During Pulmonary Recruitment Breaths Affect Post-laparoscopy Shoulder Pain
The goal of this clinical trial is to evaluate whether different positioning in the operating room during removal of laparoscopic surgical gas differs in post-surgery shoulder pain.
- Conditions
- Pain, Post-operative, Pneumoperitoneum, Urogynecologic Surgery
- Trial name
- NCT07631728
- Testing
- Pulmonary recruitment maneuver, Trendelenburg position
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ankita Gupta
Gender Identity Disorder of Adult, Voiding Disorders
Transgender Post-reassignment Urogynecologic Measures and Perceptions
The intent of this mixed methods study for transgender women after gender confirmation surgery is to characterize and subsequently create a validated screening questionnaire for postoperative urologic and pelvic floor symptoms.
- Conditions
- Gender Identity Disorder of Adult, Voiding Disorders, Sexual Dysfunction
- Trial name
- NCT03293771
- Testing
- Focus group interviews, Questionnaire packet
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Urinary Retention Postoperative, Patient Satisfaction
Patient Removal of Catheters After Urogynecologic Surgery
Management of postoperative urinary retention often requires the use of indwelling catheters. The purpose of this study is to see if patient removal of catheters at home is non-inferior to standard office removal.
- Trial name
- CARES (NCT04783012)
- Testing
- Catheter removal
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Opioid Use
Does a Non-Opioid Multimodal Pain (NOMO) Protocol Decrease Narcotic Use
The objective of this study is to evaluate narcotic use after implementation of a Non-Opioid Multimodal Pain (NOMO) protocol in patients who are undergoing a urogynecologic procedure.
- Trial name
- NCT05386069
- Testing
- NOMO Protocol
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Prisma Health-Upstate
Pelvic Organ Prolapse, Urinary Incontinence
Chlorhexidine vs. Iodine for Vaginal Preparation in Urogynecologic Procedures
This is a randomized controlled trial to determine if there is a difference between chlorhexidine gluconate and povidone iodine vaginal preparations for urogynecological surgery post operative infections.
- Conditions
- Pelvic Organ Prolapse, Urinary Incontinence, Pelvic Floor Disorders, Gynecologic Disease
- Trial name
- CLNUP (NCT04048356)
- Testing
- Vaginal scrub, to be applied vaginally and perineally immediately prior to surgery.
- Where
- United States
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Obstructive Defecation Syndrome, Postoperative Constipation
PEG3350 vs Senna After Urogyn Surgery
The goal of this study is to evaluate whether polyethylene glycol 3350 (PEG3350) versus senna is better at relieving postoperative constipation after urogynecologic surgery.
- Trial name
- NCT06825260
- Testing
- Senna, Polyethylene glycol 3350
- Where
- United States
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- St. Joseph's Health, New York
Functional Disorder of Intestine
Bowel Function After Minimally Invasive Urogynecologic Surgery
The purpose of this study is to assess the effect of a standardized postoperative bowel regimen of over-the-counter medications in subjects undergoing minimally invasive urogynecologic surgery.
- Trial name
- NCT01044212
- Testing
- Docusate, Bowel medications
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Urinary Retention Postoperative, Postoperative Urinary Tract Infection
Early Patient Removal of Urinary Catheters After Urogynecologic Surgery
Management of postoperative urinary retention often requires the use of indwelling catheters. In a previous study, the investigators determined that patient removal of catheters at home is non-inferior to standard office removal…
- Conditions
- Urinary Retention Postoperative, Postoperative Urinary Tract Infection, Catheter Site Pain
- Trial name
- CARES2 (NCT06344884)
- Testing
- Early catheter removal
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Pelvic Organ Prolapse, Gynecologic Disorders
Comparison of Learning Curves for Two Different Techniques in Vaginal Hysterectomy
Randomized prospective monocentric interventional study to compare learning curves for traditional vaginal hysterectomy and vaginal hysterectomy performed by bipolar coagulation comparing short-term outcomes for both procedures.
- Conditions
- Pelvic Organ Prolapse, Gynecologic Disorders, Surgery
- Trial name
- NCT06220253
- Testing
- vaginal hysterectomy by bipolar vessels sealing, vaginal hysterectomy by traditional technique
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Prolapse, Stress Urinary Incontinence
Telephone Intervention to Increase Patient Preparedness and Satisfaction Trial (TIPPS): A Randomized Control Trial
Surgical preparedness improves patient satisfaction and perioperative outcomes. In urogynecology, interventions to increase preoperative patient preparedness have not been adequately studied.
- Trial name
- TIPPS (NCT03890471)
- Testing
- Preoperative telephone call three days before surgery
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Postoperative Pain, Opioid Use
A Randomized-controlled Trial of Post-operative Opiate Quantities After Urogynecologic Surgery
This is a randomized controlled trial to determine the effect of decreased post-operative prescriptions of opiate medications after urogynecologic surgery.
- Trial name
- NCT03319277
- Testing
- Decreased opiate prescription, Routine opiate prescription
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Pain, Postoperative, Postoperative Pain, Acute
Impact of Preoperative Opioid-free Multimodal Analgesia on Time to Trial of Void in Ambulatory Urogynecologic Surgeries
This is a double-arm randomized control trial evaluating the impact of preoperative opioid-free analgesia on time to trial of void in ambulatory urogynecologic surgeries.
- Trial name
- NCT06379425
- Testing
- Acetaminophen, Celecoxib, Gabapentin
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Pelvic Organ Prolapse (POP), Postoperative Pain
Suzetrigine Following Urogynecologic Surgery: Investigation of Postoperative Pain Management
The goal of this clinical trial is to determine whether suzetrigine, when added to standardized multimodal postoperative analgesia improves pain control and reduces opioid consumption after apical suspension surgery for pelvic…
- Conditions
- Pelvic Organ Prolapse (POP), Postoperative Pain, Urogynecology
- Trial name
- SUSI (NCT07856654)
- Testing
- Suzetrigine
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Aditi Talkad
Urinary Retention Postoperative, Voiding Disorders
Optimization of Spontaneous Postoperative Trial of Void Among Women
Trial of void (TOV) is a diagnostic test performed on all women who undergo prolapse repair or incontinence surgery, due to the importance of diagnosing postoperative urinary retention (POUR).
- Trial name
- OPTION (NCT04010656)
- Testing
- PVR-based self-catheterization
- Where
- United States
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Postoperative Pain
Efficacy of Extended-Release Liposomal Bupivacaine for Post-Operative Urogynecologic Surgery
To study post-operative efficacy of Exparel® for pain control in patients undergoing any Urogynecology surgery involving the posterior vaginal wall using a randomized, double-blinded placebo controlled trial.
- Trial name
- NCT02287246
- Testing
- Extended-Release liposomal bupivacaine (Exparel), Normal saline
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center