Clinical trials: VATS
Pain, Postoperative
Preventing pAIn With NMDA Antagonists - Steroids in Thoracoscopic lObectomy Procedures (PAIN-STOP) Pilot Trial
The objective of the PAIN-STOP trial is to assess the feasibility of a larger randomized controlled trial (RCT) evaluating NMDA antagonists and IV steroids, as compared to placebo, in decreasing the chances of clinically…
- Trial name
- PAIN-STOP (NCT02950233)
- Testing
- NMDA active, Steroid active
- Where
- 2 sites in United States, Canada
- Volunteers
- 27 people
- Sponsor
- Population Health Research Institute
Lung Neoplasms, Lung Surgery
Chest dRain rEmoval intrAoperatively afTer thoracOscopic Wedge Resection
Chest drain is used routinely after lung surgery. Despite preliminary studies demonstrate the feasibility and safety of intraoperative chest drain removal, these are either retrospective or mainly concerning benign disease.
- Conditions
- Lung Neoplasms, Lung Surgery, Enhanced Recovery After Surgery, Fast-track Surgery
- Trial name
- CREATOR (NCT05358158)
- Testing
- Intraoperative air leak test, Intraoperative chest drain removal, Standard chest drain placement
- Where
- 2 sites in Denmark
- Volunteers
- 94 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Regional Anesthesia, Thoracic Surgery
Serratus Anterior Plane Block: Post-operative Analgesia in Video-assisted Thoracic Surgery
The objective of the study is to compare the efficacy of the Serratus Anterior Plane block (SPB) realised in its deep plane, with a multi-holed catheter in place for twenty four hours, to a standard intravenous analgesia for…
- Conditions
- Regional Anesthesia, Thoracic Surgery, Post-operative Pain, Post-operative Chronic Pain
- Trial name
- Serrathos (NCT03277391)
- Testing
- Serratus anterior plane block, patient-controlled analgesia
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Université Libre de Bruxelles
Thoracic, Pain, Postoperative
Intercostal Nerve Block for Pain Management After Uniportal Video-assisted Thoracoscopic Surgeries
The goal of this clinical trial is to compare the safety and effectiveness of the three intercostal nerve blocks used in pain management in uniportal (one port) thoracoscopic surgeries: internal intercostal nerve blocks (ICNB)…
- Conditions
- Thoracic, Pain, Postoperative, Analgesia, Satisfaction, Patient
- Trial name
- VATS (NCT06838026)
- Testing
- External Intercostal Nerve Block, Internal Intercostal Nerve Block, Intercostal Catheter
- Where
- 2 sites in Palestinian Territories
- Volunteers
- 90 people
- Sponsor
- Al-Quds University
One-Lung Ventilation, Thoracic Surgery, Video-Assisted
Comparison Between CPAP and HFJV During One-lung Ventilation in VATS
This study compares two ventilatory techniques (continuous positive airway pressure vs high frequency jet ventilation) during one-lung ventilation (OLV) in video-assisted thoracic surgery (VATS).
- Trial name
- NCT03296449
- Testing
- CPAP, HFJV
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Hospital General Universitario de Alicante
Postoperative Cough, Thoracoscopy
Effects of Vagus Nerve Pulmonary Branch Block on Postoperative Cough After VATS Lung Resection
Postoperative cough after pulmonary resection is a common issue seen after thoracic surgeries, hindering patients' recovery and affecting their postoperative quality of life.
- Conditions
- Postoperative Cough, Thoracoscopy, Pulmonary Resection, Vagus
- Trial name
- NCT06500949
- Testing
- Vagus Nerve Pulmonary Branch Block, Vagus Nerve Pulmonary Branch Injection
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Erector Spinae Muscle Plane Block, Serratus Anterior Muscle Plane Block
Analgesic Non Inferiority of the Thoracic Bi-block in Comparison With Thoracic Epidural for VATS.
Video-Assisted thoracic surgery (VATS) is the standard treatment for localized lung cancer. However, there is no consensus on analgesic management in patients undergoing VATS.
- Conditions
- Erector Spinae Muscle Plane Block, Serratus Anterior Muscle Plane Block, Video-Assisted Thoracic Surgery, Lung Cancer
- Trial name
- ANESSTEVATS (NCT04538235)
- Testing
- Thoracic Regional Analgesia
- Where
- France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Montpellier
Lung Cancer, Surgery--Complications
Assessment of the 90-day Mortality Risk Score After VATS Lobectomy
A five classes (A-E) aggregate risk score predicting 90-day mortality after video-assisted thoracoscopic lobectomy for lung cancer, including as independent factors male sex (3 points), carbon monoxide lung diffusion capacity…
- Conditions
- Lung Cancer, Surgery--Complications, Morality
- Trial name
- NCT04799509
- Testing
- VATS lobectomy
- Volunteers
- 2,209 people
- Sponsor
- Università degli Studi dell'Insubria
Video-assisted Thoracoscopic Surgery, Lung Cancer
Intraoperative Conversion During Video-assisted Thoracoscopy Resection for Lung Cancer Does Not Alter Survival
Anatomical resection with systematic lymph-node dissection is currently the standard of care for the treatment of early stage non-small cell lung cancer.
- Conditions
- Video-assisted Thoracoscopic Surgery, Lung Cancer, Lobectomy, Survival
- Trial name
- ICVATR (NCT04663191)
- Testing
- anatomical resection
- Where
- France
- Volunteers
- 843 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Lung Cancer
Pulmonary Artery Sealing Using the HARMONIC ACE+ Shears(HS) for VATS Lobectomy
VATS anatomical lung resection provides an effective minimally invasive treatment strategy for stage I and II lung cancer. VATS lobectomy is associated with significantly less postoperative atrial fibrillation, blood transfusion…
- Trial name
- NCT01975623
- Testing
- HARMONIC ACE®+ Shears (HS)
- Where
- Canada
- Volunteers
- 47 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Postoperative Pain
Effects of Continuous Infusion of Intravenous Nefopam on Postoperative Pain and Opioid Consumption After VATS
This prospective, randomized, double-blinded study is designed to evaluate the postoperative analgesic effect of the continuous infusion of intravenous nefopam in patients undergoing video-assisted thoracic surgery (VATS).
- Trial name
- NCT04450355
- Testing
- Nefopam 80mg/day, Normal saline
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Seoul National University Hospital
Postoperative Pain Management, Video-assisted Thoracoscopic Surgery (VATS)
Analgesic Effectiveness of SPSIPB Versus Thoracic Epidural and Systemic Opioid Analgesia After VATS (SPSIPB-VATS)
This prospective observational study aims to compare the postoperative analgesic effectiveness of three commonly used pain management strategies in video-assisted thoracoscopic surgery (VATS): Serratus Posterior Superior…
- Conditions
- Postoperative Pain Management, Video-assisted Thoracoscopic Surgery (VATS), Thoracic Epidural Analgesia, Serratus Posterior Superior Intercostal Plane Block
- Trial name
- SPSIPB-VATS (NCT07238348)
- Volunteers
- 120 people
- Sponsor
- Karadeniz Technical University
Lung Cancers, Metaverse
Extended Reality (XR)-Assisted CT Localization of Pulmonary Nodules
Extended Reality (XR)-Assisted CT Localization of Pulmonary Nodules
- Conditions
- Lung Cancers, Metaverse, Extended Reality (XR)
- Trial name
- NCT07434167
- Testing
- Extended Reality (XR)-Assisted CT Localization of Pulmonary Nodules
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Lung Neoplasms, Surgery
Comparison Between Wedge Resection and Segmentectomy for Ground Glass Opacity- Dominant Stage IA NSCLC
The purpose of this study is to evaluate whether the long-term outcome and safety of wedge resection are comparable to segmentectomy for the surgical treatment of early stage (IA) non-small cell lung cancer (NSCLC). Zhang et al.
- Trial name
- NCT02718365
- Testing
- Wedge resection, Segmentectomy
- Where
- China
- Volunteers
- 1,382 people
- Sponsor
- West China Hospital
Intubation
Nonintubated Versus Intubated Anesthesia in Video-assisted Thoracic Surgery
The purpose of this study is to compare to the patients undergoing nonintubated general anesthesia with laryngeal mask and undergoing intubated general anesthesia with double-lumen endotracheal intubation in Video-assisted…
- Trial name
- NCT04253795
- Testing
- Laryngeal mask, double lumen tube
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Antalya Training and Research Hospital
Anesthesia Recovery Period, Pain, Postoperative
Controlled-Release Oxycodone For Postoperative Analgesia After Video-Assisted Thoracic Surgery
The main hypothesis of this study is that preoperative administration of controlled-release (CR) oxycodone may reduce acute postoperative pain and improve time to discharge from the post-anesthesia care unit in patients…
- Trial name
- NCT00681174
- Testing
- Morphine, oxycodone, Paravertebral block
- Where
- Italy
- Volunteers
- 22 people
- Sponsor
- University of Parma
VATS Lobectomy, VATS Segmentectomy
Care Pathway for Patients Undergoing VATS Lobectomy or Segmentectomy
The goal of this study is to create a unified SOP for care of subjects undergoing VATS lobectomy and segmentectomy by members of the Division of Thoracic Surgery.
- Conditions
- VATS Lobectomy, VATS Segmentectomy, Care Pathway, Lung Nodule
- Trial name
- NCT03024294
- Testing
- Post-operative care pathway for patients undergoing VATS lobectomy or segmentectomy
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Postoperative Pain After Thoracic Surgery, Postoperative Pain
Comparison of IV Analgesia Protocols After the Regional Block's Effect Diminishes in Thoracic Surgery
The purpose of this study is to compare the effectiveness of three different intravenous (IV) patient-controlled analgesia (PCA) regimens-Fentanyl, Tramadol, and Ibuprofen-in managing postoperative pain and respiratory…
- Conditions
- Postoperative Pain After Thoracic Surgery, Postoperative Pain, Thoracic Surgery, Video Assisted, Patient Controlled Analgesia
- Trial name
- NCT07610408
- Testing
- Fentanyl IV PCA, Tramadol IV PCA, Ibuprofen IV PCA
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people
- Sponsor
- Ankara Etlik City Hospital
Small Pulmonary Nodules, Pulmonary Nodule Localization
Monarch Robotic Bronchoscopy for Lung Nodule ICG Dye Marking Before VATS
This is a single-center, prospective, single-arm clinical study conducted at Beijing Cancer Hospital to evaluate the effectiveness, safety, and learning curve of preoperative indocyanine green (ICG) dye marking mixed with…
- Conditions
- Small Pulmonary Nodules, Pulmonary Nodule Localization, Lung Cancer (Suspected or Confirmed), Video-assisted Thoracoscopic Surgery (VATS)
- Trial name
- REALM (NCT07177924)
- Testing
- Monarch RAB with CBCT-guided ICG Dye Marking
- Volunteers
- 50 people
- Sponsor
- Peking University Cancer Hospital & Institute
Analgesia
Comparison of the Ultrasound-guided Paravertebral Nerve Block With Liposomal Bupivacaine Versus Ropivacaine for Post-Surgical Pain After Video-Assisted Thoracoscopic Surgery
Prospective, randomized, and controlled trial to compare the postoperative pain management of paravertebral nerve block with liposomal bupivacaine to ropivacaine in patients undergoing elective thoracoscopic surgery.
- Trial name
- NCT06405724
- Testing
- Liposomal bupivacaine, Ropivacaine
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Feng Gao