Clinical trials: VV ECMO
Neurocognitive Dysfunction
Neuro-cognitive Function 1 Year Post ICU Discharge Among VV ECMO Survivors
In the past three years, in the general intensive care unit in Meir medical center, 25 patients were treated with ECMO, of which two patients were treated with VA ECMO and the rest with VV ECMO.
- Trial name
- NCT06224088
- Testing
- VV ECMO
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Meir Medical Center
ARDS, Human, Extracorporeal Membrane Oxygenation
Use of Prone Position Ventilation in Danish Patients With COVID-19 Induced Severe ARDS Treated With VV-ECMO
Prone position ventilation was used 220 times in 44 out of 68 patients with severe COVID-19 induced ARDS treated with VV-ECMO. PPV treated patients did not benefit from PPV and the incidence of PPV related adverse events was high
- Conditions
- ARDS, Human, Extracorporeal Membrane Oxygenation, COVID-19 Acute Respiratory Distress Syndrome, Prone Position
- Trial name
- NCT05693051
- Testing
- Prone position ventilation
- Where
- 2 sites in Denmark
- Volunteers
- 68 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Extracorporeal Membrane Oxygenation Complication, ARDS (Acute Respiratory Distress Syndrome)
RECOMMEND Platform Trial
The goal of this platform trial is to determine the efficacy, safety and cost-effectiveness of various interventions in patients with acute cardiorespiratory failure requiring extracorporeal membrane oxygenation (ECMO) The main…
- Conditions
- Extracorporeal Membrane Oxygenation Complication, ARDS (Acute Respiratory Distress Syndrome), Intensive Care Medicine, Cardiac Arrest (CA)
- Trial name
- RECOMMEND (NCT06526533)
- Testing
- Liberal RBC Transfusion, Restrictive RBC Transfusion
- Where
- 3 sites in Australia
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Australian and New Zealand Intensive Care Research Centre
VV ECMO, Bleeding
Incidence of Bleeding, Thrombosis and Transfusion Requirements in ICU Patients With COVID-19 Supported With Veno-venous Extracorporeal Membrane Oxygenation
The investigators aim to assess the risk of bleeding and thrombo-embolic complications as well as benefit and harm of blood product transfusion and anticoagulation therapy in adult ICU patients with COVID-19 supported with V-V…
- Conditions
- VV ECMO, Bleeding, Thrombosis, Transfusion Adverse Reaction
- Trial name
- NCT07352072
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Critical Illness, Anticoagulation
Efficacy and Safety of Nafamostat Mesylate for VV-ECMO Anticoagulation
The purpose of this study was to compare the efficacy and safety of nafamostat mesylate and unfractionated heparin during ECMO anticoagulation in critically ill patients.
- Trial name
- NCT05555641
- Testing
- Nafamostat Mesylate, Unfractionated Heparin
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Xiaobo Yang, MD
Ards, Mechanical Ventilation Pressure High
Prognostic Value of Respiratory System Compliance Under VV-ECMO on 180-day Mortality in COVID-19 ARDS.
Mortality of patients with COVID-19 associated acute respiratory distress syndrome (CARDS) treated with veno-venous extra-corporal membrane oxygenation (vv-ECMO) is increasing over time since the beginning of the COVID-19…
- Conditions
- Ards, Mechanical Ventilation Pressure High, Extracorporeal Membrane Oxygenation
- Trial name
- COMPLIECMO (NCT05341687)
- Testing
- No applicable
- Where
- France
- Volunteers
- 122 people
- Sponsor
- Central Hospital, Nancy, France
ARDS (Acute Respiratory Distress Syndrome)
CUrrent Practices of Intensive Care for the Management of Acute Respiratory Distress Syndrome in EurOpe.
This study seeks to gain a comprehensive understanding of current ARDS management practices across European ICUs, with a particular focus on the use of LTV and PP therapy, which have been shown to improve outcomes in ARDS…
- Trial name
- CUPIDO (NCT06714201)
- Volunteers
- 100 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Covid-19
Bicentric Study on the Use of ECMO-VV or VA for Severe ARDS Associated With Covid-19
Describes the cohort of patients receiving ECMO-VV or ECMO-VA in the management of severe ARDS refractory to SARS-CoV-2 in the Strasbourg and Louvain centres
- Trial name
- ECMO-SL-CoV-2 (NCT04446286)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Strasbourg, France
ARDS Due to Disease Caused by SARS Co-V-2
Prediction of Conversion From Vv-ECMO to Va-ECMO in COVID-19 Patients
In December 2019, cases of a novel lung disease, later referred to as COVID-19, were first reported in China. The virus SARS-CoV-2 was identified as the causative agent.
- Trial name
- ECMOPred-vvva (NCT05910996)
- Testing
- Conversion from vv-ECMO to va-ECMO
- Where
- Austria
- Volunteers
- 99 people
- Sponsor
- Kepler University Hospital
Hemorrhage
New Anticoagulation Strategies of VV-ECMO
Effective and normative anticoagulation is one of the most important components of Extracorporeal membrane oxygenation (ECMO) management.
- Trial name
- NCT03497338
- Where
- China
- Sponsor
- Xiao Tang
ECMO, Mplementation of a Veno-venous VV or Veno-arterial VA
EVOLUTION OF D-DIMER AS A MARKER OF BLEEDING RISK ON ECMO
ECMO (extracorporeal membrane oxygenation) is a life-saving device, used in intensive care to treat severe respiratory or cardiac failure. However, it carries a high risk of serious life-threatening bleeding.
- Conditions
- ECMO, Mplementation of a Veno-venous VV or Veno-arterial VA, INTENSIVE CARE
- Trial name
- ECMOstase2 (NCT07039513)
- Testing
- Blood sampling collection
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Venovenous Extracorporeal Membrane Oxygenation, Recirculation
Measurement of Recirculation During Venovenous Extracorporeal Membrane Oxygenation (VV ECMO)
This study is to test the usefulness of ultrasound dilution recirculation measurements in patients receiving venovenous extracorporeal membrane oxygenation as therapy.
- Trial name
- NCT00920062
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Transonic Systems Inc.
ARDS (Acute Respiratory Distress Syndrome), VV ECMO
Trial of Total Lung Protective Ventilation in Adult VV-ECMO Patients With Severe ARDS
The purpose of this study is to find a better way to protect the lungs of patients with Acute Respiratory Distress Syndrome (ARDS) who are being treated with a mechanical ventilator in addition to an extracorporeal membrane…
- Trial name
- PROTECT-ARDS (NCT07790133)
- Testing
- Mechanical Power Targeted Ventilation
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Virginia
ECMO, Heparin
Veno-venous Extracorporeal Membrane Oxygenation (VV-ECMO) Heparin Study
This single-center, open-label study will evaluate the safety and efficacy of subcutaneous heparin anticoagulation compared to the standard of care systemic intravenous anticoagulation during veno-venous extracorporeal membrane…
- Conditions
- ECMO, Heparin, Respiratory Failure
- Trial name
- NCT04496362
- Testing
- subcutaneous heparin anticoagulation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Baylor Research Institute
COVID-19 Acute Respiratory Distress Syndrome, Extracorporeal Membrane Oxygenation Complication
Quality of Life 1y and 2 y After VV-ECMO for COVID-19
This study aims to investigate the quality of life and the outcome after veno-venous extracoporeal membrane oxygenation (ECMO) support fir severe acute respiratory syndrome (ARDS) in COVID-19 patients.
- Conditions
- COVID-19 Acute Respiratory Distress Syndrome, Extracorporeal Membrane Oxygenation Complication, Quality of Life, Death
- Trial name
- NCT05780255
- Testing
- VV-ECMO
- Where
- Belgium
- Volunteers
- 28 people
- Sponsor
- University Hospital, Ghent
Respiratory Distress Syndrome, Adult
New Lung Ventilation Strategies Guided by Transpulmonary Pressure in VV-ECMO for Severe ARDS
Extracorporeal membrane oxygenation (ECMO) has been widely used in patients with severe acute respiratory distress syndrome (ARDS).
- Trial name
- NCT02439151
- Testing
- New lung ventilation strategy, Conventional ventilation strategy
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Rui Wang
Acute Respiratory Distress Syndrome
Full-Course ECMO Strategy for Moderate-to-Severe ARDS
China faces major challenges in the ECMO management of patients with moderate-to-severe ARDS, including substantial heterogeneity in clinical practice, low weaning success rates, and high complication rates.
- Trial name
- NCT07726953
- Testing
- Full-Course ECMO Management Pathway, Usual Care
- Where
- 39 sites in China
- Volunteers
- 500 people
- Sponsor
- Southeast University, China
Acute Respiratory Distress Syndrome, Extracorporeal Membrane Oxygenation
Effect of Transpulmonary MP on Prognosis of Patients With Severe ARDS Treated With VV-ECMO
Venovenous extracorporeal membrane oxygenation (VV-ECMO) is a salvage treatment for severe acute respiratory distress syndrome (ARDS).
- Conditions
- Acute Respiratory Distress Syndrome, Extracorporeal Membrane Oxygenation, Mechanical Power, Transpulmonary Mechanical Power
- Trial name
- NCT06062212
- Testing
- Transpulmonary pressure
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Beijing Chao Yang Hospital
ECMO Treatment, ARDS
Hemodynamic Monitoring and Fluid Responsiveness in Venoarterial Extracorporeal Membrane Oxygenation (VA ECMO) - "HemodynamECMOnitoring-VA Study"
In extracorporeal membrane oxygenation (ECMO), blood is drawn out of the body via tubes, oxygenated in an artificial lung; and then pumped back into the blood vessels.
- Conditions
- ECMO Treatment, ARDS, Pneumonia, Intensive Care
- Trial name
- NCT06593756
- Testing
- Transthoracic Echocardiography, Uncalibrated Pulse Contour Analysis, Transpulmonary Thermodilution/Calibrated Pulse Contour Analysis
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Medical University of Vienna
Acute Respiratory Distress Syndrome, Acute Respiratory Failure
Pronation During Veno-venous Extra Corporeal Membrane Oxygenation
The Acute Respiratory Distress Syndrome (ARDS) is defined by a recent (within 1 week) respiratory failure, not fully explained by cardiac failure or fluid overload.
- Trial name
- NCT05198986
- Testing
- Prone Position during Extra Corporeal Membrane Oxygenation (ECMO)
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- University Magna Graecia