Clinical trials: VExUS
Venous Congestion, Heart Failure Acute
Vexus Assessment and Natriuresis-guided Diuretic Therapy in Acute Heart Failure
This study evaluates whether natriuresis-guided diuretic therapy improves outcomes in patients with acute heart failure (AHF) and severe congestion.
- Conditions
- Venous Congestion, Heart Failure Acute, VExUS, Diuretics
- Trial name
- VANTAGE-HF (NCT07558798)
- Testing
- Natriuresis-guided escalation of loop diuretics
- Where
- 2 sites in Norway
- Volunteers
- 270 people
- Sponsor
- University Hospital, Akershus
Acute Kidney Injury, VExUS
VExUS Score and AKI in Critically Ill Adult patients-a Prospective Observational Study.
Introduction Renal perfusion is dependent on the renal perfusion pressure across the renal capillaries. Venous congestion due to excess fluid therapy can drastically reduce the renal perfusion pressure in spite of a normal mean…
- Trial name
- NCT06889116
- Where
- Nepal
- Volunteers
- 52 people
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Hemodialysis Patient, Dry Weight
VEXUS and Assessment of Dry Weight of Patients on Hemodialysis
This is a prospective, single-arm study that will be conducted over a period of 24 weeks. The same maintenance HD patients will be followed sequentially in two study phases, with each patient serving as their own control.
- Trial name
- NCT07721636
- Testing
- ULTRASOUND for volume assessment
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Alexandria University
Esophageal Cancer (EsC), Postoperative Pulmonary Complications (PPCs)
Effect of VExUS Score on Postoperative Pulmonary Complications in Elderly Patients
Brief Summary This clinical trial aims to evaluate whether perioperative goal-directed fluid therapy (GDFT) targeting a venous excess ultrasound (VExUS) score of 1 can reduce postoperative pulmonary complications (PPCs) in…
- Trial name
- NCT07691944
- Testing
- VExUS Score-Guided Intraoperative Goal-Directed Fluid Therapy
- Volunteers
- 126 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Hypertension (HTN), Hemodialysis
Usefulness of the VExUS Protocol for Dry-Weight Adjustment in Hemodialysis Patients: The Multicenter VExHD Study
The objective of this prospective observational study is to determine the utility of ultrasonographic assessment using the VExUS protocol for dry weight adjustment in clinically euvolemic patients undergoing hemodialysis.
- Trial name
- VEX-HD (NCT07659197)
- Testing
- Increased ultrafiltration, No increase in ultrafiltration
- Where
- Spain
- Volunteers
- 72 people
- Sponsor
- Fundación Senefro
Acute Kidney Injury, Renal Insufficiency, Acute
VExUS-guided Fluid Management in Patients With Acute Kidney Injury in the Intensive Care Unit
A quasi experimental study that aims to verify whether the incorporation of VExUS in patients with AKI in the Intensive Care Unit (ICU) may prompt tailored interventions to increases the number of days free from Renal Replacement…
- Conditions
- Acute Kidney Injury, Renal Insufficiency, Acute, Kidney; Disease, Acute, Critical Illness
- Trial name
- AKIVEX (NCT05240833)
- Testing
- VExUS Score
- Where
- Brazil
- Volunteers
- 55 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Acute Kidney Injury After Open Heart Surgery, Venous Congestion After Open Heart Surgery
Evaluation of the Association Between the VEXUS Score and Hemodynamic Status and the Occurrence of Acute Kidney Injury After Open-Heart Surgery
Acute kidney injury is a common complication after cardiac surgery with cardiopulmonary bypass and is associated with prolonged intensive care unit stay, increased morbidity, and mortality.
- Trial name
- NCT07805564
- Where
- Vietnam
- Volunteers
- 135 people
- Sponsor
- Hanoi Medical University
Venous Congestion, Postoperative Care
Portal and Splenic Venous Pulsatility in Postoperative Critically Ill Patients
Venous congestion is common in critically ill postoperative patients and may be associated with adverse outcomes. Doppler ultrasound assessment of venous flow patterns, including portal venous pulsatility, is increasingly used to…
- Trial name
- PULSE-ICU (NCT07826481)
- Volunteers
- 60 people
- Sponsor
- Hospital Universitario de Gran Canaria Doctor Negrín
Thoracic Surgery With One-lung Ventilation, VExUS
Effect of VExUS Ultrasound Protocol (Venous Excess Ultrasound) on Perioperative Fluid Management, on the Incidence of Postoperative Pulmonary Complications and Postoperative Acute Kidney Injury in Patients Undergoing Thoracic Surgery
This study aims to investigate the effect of a VExUS ultrasound guided protocol of perioperative fluid management within a goal-directed therapy framework, on postoperative respiratory complications, and the occurrence of acute…
- Conditions
- Thoracic Surgery With One-lung Ventilation, VExUS, Fluid Management, Acute Kidney Injury
- Trial name
- VEXUS (NCT07258875)
- Testing
- Venous Excess Ultrasound, Standard of Care (SOC)
- Where
- Greece
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of Crete
Heart Failure, Acute Kidney Injury
Treatment According to Venous Excess Ultrasound Score in Patients With Heart Failure
Heart failure is a syndrome that progresses with symptoms and signs caused by cardiac dysfunction and results in a shortened life expectancy (1).
- Trial name
- NCT06341816
- Testing
- VEXUS score, NGAL
- Volunteers
- 100 people
- Sponsor
- Inonu University
Cardiac Surgical Procedures, Hemodynamics
Structured Hemodynamic Assessment to Guide Care After Cardiac Surgery
This multicenter pilot randomized controlled trial will evaluate whether providing treating physicians with a structured hemodynamic assessment influences care after cardiac surgery.
- Conditions
- Cardiac Surgical Procedures, Hemodynamics, Fluid Therapy, Acute Kidney Injury
- Trial name
- UTF-in-CVICU (NCT07792707)
- Testing
- Expert Report of a Structured Hemodynamic Assessment, Standard Care (in control arm)
- Where
- 2 sites in Canada
- Volunteers
- 75 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Sepsis, Sepsis and Septic Shock
Hemodynamic Venous Congestion Ultrasound (VExUS) by ICU Nurses in Sepsis Patients.
Sepsis is a serious condition where the body's immune response to infection overreacts, leading to organ damage and death. Venous congestion, a buildup of blood in the veins, can occur in sepsis and contribute to organ injury.
- Conditions
- Sepsis, Sepsis and Septic Shock, Sepsis at Intensive Care Unit, Intensive Care Nurses
- Trial name
- VEXIVAN (NCT07406750)
- Testing
- Education in performing hemodynamic diagnostic ultrasound of venous congestion, Hemodynamic diagnostic ultrasound of venous congestion
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Region Örebro County
Critically Ill Patients, Septic Shock
Vexus-guided Fluid Management in Patients With Septic Shock After the Resuscitation Phase
It is well recognized the association between fluid volume administered and positive fluid balance with adverse outcomes . Active fluid removal is widely practiced in an attempt to mitigate this potential damage.
- Trial name
- VEXUS (NCT06227702)
- Testing
- Fluid management according to Venous Excess Ultrasound (VExUS) Score
- Volunteers
- 200 people
- Sponsor
- Federal University of São Paulo
Pulmonary Arterial Hypertension (PAH), Pulmonary Arterial Hypertension (PAH) (WHO Group 1 PH)
Incorporating the Venous Excess Ultrasound Score (VExUS Score) Into Contemporary Haemodynamic Risk Assessment in Pulmonary Arterial Hypertension: The INVEXUS-PAH Study
This prospective observational study aims to evaluate the relationship between the Venous Excess Ultrasound Score (VEXUS) and the ESC/ERS 2022 simplified four-strata risk assessment model in adult patients with World Health…
- Trial name
- INVEXUS-PAH (NCT07266012)
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Istanbul University - Cerrahpasa
Renal Failure, Acute Renal Failure
External Validation of the VExUS Score for the Prediction of Acute Renal Failure in Cardiac Surgery
Acute renal failure is a frequent complication associated with significant morbidity and mortality in postoperative cardiac surgery.
- Conditions
- Renal Failure, Acute Renal Failure, Renal Insufficiency, Acute Renal Insufficiency
- Trial name
- ValiVexus (NCT05640518)
- Where
- France
- Volunteers
- 119 people
- Sponsor
- University Hospital, Grenoble
Acute Heart Failure (AHF), Fluid Over-load
Training Medical Residents in the Use of the Venous Excess UltraSound (VExUS) Score for Bedside Volume Assessment.
This randomized controlled trial evaluates the effectiveness of two training approaches (in-person versus remote) for teaching medical residents to apply the Venous Excess Ultrasound (VExUS) score for bedside volume assessment in…
- Conditions
- Acute Heart Failure (AHF), Fluid Over-load, Congestion, Congestion, Venous
- Trial name
- NCT07541768
- Testing
- In-person VExUS Training Program, Remote VExUS Training Program, No intervention
- Where
- Switzerland
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Cardiorenal Syndrome, Acute Kidney Injury
Effect on Kidney Function Recovery Guiding Decongestion With VExUS in Patients With Cardiorenal Syndrome 1
During cardiorenal syndrome type 1 (CRS1) vascular congestion is the major contributor to worsening renal function, but promoting decongestion with routine clinical evaluation is ineffective in some patients.
- Conditions
- Cardiorenal Syndrome, Acute Kidney Injury, Decompensated Heart Failure, Fluid Overload
- Trial name
- NCT05927285
- Testing
- Vexus, Control group
- Where
- Mexico
- Volunteers
- 140 people
- Sponsor
- Hospital Civil de Guadalajara
Blood Volume Expansion
Evaluation of the Venous Excess Ultrasound Score (VExUS) After Circulating Volume Modification in Children.
Venous overload has an impact on peripheral organ perfusion and on the short- and long-term prognosis of intensive care patients. The VExUS ultrasound score is a new tool whose parameters can be used to estimate this impact.
- Trial name
- VExUS-Mod (NCT06695546)
- Testing
- VExUS evaluation ultrasound
- Where
- France
- Volunteers
- 67 people
- Sponsor
- University Hospital, Toulouse
Acute Kidney Injury, Cardiac Surgery Associated - Acute Kidney Injury
Prevention and Treatment of AKI VEXUS Guided Post Cardiac Surgery
The main goal of this clinical trial is to learn if evaluation by ultrasound of venous congestion of liver and kidneys can guide treatment and prevent and treat acute kidney injury post cardiac surgery (CSA-AKI).
- Trial name
- VEXAKI (NCT06972082)
- Testing
- VEXUS
- Where
- Greece
- Volunteers
- 304 people
- Sponsor
- Onassis Cardiac Surgery Centre
Venous Congestion
VEXUS-REA : Evaluation of Ultrasound Parameters of Venous Congestion in Patients in a Medical Intensive Care Unit
Shock is a common and serious cause of admission to intensive care. Vascular filling is one of the cornerstones of shock treatment, aimed at increasing cardiac output and restoring adequate organ perfusion through rapid…
- Trial name
- VEXUS-REA (NCT07438015)
- Testing
- Venous ultrasound (inferior vena cava, portal vein, suprahepatic vein, and renal vein to calculate the VEXUS score ; femoral vein and popliteal vein)
- Where
- France
- Volunteers
- 525 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon