Clinical trials: Usual Care
Intervention-carbon Monoxide Alarm + Educational Tool, Control- Usual Care Flyer on Carbon Monoxide
Emergency Department Brief Intervention to Increase Carbon Monoxide Detector Use
Carbon Monoxide (CO) exposure kills and injures thousands of children and families each year. Although there is growing concern about the need to increase carbon monoxide detector use, little is known about how best to do so…
- Trial name
- ProjectCODE (NCT00959478)
- Testing
- Educational Tool & Carbon Monoxide Alarm
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Lara McKenzie
Acute Kidney Injury
Comparison of Early Proton Pump Inhibitor Initiation Versus Usual Care on Acute Kidney Injury in Hemorrhagic Shock Patients
The investigators propose a single-center, randomized, controlled trial to determine whether early initiation of proton pump inhibitor (PPI), pantoprazole, will decrease acute kidney injury (AKI) for trauma patients presenting…
- Trial name
- Trauma AKI PPI (NCT06531642)
- Testing
- Protonix (Pantoprazole) 40 mg q 12 hrs for 2 days, Protonix (pantoprazole) 40 mg q 24 hrs for 2 days
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
PTSD, Depression
Participatory System Dynamics vs Usual Quality Improvement: Staff Use of Simulation as an Effective, Scalable and Affordable Way to Improve Timely Mental Health Care?
Evidence-based VA care is best for meeting Veterans' mental health needs, such as depression, PTSD and opioid use disorder, to prevent suicide or overdose. But some key evidence-based practices only reach 3-28% of patients.
- Conditions
- PTSD, Depression, Opioid Use Disorder
- Trial name
- NCT04208217
- Testing
- Modeling to Learn (MTL), Usual quality improvement (QI)
- Where
- United States
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Breast Cancer, Ovarian Cancer
A Study Of TeleGenetics Versus Usual Care To Increase Access To Cancer Genetic Services
The goal of this research is to evaluate the relative advantage of remote counseling over usual care in community health practices without access to genetic services.
- Conditions
- Breast Cancer, Ovarian Cancer, Colorectal Cancer
- Trial name
- NCT02517554
- Testing
- Penn genetic counselors provides counseling and test results disclosure by videoconferene to patient at community site, Penn genetic counselor provides counseling and test results disclosure by telephone to patient at community site, Patient receives written information on how to find genetic services in their area
- Where
- 7 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
Mental Health Issue
Determining the Effectiveness of Working Out Dads to Reduce Mental Health Difficulties in Fathers of Young Children
This is an individually randomised trial, where Working Out Dads (WOD) will be delivered as a group intervention. Participants will be randomised to one of two groups: either WOD or usual care.The trial aims to test the…
- Trial name
- WOD (NCT04813042)
- Testing
- Working Out Dads, Usual care
- Where
- Australia
- Volunteers
- 293 people, healthy volunteers welcome
- Sponsor
- Murdoch Childrens Research Institute
Falls
Promoting Physical Activity in the Over 65s
The aim of the project is to evaluate the delivery, impact and cost effectiveness of a community based exercise programme (FaME); compared to a home based exercise programme (OEP) supported by similarly aged mentors; compared…
- Trial name
- ProAct65+ (NCT00726531)
- Testing
- Otago Exercise Programme, Fame, Treatment As Usual
- Where
- 2 sites in United Kingdom
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University College, London
Spinal Cord Injury, Autonomic Dysreflexia
Treatment of Post-SCI Hypotension
While treatment strategies for OH have been identified for use in persons with acute SCI, the field of SCI medicine lacks a gold standard for treatment thresholds and well-defined outcome parameters.
- Conditions
- Spinal Cord Injury, Autonomic Dysreflexia, Orthostatic Hypotension, Baroreceptor Integrity
- Trial name
- NCT02919917
- Testing
- Midodrine Hydrochloride
- Where
- 2 sites in United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Myopia
Early Intervention for High Risk Premyopic Children
The purpose of this research project is to add evidence of pharmacological (0.025% atropine) and optical (Defocus Integrated Multiple Segments Triple Enhanced Design spectacle lenses ) approaches for myopia prevention among…
- Trial name
- NCT07863713
- Testing
- 0.025% atropine eye drops, DIMS TED
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University Hospital
Management of Anticoagulation
Improved Time in Therapeutic Range With Patient Self-Testing of Their INR Compared to Usual Care
Patients who receive a mechanical heart valve to replace a diseased heart valve must take an anticoagulation medicine the rest of their lives, and monitor their level of anticoagulation.
- Trial name
- NCT00703963
- Testing
- INRatio monitor by Hemosense, Usual Care
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Colorectal Cancer, Healthy, no Evidence of Disease
Genetic Epidemiology Risk Assessment Program or Usual Care in Colorectal Cancer Screening for Healthy Participants
RATIONALE: The Genetic Epidemiology and Risk Assessment program may be more effective than usual care in increasing the number of healthy participants who regularly receive screening for colorectal cancer.
- Trial name
- NCT00478309
- Testing
- counseling intervention, educational intervention
- Where
- United States
- Volunteers
- 697 people, healthy volunteers welcome
- Sponsor
- Fox Chase Cancer Center
Fluoride Varnish and Oral Health Promotion, Usual Care
Preventing Caries in Preschoolers: Testing a Unique Service Delivery Model in American Indian Head Start Programs
An intensive intervention of specially trained paraprofessionals, called community oral health specialists (COHS), administering on a quarterly basis for 2 years fluoride varnish and oral health promotion education, compared to…
- Trial name
- NCT01116739
- Testing
- Fluoride varnish, Oral health education, Dental services delivered by the Indian Health Service.
- Where
- United States
- Volunteers
- 2,060 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Dementia, Accidental Falls
The TACIT Trial: TAi ChI for People With demenTia
This is a three-centre parallel group randomised controlled trial with an embedded process evaluation and intervention pilot phase (details not provided in this summary).
- Trial name
- TACIT (NCT02864056)
- Testing
- Tai Chi
- Where
- 3 sites in United Kingdom
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Bournemouth University
Toileting in Adults With Impaired Functional Status, Caregiver Burden for Those Who Care for Adults With Impaired Functional Status
Quality of Life in Adults Impaired Functioning - A Randomized Controlled Trial of Bidet vs Usual Toileting
Our expectations (hypotheses) are: Primary outcome 1. Regular bidet use will improve quality of life around elimination in adults with impaired functional status.
- Conditions
- Toileting in Adults With Impaired Functional Status, Caregiver Burden for Those Who Care for Adults With Impaired Functional Status, UTI in Adults With Impaired Functional Status
- Trial name
- NCT02042157
- Testing
- Bidet use, Regular toileting
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Stanford University
Anxiety
Comparison of Usual Care and Distraction (Tablet) in Children 3-5 Years Old
Randomized control trial comparing usual care and distraction (tablet) on anxiety, emergence delirium, sedation/agitation, and vomiting in children 3-5 years old
- Trial name
- NCT05368961
- Testing
- Distraction, Usual care
- Where
- United States
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Caregivers, Mindfulness
Tele-Mindfulness for Dementia's Family Caregivers: a Randomized Trial With a Usual Care Control Group
Family caregivers were recruited through a combinations of strategies including a larger caregiving project and its partners, memory clinics, community outreach, online advertisement, flyers and brochures and word of mouth.
- Trial name
- NCT04416529
- Testing
- Tele-MBCT
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Knee Arthropathy
A Pilot Feasibility Study Comparing Smartphone Home-based Rehabilitation Program Against the Usual Hospital and Outpatient Physiotherapy Care on Clinical and Cost Effectiveness for Total Knee Replacement Patients
Knee osteoarthritis (OA) is a common, chronic, and costly condition whilst total knee replacement (TKR) is a common orthopaedic surgical intervention.
- Trial name
- NCT06248034
- Testing
- Smartphone application with tele-monitoring rehabilitation, Hospital-based rehabilitation program
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Modified DECIDE Intervention, Treatment as Usual Care Group
The DECIDE Parent-Provider Intervention
The DECIDE Parent-Provider Intervention is designed to support parents caring for adolescents who are receiving treatment for Disruptive, Impulse-Control, and Conduct disorders.
- Trial name
- NCT04445155
- Testing
- Modified DECIDE Parent and Provider Intervention
- Where
- 5 sites in United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Indiana University
Accidental Falls
Playware Technology for Balance Training
This study evaluates the use of Playware technology for balance training. Falling among elder is a costly problem. Research shows that training can help prevent falls.
- Trial name
- IMT (NCT02496702)
- Testing
- Training on Interactive Modulare Tiles
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Technical University of Denmark
Gout Initiating Urate-loweringUrate-lowering Therapy, Gout Arthritis
HLA-B*58:01-Guided Therapy for Gout: Effectiveness, Safety, and Cost-Effectiveness
Severe cutaneous adverse reactions (SCARs), such as Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) and drug reaction with eosinophilia and systemic symptoms (DRESS), are rare but life-threatening complications that…
- Conditions
- Gout Initiating Urate-loweringUrate-lowering Therapy, Gout Arthritis, Gout and Hyperuricemia
- Trial name
- HLA-SCREEN (NCT07369622)
- Testing
- HLA-B*58:01 Genotyping, Allopurinol Tablet, Febuxostat
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Haiphong University of Medicine and Pharmacy
COVID-19
Specimen Collection Study From Coronavirus Disease 2019 (COVID-19) Vaccinated Adults and Adolescents
This is a specimen collection study intended to generate a biological specimen repository of samples from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) naïve adults and adolescents ≥12 years old who will receive…
- Trial name
- CoVacSpec (NCT05252910)
- Where
- 32 sites in United States, Colombia and 5 more
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Pharm-Olam, LLC