Clinical trials: Uterovaginal Prolapse
Pelvic Organ Prolapse
Vaginally Assisted Laparoscopic Hysteropexy Versus Vaginal Hysterectomy
Utero-vaginal prolapse is a common, often disabling, condition experienced by women of varying ages. The traditional surgical treatment for utero-vaginal prolapse often includes vaginal hysterectomy and anterior or posterior…
- Trial name
- NCT03436147
- Testing
- POP-Q
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Uterovaginal Prolapse, Urinary Incontinence
Use of Artificial Intelligence by Urogynecologic Patients
The goal of this clinical trial is to learn about how Urogynecology patients use Artificial Intelligence (AI) Chatbots like ChatGPT, and how it affects healthcare decision making.
- Conditions
- Uterovaginal Prolapse, Urinary Incontinence, Lower Urinary Tract Symptoms
- Trial name
- NCT06481436
- Testing
- Use of ChatGPT
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Hartford Hospital
Pelvic Organ Prolapse
The Purpose of This Study is to Look at Pelvic Support Problems, Also Commonly Known as Pelvic Organ Prolapse
FemmeJock is a pelvic floor support system developed by pelvic floor physiotherapists for patients with pelvic organ prolapse in order to ameliorate symptoms of pelvic floor pressure and discomfort.
- Trial name
- NCT00964197
- Testing
- FemmeJock
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Rectocele; Female, Rectocele and Incomplete Uterine Prolapse
3D vs 2D-laparoscopy for Rectocele and Rectal Prolapse Correction: a Prospective, Randomized, Single Center Study
The aim is to compare proximate and remote results of 3D and conventional 2D laparoscopic interventions in terms of efficacy and safety in treatment of symptomatic rectocele and rectal prolapse.
- Conditions
- Rectocele; Female, Rectocele and Incomplete Uterine Prolapse, Rectocele and Complete Uterovaginal Prolapse, Rectal Prolapse
- Trial name
- LARC (NCT04817150)
- Testing
- Laparoscopic ventral mesh rectopexy
- Where
- Russia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alexander Khitaryan
Pelvic Organ Prolapse
Vaginal Uphold Hysteropexy and Laparoscopic Sacral Hysteropexy for the Treatment of Uterovaginal Pelvic Organ Prolapse
The purpose of this study is to evaluate surgical success or failure one year after surgery for pelvic organ prolapse.
- Trial name
- VAULT (NCT01377142)
- Testing
- Laparoscopic sacral hysteropexy, Vaginal mesh hysteropexy
- Where
- 8 sites in United States, Canada
- Volunteers
- 148 people
- Sponsor
- The Cleveland Clinic
Uterovaginal Prolapse, Prolapse of Vaginal Vault After Hysterectomy
Compare Sacrospinous Fixation Versus High Uterosacral Ligament Fixation for Uterus Vaginal Prolapse III/IV
The purpose of this study is to compare the vaginal sacrospinous colpopexy and high uterosacral colpopexy in the treatment of genital prolapse grade III/IV in women with uterus.
- Conditions
- Uterovaginal Prolapse, Prolapse of Vaginal Vault After Hysterectomy, Complete Tear, Sacrospinous Ligament, Uterosacral Ligament; Rupture
- Trial name
- NCT01347021
- Testing
- sacrospinous colpopexy versus high uterosacral colpopexy
- Where
- Brazil
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Vaginal Hysterectomy, Laparoscopic Supracervical Hysterectomy
Vaginal Hysterectomy vs Supracervical Hysterectomy at the Time of Sacrocolpopexy
The primary objective of the proposed study is to determine the difference in surgical time between minimally invasive (laparoscopic) sacrocolpopexy performed with concurrent vaginal hysterectomy versus laparoscopic supracervical…
- Trial name
- ColoplastLSC (NCT04797585)
- Testing
- Laparoscopic supracervical hysterectomy, Vaginal hysterectomy
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- The Cleveland Clinic
Pelvic Organ Prolapse, Uterovaginal Prolapse
Absorbable Suture vs Permanent Suture in Sacrospinous Ligament Suspension
Sacrospinous ligament suspension (SSLS) was first described in 1958. It is commonly performed for correction of apical prolapse. A combination of delayed absorbable and/or permanent sutures are commonly used for the procedure.
- Conditions
- Pelvic Organ Prolapse, Uterovaginal Prolapse, Vaginal Vault Prolapse, Cystocele
- Trial name
- NCT05688059
- Testing
- Absorbable Suture and Permanent Suture
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Atlantic Health System
Prolapse; Female, Prolapse Uterovaginal
Pragmatic Evaluation of Performance and Safety of the Anchorsure® Transvaginal Device for Surgical Treatment of Apical Prolapse in Women
Pelvic Organ Prolapse affects 50% of parous women, and apical prolapse is one of the most common types of prolapse. Treatment for apical prolapse ranges from observation, non-surgical treatment or surgical repair.
- Conditions
- Prolapse; Female, Prolapse Uterovaginal, Prolapse; Cervix
- Trial name
- APAS (NCT05836844)
- Testing
- The Anchorsure System®
- Where
- 4 sites in France
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Pelvic Organ Prolapse, Cystocele
Study Comparing Transobturator Cystocele vs. Anterior Vaginal RepairS
Surgical correction of the prolapse in the anterior compartment remains one of the major challenges in urogynecology. Paravaginal defect in level II of vaginal fixation results in the majority of cystoceles.
- Conditions
- Pelvic Organ Prolapse, Cystocele, Cystocele and Incomplete Uterovaginal Prolapse
- Trial name
- STARS (NCT05602246)
- Testing
- Transobturator cystocele repair, Anterior colporrhaphy
- Where
- 8 sites in Czechia, Slovakia
- Volunteers
- 592 people
- Sponsor
- Charles University, Czech Republic
Uterovaginal and Vaginal Vault Prolapse
A New Technique for Sacrospinous-Sacrotuberous Fixation for the Treatment of Uterovaginal and Vaginal Vault Prolapse
This prospective interventional randomized controlled trial is conducted to compare a new technique for Sacrospinous-Sacrotuberous fixation with the traditional sacrospinous ligament fixation technique for treatment of…
- Trial name
- NCT03487328
- Testing
- Sacrospinous-Sacrotuberous fixation
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Uterine Prolapse
Patient-Centered Outcomes in the Surgical Treatment of Uterovaginal Prolapse
The purpose of this study is to compare two types of surgery for the treatment of uterovaginal prolapse to determine which surgery works best from a patient's perspective and has the lowest number of short-term and long-term…
- Trial name
- PREMIER (NCT05063331)
- Testing
- Minimally invasive supracervical hysterectomy and sacrocolpopexy (MI-SCH+SCP), Vaginal hysterectomy with uterosacral ligament suspension (TVH+USLS)
- Where
- 7 sites in United States
- Volunteers
- 300 people
- Sponsor
- University Hospitals Cleveland Medical Center
Urinary Dysfunction, Vaginal Prolapse
Effects of Kegel Ball and Pelvic Floor Exercises on Sexual Function, Unrınary Incontinence and Quality of Life in Women
Urinary incontinence and sexual dysfunction are common conditions that can significantly impact quality of life. Although surgical and medical treatments are available, many individuals seek non-invasive alternatives.
- Conditions
- Urinary Dysfunction, Vaginal Prolapse, Sexual Function Scores, Kegel Exercises
- Trial name
- NCT07048145
- Testing
- Vaginal Kegel Exercise Ball, Pelvic Floor Muscle Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- sahra sultan kara
Uterovaginal Prolapse, Hysteropexy
Laparoscopic/Robotic-assisted Hysteropexy Versus Vaginal Hysterectomy for the Treatment of Uterovaginal Prolapse
objective: aimed to compare laparoscopic/robot-assisted hysteropexy with vaginal hysterectomy for uterine prolapse prospective randomized clinical trial patient 1. 60yrs or more women and 2.
- Trial name
- PROLAPSE (NCT02877407)
- Testing
- patient who undergo laparoscopic/robotic-assisted hysteropexy, patient who undergo vaginal hysterectomy
- Where
- South Korea
- Volunteers
- 146 people
- Sponsor
- Seoul National University Hospital
Prolapse; Female, Prolapse Genital
Transvaginal Human Acellular Dermal Matrix for Prolapse Treatment
This is a randomised study in which we compare the effectiveness of three different procedures in mending symptomatic anterior and apical prolapse in patients who are candidates to receive surgery.
- Conditions
- Prolapse; Female, Prolapse Genital, Prolapse Uterovaginal
- Trial name
- NCT06404931
- Testing
- Vaginal hysterectomy plus matrix reinforcement and sacrospinous fixation with Anchorsure® device, Vaginal hysterectomy plus anterior colporrhaphy, Vaginal hysterectomy plus sacrospinous fixation with Anchorsure® device
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Hospital Mutua de Terrassa
Uterovaginal Prolapse, Ureteral Injury
Ureteral Patency After Uterosacral Ligaments Suspension
Uterosacral ligament suspension (USLS) is a commonly performed procedure used to correct prolapse of the vaginal apex. The procedure consists of approximating the vaginal apex to the uterosacral ligaments with a series of sutures…
- Conditions
- Uterovaginal Prolapse, Ureteral Injury, Surgery--Complications
- Trial name
- NCT05477043
- Testing
- Transabdominal ultrasound and cistoscopy
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Milano Bicocca
Uterovaginal Prolapse
Study of Uterine Prolapse Procedures - Randomized Trial
The primary purpose of this randomized clinical trial is to compare the effectiveness and safety of two transvaginal apical suspension strategies for uterovaginal prolapse: a mesh augmented hysteropexy versus vaginal hysterectomy…
- Trial name
- SUPeR (NCT01802281)
- Testing
- Uterosacral ligament suspension, Uphold® LITE
- Where
- 8 sites in United States
- Volunteers
- 183 people
- Sponsor
- NICHD Pelvic Floor Disorders Network
Prolapse Uterovaginal, Prolapse Bladder
Laparoscopic Central and Anterior Compartment Prolapse Surgery: A Meshless Sacrocolpopexy Technique
Mesh is widely applied in the abdominal approach to pelvic organ prolapse surgery, and sacrocolpopexy-sacrohysteropexy is the gold standard application, particularly for central compartment abnormalities.
- Conditions
- Prolapse Uterovaginal, Prolapse Bladder, Laparoscopy
- Trial name
- NCT05558852
- Testing
- Laparoscopic Meshless Sacrocolpopexy Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Prolapse Genital, Prolapse Uterovaginal
Posterior Mesh Fixation at the Levator Ani Level in Apical Pelvic Organ Prolapse
This is a prospective, randomized, multicenter, non-inferiority trial including women with stage II-IV apical pelvic organ prolapse (POP), classified according to the POP-Q system.
- Conditions
- Prolapse Genital, Prolapse Uterovaginal, Prolapse; Female
- Trial name
- FIMEA (NCT07194343)
- Testing
- Laparoscopic colposacropexy with levator ani muscle mesh fixation, Simplified modification of laparoscopic colposacropexy
- Where
- 6 sites in Spain
- Volunteers
- 190 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau