Clinical trials: Urological Surgeries
Pelvic Organ Prolapse, Urinary Incontinence
Continence After Vaginal Prolapse Surgery
Urinary incontinence after surgical correction of pelvic organ prolapse (POP) could occur. This is a condition that decreases both patients' satisfaction and quality of life.
- Trial name
- NCT05312047
- Testing
- Pelvic organ prolapse surgery
- Where
- 14 sites in Spain
- Volunteers
- 609 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Urinary Incontinence
Assessment of Two Postoperative Techniques Used to Predict Voiding Efficiency After Gynecologic Surgery
After gynecologic surgery, it may be difficult to void (urinate). This problem is usually short-term with normal function returning within a few days to a few weeks.
- Trial name
- NCT00392210
- Testing
- Voiding Trial
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Urinary Stress Incontinence
Comparative Study of PDVF and Polypropylene Transobturator Suburethral Tapes
This study evaluates the effectiveness and complications of polyvinylidene fluoride (PVDF) and polypropylene (PP) transobturator suburethral tapes (TOTs) in the treatment of female stress urinary incontinence.
- Trial name
- NCT02886520
- Testing
- PVDF transobturator tape, Polypropylene transobturator tape
- Where
- 9 sites in Spain
- Volunteers
- 286 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Pregabalin on Catheter Related Bladder Discomfort
Effect of Pregabalin Administration on Catheter- Related Bladder Discomfort in Urological Surgical Operations
The aim of this study is to assess the effect of pregabalin administration on catheter-related bladder discomfort (CRBD). The study group includes patients that are about to be subjected to urological operations because of the…
- Trial name
- NCT03229668
- Testing
- Pregabalin Oral Capsule [Lyrica] 75mg, Pregabalin Oral Capsule [Lyrica] 150 mg
- Where
- 2 sites in Greece
- Volunteers
- 78 people
- Sponsor
- Saint Savvas Anticancer Hospital
HoLEP, Trifecta Achievement
Predictors of Trifecta Achievement After HoLEP
Holmium laser enucleation of the prostate (HoLEP) is a surgical treatment option for men experiencing bothersome lower urinary tract symptoms due to an enlarged prostate.
- Conditions
- HoLEP, Trifecta Achievement, Urinary Incontinence Following Surgical Procedure, Clavien Dindo Surgical Complication Scale
- Trial name
- ReMIUS-BPO (NCT07429994)
- Testing
- Transurethral Holmium Laser Enuclation of the Prostate
- Where
- Turkey (Türkiye)
- Volunteers
- 604 people
- Sponsor
- Ondokuz Mayıs University
Lower Urinary Tract Symptoms, Voiding Dysfunction
Urodynamics for Prostate Surgery Trial; Randomised Evaluation of Assessment Methods
Background and study aims: The prostate gland sits around the exit of the bladder in men. As men get older, the prostate grows, and this can narrow the exit from the bladder, so that there is restriction of flow.
- Conditions
- Lower Urinary Tract Symptoms, Voiding Dysfunction, Benign Prostate Obstruction, Detrusor Underactivity
- Trial name
- UPSTREAM (NCT02193451)
- Testing
- Urodynamics, Usual care
- Where
- United Kingdom
- Volunteers
- 820 people
- Sponsor
- North Bristol NHS Trust
Stress Urinary Incontinence, Surgical Incision
Use of a Dual-agent Local Analgesic (Bupivacaine-meloxicam) for Abdominal Incisions in Patients Undergoing Retropubic Mid-urethral Sling Surgery
This study will compare the use of a dual-agent local analgesic (bupivacaine-meloxicam) for abdominal incisions in patients undergoing retropubic mid-urethral sling surgery to see if narcotic usage and pain are impacted.
- Conditions
- Stress Urinary Incontinence, Surgical Incision, Pain Vulva
- Trial name
- NCT05702827
- Testing
- Bupivacaine-Meloxicam
- Where
- 2 sites in United States
- Volunteers
- 148 people
- Sponsor
- TriHealth Inc.
Stress Urinary Incontinence
Urodynamic Study and Stress Incontinence
A trial to answer the debatabal question about the role of urodynamic study in surgical treatment for stress urinary incontinence.
- Trial name
- NCT03300973
- Testing
- sling surgery
- Where
- Egypt
- Volunteers
- 125 people
- Sponsor
- Kasr El Aini Hospital
Hemostasis
Post-Market Evaluation of HEMOBLAST™ Bellows in Open Gynecological, Urological, ENT, Head, Neck, and Vascular Surgeries
A prospective, multi-center, multi-national single arm study to evaluate the performance and safety of HEMOBLAST™ Bellows in open gynecological, urological, ENT and head and neck, and vascular surgery.
- Trial name
- NOBLE-Open (NCT03873168)
- Testing
- HEMOBLAST™ Bellows
- Where
- 9 sites in Austria, France and 1 more
- Volunteers
- 64 people
- Sponsor
- Biom'Up France SAS
Urinary Incontinence
Polyacrylamide Injection in Patients Ineligible for Surgery
Transurethral injection using polyacrylamide hydrogel (Bulkamid®, Contura A/S, Denmark) is an established treatment for stress urinary incontinence.
- Trial name
- NCT02776423
- Testing
- Bulkamid
- Volunteers
- 81 people
- Sponsor
- Karolinska Institutet
Incontinence, Urinary Stress, Prostate Cancer
Effect of Text Message Reminders on M-ISI Score After Prostate Surgery
The purpose of this study is to compare post-prostatectomy incontinence via Michigan Incontinence Score Index in patients receiving daily text message reminders for pelvic floor exercises when compared to those not receiving text…
- Conditions
- Incontinence, Urinary Stress, Prostate Cancer, Benign Prostate Hyperplasia
- Trial name
- TextMsgM-ISI (NCT07071207)
- Testing
- Text message reminders
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- University of Rochester
Urinary Retention, Pelvic Organ Prolapse
Urinary Catheter Self-Discontinuation After Urogynecology Surgery
The goal of this randomized clinical trial is to determine if removal of transurethral urinary catheters by patients at home is as safe as catheter removal in the office following urogynecologic surgery.
- Conditions
- Urinary Retention, Pelvic Organ Prolapse, Stress Urinary Incontinence, Catheter Related Complication
- Trial name
- CATH (NCT05860634)
- Testing
- Catheter self-discontinuation
- Where
- 4 sites in United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Stress Urinary Incontinence
Impact of Unrestrictive Exercise Following Mid-Urethral Sling Surgery
To determine the impact of unrestricted postoperative activity on intermediate- and long-term continence outcomes of mid-urethral sling surgery in women with stress urinary incontinence.
- Trial name
- NCT02316275
- Testing
- No post-operative activity restrictions, Standard post-operative activity restriction
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Cedars-Sinai Medical Center
Frail Elderly Syndrome, Anesthesia Complication
Frailty, Anesthesia and Complications.
Objectives: To assess the prevalence of frailty in patients older than 70 y/o in nephrourologic surgery. To study if preoperative frailty is an independent predictor of immediate postoperative complications, after 30 days, 6…
- Conditions
- Frail Elderly Syndrome, Anesthesia Complication, Complication of Surgical Procedure, Postoperative Delirium
- Trial name
- FRAC (NCT04264351)
- Where
- Spain
- Volunteers
- 413 people
- Sponsor
- Fundacio Puigvert
Prostatic Hyperplasia, Bladder Cancer
Information Improvement for Surgical Patients Through Portable Video Media
The aim of this study is to evaluate the comprehension of the Informed consent with the Standard Verbal Communication (SVC) versus Portable Video Media (PVM).
- Trial name
- NCT02846467
- Testing
- Informed consent trough a portable video media, Written informed consent
- Where
- Spain
- Volunteers
- 193 people
- Sponsor
- Hospital Universitario Puerto Real
Urinary Incontinence, Pelvic Organ Prolapse
Voiding Assessment Based on Minimum Spontaneous Void of 150 mL Compared to Retrograde Fill Method After Female Pelvic Floor Reconstructive Surgery
This study will compare voiding assessment based on a minimum spontaneous voided volume of 150 cc with the standard retrograde fill approach in women after pelvic floor procedures.
- Trial name
- NCT03539107
- Testing
- Retrograde bladder fill, spontaneous void
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Yale University
Pediatric Kidney Disease
The Impact of Meditation on Anxiety and Post-Operative Pain in Pediatric Patients Undergoing Urological Surgery
1. The aim of this study is to assess anxiety in pediatric patients preoperatively, perioperatively, and postoperatively and whether meditation reduces anxiety in the days before, during, and after the surgery. 2.
- Trial name
- NCT06858267
- Testing
- PeSSKi questionnaire survey, Meditation Video
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Augusta University
Hemodynamic Instability
Effect of Prilocaine vs Bupivacaine on Hemodynamics in Spinal Anesthesia for Geriatric Patients
Data comparing prilocaine vs bupivacaine in equipotent doses in the elderly are lacking; therefore, the study will compare the effect of prilocaine vs bupivacaine on hemodynamics in spinal anesthesia for geriatric patients…
- Trial name
- NCT06165679
- Testing
- Prilocaine, Bupivacaine
- Where
- Egypt
- Volunteers
- 112 people
- Sponsor
- Cairo University
Urinary Incontinence
Patient Satisfaction Survey of Non-surgical Urinary Incontinence Treatment
The purpose of this study is to identify self-reported wellness following nonsurgical treatment of stress urinary incontinence. This will be done by correlating the response of "yes" on the patient acceptable symptom state (PASS)…
- Trial name
- NCT04064970
- Testing
- patient acceptable symptom state (PASS)
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- University of Rochester
Bladder Cancer, Prostate Cancer
Robot-assisted Urological Surgeries Using the MicroHand S Robot
A single-blinded, prospective randomized parallel controlled clinical trial is designed and will be conducted from July 2022 to November 2023 (anticipated).
- Conditions
- Bladder Cancer, Prostate Cancer, Renal Cancer
- Trial name
- NCT05462392
- Testing
- robot-assisted surgery
- Where
- China
- Volunteers
- 136 people
- Sponsor
- The Affiliated Hospital of Qingdao University